일측성 선상 건선

김신한 ( Shin Han Kim ),이상윤 ( Sang Yoon Lee ),고재완 ( Jae Wan Go ),손현옥 ( Hyun Ok Son ),이상엽 ( Sang Yeop Yi ),조한경 ( Han Kyoung Cho ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.4

Psoriasis vulgaris is one of the most common skin diseases in the world, which is recognized as an autoimmune disease that is caused by genetic and environmental factors. Plaque, guttate, pustular form, and psoriatic erythroderma are known as classical feature of psoriasis with tendency as generalized or sporadic appearance. There are some cases of uncommon forms in the shape and distribution, as nevoid and linear psoriasis. Linear psoriasis is a rare entity and thought as a variant of psoriasis, but its existence is still in debate. Herein, we report an interesting case of 19-year old Korean man with psoriasis, occurring on the right arm, following the line of Blaschko in a linear form. (Korean J Dermatol 2012;50(4):377∼380)

한국 여성의 팽창선줄에 대한 인식도 조사

김신한 ( Shin Han Kim ),이상주 ( Sang Ju Lee ),조한경 ( Han Kyoung Cho ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.9

Background: Striae distensae is a common skin condition that can happen to everyone. Most cases do not have serious problems, but those who are affected may suffer from strong cosmetic stress. There was an epidemiologic study of striae distensae in Korean adolescents. Up to now, variable treatment modalities have been tried including topical application of tretinoin and light-based therapy using pulsed dye lasers or fractional lasers. Objective: To evaluate the prevalence of striae distensae in Korean women and estimate their understanding. Methods: We carried out a survey targeting 256 healthy female adults without a history of medical disease and analyzed the results. Results: The number of patients with striae distensae were 219 (86.0%). Striae distensae was mostly seen at the thigh and calf (84.0%) and longitudinal formed striae, with their long axis parallel to the lines of skin tension, was the most frequent shape (44.0%). The most common color of the striae distensae was white (56.0%) and 78% of patients had experienced this before adulthood. Striae distensae is caused by two major factors, overweight (70.0%) and growth spurts (24.0%), and 244 patients (76.0%) replied that they felt uncomfortable because of this disorder. Nineteen patients (8.6%) with striae distensae had gone through treatment. Among them, 11 (5.0%) had technical treatment in dermatologic clinics such as, pulse dye laser, fractional laser, and chemical peeling. Eight patients (3.7%) were treated with folk remedies including moxibustion and acupuncture therapy. However, 154 patients (71%) responded that they wanted treatment for the striae lesion, and 93 patients (43%) have great intention to treatment. Conclusion: A lot of patients are still suffering from striae distensae, but so far there is no appropriate treatment. The biggest problem is that there is very little understanding of striae distensae. Patients should be aware of their striae distensae and we should provide appropriate treatment. (Korean J Dermatol 2011;49(9):780~785)

Diclofenac 주사 후 발생한 Nicolau 증후군

고재완 ( Jae Wan Go ),김신한 ( Shin Han Kim ),노병인 ( Byung In Ro ),오화은 ( Hwa Eun Oh ),조한경 ( Han Kyoung Cho ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.9

Nicolau syndrome or embolia cutis medicamentosa is a rare complication of a still largely unidentified pathogenesis at the site of intramuscular injections of various drugs. It is characterized by development of an acute, severe pain around the injection site followed by a localized erythema, a reticular rash, a hemorrhagic patch and varying degrees of tissue damage. The disease outcomes vary from atrophic ulcers and pigmentation to lower limb paralysis and limb amputation. We describe a 34-year-old woman with the diagnosis of this syndrome after she received an intramuscular diclofenac-beta-dimethyl-aminoethanol injection to the lateral aspect of the right upper buttock. The patient was treated by surgical debridement with concomitant primary closure. (Korean J Dermatol 2010;48(9):786~789)

정수용 세라믹 분리막의 국산화 기술개발 1

강태구 ( Tae Gu Kang ),김신한 ( Shin Han Kim ),이성우 ( Sung Woo Lee ) 한국공업화학회 2009 응용화학 Vol.13 No.2

