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      • SCIESCOPUSKCI등재

        Dihydropyridine Dinucleotide ( NADH ) 와 탈수소 효소의 결합 반응에 관한 연구

        김수자,이현재 ( Soo Ja Kim,Hyun Jae Lee ) 생화학분자생물학회 1976 BMB Reports Vol.9 No.1

        The L-α-glycerophosphate dehydrogenase-catalyzed reduction of dihydroxyacetone phosphate was studied to investigate the properties of NADHdehydrogenase complex. A series of oxidized coenzyme (NAD) competitive inhibitors were employed for the study of inhibition on the reverse reaction of NAD-linked dehydrogenase systems. Inhibition by adenosine derivatives and carboxylic acids was competitive with respect to NADH, and by N¹-alkylnicotinamide chlorides and n-alkyl-ammonium chlorides was non-competitive with respect to the reduced coenzyme. The dihydronicotinamide ring of NADH was demonstrated not to interact with the pyridinium ring region, but was proposed to interact with the hydrophobic region instead.

      • SCOPUSKCI등재

        Inactivation Study of Pyridine-Linked Dehydrogenases by $N^1$-Alkylnicotinamide Chlorides

        김수자,이현재,Kim Soo-Ja,Lee Hyun Jae Korean Chemical Society 1976 대한화학회지 Vol.20 No.5

        A series of $N^1$-alkylnicotinamide chlorides, $N^1$-methyl-to $N^1$-dodecylnicotinamides inclusive were studied with rabbit muscle L-${\alpha}$-glycerophosphate dehydrogenase to investigate the possibility of reversible and irreversible inactivation of the pyridine-linked dehydrogenases by the coenzyme-competitive inhibitor derivatives. The inhibition of the enzyme by $N^1$-alkylnicotinamide chlorides was demonstrated to be reversible at the dilute concentration of the inhibitors but this reversible inhibition was found to be followed by an irreversible time-dependent inactivation measuable at high concentrations of the inhibitors. The properties of this time-dependent inactivation were discussed on the basis of the denaturation of the enzyme by the binding of small micelle-like structures formed at higher concentrations of the inhibitors. Pyridine관여 탈수소 효소는 $N^1$-alkylnicotinamide chloride 유도체에 의하여 저해 작용을 받고 있는 바 저해제이 농도 변화에 따른 효소 저해작용이 가역 또는 비가역 불활성화 반응에 기인하는지의 여부를 밝혀 보기 위하여 토끼 근육으로 부터 유리한 L-${\alpha}$-glycerophosphate dehydrogenase를 사용하여 연구하였다. 이 효소의 저해작용은 상용한 저해제 유도체의 농도가 희박했을 경우 가역적인 효소저해 반응을 보여주고 있으나 저해제의 농도가 증가함에 따라 점차 비가역적인 효소 불활성화로서 나타남을 알았으며 이러한 비가역 불활성화 반응은 저해제의 농도가 증가함에 따라 형성될 수 있는 micelle 구조의 미세분자와의 결합에 의한 효소의 변성에 기인할 것이라고 결론을 얻었다.

      • KCI등재

        논문 : 재한일본인처의 경계인으로서의 삶과 기억의 재구성

        김수자 ( Soo Ja Kim ) 이화사학연구소 2013 梨花史學硏究 Vol.0 No.46

        This study focused on reconstructing lives of Japanese wives, who have lived as boundary people in Korea through their “oral messages.” Based on the data of oral communication, this study selected direct delivery method conveying messages by their own words. In history, Japanese Wives in Korea can be classified by three major types. As the first Japanese wives type, they got married Korean people during Japanese colonial era in Japan, came to Korea around 1945 and they were the main portion of Japanese wives. Second, Japanese wives had come to Korea before 1945, and married Korean staying at continuously. At last, Japanese women in Manchuria of China were united Korean husband on returning progress to Mother land by defeat of Japan in Second World War and they remained in Korea. In 1945 Japanese losing on war, Japanese Wives in Korea had come to husbands` home town with their man in spite of their family and relatives` opposition. They have said their Korean life was a hard and tough journey from that moment. When they had come to Korea from Japan, they feared about coming to an undeveloped country. They had difficulties in accepting and adapting to Korean obsolete culture and habit on their sights. Especially on language, toilet, bathing, foods, and other general life style, they couldn`t understand the Korean things which were mysterious to them. By tension on the blockage of communication with fear and horror at the strange country, the Japanese wives have severely cowered on their mind. On suspense and psychologically shrinkage mind, they couldn`t have easily accepted or allowed Korean cultures. On a strange Korean life, there was one more difficulty to Japanese wives caused by their husband`s attitudes different from Japan. Korean husbands, in a few days after arriving in Korea, had beaten their Japanese wives and tortured their wives on physically and mentally. After colonial era, Korean had have negative images on Japan all over the society. Although Japanese wives have accepted Korean`s anti-Japanese sentiment of Korean people, “which could be occurred on colonial Korean people,” they have hurted on their self-esteem by continuous disdain and contempt of korean people toward Japanese. Until nowadays, Japanese wives live in Korea as boundary people, who is neither Japanese nor Korean. They have lived together with Korean about 70 years while experiencing political and economical rise and fall at Korean contemporary history. Although they have companied with Korean people on uneven historical situation, they have suffered on getting Korean citizenship and still recognized as a marginal citizen.

