선천 수정체이탈 소아에서 수정체적출술의 장기 결과

김소영,김성준,유영석,So Young Kim,Seong Jun Kim,Young Suk Yu 대한안과학회 2005 대한안과학회지 Vol.46 No.2

Purpose: To analyze the clinical features and the long term visual results of children with ectopia lentis after lensectomy. Methods: Enrolled in this study were 79 eyes of 43 patients who were operated on and followed up for at least 3 years. We performed a retrospective analysis of the patient records. Results: The mean age at diagnosis was 4.6 years, mean age at surgery was 5.7 years and average follow-up was 7.1 years. Of the 43 patients with bilateral ectopia lentis, 7 underwent monocular surgery. The mean age at diagnosis was higher and mean postoperative BCVA was significantly lower in the monocular surgery group than in the binocular surgery group. All eyes showed reduced hyperopia for 5 years postoperatively, but the reduction rate of the monocular operated eyes was significantly lower than that of the binocular operated eyes (P<0.05). No complication occurred during surgery and 1 eye (1.3%) with Marfan syndrome showed retinal detachment 9 years after surgery. Conclusions: Surgical treatment of ectopia lentis was safe and showed good visual outcomes after 7.1 years of follow-up. Nevertheless, consideration must be given to the possibility of amblyopia due to the difference of the degree of dislocation between the two eyes.

고려 태조대 대거란 정책의 전개와 그 성격

김소영(Kim. So-young) 백산학회 2001 白山學報 Vol.- No.58

This thesis is to investigate how Koryŏ dynasty’s policy toward Kitan(契丹) changed before and after its unification of the late Three Kingdom(後三國) and the historical significances of it. At first, the first King Strived for domestic stability and outside duty within the Korean Peninsula and formed a friendly relation-ships with the late Tang(唐) and Owŏl(吳越) of China and Parhae(渤海). Since there hadn’t been any direct threat of Kitan yet, he made no response to its approach in 922. However, as Kitan destroyed Parhae in 926, Koryo felt the threat of Kitan;s expansion policy and began to send envoys to Kitan and as rivalry between Koryŏ and the late late Paekche(後百濟) had become severe since 927. Koyrŏ actively tied itself with the late Tang while loosening its tie with Kitan. Because Kitan concentrated its efforts to advance into the central temtory of China, its power over Parhae weakened, so was its threat to Koyro. In 938, throught a Chinese momk(胡僧), Mala(襪囉), the King proposed China to attack Kitan on both sides, and on 942 as the relationship between the late Chin(後晋) and Kitan become worse he severed diplomatic relations with Kitan by making the so-called “Manpu bridge scandal(萬夫橋事件)”. The hard- line policy in the latter period aimed at weakening Kitan’s pressure through a close relationship with the late Chin. Also to justify itself abroad and stabilize northern regions by winning the residual forces of Parhae such as Yŏjin(女眞) and the late Parhae(後渤海) over to its side. Koryŏ Dynasty’s policy toward Kitan during the reign of the first king has historical significances as follows: first, policy toward Kitan was established according to the political changes of the surrounding countries and Koryŏ’s practical interests related to them; second, the hard-line policy after the unification was to stabilize northern frontiers by gaining the residual forces of Parhae over to Koryŏ’s side rather than to actively advance northward; third, policy toward Kitan at this time was closely connected with the movements of Parhae people after its downfall; fourth, the significance of the first kings policy toward Kitan and diplomacy oriented to China is great Since they become the groundwork of early foreign policies of Koryŏ dynasty.

다가불포화지방산의 공역이중결합 유도체가 흰쥐의 혈청 지질 성분에 미치는 영향

김소영,김성희,김경업,Kim, So-Young,Kim, Sung-Hee,Kim, Gyeong-Eup 한국식품영양과학회 2007 한국식품영양과학회지 Vol.36 No.9

