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      • SCOPUSKCI등재

        d-Tubocurarine 의 혈관내 주입속도에 따른 혈압변화에 관한 임상적 고찰

        김원,김현수,신옥영,권무일 대한마취과학회 1981 Korean Journal of Anesthesiology Vol.14 No.3

        d-Tubocurarine is one of the non-depolarizing muscle relaxants which is most commonly used in clinical situations d_Tc is used as a selective muscle relaxant in hypertensive patients or patients for renal transplantation. The most common side effect of d_Tc is a dose-related fall in arterial pressure. Although the cause of the hypotension is still controversial, the two mechanisms most frequently suggested are ganglionic block and histamine release. d_Tc is an actice ganglionic blocking agent. However, because its potency at the neuromuscular junction greater than at the ganglia, there is some doubt that a clinical concentration of d_Tc is sufficient to cause hypotension. Histamine release may play a role in this blood pressure reduction. Indeed, decrease in blood pressure produced by d_Tc have been shown to be less when the muscle relaxant was preceded by an antihistamine. The amount of histamine release substance depends on plasma levels of the drug achieved and thus on the rapidity of intravenous administration of that drug. Ifd-Tc produces histamine release, then slow intravenous unjection would be associated with minimal histamine release and a resulting attenuation of the typical blood pressure reduction that follow's this drugs injection. Therfore, we measured changes in mean arterial pressure(MAP) and heart rate in patients anesthetized with nitrous oxide-halothane during and after the intravenous injection of d_Tc at varying rates of administration. The results are as follows; 1) Group 1 : Maxium reductions in MAP were present 3 minutes following d_Tc injection over 1 second(81±3 torr). Comparative with control group(99±6 torr), significant reduction was revealed(18.1%). 2) Group 2 : Decrease in MAP 3 minutes after administration of d_Tc over 90 seconds(11.1%) were intermediate between the other injection rates. 3) Group 3 : Decrease in MAP 3 minutes after d_Tc administration was significantly less in patients receiving the drug over 180 seconds(5.1%). Heart rate did not change significantly after d_Tc injection regardless of the rate of administration.

      • KCI등재후보

        인접건물에 의한 고층건축물의 피크국부풍압 분포 I - 피크풍압분포 및 풍압파워스펙트럼 중심으로 -

        김원,김윤석,타무라 유키오,요시다 아키히토 한국풍공학회 2011 한국풍공학회지 Vol.15 No.1

        Local peak pressures between two buildings were studied by using wind tunnel experiments for various locations and height ratios of an interfering building and wind directions. The measured local peak pressure coefficients were compared to those obtained previously from a study on an isolated building. The experimental results have been examined and presented from the viewpoint of cladding design. The results show that at wind direction θ=135˚, minimum peak pressure coefficient on the front surface of the principal building with the interfering building for H_r≥1.5 at (S_x,S_y)=(1.5B,0) tends to increase generally and the smallest values of minimum peak pressure coefficients on the front surface of the principal building were -4.7(H_r=1.5), -5.7(H_r=2.0), while the smallest value of minimum peak pressure coefficient on the isolated building was -3.5. It can be explained by the fact that an increase in energies is associated with the reattaching shear layers on the principal building caused by high turbulence, thus significantly increasing the suction. 본 연구에서는 풍동실험을 통해 인접건축물의 다양한 높이비, 위치와 풍향에 따른 고층건축물에 작용하는 피크풍압계수에 대하여 조사하였다. 그리고 피크풍압계수는 Cook and Mayne의 제안식을 이용하여 산출하였다. 실험결과는 우선적으로, 인접건축물의 유무에 따른 최대 및 최소풍압계수의 분포도를 통해 비교 분석하였다. 풍동실험결과 풍향 135도에서 인접건축물의 높이비가 H_r≥1.5이고, (S_x,S_y)=(1.5B,0)에 위치할 때, 대상건축물의 정면에 작용하는 최소풍압계가 단독건축물에 작용하는 최소풍압계수(-3.5)에 비해 전반적으로 크게 나타났으며, 최소풍압계수의 최소값은 정면의 최상부 코너 부근에서 -4.7(H_r=1.5), -5.7(H_r=2.0)으로 나타났다. 본 연구의 결과는 CFD 해석 결과의 정당성 입증과 두동 이상으로 이루어진 고층건축물의 초기설계단계에서 상호간섭효과로 인한 외장재용 풍하중을 대략적으로 평가하는데 유용하게 사용할 수 있을 것이다.