      • KCI등재후보

        연구논문 : 한국형 도형심리유형과 사상체질의 상관관계 연구

        김수자 ( Soo Ja Kim ),윤천성 ( Chun Sung Youn ) 아시아문화학술원 2015 인문사회 21 Vol.6 No.2

        본 연구는 한국형 도형심리유형 검사로 성격유형을 탐색하고, 이를 바탕으로 성격유형과 사상체질 간에 어떠한 상관관계가 있는지를 분석하였다. 이를 통해 개인의 내적요인인 성격이 체질적 특성과는 어떠한 관계가 있는지를 체계적으로 탐색하였다는데 의의가 있다. 본 연구의 주요점은 다음과 같다. 첫째, 한국형 도형심리유형 검사를 통해 빈도분석을 실시한 결과,``동그라미``124명(54.4%)으로 가장 높게 나타났고,``네모``47명 (20.6%),``에스``43명(18.9%),``세모``14명(6.1%) 순으로 나타나 대체적으로 동그라미 유형이 많은 것으로 나타났다. 둘째, 사상체질 검사를 통한 빈도분석 결과``소음인``이 148명(64.9%)으로 가장 높게 나타났고,``소양인``62명(27.2%),``태음인``18명(7.9%) 순으로 나타나 대체적으로 소음인이 많은 것으로 나타났다. 셋째, 한국형 도형심리유형에 따른 사상체질 유형별 차이가 있는지 검증한 결과, 통계적으로 유의미한 차이가 나타났으며 (p<.01), 동그라미, 네모, 에스 유형의 경우 60% 이상이 소음인인 것으로 나타났으나 세모유형의 경우 50.0% 이상이 소양인인 것으로 나타나 차이를 보였다. 한국형 도형심리유형과 사상체질과의 상관관계에서 뚜렷한 일관성은 없으나, 앞으로 더 많은 표본을 대상으로 연구를 진행한다면 성격적 특성과 체질과의 연관성을 통해 인간관계를 하는데 많은 도움을 줄 것이다. This study explored personality type using the Korean Geometry Psychology Type Indicator, and based on the results, analyzed the correlation between personality type and Sasang constitution. This study is meaningful in that it explored systematically how personality, an individual``s internal factor, is related to the person``s constitutional characteristic. The major findings of this study are as follows. First, according to the results of frequency analysis using the Korean Geometry Psychology Type Test, 124 (54.4%) of the subjects were found to be of``circle``type, 47(20.6%) of``square,``43 (18.9%) of``S,``and 14 (6.1%) of``triangle,``so the circle typewas most frequent. Second, according to the results of frequency analysis through Sasang constitution test, 148 (64.9%) of the subjects were ``Soeumin,``62 (27.2%)``Soyangin,``and 18 (7.9%)``Taeeumin,``so Soeumin was most frequent. Third, according to the results of testing differences in Sasang constitution type according to Korean Geometry Psychology Type, statistically significant differences were observed (p<.01). That is, over 60% of those of circle, square, or S type were Soeumin, and over 50% of those of triangle type were Soyangin. No noticeable consistent correlation was observed between Korean Geometry Psychology Type and Sasang constitution, but further research with a larger sample is expected to be helpful in guiding human relationships based on the association between personality characteristic and constitution.

      • KCI등재
      • KCI등재
      • KCI등재
      • KCI등재
      • KCI등재

        한국형 도형심리 양육태도 척도 개발 타당성 연구

        김수자 ( Soo Ja Kim ),윤천성 ( Chun Sung Youn ),김재진 ( Jae Jin Kim ) 아시아문화학술원 2015 인문사회 21 Vol.6 No.4

