헤모필루스 인플루엔자 기관염이 확인되면서 진단된 혈관륜 1례

김수현,정윤숙,오성희,김남수,김혁,Kim, Su Hyun,Chung, Yoon Sook,Oh, Sung Hee,Kim, Nam Su,Kim, Hyuck 대한소아청소년과학회 2002 Clinical and Experimental Pediatrics (CEP) Vol.45 No.2

저자들은 출생 후 호흡기 증상이 지속되어 오던 여아가 respiratory syncytial virus와 b형 헤모필루스 인플루엔자균에 의한 하기도 감염에 이환되면서 생후 4개월에 혈관륜으로 진단된 1예를 보고하는 바이다. 환아는 출생 후 협착음과 천명음 등의 잦은 호흡기 증상을 보였고, 3개월에 호흡 곤란을 주소로 입원하였으며 respiratory syncytial virus에 의한 세기관지염으로 치료받고 호전되었다. 퇴원 후 증상이 다시 악화되어 재입원 하였으며 b형 헤모필루스 인플루엔자균에 의한 기관염 및 폐렴이 확인되었고, 치료를 위해 기관내 튜브에 도관 삽입을 시도하였을 때 하부 기도에서 저항감이 감지되어 기도 부위의 해부학적 기형을 의심하게 되었다. 3차원 흉부 단층 촬영에서 이중 대동맥궁으로 인한 혈관륜이 확인되었고, 교정 수술을 시행한 후 좋은 경과를 보이고 있다. Vascular ring, originating from abnormal regression of the aortic arch during fetal life, can cause prolonged and recurrent respiratory symptoms and dysphagia when the diagnosis is delayed. We report a 4 month old girl with vascular ring, who had been treated for persistent respiratory symptoms including stridor, wheezing, and dyspnea soon after birth. Initially her respiratory symptoms were thought to be due to bronchiolitis, for which respiratory syncytial virus was confirmed by immunofluorescent staining. Her clinical course was again complicated with tracheitis and pneumonia due to Haemophilus influenzae type b. The possibility of anatomical anomaly was investigated when it was felt to be difficult to insert a suction catheter deep down through a endotracheal tube which was placed for adequate ventilatory management. A three-dimensional chest CT revealed a vascular ring consisting of a double aortic arch. For 5 months following surgery, her respiratory symptoms have slowly been improving. She developed another episode of pneumonia which was milder than the one which occurred before the surgery.

새로운 n형 고분자인 DFPP 기반의 MEH-PPV/DFPP Blend 소자의 광전특성

김수현,문지선,이재우,이석,김선호,변영태,김동영,이창진,김유진,정영철,이긍원,Kim, Su-Hyun,Moon, Ji-Sun,Lee, Jae-Woo,Lee, Seok,Kim, Sun-Ho,Byun, Young-Tae,Kim, Dong-Young,Lee, Chang-Jin,Kim, Eu-Gene,Chung, Young-Chul,Rie, Kung-Won 한국광학회 2006 한국광학회지 Vol.17 No.5

Optical characteristics in polymer films of MEH-PPV/DFPP blends were for the first time investigated. DFPP (N, N'-diperfluorophenyl-3,4,9,10-perylenetetracarboxylic diimide) used here was a novel n-type polymer, which had good stability in air and solubility in common solvents. For a 1:9 DFPP:MEH-PPV blend, highly efficient quenching of photoluminescence (PL) was observed. In addition, the photocurrent responses of these MEH-PPV/DFPP photovoltaic cells were measured. When the light intensity was $50mW/cm^2$, short-circuit photocurrent densities were two times higher than those of single layer MEH-PPV devices. MEH-PPV/DFPP 혼합물의 고분자 박막에서 광학적 특성들이 최초로 조사되었다. 여기서 사용된 BFPP(N, N'-diperfluorophenyl-3,4,9,10-perylenetetracarboxylic diimide)는 새로운 n형 고분자인데 공기 중에서 안정성이 우수하고 일반 용매에서 잘 용해되었다. 1:19 DFPP:MEH-PPV 혼합물의 경우 매우 효율적인 형광소멸이 관측되었다. 더불어 이 MEH-PPV/DFPP 광전 셀의 광전류 응답특성들이 측정되었다. 빛의 세기가 $50mW/cm^2$일 때 단락전류 밀도는 단일 층의 MEH-PPV 소자들보다 2배 이상 되었다.