n-6계 linoleic acid의 함량이 높은 옥수수유 및 n-3계 linolenic acid의 함량이 높은 들깨유와 함유된 다가불포화지방산을 공역이중결합 유도체화 처리한 옥수수유 및 들깨유가 흰쥐의 혈청 지질개선에 미치는 영향을 비교 검토하기 위하여 S.D.계 숫 흰쥐에게 돈지 식이를 대조군으로 하고 옥수수유 10%, 들깨유 10%, 유도체화 처리한 옥수수유 10% 및 유도체화 처리한 들깨유 10%을 급여하여 4주간 실험 사육한 후 혈청 지질성분을 분석하였다. 유도체화 처리한 옥수수유(TCO)는 가스 크로마토그래피에 의해 3개의 linoleic acid의 유도체가 확인되었고 유도체화 처리한 들깨유(TPO)에서는 5개의 linolenic acid의 유도체가 확인되었다. 체중증가량 및 식이섭취량은 유도체화 처리한 옥수수유 및 들깨유 급여군에서 유의성 있게 낮았다. 혈청 총콜레스테롤 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며, 특히 유도체화 처리한 옥수수유 및 들깨유 급여군에서 더욱 낮았다. HDL-콜레스테롤 농도는 대조군에 비해 전실험군에서 유의적으로 높았다. 혈청 LDL 및 LDL-콜레스테롤 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며 유도체화 처리한 옥수수유 및 들깨유 급여군에서 더욱 낮은 경향을 보였고, 특히 유도체화 처리한 들깨유 급여군에서 가장 낮았다. VLDL 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며, chylomicron 농도는 유도체화 처리한 유지 급여군에서 유의성 있게 낮았고 특히 유도체화 처리한 들깨유 급여군에서 가장 낮았다. 혈청 유리콜레스테롤 농도는 대조군에 비해 전 실험군간에 유의적인 차이는 없는 반면 유도체화 처리한 옥수수유 및 들깨유 급여군에서 약간 낮았다. 혈청 중성지질 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며, 특히 유도체화 처리한 들깨유 급여군에서 가장 낮았다. 인지질 농도는 옥수수유 급여군이 대조군에 비해 약간 높게 나타난 반면 유도체화 처리한 유지 급여군은 약간 낮은 수준이었다. 이상의 결과 n-6계 linoleic acid의 함량이 높은 옥수수유 및 n-3계 linolenic acid 함량이 높은 들깨유의 공역이중결합유도체의 섭취는 혈중 총콜레스테롤, LDL-콜레스테롤, chylomicron 및 중성지질 농도를 감소시킴으로써 혈청 지질 개선효과가 있는 것으로 나타났으며, 특히 n-3계 들깨유의 공역이중결합 유도체 급여군이 혈청 지질 개선효과가 가장 큰 것으로 나타났다. This study was designed to examine the effects of n-6 PUFA rich corn oil, n-3 PUFA rich perilla oil and their conjugated double bond derivatives on serum lipids status in rats. Experimental diets containing lard (control), corn oil (CO), perilla oil (PO), conjugated double bond derivatives of n-6 PUFA rich corn oil (TCO) and n-3 PUFA rich perilla oil (TPO) at the level of 10% (w/w) were fed to male Sprague Dawley rats for 4 weeks. TCO was found to have three derivatives of linoleic acid and TPO had five derivatives of linolenic acid by GC. Serum total cholesterol levels were significantly lower in the all experimental groups than in the control group, and particularly, the lowest in TCO and TPO groups. HDL-cholesterol concentrations were a little higher in the all experimental groups than in the control group, and TCO and TPO groups were not significantly different from CO and PO groups. Serum LDL, LDL-cholesterol, chylomicron and triglyceride concentrations were significantly lower in the all experimental groups than in the control group, remarkably lower in TCO group and particularly, the lowest in the TPO group. Serum free cholesterol and cholesteryl ester concentrations were lower in TCO and TPO groups than in CO and PO groups. From the above research, TCO and TPO groups were effective on the improvement of the lipid compositions in serum and particularly, TPO group was the most effective on the improvement of serum lipids.

중국 당대 문학출판 제도의 성립과 변화 ― ‘17년 시기’(1949-1966)를 중심으로

金昭英(Kim, So-young) 중국어문학연구회 2020 중국어문학논집 Vol.0 No.120

As part of research to identify the mechanism of China"s contemporary literary production, the study organized the country"s literature publication system. In this study, the period was limited to the so-called "17-year period," or the period from 1949 when New China was founded to 1966, just before the Cultural Revolution broke out. The literature publication system of the time, which had been prepared even before the founding of the country and changed little by little, differs greatly from that of Korea under the market economy and from that of China since the reform and opening of the socialist market economy. As a starting point for figuring out what the system is, I have dealt with management organizations and institutional policies that have largely influenced it in terms of publication and literature, respectively.

