다가불포화지방산의 공역이중결합 유도체가 흰쥐의 혈청 지질 성분에 미치는 영향

김소영,김성희,김경업,Kim, So-Young,Kim, Sung-Hee,Kim, Gyeong-Eup 한국식품영양과학회 2007 한국식품영양과학회지 Vol.36 No.9

n-6계 linoleic acid의 함량이 높은 옥수수유 및 n-3계 linolenic acid의 함량이 높은 들깨유와 함유된 다가불포화지방산을 공역이중결합 유도체화 처리한 옥수수유 및 들깨유가 흰쥐의 혈청 지질개선에 미치는 영향을 비교 검토하기 위하여 S.D.계 숫 흰쥐에게 돈지 식이를 대조군으로 하고 옥수수유 10%, 들깨유 10%, 유도체화 처리한 옥수수유 10% 및 유도체화 처리한 들깨유 10%을 급여하여 4주간 실험 사육한 후 혈청 지질성분을 분석하였다. 유도체화 처리한 옥수수유(TCO)는 가스 크로마토그래피에 의해 3개의 linoleic acid의 유도체가 확인되었고 유도체화 처리한 들깨유(TPO)에서는 5개의 linolenic acid의 유도체가 확인되었다. 체중증가량 및 식이섭취량은 유도체화 처리한 옥수수유 및 들깨유 급여군에서 유의성 있게 낮았다. 혈청 총콜레스테롤 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며, 특히 유도체화 처리한 옥수수유 및 들깨유 급여군에서 더욱 낮았다. HDL-콜레스테롤 농도는 대조군에 비해 전실험군에서 유의적으로 높았다. 혈청 LDL 및 LDL-콜레스테롤 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며 유도체화 처리한 옥수수유 및 들깨유 급여군에서 더욱 낮은 경향을 보였고, 특히 유도체화 처리한 들깨유 급여군에서 가장 낮았다. VLDL 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며, chylomicron 농도는 유도체화 처리한 유지 급여군에서 유의성 있게 낮았고 특히 유도체화 처리한 들깨유 급여군에서 가장 낮았다. 혈청 유리콜레스테롤 농도는 대조군에 비해 전 실험군간에 유의적인 차이는 없는 반면 유도체화 처리한 옥수수유 및 들깨유 급여군에서 약간 낮았다. 혈청 중성지질 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며, 특히 유도체화 처리한 들깨유 급여군에서 가장 낮았다. 인지질 농도는 옥수수유 급여군이 대조군에 비해 약간 높게 나타난 반면 유도체화 처리한 유지 급여군은 약간 낮은 수준이었다. 이상의 결과 n-6계 linoleic acid의 함량이 높은 옥수수유 및 n-3계 linolenic acid 함량이 높은 들깨유의 공역이중결합유도체의 섭취는 혈중 총콜레스테롤, LDL-콜레스테롤, chylomicron 및 중성지질 농도를 감소시킴으로써 혈청 지질 개선효과가 있는 것으로 나타났으며, 특히 n-3계 들깨유의 공역이중결합 유도체 급여군이 혈청 지질 개선효과가 가장 큰 것으로 나타났다. This study was designed to examine the effects of n-6 PUFA rich corn oil, n-3 PUFA rich perilla oil and their conjugated double bond derivatives on serum lipids status in rats. Experimental diets containing lard (control), corn oil (CO), perilla oil (PO), conjugated double bond derivatives of n-6 PUFA rich corn oil (TCO) and n-3 PUFA rich perilla oil (TPO) at the level of 10% (w/w) were fed to male Sprague Dawley rats for 4 weeks. TCO was found to have three derivatives of linoleic acid and TPO had five derivatives of linolenic acid by GC. Serum total cholesterol levels were significantly lower in the all experimental groups than in the control group, and particularly, the lowest in TCO and TPO groups. HDL-cholesterol concentrations were a little higher in the all experimental groups than in the control group, and TCO and TPO groups were not significantly different from CO and PO groups. Serum LDL, LDL-cholesterol, chylomicron and triglyceride concentrations were significantly lower in the all experimental groups than in the control group, remarkably lower in TCO group and particularly, the lowest in the TPO group. Serum free cholesterol and cholesteryl ester concentrations were lower in TCO and TPO groups than in CO and PO groups. From the above research, TCO and TPO groups were effective on the improvement of the lipid compositions in serum and particularly, TPO group was the most effective on the improvement of serum lipids.