고지방식이로 비만을 유도한 C57BL/6 마우스에서 SM17의 항산화 및 항비만 효과

김수현,김수지,김경조,이아름,노성수,이영철,Kim, Soo Hyun,Kim, Su Ji,Kim, Kyeong Jo,Lee, Ah Reum,Roh, Seong-Soo,Lee, Young Cheol 대한본초학회 2017 大韓本草學會誌 Vol.32 No.5

Objectives : Obesity is caused by the excess accumulation of fat in the body due to energy imbalance, and it causes various diseases. The aim of this study was to investigate an anti-obesity efficacy and an antioxidant activity of water from herbal mixture extract (SM17). Methods : The antioxidant activities were evaluated through radical scavenging assays using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radicals. To evaluated anti-obesity effect of SM17, we used a high fat diet fed mouse model. The SM17 (150 mg/kg body weight/day, p.o.) was treated every day for 6 weeks to C57BL/6 mice. Body weight and food intake were measured every day. The changes of reactive oxygen species (ROS), alanine aminotransferanse (ALT), aspartate aminotransferase (AST), triglycerids (TG) and total cholesterol (TC) in serum were analyzed after experiment. Also, expression of lipid metabolism related proteins were investigated by western blot analysis. Results : It was effective in antioxidant measurements, SM17 administration inhibited the biomarkers of lipid metaboism in serum and tissues. The administration of SM17 showed a significant reduction of body and tissue weight. Morever, it decreased ROS, ALT, AST, TG and TC in serum, compared with those of the obese mice. Adipogenesis-related protein expressions increased in obese mice compared to normal mice. However, SM17 group exhibited the down-expression of these proteins. Conclusion : A SM17 aqueous extract has a great effect on the stimulation (AMPK) activation, and may have a benefit to reduce a fatty acid metabolism through inhibition of lipid accumulation.

암 환자와 건강인의 심박변이도 및 맥파 특징 비교

김수현,염지윤,오승윤,박수정,Kim, Su-Hyun,Yeum, Ji-Yoon,Oh, Seung-Yun,Park, Soo-Jung 대한암한의학회 2021 大韓癌韓醫學會誌 Vol.26 No.1

Objectives: The purpose of this study is to examine whether heart rate variability (HRV) and pulse wave of cancer patients can be used as indicators of their health status and prognosis. Methods: We retrospectively compared HRV, pulse wave and body mass index (BMI) of cancer patients and healthy individuals who visited W hospital from November of 2020 to October of 2021. Results: As a result of comparing HRV and pulse wave parameters between cancer patients and healthy subjects, among HRV indices, mean heart rate (MHR), standard deviation of normal to normal (SDNN) and total power (TP), very low frequency (VLF) showed significant differences between two groups. Cancer patients' pulse wave parameters showed more rapid and superficial than that of healthy subjects. Also, cancer patients weighed less and had lower BMI. Conclusion: For increased MHR, decreased SDNN, rapid and superficial pulse wave can be indicators of poor prognosis of cancer patients, keep monitoring HRV and pulse wave can help to manage patients efficiently.

Cloud 서버를 포함한 EPC 망에서 WLAN 오프로딩 경로 선택

김수현,민상원,Kim, Su-Hyun,Min, Sang-Won 한국정보통신학회 2013 한국정보통신학회논문지 Vol.17 No.11

There coexist various access network for mobile terminals, such as mobile phones, smart phones, and tablet PC, in mobile and wireless network. In these circumstance, the network traffic overload unexpected causes the service degradation or discontinuity. To solve this problem, we consider a off-loading route selection by a cloud server which monitors traffic volume and selects an appropriate route. With our proposed scheme, it is possible for the EPC network with untrusted WLAN access networks to operate efficiently to a trusted service level. Also, an optimal handover with satisfying service requirements could be achieved by the proposed offload scheme. 스마트 폰, 태블릿 PC와 같은 이동단말기와 다양한 무선통신 기술의 발전으로 차세대 이동통신망은 다양한 액세스 네트워크들이 공존한다. 다양한 네트워크에서의 서비스 연속성 및 네트워크 상황에 따른 서비스 품질 저하, 그리고 EPC 망의 트래픽 과부하 현상은 여전히 문제로 남아있다. 본 논문에서는 EPC 망에서 과부화 되는 트래픽을 클라우드 서버로 분산하여 선택하는 기법을 제안한다. 제안한 방안을 통해 신뢰할 수 없는 WLAN 액세스 네트워크와 EPC 네트워크에서 효율적인 최상의 핸드오버 방안을 제공할 수 있으며 사용자에게는 네트워크 상황에 따른 최적의 서비스를 제공할 수 있다.