갈색거저리(Tenebrio molitor) 유충의 냉장 저장 중 산화 안정성에 관한 연구

김소영,손양주,김수희,김안나,이금양,황인경,Kim, So-Young,Son, Yang-Ju,Kim, Soo-Hee,Kim, An-Na,Lee, Geum-Yang,Hwang, In-Kyeong 한국식품조리과학회 2015 한국식품조리과학회지 Vol.31 No.1

The purpose of this study was to evaluate the changes on the characteristics of the oxidative stability of Tenebrio molitor larvae during cold storage at $4^{\circ}C$. Pretreatment for T. molitor larvae was designed into three methods: raw (R), freeze-dried (F.D.), and pan-fried (P.F.). The water content of the raw sample (61.46%) was higher than those of other samples (F.D.: 5.02%, P.F.: 3.67%) and its high water content was expected to facilitate the oxidation of the raw sample. In our results, the peroxide value and the carbonyl value of all of the samples increased and the raw sample, after storage for 18 day, showed the highest value. The pan-fried sample had no significant increase in its lactic acid content, acid value, and thiobarbituric acid value; whereas those values were increased in the raw sample and the freeze-dried sample (p<0.05). The browning reaction was more progressed in the pan-fried sample than other samples at 0 day, but there was no significant change during the storage. The raw sample and the freeze-dried sample had their browning indexes increase with the increasing storage period (p<0.05). The pan-fried sample produced less oxidation products than the freeze-dried sample, indicating that the unheated sample was more susceptible to oxidation than the heated samples. In conclusion, heating treatment and low water content would be effective for improving the safety and stability of T. molitor larvae during cold storage.

‘주체-타자’의 해체로부터 다시 타자를 사유하기: 다르덴 형제의 <약속>, <로나의 침묵>, <언노운 걸>을 중심으로

김소영 ( Kim So Young ) 한양대학교 현대영화연구소 2021 현대영화연구 Vol.17 No.3

작금의 시대는 여러 형상의 타자들을 매체를 통해 적극적으로 소환해내는, 이른바 타자의 시대이다. 벨기에 출신의 형제 감독인 장 피에르 다르덴(Jean-Pierre Dardenne)과 뤽 다르덴(Luc Dardenne)도 그들의 필모그래피를 통해 소외된 타자들에 주목하며 형식미학의 변화를 보여주고 있다. 본 연구는 작가론의 측면에서 최근 작품을 포함한 다르덴 형제의 영화 연구가 미비한 점을 감안하여, 1990년대부터 2010년대를 관통하는 < 약속(La promesse) >(1996), < 로나의 침묵(Le silence de Lorna) >(2008), < 언노운 걸(La Fille inconnue) >(2016)에 나타난 타자(성)의 재현 방식 및 그것과 연동되는 사유의 장으로 나아가고자 한다. 양자의 내용을 다루기 위하여 본론에서는 다음과 같은 세 층위의 분석을 수행한다. 첫째는 소외된 타자의 상황에 개입하면서 경험하는 ‘주체의 타자화’에 의한 윤리적 죄의식, 둘째는 일(一) 대 일의 관계에서 일 대 다(多)로 확장되는 ‘타자 대 타자(들)’의 관계적 얽힘, 셋째는 공통적 모티브인 ‘타자의 죽음’을 통해 ‘타자들과의 공생’으로 해체되어 가는 타자성에 관한 내용이다. 다르덴 형제의 영화 속 인물들은 이처럼 타자(성)라는 담론으로 수렴되지만, 우리와 그들 모두 세계라는 무대에서 상호작용 하며 ‘지금-여기’에 존재하는 주체이자 타자이다. 따라서 이분법적으로 경계 지어진 주체와 타자의 해체로부터 나아가 모든 존재를 개체적 타자들로 바라볼 때, 다르덴 형제와 관객이 지향하는 공존과 공생을 논할 수 있을 것이다. Current society is the so-called era of others, actively bringing up others in various forms. The Belgian film directors, Jean-Pierre Dardenne and Luc Dardenne, are also showing changes in formal aesthetics by constantly paying attention to alienated others through their filmography. Considering that prior research on the Dardenne brothers’ films was not included recent works, this study selected La promesse(1996) and Le silence de Lorna(2008) and La Fille inconnue(2016), the method of representation of the other and the field of thought interlocked with it. In order to deal with the contents of both, the following three layers of analysis are performed. The first is the ethical guilt caused by the ‘otherization of the subject’ that the character set as the subject experiences while intervening in the situation of the alienated other, and the second is the relational entanglement from ‘other-to-other’ to ‘other-to-others’. And the third is otherness that is being deconstructed into ‘coexistence with others’ through the common motif ‘death of others’. Although the characters in the Dardenne brothers’ films converge to the discourse of the other, we and them both interact on the stage of the world and are the subject and other in the here and now. Therefore, when we go beyond the dichotomous deconstruction of the subject and the other, and look at all beings as individual others, we can discuss the coexistence that the Dardenne brothers and the audience are aiming for.

