존멜팅법을 이용한 원통형 (YSmNd)-Ba-Cu-O계 초전도체의 결정성장 및 수송 전류 특성

김소정,박종국,Kim, So-Jung,Park, Jong-Kuk 한국결정성장학회 2011 韓國結晶成長學會誌 Vol.21 No.5

$(YSmNd)_{1.8}Ba_{2.4}Cu_{3.4}O_{7-x}$ [(YSN)1.8] high $T_c$ superconductor was directionally grown by zone melt growth process, in air atmosphere. In this study, optimum melting temperature and growth rate were $1100^{\circ}C$ and 3.5 mm/hr, respectively. The microstructure of well-textured (YSN)1.8 samples were examined by XRD, optical microscopy, TEM and SQUID magnetometer. The critical current density of these samples were measured by the direct transporting current method. In the observation using an optical microscopy, nonsuperconducting $(YSmNd)_2BaCuO_5$[(YSN)211] inclusions of (YSN)1.8 superconductor uniformly distributed within the superconducting (YSmNd)$Ba_2Cu_3O_x$[(YSN)123] matrix. The directionally melt-textured (YSN)1.8 superconductor showed an onset $T_c{\geq}90\;K$ and sharp superconducting transition. The transport $J_c$ values were 830 A and $3.93{\times}10^4$ (A/$cm^2$) at 77 K self-field, respectively. 존멜팅법을 이용해서 $(YSmNd)_{1.8}Ba_{2.4}Cu_{3.4}O_{7-x}$계 고온초전도체를 대기 중에서 용융성장실험을 하였다. 존멜팅법의 최적용융온도는 $1100^{\circ}C$였으며 성장속도는 3.5 mm/h 였다. 한 방향으로 용융성장 된 (YSN)1.8 초전도체는 XRD, 광학현미경, TEM을 이용하여 미세구조를 관찰하였으며 SQUID magnetometer와 직접전류수송법을 이용해 초전도특성을 평가하였다. 특히 용융성장 된 (YSN)1.8 초전도체의 광학현미경에 의한 미세구조 관측 결과 초전도상인 (YSN)123 matrix내에 비초전도상인 (YSN)211 inclusions이 균질하게 분포되어 있는 것이 관측되었다. 또한 용융성장 된 (YSN)1.8 초전도체는 90 K 이상의 임계온도 특성을 보였으며 액체질소 안에서 직접전류수송법으로 측정한 결과 수송전류 830 A에서 $3.93{\times}10^4$(A/$cm^2$)를 갖는 높은 임계전류밀도 특성을 보였다.

치성 및 비치성 조직이 악골 창상치유에 미치는 영향에 관한 실험적 연구

김소정,황의환,이상래,홍정표,Kim So-Jung,Hwang Eui-Hwan,Lee Sang-Rae,Hong Jung-Pyo 대한영상치의학회 1996 Imaging Science in Dentistry Vol.26 No.2

This study was for comparing healing patterns and effects between with odontogenic and nonodontogenic tissues on the defected mandible. Experimental bone defects that measured 3 mm in diameter were created on the mandibular body of guinea pig by removal of bone with the use of trephine burs and bone defects were grafted with Biogran(Orthovita Co., U.S.A.) and covered with Dura Mata(Pfrimmer-Viggo GmbH Co., Germany). Guinea pigs were serially terminated by fours on the 3 days, the 1 week, the 2 weeks, the 3 weeks, the 4 weeks, and the 5 weeks after experiment, and the mandibular body was removed and fixed with 10% neutral formalin. They were decalcified and embedded in paraffin as using the usual methods. The specimen sectioned and stained with hematoxylin and eosin and toluidine blue. They were observed with a light microscope and a polarizing microscope. The obtained results were as follows : 1. Defected bone was healed fast from the odontogenic tissues in early stage of the experiment. 2. The arrangement of the bone matrix was relatively regular in the bone from the nonodontogenic tissues, but irregular in the bone from the odontogenic tissues. 3. Compact bone has started to be resorbed and changed to the pattern of matrix bone tissue from 3 weeks after experiment.

