http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 김요섬 (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
복분자로부터 분리동정한 Lactobacillus plantarum GBL16, 17균주를 포함한 시제품의 장내 미생물 변화
최혜란,이수정,김성웅,이현기,한두원,정이형,장한수,김요섬,권규택 경상국립대학교 농업생명과학연구원 2020 농업생명과학연구 Vol.54 No.4
This study was performed to probiotic including Lactobacillus plantarum stains (GBL16 and 17) isolated from black raspberry identified intestinal microbial changes. The experiment was control (CTL), Probiotic Milk Candy (L. plantarum GBL16 and 17 combination group; PMC) and Bebe Finger Yogurt (BFY) were provided to Balb/c mice for 8 weeks. The number of intestinal lactic acid bacteria was significantly increased in PMC. There was not changed in the total number of bacteria in each group, PMC and BFY showed various changes the abundance of genus Lachnospiraceae, Alistipes. Our finding expected that the modulation of gut microbiota by probiotic was related with the beneficial effects, but further application study to human is necessary. 이 연구는 복분자에서 분리된 Lactobacillus plantarum stain (GBL16 및 17)을 포함한 probiotic에 대해 수행되었으며, 장내 미생물 변화를확인하였다. Balb/c 마우스모델에서 GBL 16, 17을 포함한 시제품인 PMC와 시판중인 유산균 과자 BFY를 8주간 경구 투여 하였다. PMC의투여는 장내 미생물총의 균형을 향상시키고, 장내개선에 긍정적인 영향을 보였다. 맹장을 이용한 NGS 분석을 통해 확인한 결과, 스트레스 후증가하는 양상을 보이는 균인 Lachnospiraceae균이 감소하는 경향을 보였다. Alistipes균의 증가는 염증성 장 질환에 효과가 있을 것으로 판단되나, 추후 더 많은 연구가 필요할 것으로 보인다.
-
최혜란,정이형,육현균,이현기,장한수,김요섬,신대근 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.6
The objective of this study was to evaluate probiotic effects of two Lactobacillus plantarum strains (GBL16 and 17) isolated from black raspberry. Results revealed that the number of GBL16 was gradually decreased as bile salt concentration was increased from 0.3 to 1%. However, GBL17 did not show any difference when GBL17 was applied to 1% bile salt, and it indicates that GBL17 is more tolerant to bile salt than GBL16. GBL17 exhibited higher heat resistance and adhesion ability to Caco-2 cells than GBL16. Regarding gut microbiome, no significant change in the number of total bacteria in intestines of mice after treatment with GBLs was determined. However, the combination of GBL16 and GBL17 significantly increased the number of total bacteria in intestines of mice after they were orally administered. Therefore, the results suggest that both GBL16 and 17 strains could be one of major probiotics that can improve human gut health.
KCI
코리아스칼라연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