진료를 받는 고혈압 환자의 혈압 조절과 관련된 의사 요인

김소영,조인숙,이재호,김지현,이은정,박종혁,이진석,김윤,Kim, So-Young,Cho, In-Sook,Lee, Jae-Ho,Kim, Ji-Hyun,Lee, Eun-Jung,Park, Jong-Hyock,Lee, Jin-Seok,Kim, Yoon 대한예방의학회 2007 예방의학회지 Vol.40 No.6

Objectives : Little is known about the physician-related factors that are associated with the management of Hypertension. The purpose of this study was to determine the physician-related factors associated with blood pressure control in hypertensive patients. Methods : We surveyed 154 physicians at 117 public health (subhealth) centers in Gyeonggi-do, Forty-one physicians completed the survey (response rates : 26.6%) and 31 physicians were finally included as the study subjects. Using the information obtained from the self-reported survey, we measured the physician-related factors associated with hypertension control, including their perception of hypertension, prescription patterns (combination prescription rates, specific antihypertensives prescription rates among patients with diabetes mellitus), and sociodemographic factors. We then collected data on blood pressure and medication use in patients seen by these physicians from the health center#s information system. We compared the physicians# perceived hypertension control rates with the actual rates, and then evaluated the rate of high overestimation (overestimation by more than 25% of the median degree of hypertension control rate overestimation) among the physicians. The physicians# antihypertensive prescription patterns were also evaluated. Multiple logistic regression analysis was used to evaluate the independent association between hypertension control and physician-related factors. Results : The physicians tended to overestimate the proportion of their patients with controlled blood pressure (79.5% perceived vs. 57.8% actual). The percentage of physicians with high overestimation was 35.5% (11 physicians). The physicians with lower control rates were more likely to highly overestimate their patients# control rates. Physicians with below-median actual control rates tended to prescribe fewer combination treatments for patients with uncontrolled blood pressure and angiotensin-converting enzyme inhibitors or fewer angiotensin receptor blockers for patients with diabetes mellitus. The rate of high overestimation by physicians was 1.31 times higher in patients with uncontrolled blood pressure than in patients with other conditions (OR=1.31, 95% CI : 1.17-1.48). Conclusions : Physicians have a tendency to overestimate the rates of hypertension control in their patients. Because physicians have a direct role in treatment outcomes, physicians# overestimation about hypertension management contributes to inadequate blood pressure control. Thus, interventions for improving physician# awareness regarding the management of patients with hypertension are needed.

SOD2와 NDPK2 유전자 집적에 의한 페튜니아의 아황산가스 저항성 증진

이수영(Su Young Lee),천경성(Kyeong-Seong Cheon),김소영(So Young Kim),권오현(O Hyeon Kwon),이혜진(Hye Jin Lee),김원희(Won Hee Kim),유봉식(Bong Sik Yoo) 한국원예학회 2016 원예과학기술지 Vol.34 No.1