Rietveld 정밀화법과 SEM-EDS 분석에 의한 DPF용 코디어라이트 하니컴 세라믹스의 결정성장 과정 분석

채기웅,김강산,김정석,김신한,Chae, Ki-Woong,Kim, Kang San,Kim, Jeong Seog,Kim, Shin-Han 한국결정성장학회 2021 한국결정성장학회지 Vol.31 No.3

코디어라이트(Mg₂Al₄Si₅O₁₈) 하니컴 세라믹스의 대표적 응용분야는 자동차 배기가스 정화용 필터(diesel particulate filter(DPF))이다. 천연광물, 조공제, 유기바인더를 혼합한 슬러리를 압출하여 DPF용 하니컴 코디어라이트를 성형한 후 980~1450℃ 범위에서 소결하였다. 소결온도에 따른 결정상(indialite, cordierite, cristobalite, alumina, spinel, mullite, pro-enstatite)의 형성과정을 XRD Rietveld 정밀화법을 이용하여 정량분석 하였다. 동시에, 세라믹 에칭(etching) 방법으로 소결 시료 표면의 비정질상을 제거한 후 SEM/EDS법을 사용하여 결정상들의 형상과 조성을 확인하였다. 이들 결과로부터 DPF 하니컴에서 결정상 형성 과정을 명확히 밝힐 수 있었다. 또한, DPF 하니컴의 소결온도에 따른 열팽창계수(linear coefficient of thermal expansion, CTE) 변화를 분석하였고, 결정상의 정량분석결과를 바탕으로 계산된 CTE와 비교하였다. 소결된 DPF 하니컴 내의 결정상들이 CTE 특성에 미치는 영향을 고찰하였다. Diesel particulate filter (DPF) is a typical application field of cordierite (Mg₂Al₄Si₅O₁₈) honeycomb. Green body for DPF honeycomb was extruded using slurry paste and sintered at the temperature range of 980~1450℃. Quantitative crystal phase analysis was carried out by using Rietveld refinement method for powder XRD data. In conjunction with the quantitative Rietveld analysis, SEM-EDS analysis was carried for the crystal phases (indialite, cordierite, cristobalite, alumina, spinel, mullite, pro-enstatite). After removing amorphous phase on the sintered surfaces by chemical etching method, the shape and composition of the crystal phases can be clearly identified by SEM-EDS method. By combining the Rietveld refinement method and SEM-EDS analysis, crystal phase evolution process in DPF cordierite ceramics could be clarified. In addition, the coefficient of thermal expansion (CTE) of the DPF honeycombs were measured and compared with the calculated CTEs based on the quantitative crystal phase analysis results.

얼굴에 피부전이를 보인 심장의 혈관육종

고재완 ( Jae Wan Go ),김신한 ( Shin Han Kim ),이상윤 ( Sang Yoon Lee ),노병인 ( Byung In Ro ),조한경 ( Han Kyoung Cho ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.2

Angiosarcoma is a rare, aggressive vascular neoplasm of the endothelial cell origin. It is usually seen in male, elderly patients and generally has a poor prognosis due to its high potential for metastasis. They arise at various sites such as skin, soft tissue, heart and great vessels. However, the tumors have a predilection for skin and superficial soft tissue. Most angiosarcomas of the skin arise in the three clinical variant; primary angiosarcoma of the face and scalp in the elderly patients; following lymphedema, and post radiation or trauma. Although, this tumor tend to recur locally and metastasize to the viscera, especially in the lung, but cutaneous metastasis of angiosarcomas from the internal organ are uncommon. Herein, we report a patient with cutaneous metastasis from primary cardiac angiosarcoma in the right atrium. (Korean J Dermatol 2012;50(2):130~133)

림프종양 구진증과 연속선상으로 발생한 CD30 양성 원발성 피부 이형성 대세포 림프종

고재완 ( Jae Wan Go ),김신한 ( Shin Han Kim ),이상엽 ( Sang Yeop Yi ),조한경 ( Han Kyoung Cho ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.12

Lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large cell lymphoma (ALCL) are grouped under the category of cutaneous T-cell lymphomas as CD30+ lymphoproliferative disorders. Though LyP is clinically characterized by chronic recurrent papulonodular cutaneous lesions, it shows malignant features on the histologic findings. LyP is associated with lymphomas, including primary cutaneous ALCL, mycosis fungoides and other lymphoproliferative disorders. A few cases of LyP related to ALCL have been reported in Korea. We report here on an interesting case of primary cutaneous ALCL that developed in succession after LyP in a 38-year-old female. (Korean J Dermatol 2010;48(12):1081∼1085)

손샅에 거울상으로 발생한 보통사마귀

고재완 ( Jae Wan Go ),김신한 ( Shin Han Kim ),조한경 ( Han Kyoung Cho ) 대한피부과학회 2010 大韓皮膚科學會誌 Vol.48 No.9

Common warts are small, benign tumors, and they are usually self limiting hyperkeratotic skin lesions that are infected by human papillomavirus (HPV). Although warts can occur at any age, they are most often seen in children and young adults. It is most commonly found on the acral skin of the hands and fingers, but the lesions may occur anywhere on the skin surface. There are some cases with uncommon forms for the shape and distribution, but there have been no reported cases of common warts occurring on the finger web in a mirror image form in Korea. Herein, we report on an interesting case of common warts that occurred on the right 4th finger web in a mirror image form in a 3-year-old Korean boy. (Korean J Dermatol 2010;48(9):807~809)

5년간 경험한 사마귀 환자의 임상적 고찰(2007∼2011)

이상윤 ( Sang Yoon Lee ),김신한 ( Shin Han Kim ),손현옥 ( Hyun Ok Son ),천신욱 ( Sin Wook Chun ),송재석 ( Jae Seok Song ),조한경 ( Han Kyoung Cho ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.8

Background: Viral warts are common viral infections and are usually self-limiting. However, there have been few studies assessing the characteristics of patients with viral warts. Objective: The purpose of this study was to assess the epidemiological and clinical characteristics of viral warts during a five-year-period. Methods: We carried out a retrospective analysis of patients with viral warts who had been diagnosed in the Myongji hospital from January 2007 to December 2011. Results: One thousand seven hundred and ninety patients with viral warts were assessed. A group of patients aged under 10 years had the highest occurrence of common warts (46.8%). The mean age was 16.9 years. Hands (47.7%) were more commonly involved than feet (36.4%). Cryotherapy was used to treat most of the patients. One thousand and sixty-one patients (59.3%) showed complete resolution of the wart lesion in the clinical ground. Conclusion: The number of patients with viral warts is currently increasing. This study provides useful data on the prevalence and characteristics of viral warts. (Korean J Dermatol 2013;51(8):593∼599)

Methoxy Polyethylene Glycol-Epoetin Beta에 의해 유발된 백혈구파쇄성 혈관염

이상윤 ( Sang Yoon Lee ),고재완 ( Jae Wan Go ),김신한 ( Shin Han Kim ),손현옥 ( Hyun Ok Son ),조한경 ( Han Kyoung Cho ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.1

Methoxy polyethylene glycol-epoetin beta (Mircera(R), Roche), a third-generation erythropoiesis-stimulating agent (ESA) is known as a continuous erythropoietin receptor activator (CERA). In patients with anemia associated with chronic kidney disease (CKD), it is administered intravenously or subcutaneously. Treatment-related adverse events induced by methoxy polyethylene glycol-epoetin beta occurred in 6%. Hypertension, diarrhea and nasopharyngitis were the most commonly reported adverse events. Cutaneous adverse reactions are rarely experienced with methoxy polyethylene glycol-epoetin beta including maculopapular eruption, facial erythema, and tinea pedis. To the best of our knowledge, no cases of leukocytoclastic vasculitis associated with methoxy polyethylene glycol-epoetin beta have ever been published in medical literature. Herein, we report on a case of leukocytoclastic vasulitis induced by methoxy polyethylene glycol-epoetin beta in a patient with anemia associated with chronic kidney disease. (Korean J Dermatol 2013;51(1):49∼52)