임플란트 일차 안정성에 있어서 고정체 지름에 따른 osteotome 술식의 효과

김수현,이재관,박찬진,Kim, Su-Hyun,Lee, Jae-Kwan,Park, Chan-Jin 대한치주과학회 2005 Journal of Periodontal & Implant Science Vol.35 No.3

Primary stability is a fundamental criteria of implant success. There has been various trials to increase initial stability and bone to implant contact. The objective of osteotome technique is to preserve all the existing bone by minimizing or even eliminating the drilling sequence of the surgical protocol. The bone layer adjacent to the osteotomy site is progressively compacted with various bone condensers(osteotomes) this will result in a denser bone to implant contact. This improved bone density helps to optimize primary implant stability in low density bone. The use of wide implant is one of methods to increse primary stability. They can be used in special situations in which they can increase the surface area available for implant anchorage and improve their primary stability The aim of this study was to evaluate the influence of the osteotome technique and implant width on primary stability. Osteotome technique was compared with conventional drilling method by resonance frequency measurments according to the implant fixtures diameter. The results were as follows: 1. The average of ISQ value was sightly higher in osteotome technique, but there was not statistically significant in regular and narrow implant(p <0.05). 2. Either osteotome technique or conventional technique. ISQ value was significantly higer as increasing of implant diameter(p <0.05). 3. ISQ value of drilling technique was higer than those of osteotome technique in wide implant. It was assumed to be caused by difference in final preparation diameter.

의사를 위한 호스피스 교육 프로그램의 개발 - 2004 호스피스.완화의료 시범사업을 중심으로 -

김수현,신상원,정미경,이순남,이소우,이경식,최윤선,Kim, Su-Hyun,Shin, Sang-Won,Chong, Mi-Kyong,Lee, Soon-Nam,Lee, So-Woo,Lee, Kyung-Shik,Choi, Youn-Seon 한국호스피스완화의료학회 2006 한국호스피스.완화의료학회지 Vol.9 No.2

목적: 2004년 호스피스 완화의료 시범사업을 실시하면서 의사를 대상으로 한 사업을 위하여 호스피스 완화의료에 관한 교육 프로그램을 개발하고 이를 기초로 교육을 실시하고 성과를 분석하였다. 방법: 교육 분과위원회에서 3차례의 회의를 통해 교육 요구도(총 79문항) 설문지를 개발한 후 125개 전국 호스피스 관련 기관에 종사하는 의사를 대상으로 우편을 이용하여 설문지를 발송하였다. 교육 중요도는 호스피스 전문가 27명에게 이메일을 통하여 조사하였다. 결과: 교육 요구도 및 중요도 조사 결과, 다양한 문헌 검토 및 외국의 호스피스 완화의료 관련 교육과정을 기초로 호스피스 완화의료 교육 프로그램이 개발되었으며 교육 시간은 총 36시간(이론 21, 실습 15시간)이었다. 이를 토대로 1일 교육 코스를 전국에서 4회에 걸쳐 시행하였으며 47명의 의사가 참여하였다. 교육 이수 후 참가자들은 교육 과정이 향후 업무에 도움이 된 정도는 항목마다 $3.0{\sim}3.6$점, 교과 강사의 적절성은 $3.1{\sim}3.3$점으로 평가하였다(1: 전혀 아니다 ${\sim}4$: 매우 그렇다). 전반적인 만족도는 100점 중 80점이었다. 결론: 개발된 교육 프로그램은 전체적으로는 운영되지 않았으며 일부만 시험교육으로 운영하였다. 대상자들은 대체로 만족하였으나 강의보다는 사례, 토론 중심의 교육 및 주제별 심화교육을 원하였다. 향후 지속적인 요구도 조사와 프로그램 개발 및 시행이 필요하다. Purpose: The purpose of this study was to develop education program for physicians who work at hospice palliative care settings in Korea, to practice abridged education program extracted from the full contents of the proposed education, and to improve the quality of hospice palliative care service. Methods: To develop the education program, questionnaire for hospice education need assessment (total 79 items) was distributed to 125 organizations practicing hospice service via mail and the data was collected from 1 Sep. to 10 Oct. 2004. Another questionnaire for hospice education importance assessment was asked to the palliative specialists from Sep. 23 to 17 Oct. 2004. Based on the analysis of the questionnaires, and reviewing various references and actual hospice palliative education programs of other countries, the education programs were developed. Results: Ore-day-Hospice education 2004 was conducted based on the suggested education program, and it was practiced four times on a national basis (2 times in Seoul, and once in Busan and Gwangju, respectively). 47 physicians attended the education program. The education program lasted about 7 hours, comprising 5 hours of common lectures for all attendants regardless of their professions and 2 hours of specific seminar for physicians only. Attendants positively responded to the contents of the education program. But they pointed out that the program should be offered on weekday and it should be more in-depth and more discussion based lesson. Conclusion: The suggested education program was not fully conducted yet. After practicing the abridged education program, more in-depth and discussion oriented rather than lecture-based education were suggested. It may be argued that the proposed education, which requires much longer period education, should also reflect the evaluation of the 1-day education program to successfully implement the proposed education program.