유전자 집적에 의해 아황산가스 저항성 증진 페튜니아를 개발하고자 비생물적스트레스 저항성 유전자로 널리 알려진 SOD2 와 NDPK2유전자가 각각 도입된 SOD2 형질전환 계통 SOD2-2-1-1-35(T₄)[S(T₄)]와 NDPK2 형질전환 계통 NDPK2-7-1(T₂)[N7-1(T₂)]간 상호교잡을 실시하여 교잡 제1세대를 획득하였다. 교잡 제1세대 중 SOD2와 NDPK2유전자가 모두 집적된 개체 획득율은 32.1-73.0%이었고, SOD2와 NDPK2유전자가 모두 집적된 개체는 SOD2 또는 NDPK2유전자가 단독 도입된 개체에 비해 아황산가스 30ppm처리 피해율이 2.6-5.1배 낮아 아황산가스 저항성이 증진되었음을 확인하였다. 또한 아황산가스 저항성이 증진된 교잡 제1세대를 자가수분에 의해 세대진전 시켜 획득한 교잡 제2세대의 아황산가스 저항성 검정을 통하여 교잡 제1세대에서의 아황산가스 저항성이 후대에서도 안정적으로 발현함을 확인하였다. 또한, 광합성 효율 증진 조사를 통해 아황산가스 저항성이 증진된 SOD2와 NDPK2유전자 집적 후대가 아황산 가스에 대한 스트레스를 덜 받고 있음을 확인하였고, RT-qPCR분석을 통해 SOD2와 NDPK2유전자 집적 후대의 아황산가스 저항성 증진이 SOD2와 NDPK2 유전자 집적에 의한 효과임을 확인하였다. The aim of this study was to develop a transgenic petunia with enhanced resistance to sulfur dioxide (SO₂) gas by stacking two genes, SOD2 and NDPK2, which are both known to confer resistance to abiotic stresses. The first-generation hybrids (TF1) were obtained through reciprocal crosses between an SOD2-transgenic line SOD2-2-1-1-35(T₄)[S(T₄)] and an NDPK2- transgenic line NDPK2-7-1(T₂)[N7-1(T₂)]. Approximately 32.1-73.0% of the first-generation hybrids (TF₁) carried both SOD2 and NDPK2 genes. These hybrids showed 2.6 and 5.1 times less damage than hybrids carrying only SOD2 or NDPK2 genes, respectively, when they were treated with SO₂ gas at 30 ppm. This confirmed that the heterozygous hybrids were more resistant to SO₂ than the hybrids carrying either one of the resistance genes. Second-generation hybrids (TF₂) were obtained by selfing the TF₁ individuals. We confirmed the expression of the stacked genes in the TF₂ hybrids by phenotypic observation of their response to SO₂ gas at 30 ppm as well as using RT-qPCR and photosynthetic efficiency.

하안검의 가피와 안질환을 동반한 쯔쯔가무시병 2예

김소영,노규화,정문선,So Young Kim,Kyu Hwa Roh,Moon Sun Jung 대한안과학회 2006 대한안과학회지 Vol.47 No.11

Purpose: To report two cases of tsutsugamushi disease, showing ocular manifestations with eschars on the lower eyelids. Methods: Two patients who have tsutsugamushi disease with ocular manifestations were examined by standard ophthalmic procedures. Eschars were observed in both patients on the medial canthal lower lid. Conjunctival injection and episcleral vessel dilations were also observed in both patients. One patient had limbal vasculitis with pannus. Results: It is possible that eschars, which are the pathognomonic sign in tsutsugamushi disease, can occur on the eyelid, as well as on the axilla, perineum, abdomen, and extremities, which have been commonly observed sites. Ocular manifestations, including conjunctival injection, episcleral vessel dilation, or limbitis may be observed. These conditions may respond well to treatment with 0.1% Fluorometholone.

남매에서 비슷한 시기에 발생한 Henoch-$Sch{\ddot{o}}nlein$ 자반증 2례

김소영,임인석,유병훈,Kim, So-Young,Lim, In-Seok,Yoo, Byoung-Hoon 대한소아신장학회 2000 Childhood kidney diseases Vol.4 No.2

저자들은 남매에서 3주 정도의 차이를 둔 비슷한 시기에 피부의 자반성 구진, 관절의 부종 및 관절통을 주소로 내원하여 HS 자반증으로 진단받은 두명의 환아를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Henoch-$Sch{\ddot{o}}nlein$ purpura(HSP) frequently follows upper respiratory infection, and one of the causes of this discase is inferred to $\beta$-hemolytic streptococcal infection, but the relationship is still unclear. familial tendency of this disease is unclear, too. Also genetic relationship of this disease has been in a controversy yet. We experienced two cases of HSP in brother and sister at similar period, and report this case with review of related literatures.