태양광 물 분해를 통한 수소 생산용 Cu₂O/CuO 이종접합 광전극의 제작 및 광전기화학적 특성

김소영,김효진,홍순구,김도진,Kim, Soyoung,Kim, Hyojin,Hong, Soon-Ku,Kim, Dojin 한국재료학회 2016 한국재료학회지 Vol.26 No.11

We report on the fabrication and characterization of a novel $Cu_2O/CuO$ heterojunction structure with CuO nanorods embedded in $Cu_2O$ thin film as an efficient photocathode for photoelectrochemical (PEC) solar water splitting. A CuO nanorod array was first prepared on an indium-tin-oxide-coated glass substrate via a seed-mediated hydrothermal synthesis method; then, a $Cu_2O$ thin film was electrodeposited onto the CuO nanorod array to form an oxide semiconductor heterostructure. The crystalline phases and morphologies of the heterojunction materials were examined using X-ray diffraction and scanning electron microscopy, as well as Raman scattering. The PEC properties of the fabricated $Cu_2O/CuO$ heterojunction photocathode were evaluated by photocurrent conversion efficiency measurements under white light illumination. From the observed PEC current density versus voltage (J-V) behavior, the $Cu_2O/CuO$ photocathode was found to exhibit negligible dark current and high photocurrent density, e.g. $-1.05mA/cm^2$ at -0.6 V vs. $Hg/HgCl_2$ in $1mM\;Na_2SO_4$ electrolyte, revealing the effective operation of the oxide heterostructure. The photocurrent conversion efficiency of the $Cu_2O/CuO$ photocathode was estimated to be 1.27% at -0.6 V vs. $Hg/HgCl_2$. Moreover, the PEC current density versus time (J-T) profile measured at -0.5 V vs. $Hg/HgCl_2$ on the $Cu_2O/CuO$ photocathode indicated a 3-fold increase in the photocurrent density compared to that of a simple $Cu_2O$ thin film photocathode. The improved PEC performance was attributed to a certain synergistic effect of the bilayer heterostructure on the light absorption and electron-hole recombination processes.

진료를 받는 고혈압 환자의 혈압 조절과 관련된 의사 요인

김소영,조인숙,이재호,김지현,이은정,박종혁,이진석,김윤,Kim, So-Young,Cho, In-Sook,Lee, Jae-Ho,Kim, Ji-Hyun,Lee, Eun-Jung,Park, Jong-Hyock,Lee, Jin-Seok,Kim, Yoon 대한예방의학회 2007 예방의학회지 Vol.40 No.6

Objectives : Little is known about the physician-related factors that are associated with the management of Hypertension. The purpose of this study was to determine the physician-related factors associated with blood pressure control in hypertensive patients. Methods : We surveyed 154 physicians at 117 public health (subhealth) centers in Gyeonggi-do, Forty-one physicians completed the survey (response rates : 26.6%) and 31 physicians were finally included as the study subjects. Using the information obtained from the self-reported survey, we measured the physician-related factors associated with hypertension control, including their perception of hypertension, prescription patterns (combination prescription rates, specific antihypertensives prescription rates among patients with diabetes mellitus), and sociodemographic factors. We then collected data on blood pressure and medication use in patients seen by these physicians from the health center#s information system. We compared the physicians# perceived hypertension control rates with the actual rates, and then evaluated the rate of high overestimation (overestimation by more than 25% of the median degree of hypertension control rate overestimation) among the physicians. The physicians# antihypertensive prescription patterns were also evaluated. Multiple logistic regression analysis was used to evaluate the independent association between hypertension control and physician-related factors. Results : The physicians tended to overestimate the proportion of their patients with controlled blood pressure (79.5% perceived vs. 57.8% actual). The percentage of physicians with high overestimation was 35.5% (11 physicians). The physicians with lower control rates were more likely to highly overestimate their patients# control rates. Physicians with below-median actual control rates tended to prescribe fewer combination treatments for patients with uncontrolled blood pressure and angiotensin-converting enzyme inhibitors or fewer angiotensin receptor blockers for patients with diabetes mellitus. The rate of high overestimation by physicians was 1.31 times higher in patients with uncontrolled blood pressure than in patients with other conditions (OR=1.31, 95% CI : 1.17-1.48). Conclusions : Physicians have a tendency to overestimate the rates of hypertension control in their patients. Because physicians have a direct role in treatment outcomes, physicians# overestimation about hypertension management contributes to inadequate blood pressure control. Thus, interventions for improving physician# awareness regarding the management of patients with hypertension are needed.