      • KCI등재

        상호간섭효과에 의한 고층건축물에 작용하는 국부풍압에 관한 연구

        김원술(Kim Won-Sul),타무라 유키오(Tamura Yukio),요시다 아키히토(Yoshida Akihito) 대한건축학회 2010 大韓建築學會論文集 : 構造系 Vol.26 No.1

        Most wind codes or standards have been established for isolated buildings. In real environment, the effect of wind load on a group of high-rise buildings could be quite different from that of isolated tall building and its surrounding tall buildings can either increase or decrease not only the whole wind load, but also wind loads locally affecting cladding. Some Wind Standards such as AIJ(2004), AS1170.2(1989) and ASCE7-05(2005) have incorporated design wind loads on buildings and cladding due to effects of mutual interference by neighboring and structures, but there is no concrete information. In this paper, local peak wind pressure coefficients between two identical tall buildings were studied by using wind tunnel experiments, under various locations of interfering buildings and wind directions. The measured peak wind pressure coefficients were compared with those previously obtained from the study of an isolated building. In addition, this study also investigated the interference effects of smallest minimum wind pressure coefficient under various wind angles. The interference effects were examined and presented in detail. The results show that the local peak wind pressure coefficients on the walls of a principal building largely depended on the wind angles and the location of interfering buildings in the wake region.

      • KCI등재

        나선형 초고층건물의 공력불안정 진동과 공력감쇠에 관한 연구

        김원,아키히토 요시다,타무라 유키오,이진학,Kim, Wonsul,Yoshida, Akihito,Tamura, Yukio,Yi, Jin-Hak 한국전산구조공학회 2016 한국전산구조공학회논문집 Vol.29 No.1

        본 논문에서는 변위응답 및 가속도 응답의 저감 효과에 있어서, 유리한 형상인 $180^{\circ}$ 나선형(Helical $180^{\circ}$) 초고층건물을 대상으로 풍진동실험을 수행하여 나선형 초고층건물의 공력불안정 진동 특성 및 공력감쇠 특성을 조사하였고, 정방형 초고층건물의 결과와 비교분석 하였다. 본 연구에서의 공력감쇠율은 RD법(random decrement technique)을 이용하여 평가하였다. RD법에 의해 평가된 공력감쇠율은 기존문헌 및 준정상가정이론 결과와 비교 검증하였다. 실험결과, 공력진동 실험결과 $180^{\circ}$ 나선형모형의 풍직각방향에 대한 공력불안정 진동은 발생하지 않는 것이 확인되었다. 정방형과 $180^{\circ}$ 나선형 형상에 대한 공력감쇠율을 살펴보면, X방향에 대한 공력감쇠율은 무차원 풍속이 증가와 비례하여 점진적으로 증가하는 경향이 나타났다. 반면, Y방향에 대한 공력감쇠율은 정방형모형과 매우 다른 양상이 나타나는 것을 알 수 있었다. In this paper, aeroelastic instability and aerodynamic damping ratio of a helical $180^{\circ}$ model which shows better aerodynamic behavior in both along-wind and crosswind responses on a super tall building was investigated by an aeroelastic model test, and the aerodynamic damping ratio was evaluated from the wind-induced responses of the model by using Random Decrement Technique. Aerodynamic damping ratios evaluated in this study were verified through comparison with previous results obtained by quasi-steady theory. As a result, the aeroelastic instability of the helical $180^{\circ}$ model in crosswind direction were not occurred for any conditions with increasing the reduced wind velocity while the square model generally encounters aeroinstability due to the vortex shedding. The aerodynamic damping in along-wind direction for the helical $180^{\circ}$ and the square model increased monotonically both with reduced wind velocity, i.e., there is no relation with modifications of building shapes. On the other hand, in crosswind direction, the characteristics of aerodynamic damping ratio with reduced wind velocity for helical $180^{\circ}$ model were quit different from those of the square model.

      • KCI등재

        인접건축물이 고층건축물의 외장재용 풍하중에 미치는 영향

        김원술(Kim Won-Sul),타무라 유키오(Tamura Yukio),요시다 아키히토(Yoshida Akihito) 대한건축학회 2010 大韓建築學會論文集 : 構造系 Vol.26 No.1

        This paper describes results of wind tunnel experiments performed at Tokyo Polytechnic University to determine interference effects of local peak pressures on an identical pair of tall buildings to establish design cladding pressures. Measured local peak wind pressure coefficients were compared with those for the walls of an isolated building. The results showed the distribution of maximum (minimum) wind pressure coefficients on walls of a principal building with critical locations of an interfering building, as well as smallest minimum wind pressure coefficients on the side walls of the principal building due to interference. Also, the local peak wind pressure coefficients on the walls of the principal building were higher or lower depending on the locations of the interfering building, and were largely induced by the wake separated from the edges of an upwind interfering building. The authors deal with the shielding effects and channeling effects for various relative locations of the interfering building.

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