존멜팅법으로 제조한 (YNdSm)-Ba-Cu-O계 고온복합초전도체의 미세구조 및 전기적 특성

김소정,이상헌,Kim, So-Jung,Lee, Sang-Heon 한국전기전자재료학회 2016 전기전자재료학회논문지 Vol.29 No.2

(YNdSm)-Ba-Cu-O system high Tc composite superconductors were directionally grown by zone melting process, having large temperature gradient, in air atmosphere. Cylindrical green rods of $(YNdSm)_{1.8}Ba_{2.4}Cu_{3.4}O_x$ [(YNS)1.8]composite oxides by CIP (cold isostatic pressing) method using rubber mold were fabricated. The microstructure and superconducting properties were investigated by XRD, TEM and SQUID magnetometer. The size of nonsuperconducting $(YNdSm)_2BaCuO_5$ inclusions of the melt-textured (YNS)1.8 sample with $CeO_2$ additive were remarkably reduced and uniformly distributed within the superconducting (YNS)1.8 matrix. (YNS)1.8 samples, with / without $CeO_2$ additive, showed an onset $T_c{\geq}90K$ and sharp superconducting transition. The critical current density $J_c$ value of the (YNdSm)1.8 superconductor with $CeO_2$ additive were 840 A, $1.2{\times}104A/cm^2$ in 77 K, 0 Tesla by direct current transport method.

Pretreatment of curcumin protects hippocampal neurons against excitotoxin-induced cell death

김소정,김근호,공경혜,이재원,Kim, So-Jung,Kim, Keun-Ho,Kong, Kyoung-Hye,Lee, Jae-Won Korean Society of Life Science 2007 생명과학회지 Vol.17 No.1

Curcumin은 자연에 존재하는 황색의 페놀성분의 커리 향신료이며 항산화 및 항염증의 성질을 가지고 있어서 산화 스트레스와 면역염증과 관련한 여러 질병의 치료로 사용되어져 왔다. 이러한 curcumin의 항산화 및 항염증 효과는 여러 퇴행성 신경질환으로부터 뇌를 보호하는데 유용하게 적용될 수 있다. 본 연구에서는 glutamate에 의한 excitotoxicity로부터 해마신경세포를 보호하는 curcumin의 신경보호효과에 대하여 보고한다. 태아 생쥐의 해마로부터 얻어진 신경세포를 저농도의 curcumin으로 전처리한 경우, 신경세포는 glutamate에 의한 세포사멸로부터 보호되었다. 그러나 이러한 신경보호효과는 산화스트레스의 조절과는 무관하였다. 흥미롭게도 고농도의 curcumin전처리는 오히려 초대배양 신경세포의 세포사멸을 유도하였다. 해마신경세포에서 스트레스 반응 단백질인 HSP70이 저농도의 curcumin을 처리하였을 때 현저하게 증가하였으며 반면 세포사멸의 마커인 절단된 PARP의 양은 고농도의 curcumin을 처리하였을 때 급증함이 immunoblot분석을 통하여 관찰되었다. 이러한 발견은 curcumin이 excitotoxin인 glutamate에 대한 신경세포의 반응을 조절할 수 있음을 보여주고 curcumin과 관련 화합물들의 퇴행성 신경질환에서의 예방 및 치료법으로의 가능성을 제시하고 있다. Curcumin is a natural phenolic yellow curry spice, derived from the tumeric, which has been used for the treatment of diseases associated with oxidative stress and inflammation. Curcumin is known to have both anti-oxidative and anti-inflammatory properties. These properties can be beneficial to protect the brain from the neurodegenerative diseases. We now report the neuroprotective effects of curcumin pretreatment in primary hippocampal neurons to glutamate-induced excitotoxicity. Pretreatment of embryonic mouse hippocampal cell cultures with low does of curcumin protected neurons against glutamate-induced death, however, this neuroprotection was not correlated with the modulation of oxidative stress. Interestingly, high dose of curcumin showed the cytotoxicity in primary cultured hippocampal neurons. Immunoblot analyses showed that levels of stress response. protein HSP70 were significantly elevated in neurons exposed to low dose of curcumin, whereas levels of cleaved PARP were increased in neurons exposed to high dose of curcumin. These findings show that curcumin can modulate neuronal responses to glutamate, and suggest possible use of curcumin and related compounds in the prevention and/or treatment of neurodegenerative disorders.