갈색거저리(Tenebrio molitor) 유충의 냉장 저장 중 산화 안정성에 관한 연구

김소영,손양주,김수희,김안나,이금양,황인경,Kim, So-Young,Son, Yang-Ju,Kim, Soo-Hee,Kim, An-Na,Lee, Geum-Yang,Hwang, In-Kyeong 한국식품조리과학회 2015 한국식품조리과학회지 Vol.31 No.1

The purpose of this study was to evaluate the changes on the characteristics of the oxidative stability of Tenebrio molitor larvae during cold storage at $4^{\circ}C$. Pretreatment for T. molitor larvae was designed into three methods: raw (R), freeze-dried (F.D.), and pan-fried (P.F.). The water content of the raw sample (61.46%) was higher than those of other samples (F.D.: 5.02%, P.F.: 3.67%) and its high water content was expected to facilitate the oxidation of the raw sample. In our results, the peroxide value and the carbonyl value of all of the samples increased and the raw sample, after storage for 18 day, showed the highest value. The pan-fried sample had no significant increase in its lactic acid content, acid value, and thiobarbituric acid value; whereas those values were increased in the raw sample and the freeze-dried sample (p<0.05). The browning reaction was more progressed in the pan-fried sample than other samples at 0 day, but there was no significant change during the storage. The raw sample and the freeze-dried sample had their browning indexes increase with the increasing storage period (p<0.05). The pan-fried sample produced less oxidation products than the freeze-dried sample, indicating that the unheated sample was more susceptible to oxidation than the heated samples. In conclusion, heating treatment and low water content would be effective for improving the safety and stability of T. molitor larvae during cold storage.

Vitamin C가 방사선과 Aflatoxin B₁을 처리한 흰쥐의 간세포에서 Aflatoxin B₁-DNA Adduct 형성에 미치는 영향

김소영,김한수,강진순,Kim, Soyoung,Kim, Hansoo,Kang, Jin-Soon 한국식품저장유통학회 2014 Food Science and Preservation Vol.21 No.5

The objective of this study was to examine the effects of vitamin C on the formation of aflatoxin $B_1$ ($AFB_1$)-DNA adduct and $AFB_1$-induing cellular oxidative damage in rat livers treated with radiation and $AFB_1$. Six-week-old male Sprague-Dawley rats were randomly divided into five groups: the control group, the $AFB_1$-treated group, the group treated with $AFB_1$ and vitamin C, the group treated with X-ray and $AFB_1$, and the group treated with X-ray and $AFB_1$ with vitamin C. On the first day of the experiment, only one dose of X-rays was exposed to the entire liver at 1,500 cGy. Next, vitamin C was injected at 10 mg/kg body weight via intraperitoneal injection, followed an hour later by the administration of 0.4 mg/kg of $AFB_1$ via intraperitoneal injection. These treatments were administered every three days for 15 days. On the 16th day, the animals were sacrificed. The $AFB_1$ contents of the rat sera were determined via indirect competitive ELISA. In the quantitative analysis of $AFB_1$ in the rat sera via ELISA, $5.17{\pm}0.34ng/mL$ of $AFB_1$ was detected in the $AFB_1$-treated groups, but the amount decreased more significantly to $3.23{\pm}0.76ng/mL$ in the groups treated with $AFB_1$ and vitamin C (p<0.01) than in the $AFB_1$-treated groups. The effect of vitamin C on $AFB_1$-DNA adduct formation was determined via ELISA. The values of $AFB_1$-DNA adduct formation were $9.38{\pm}0.41ng/mL$ in the $AFB_1$-treated groups, but the amount decreased more significantly to $5.28{\pm}0.32ng/mL$ in the groups treated with $AFB_1$ and vitamin C (p<0.01) than in the $AFB_1$-treated groups. Immunohistochemistry revealed that the accumulation of the $AFB_1$ was not observed in the normal liver tissue (G1). The $AFB_1$-positive materials were observed in the central vein and the portal vein of the liver tissue from the $AFB_1$(G2) treatment or the X-ray and $AFB_1$(G4) co-treatment, but the $AFB_1$-positive materials were observed weakly in the group treated with vitamin C (G3 and G5). These results indicate that vitamin C had ameliorating effects on the $AFB_1$ accumulation of liver tissue.

In Vitro Study on the Bond Strength Between 3D-Printed Resin and Resin Cement for Pediatric Crown Restoration

김소영,신유석,김익환,송제선,So Yung Kim,Yoosoek Shin,Ik-Hwan Kim,Je Seon Song Korean Academy of Pediatric Dentistry 2023 대한소아치과학회지 Vol.50 No.1

A 3D-printed resin crown is a novel option for esthetic crown restoration for primary teeth, which are typically bonded with resin cement. The purpose of this study was to evaluate the bonding ability of a 3D printing resin and compare it with other indirect resin materials for crown fabrication. The shear bond strengths of two 3D printing resin materials, Graphy (GP) and NextDent (NXT), and two indirect resin materials, VIPI Block (VIPI) and MAZIC Duro (MZ), were compared in the study. For all materials, the shear bond strength at the interface between the surface of the resin material and resin cement was measured. The mean shear bond strength values of GP, NXT, MZ, and VIPI were 23.29 ± 3.88, 26.14 ± 4.67, 25.41 ± 4.03, and 18.79 ± 4.26 MPa, respectively. There was no significant difference among the SBSs of GP, NXT and MZ except for VIPI. The result of this study indicates that the 3D printing resin meets the essential requirement for clinical use by showing clinically adequate bond strength.