예고된 단일 광자 광원을 이용한 레겟-가르그 부등식 모사

김수현,문한섭,Kim, Su Hyun,Moon, Han Seb 한국광학회 2021 한국광학회지 Vol.32 No.1

본 논문에서는 주기적 분극된 비선형 결정(periodically poled potassium titanyl phosphate; PPKTP)에서 자발매개하향변환(spontaneous parametric down conversion; SPDC)과정으로 생성된 예고된 단일 광자 광원을 이용하여 레겟-가르그 부등식(Leggett-Garg inequality; LGI)의 위배를 실험적으로 모사하였다. 생성된 광자의 편광 방향에 따라서 편광된 광자 수를 측정하여 n-측정수에 따른 레겟-가르그 부등식을 모사하였다. 단일 광자의 편광 기반 LGI에 대한 실험 결과는 이론적인 계산 결과와 일치하는 것을 확인하였다. We have experimentally simulated the violation of the Leggett-Garg inequality (LGI) using a heralded-single-photon source via spontaneous parametric down-conversion (SPDC) in a periodically poled potassium titanyl phosphate (PPKTP) crystal. We measured the polarization fringe as a function of the angle of the linear polarization of the photons, and analyzed the LGI according to n measurement. Simulation results for LGI based on the polarization of the heralded single photon were in good agreement with theoretical calculations.

SSGDBR 레이저 다이오드의 파장변환 특성 해석

김수현,정영철,Kim, Su-Hyun,Chung, Young-Chul 대한전자공학회 1999 電子工學會論文誌, D Vol.d36 No.2

다양한 파장변화 기술중에서 레이져 다이오드의 발전상태에서 교차이득변도(Cross-Gain Modulation)을 이용한 파장변환은 고속의 신호를 매우 간단하고 효율적으로 처리할 수 있다. 본 논문에서는 SSGDBR (Superstructure Grating Distributed Bragg Reflector) 레이저 다이오드의 파장변환기로서 특성을 분석하고 광통신 네트웍 모델링을 위한 CAD 도구로서 개선된 시영역 대신호 동적모델(Time-Domain Large-Signal Dynamic Model)의 유용성을 제시하였다. 이 모델을 l용하여 이런 구조의 파장변환 소자는 10Gbps이상 고속데이터를 처리할 수 있고 광대역 파장변환이 가능하다는 것을 확인하였다. 입력 광신호의 세기와 주입되는 전류가 파장변환된 신호의 소광비 등에 미치는 영향 및 Eye Diagram 등을 살펴 보았으며, 기존에 발표된 실험결과들과 매우 유사한 경향을 보임을 관측하였다. Among various wavelength conversion technologies, that using the cross-gain modulation in laser diode makes it possible to deal with the high speed signal quite simply and efficiently. In this paper, presented was the applicability of an improved time-domain large-signal dynamic model as a CAD tool to analyzed the characteristics of SSGDBR(Superstructure Grating Distributed Bragg Reflector) laser diodes used for wavelength converters. Using this model, it was shown that this kind of wavelength converter can provide the widely tunable wavelength conversion of the high speed data above 10 Gbps. We also investigated the effect of input optical power and the bias current on the characteristics of the device such as extinction ration and eye diagram. The modeling results show very similar trend to the experimental reports.

녹용대보탕을 투여한 ITP 의증 환자 증례보고

김수현,서인교,정혜인,김준형,전상우,안수빈,강세영,Kim, Soo-hyun,Seo, In-kyo,Jeong, Hye-in,Kim, Jun-hyung,Jeon, Sang-woo,Ahn, Su-bin,Kang, Sei-young 대한한방내과학회 2021 大韓韓方內科學會誌 Vol.42 No.5

Objectives: This study demonstrated the positive effect of herbal medication on a suspected idiopathic thrombocytopenic purpura (ITP) patient-a 57-year-old male with suspected ITP and a decreased platelet count. Methods: The patient was treated with an herbal medicine named Nokyongdaebo-tang, and its effect was measured with periodic platelet blood tests. Results: Before taking the herbal medicine, the patient's blood platelet count was 98 K/μl, but following treatment, the blood platelet count increased to 201 K/μl and maintained a continuously elevated level. Conclusion: The results indicated that herbal medication may improve the blood platelet count of suspected ITP patients.