우포늪, 순천만, 서해 갯벌에서부터 분리한 황산염/황-환원 세균의 특성 분석

김소정,민의기,홍희지,김종걸,정만영,차인태,이성근,Kim, So-Jeong,Min, Ui-Gi,Hong, Heeji,Kim, Jong-Geol,Jung, Man-Young,Cha, In-Tae,Rhee, Sung-Keun 한국미생물학회 2014 미생물학회지 Vol.50 No.3

Sulfur compound includes major electron acceptors for anaerobic respiration. In this study, cultivation-based study on sulfate- and sulfur-reducing bacteria of various wetlands of Korea was attempted. To isolate sulfate- and sulfur-reducing bacteria, anaerobic roll tube method was used to obtain typical black colonies of sulfate- and sulfur-reducing bacteria. Total 11 strains obtained were tentatively identified based on comparative 16S rDNA similarity and physiological property analysis. All sulfate-reducing bacteria (8 strains) belonged to genus Desulfovibrio with >99% 16S rDNA similarities. Three sulfur reducing bacteria were also isolated: two and one isolates were affiliated with Sulfurospirillum and Desulfitobacterium, respectively. These sulfate- and sulfur-reducing bacteria were able to utilize lactate and pyruvate and sulfite and thiosulfate as common electron donors and electron acceptors, respectively. This case study will provide fundamental information for obtaining useful indigenous sulfate- and sulfur-reducing bacteria from Korean wetlands employing various combinations of cultivation conditions. 황화합물은 혐기성환경에서 혐기성호흡을 위한 매우 중요한 전자수용체이다. 본 연구를 통하여 한국의 다양한 습지에서 배양을 통한 황산염/황-환원세균의 특성연구를 실시하였다. 이를 분리하기 위하여 혐기성 roll tube법을 통해 총 11개의 순수 배양체를 확보하였다. 16S rDNA를 이용한 계통분석 및 상동성 분석을 실시하여 Desulfovibrio 속의 세균 8종, Sulfurospirillum 속의 세균 2종, Desulfitobacterium 속의 세균 1종을 얻을 수 있었다. 이들 황산염/황-환원세균은 모두 lactate와 pyruvate를 전자공여체로 이용하였으며, sulfite and thiosulfate를 전자수용체로 이용할 수 있었다. 앞으로, 다양한 전자공여체와 배양조건을 통하여 유용한 절대혐기성 황산염/황-환원세균의 생물자원 확보에 기여할 것으로 기대된다.

In vitro 및 In vivo Assay를 통한 중금속의 에스트로겐성 평가

박철(Chul Park),김소정(So-Jung Kim),신완철(Wan-Chul Shin),김혜경(Hae-Gyoung Kim),최석영(Suck-Young Choe) 한국식품영양과학회 2004 한국식품영양과학회지 Vol.33 No.9

식품오염 관련 중금속들의 에스트로겐성을 in vitro 와 in vivo 분석방법을 병행하여 평가하였다. 분석방법은 1) estrogen receptor dependent transcriptional expression 분석법, 2) E-screen assay 그리고, 3) 마우스 자궁비대시험 (uterotropic assay)을 사용하였다. 시험에 사용한 물질로는 17β-estradiol, diethylstilbestrol(DES), arsenic oxide, bis (tri-n-butyltin), cadmium chloride, chromium chloride, lead acetate, mercuric chloride을 사용하였다. Estrogen receptor dependent transcriptional expression 분석 결과, bis(tri-nbutyltin) > cadmium chloride > chromium chloride 순으로 에스트로겐성이 크게 나타났으며, mercuric chloride, lead acetate, arsenic oxide는 거의 나타나지 않았다. E-screen test 결과, bis(tri-n-butyltin) > cadmium chloride > chromium chloride 순으로 에스트로겐성이 크게 나타났으며, mercuric chloride, lead acetate, arsenic oxide는 거의 나타나지 않았다. 자궁비대시험 결과도 마찬가지로 bis(tri-nbutyltin), cadmium chloride, chromium chloride은 자궁중량 비대를 크게 초래하였으며, 반면에 mercuric chloride, lead acetate, arsenic oxide는 그러한 효과가 미약하거나 없었다. 세 분석방법 결과 bis(tri-n-butyltin), cadmium chloride, chromium chloride 순으로 에스트로겐성이 크게 나타났다. 이러한 결과는 최근 bis(tri-n-butyltin)과 cadmium chloride이 에스트로겐성이 있다는 다른 연구결과들과 잘 일치하며, 또한 크롬화합물도 에스트로겐성이 있다는 것을 새롭게 제시하고 있다. 본 연구는 세 단계 수준(전사활성화단계, 세포증식작용, in vivo assay)의 분석을 병행함으로써 수많은 중금속의 에스트로겐성을 효과적으로 평가할 수 있다는 것을 제시해주고 있다. The estrogenicities of six heavy metal compounds, which contaminate frequently in foods, were assayed using a combination of in vitro and in vivo assays. The assays were 1) estrogen receptor dependent transcriptional expression assay, 2) E-screen assay and, 3) the uterotropic assay in mice. The chemicals studied were 17β-estradiol, diethylstilbestrol (DES), arsenic oxide, bis(tri-n-butyltin), cadmium chloride, chromium chloride, lead acetate, and mercuric chloride. Using the estrogen receptor dependent transcriptional expression assay, the following estrogenicity ranking was measured: bis(tri-n-butyltin) > cadmium chloride > chromium chloride >> mercuric chloride >lead acetate = arsenic oxide. Using E-screen test, the following estrogenicity ranking was measured: bis(tri-n-butyltin) > cadmium chloride > chromium chloride >> mercuric chloride > lead acetate = arsenic oxide. Results from the uterotropic assay showed that bis(tri-n-butyltin), cadmium chloride, chromium chloride caused an increase in uterine wet weight, while lead acetate, mercuric chloride, and arsenic oxide failed to do so. Bis(tri-n-butyltin), cadmium chloride and chromium chloride showed the highest estrogenicity in three assay systems. Recent studies suggesting that bis(tri-n-butyltin), cadmium chloride have estrogenicities are compatible with the present finding. Furthermore, our study is suggesting that chromium chloride may be estrogenic. The results demonstrate that this three level-assay combination (transcriptional activation, cell proliferation, and an in vivo effect in an estrogen-responsive tissue) could serve as a useful method to assess the estrogenicity of heavy metals.