Au 플라워가 성장된 하이브리드형 탄소 나노튜브 마이크로 섬유 기반 유연한 고민감성 압력 센서 연구

김소영,김도환,Kim, So Young,Kim, Do Hwan 한국섬유공학회 2016 한국섬유공학회지 Vol.53 No.1

Pressure-sensitive electronic skin (e-skin) has gained importance in the fields of prosthetics, health monitoring, sensitive tactile information display, and robotics. In particular, many previous studies have reported flexible and highly sensitive pressure sensors. Among them, e-skin devices based on CNT microfibers show wearable and excellent multimodal (pressure, temperature, humidity, and presence of chemicals) sensing capabilities However, the low sensitivity of these devices at high pressures remains a critical issue. Here, we report on highly flexbile and sensitive e-skin devices prepared by carbon nanotube (CNT) microfibers hybridized with Au flowers, which were synthesized by electrochemical methods. First, we controlled the voltage and reaction time in order to optimize the surface morphology of the CNT microfibers. Next, we fabricated capacitive pressure sensors to elucidate the impact of Au flowers on the sensing capability of the CNT microfiber-based pressure sensors, especially in high pressure regimes. The sensors based on CNT microfibers with Au flowers showed fourfold higher sensitivity than did those without the Au flowers, due to the enhanced air traps between the Au flowers. Furthermore, this morphology of CNT microfibers with Au flowers demonstrated satisfactory repeatability and durability under high pressure.

脫毛에 應用되는 神應養眞丹의 效能에 關한 實驗的 硏究

김소영,김중호,채병윤,Kim, So-Yeong,Kim, Jung-Ho,Chae, Byeong-Yun 대한한방안이비인후피부과학회 1991 한방안이비인후피부과학회지 Vol.4 No.1

In order to verify the effect of Sineungyangjin-Dan on alopecia, I experimented the hair regrowth of the normal mice and of the high butter diet-pretreated mice by feeding each group of mice a certain amount of ethanol extract of Sineungyangjin-Dan and water extract and thus obtained the results as follow; 1. The ethanol extract of Sineungyangjin-Dan was proved to promote the hair regrowth of the hair-removed normal mice. 2. 360mg/kg ethanol extract of Sineungyangjin-Dan was proved to have the effect of promoting hair regrowth by restraining the increase of free cholesterol and triglyceride but by helping the increase of free fatty acid in skin. As a result of the above study Sineungyangjin-Dan was proved to have the effect of promoting hair regrowth.

디지털 X-ray 장치 제작 및 영상 처리 알고리즘 구현

김소영,박승우,이동훈,Kim, So-young,Park, Seung-woo,Lee, Dong-hoon 한국융합신호처리학회 2020 융합신호처리학회 논문지 (JISPS) Vol.21 No.4

This study studied scoliosis, one of the most common modern diseases caused by lifestyle patterns of office workers sitting in front of computers all day and modern people who use smart phones frequently. Scoliosis is a typical complication that takes more than 80% of the nation's total population at least once. X-ray are used to test for these complications. X-ray, a non-destructive testing method that allows scoliosis to be easily performed and filmed in various areas such as the chest, abdomen and bone without contrast agents or other instruments. We uses NI DAQ to miniaturize digital X-ray imaging devices and image intensifier in self-shielding housing with Vision Assistant for drawing lines to the top and the bottom of the spine to acquire angles, i.e. curvature in real-time. In this way, the research was conducted to see scoliosis patients and their condition easily and to help rapid treatment for solving the problem of posture correction in modern people.

낙농인 교육 - 소가 웃는 행복한 나라

김소영,Kim, So-Yeong 한국낙농육우협회 2016 낙농·육우 Vol.36 No.1

동이 트기도 전, 어둑어둑한 새벽 인천공항으로 향하는 버스에 몸을 실었다. 어린 아들을 두고 떠나는 걱정되는 마음과 꿈에 그리던 나라로 떠난다는 설레는 마음으로 복잡했다. 그런 마음을 아는지 남편은 아무 걱정 없이 다녀오라는 말을 건네며 인사해 주었다. 12시간 긴 비행을 마치고 드디어 네덜란드 땅을 밟는 순간 차가운 바람이 코끝을 스치며 기분이 상쾌했다. 앞으로의 일정이 기대되는 순간이었다.