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김예솔,진현정 한국식품유통학회 2022 食品流通硏究 Vol.39 No.2
The COVID-19 outbreak continues for the second consecutive year, consumers’ food consumption patterns are changing. As the number of meals at home increased, household consumption of fresh products and food/beverage products increased, while the restaurant industry significantly decreased. In addition, the decrease in inbound tourists is expected to have a significant impact not only the tourism industry but also on the restaurant industry. However, the overall impact of the food industry due to changes in consumer food consumption has not yet been identified. This paper aims to investigate changes in food demand based on statistical data for 2020 and the first and second quarters of 2021, and estimate the ripple effect of these changes on the entire industry. The food industry was classified into fresh products, food/beverage products, and food service sectors, and variables affecting this sector were set as domestic household consumption, inbound tourist consumption, and food exports. An input-output analysis was used to estimate the ripple effects on production, value-added, and employment. The results of this study will be an important material for understanding the overall damage to the food industry due to COVID-19 and estimating the ripple effect on the entire domestic industry. Moreover, it is expected that it can be used as basic data in policies related to COVID-19, such as consumption promotion policies like market support and coupon provision or emergency financial support for restaurant companies.
폐 절제술 후 걷기 운동을 경험한 폐암 환자의 수술 후 회복 관련 요인
김예솔,최지연,조종호,최모나 대한임상건강증진학회 2021 Korean Journal of Health Promotion Vol.21 No.1
Background: Treatment for lung cancer, which has high incidence and mortality rates, involves lung resection; however, the risk of postoperative pulmonary complications is high. Early walking exercise is a core strategy for preventing complications and promoting postoperative recovery, which is essential for returning to everyday life. This study aims to identify the factors associated with the postoperative recovery of patients who performed walking exercises in an intensive care unit after having a lung resection. Methods: This cross-sectional study collected data from 90 patients on the day before discharge at a tertiary hospital in Seoul between April and June 2019. Patients’ postoperative recovery was measured using the Postoperative Recovery Profile. Results: The mean score for postoperative recovery was 0.70±0.41 out of 3, 0 being none of the problems. Among the five subcategories, the psychological dimension had the highest recovery level at 0.57±0.58, while physical symptoms were rated lowest at 0.89±0.50. As a result of regression analysis, employment status (β=4.353, P=0.005), symptoms of nausea and vomiting during walking (β=0.596, P=0.043), and perceived exertion during walking (β=1.105, P=0.007) were associated with postoperative recovery. Conclusions: The study indicated unemployed patients, those with more nausea and vomiting, and those who perceived severe exertion during walking showed lower perceived postoperative recovery levels. Not only multidisciplinary, patient-tailored interventions to facilitate return to work after surgery but also interventions to control physical symptoms actively should be developed and implemented to achieve higher postoperative recovery levels. Patients also need to exercise at an appropriate subjective level of perceived exertion. 연구배경: 발생률과 사망률이 높은 폐암을 치료하기 위해폐 절제술을 실시하지만, 수술 후 폐 합병증의 위험이 높다. 조기 걷기 운동은 합병증을 예방하고, 일상생활 복귀를 위해 필수적인 수술 후 회복을 향상시키기 위해 중요한 요소이다. 본 연구는 중환자실 내 걷기 운동을 실시한 폐 절제술환자가 퇴원 전 인식하는 수술 후 회복에 영향을 미치는 요인에 대해 살펴보고자 한다. 방법: 본 연구는 조사 연구로, 서울의 일 상급종합병원에서 폐 절제술을 시행하고 중환자실 내 걷기 운동을 실시한후 퇴원을 앞둔 폐암 환자 90명을 대상으로 2019년 4월부터6월까지 자료를 수집하였다. 일반적 특성, 임상적 특성, 중환자실 내 걷기 운동 특성 및 수술 후 회복(역문항)을 조사하였다. 결과: 환자가 인식하는 수술 후 회복의 평균 점수는 3점 만점 중 0.70±0.41점이었고, 심리적 영역이 회복 정도가 가장높았으며 신체적 증상이 가장 낮았다. 또한 통증, 식욕의 변화, 소화기계 장애 순으로 회복이 부족하다고 나타났다. 수술후 회복은 직업이 없는 환자인 경우(β=4.353, P=0.005), 걷기운동 중 오심 및 구토 증상이 심할수록(β=0.596, P=0.043), 주관적 운동자각도가 심각할수록(β=1.105, P=0.007) 수술 후회복 정도가 낮은 것으로 나타났다. 결론: 폐 절제술 환자의 수술 후 회복을 향상시키기 위해신체적 증상을 조절하고 직장 복귀를 촉진시킬 수 있는 다학제적, 환자 맞춤형 중재 개발 및 적용이 필요하다. 또한이들의 수술 후 회복을 위해 적절한 강도로 운동을 실시하는 것이 동반될 필요가 있다.
마우스 대장암 모델 구축 및 항암제 활성 평가를 위한 예비 연구
김예솔,강봉석,이상은,이은주,이경록,정상헌,박정숙 충남대학교 약학대학 의약품개발연구소 2014 藥學論文集 Vol.29 No.-
Abstract – Aberrant crypt foci (ACF) are early imorphological changes observed in rodents after administration of colon-specific carcinogen such as azoxymethane (AOM). ACF are considered to be putative preneoplastic lesions and are widely used as a surrogate biomarker to rapidly evaluate chemopreventive potential of compounds. The size of colorectal cancer was evaluated after administration of three anticancer drugs, 1 parent drug and 2 prodrugs. The body weights of mice were measured daily and considered as a surrogate for evaluation of general wellbeing. Colons were removed, cut along the longitudinal axis and flushed with phosphate-buffered saline. Each colon was cut into three equal lengths and fixed flat between filter papers. The fixed colon sections were stained with methylene blue. The number of ACF per colon, the number of aberrant crypts observed in each focus and the location of each focus were recorded. After single administration of AOM and multiple doses of anticancer drugs, no significant changes in the body weights of the mice was observed which was recorded for 52 days. However, an expected ACF was not observed in any treated groups. These findings suggest the induction of ACF in mice requires the promotion by dextran sulfate sodium as well as the initiation by AOM.