신뢰도 예측 모델 개선방안에 대한 연구

김소정(So Jung Kim),서양우(Yang Woo Seo),이승상(Seung Sang Lee),김정태(Jung Tae Kim) 한국산학기술학회 2021 한국산학기술학회논문지 Vol.22 No.10

본 연구에서는 신뢰도 예측의 정확성을 향상시키기 위해 개선된 신뢰도 예측 모델을 제안한다. 예측의 정확성을 높이기 위해, 예측하고자 하는 대상의 BOM과 기술자료를 확보한 후, 첫째, 필드 데이터와 유사 장비 데이터를 사용하여 고장률 값을 예측한다. 필드 데이터가 가장 우선시 되어야 하며 없는 경우 유사 장비 데이터를 사용한다. 둘째, 앞선 데이터가 존재하지 않는 경우, 예측 규격을 활용한다. 전자 부품은 복합스트레스의 경우, 고장률 혼합방법 사용을 가장 우선시하며 단일스트레스인 경우, MIL-HDBK-217F를 우선시하여 사용한다. 기계 부품은 NSWC를 우선시하여 사용한다. 신뢰도 예측 후 commercial일 경우 ANSI/VITA를 적용해 팩터값을 보정해준다. 셋째, 고장의 특성을 고려해주기 위해 FMD, 환경조건보정(MIL-HDBK-338B), NOC(TO 00-20-2)를 이용하여 신뢰도 예측값을 보정하여 MTBF를 산출한다. 제시한 신뢰도 예측 모델과 A 시스템 분석보고서의 데이터를 활용하여 정확성을 검증하였다. A 시스템 분석보고서의 데이터에 대하여 검증한 결과, 기존 분석값보다 더 정확한 값을 확인하였다. This paper proposes an improved reliability prediction model to improve the accuracy of a reliability prediction. The BOM and technical data of the target to predict were obtained to improve the accuracy of the prediction. Field data and similar equipment data were used to predict the failure rate values. Field data should be a top priority, and if not, similar equipment data should be used. Second, the prediction specification was utilized if the preceding data did not exist. For electronic components, failure rate mixing models were prioritized in the presence of complex stress, and MIL-HDBK-217F was prioritized in the presence of single stress. Mechanical components used the NSWC. After performing a reliability prediction, ANSI/VITA was used to correct the factor value if the part was commercial. Third, to consider the failure properties, the reliability prediction value was corrected using the FMD, environment condition correction, and NOC. The proposed reliability prediction model and the data from the A-system analysis report were used to verify its accuracy. The data in the A-system analysis report confirmed a more accurate value than the current analysis value.