        본 연구는 한국형 도형심리 양육태도 척도 개발을 위한 타당도를 검증하는 데 있다. 한국형 도형심리 양육태도 척도는 동그라미, 에스, 세모, 네모 유형의 네 가지 요인으로 이루어져 있다. 이러한 연구를 위하여 문헌 고찰과 선행 연구자들의 연구논문, 경험적 자료와 전문가들의 의견 조사를 통해 개념을 정하였으며, 설문조사를 통해 타당성 검증 과정을 거쳤다. 문항 선정 과정에서는 1차로 문헌 조사와 함께 전문가(박사 4명)들이 토의를 거쳐, 문항 교정의 과정을 거쳤으며, 교정과정에서 바람직하지 않은 문항을 제거 및 수정을 하였으며, 2차에서는 대전·경남 지역에서 아동을 양육해본 경험이 있는 어린이집 종사자 60명을 대상으로 검사와 워크샾을 실시, 4개 요인 총 100문항(각 25문항)의 척도 시안을 추출해냈다. 3차에서는 대전·충청·경남·전북·경기 지역의의 성인 222명을 대상으로 구성된 척도에 대한 설문조사를 실시하였다. 4차 에서는 문항 전체에 대한 요인 분석과 신뢰도 검증, 상관관계 분석 등을 통하여 총 52개(각 13개) 문항으로 압축된 최종 척도를 개발하였다. 본 연구 결과의 주요점은 다음과 같다. 첫째, 본 연구에서 개발한 척도는 문헌 및 선행 연구자들의 이론적 근거를 바탕으로 워크샾에 참석한 사람들의 경험 등을 함께 수집 분석하여 질문지의 문항들을 제작하였다는 특징이 있다. 둘째, 척도의 문항 선정 과정에서 전문가들과 워크샾에 참석한 사람들의 의견에 대한 내용 타당성 분석을 함께 진행함으로써 실용 가능한 척도를 개발하였다. 셋째. 아동이 성장하할 수 있도록 도움을 줄 것이며, 학교나 가족상담의 영역에서 많은 도움을 줄 것이다. 끝으로 이 분야에 대한 후속 연구에서는 다음 상황들을 참작하여 연구를 진척시켜야 할 것이다. 첫째, 사람의 성격은 전 생애에 걸쳐 발달하는 것이므로 초기 아동기 시기 양육자와의 관계 양식, 사회 속에서의 경험, 소통 등을 고려하여 성장기 아동 및 청소년 특성에 맞는 연구를 확대 개발할 필요가 있다. 둘째, 본 연구의 연구 대상자들이 한정된 인원으로 구성되었으므로 표본을 전국으로 확대시켜 본 척도를 표준화한다면 더욱 더 유용한 도구로 발전할 수 있을 것이다. 셋째, 본 연구에서는 양육자들에 대한 일반적인 성격적 특성만을 알 수 있지만, 후속 연구로 리더십, 인성, 진로 등의 척도가 개발 된다면, 본 척도와 더불어 좋은 도구가 될 것이다. 넷째, 한국형 도형심리유형은 성격을 진단하는 심리 도구로만 그치는 것이 아니라, 앞으로는 기질별 인성개발, 학교적응, 진로탐색프로그램 등과 연계되어 학생들의 진로를 결정하게 도와주고 자기 자신을 건강한 방향으로 안내해야 할 것은 물론 각기 다른 사람들의 다면적 성격 특성에 관한 연구가 진행되어야 할 것이다. The purpose of this study was to test validity for developing a Korean childrearing attitude scale based on geometry psychology. The scale consists of four factors, which are circle, squiggle, triangle, and square. For this study, concepts were defined through literature review and the survey of previous studies, experiential materials, and experts’ opinions. In addition, validity was tested through a questionnaire survey. In the process of item selection, first, the items were corrected through literature review and consultation with experts(four doctors), and undesirable items were removed or revised in the course. Second, a survey and workshop were conducted with 60 employees of childcare centers in Daejeon and Gyeongsangnam-do, who were experienced in child rearing, and a total of 100 items for four factors(25 per factor) were extracted as a draft scale. Third, a questionnaire survey was conducted using the draft scale with 222 adults in Daejeon, Chungcheong-do, Gyeongsangnam-do, Jollabuk-do and Gyeonggi-do. Fourth, factor analysis, reliability test, correlation analysis, etc. were conducted for all the items, and 52 items(13 per factor) were selected as the final scale. The main findings of this study are as follows. First, the scale developed in this study is unique in that the items of the questionnaire were drafted based on theoretical grounds of related literature and previous studies and analysis of workshop participants’ experiences. Second, a practical scale was developed through testing the content validity of experts’ and workshop participants’ opinions in the process of item selection. Third, in the process of children’s growth, caregivers’ desirable child-rearing attitude is expected to contribute to the formation of healthy personality and to promote human relations, and furthermore, it will be greatly helpful in the areas of school, family counseling, etc. Lastly, subsequent research in this area needs to consider situations as follows. Firstly, because one’s personality develops through lifetime, it is necessary to expand the scope of research in consideration of the characteristics of growing children and adolescents such as their relationship style with caregivers, experiences in society, and communication. Secondly, as the subjects of this study were sampled from limited areas, the scale needs to be standardized using an expanded sample representing the whole country. Thirdly, this study focused on caregivers’ personality-related characteristics, but the development of scales on leadership, personality, career, etc. in future studies will be highly useful along with the scale developed in this study. Fourthly, the Korean Geometry Psychology Type needs to be used not only as a psychological tool for diagnosing personality but also as a guidance for students’ career decision and healthy life direction in connection to programs for character development, school adjustment, career exploration, etc., and multi-dimensional research should be made on the personality characteristics of different groups of people.

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