창의적 사고활동을 통한 영어 체험학습의 효과

김소정(So Jung Kim),김현주(Hyun-Ju Kim) 한국중원언어학회 2017 언어학연구 Vol.0 No.45

This study intended to investigate the effects of English experiential learning through creative thinking activities. The experiments were implemented in the 2<SUP>nd</SUP> grade class at a D elementary school. A total of 21 students participated in this study. The effects of English experiential learning through creative thinking activities were evaluated in three categories: English comprehension ability (listening and reading skills), linguistic creativity (fluency, originality, refinement, abstractness), and affection (interests, attitudes, confidence) before and after the English experiential learning. Based on the data analysis, it was found that English experiential learning promoted students’ English comprehension ability, linguistic creativity, and had a positive influence on students’ affective aspects. Students showed both verbal fluency using more words and expressions that they had already learned in class and verbal flexibility by explaining words or expressions that were not used before. Students also revealed their linguistic creativity by creating and explaining new expressions with their own unique ideas. This study suggests the possibility as well as the directions of the application of English experiential learning through creative thinking activities in an elementary class.

박물관 전시공간구조와 관람행태의 상관관계 재해석에 관한 연구

김소정(Kim, So-Joung),정성욱(Jung, Sung-Wook) 한국실내디자인학회 2011 한국실내디자인학회논문집 Vol.20 No.6

The purpose of this study is to analyze the correlation between spatial space structure and visitors` behavior and interpret visitors` behavior concretely from the aspect of exhibition environments. So, this study intends to qualify spatial space structure with integration, connectivity and control value by utilizing space syntax, limit to tracking score among the analysis index and reinterpret with exhibition density and extend of eyesight among the exhibition environments. The results of this study are as follows; First, in case of museums, tracking score shows plus corelation with connectivity and control value among the space syntax variables and very low correlation with integration. In case of art museums, tracking score shows plus correlation with integration and wide variable is judged to more useful to analyze visitor"s behavior than minor variable. Second, museums doesn"t make a great effect on visitors` behavior from the aspect of extent of eyesight, but from the aspect of exhibition density, visitors relatively watched evenly without short cut at the early stage of exhibition in spite of high exhibition density. And, they conducted short cut as they went to the middle stage of exhibition on the course of watching although the numerical value of exhibition density is low. Third, in case of art museums, visitors` behavior was relatively influenced by exhibition density, not extent of eyesight. But, as they went to the high level on the course of watching, watching speed became rapid and watching length became short in the place the value of extent of eyesight was high. Its reason is judged to be easy to grasp position or space structure of the next exhibition room visually. Therefore, when the concentration of watching is necessary from the aspect of exhibition, to control exhibition density properly before the space is useful to draw visiting to exhibition space afterward.

미국 개신교 선교사의 중국화 번역 전략: 『Education in Japan』에서 『문학흥국책(文學興國策)』으로의 전변

김소정 ( So Jung Kim ) 한국외국어대학교 국제지역연구센터 중국연구소 2010 中國硏究 Vol.49 No.-

Education in Japan: A Series of Letters is the collection of the thirteen letters introducing modern American education system and ideology. The letters were written by the renowned American people in educational and political arena, and sent to Mori Arinori, who was groping for the concrete methods for the propelling of the modernization of Japanese education system, and were published as the book in New York in 1873. Young John Allen, Chinese name 林樂知) translated this book under the title Wen Xue Xing Guo Ce,(文學興國策), State Development Strategy through Education, and Ren Tingyu(任廷旭) polished before it was published by Society for the Diffusion of Christian and General Knowledge among the Chinese in Shanghai, in 1896. The publication of this book brought huge impact on the reforming of the Chinese education system for modernization. 1896, the year this book was published, was just after when China was defeated by Japan in the China Japan war, and realized the necessity of fundamental reforming of the state. Allen believed that reforming of education system is the most wanted in order to educate the ignorant Chinese people and thoroughly change the traditional Chinese Confucian ideology. He published Wen Xue Xing Guo Ce in order to show the concrete model for education reform. He adopted domestication translation strategy in translating the American education system and ideology. He believed that domestication translation will defuse Chinese intellectual`s resistance against the unfamiliar culture and is efficient to find more number of readers. Propagation of Christianity in China, his ultimate goal as a missionary, was also concealed in this translation. The book obtained a new significance due to Allen`s domestication strategy, and the American writers` original intention, that is the modernization of Japanese education, was refracted. The domestication translation strategy of this book is confirmed in the change of the contents, addition of new meanings, adaption to Chinese language customs, reflection of Chinese world view, utilizing of various Confucian terminologies.