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프로바이오틱스 안전성 문제 개선을 위한 안전성 평가방법의 제안
김세정 ( Sejeong Kim ),윤요한 ( Yohan Yoon ),오세종 ( Sejong Oh ) 한국낙농식품응용생물학회(구 한국유가공학회) 2020 Journal of Dairy Science and Biotechnology (JMSB) Vol.38 No.2
Probiotics are actively being studied for their efficacious anticancer, anticholesterol, and antidiabetic properties. As novel probiotic strains are being developed continuously, new strain-specific safety issues may be reported. Therefore, a procedure for the safety evaluation of probiotic strains is needed. In this study, we investigated the current status of domestic and foreign guidelines for the evaluation of safety of probiotics and suggested a general probiotic safety evaluation process. In other countries, the guidelines for probiotic evaluation are provided and managed separately. However, in Korea, general guidelines are provided regarding the use of functional ingredients, and specific guidelines for the use of probiotics are lacking. A review step based on the characteristics of the probiotics has been introduced in the procedure for safety evaluation of probiotics. Additionally, it has been suggested that the safety evaluation process should consider the results of the functional and genomic analysis for strain identification. Moreover, the factors to be evaluated are presented separately for the notified and non-notified strains. The suggested evaluation procedure may ensure the safety of probiotics, thereby promoting enhanced utilization of probiotics as functional products.
한국 여성의 비만과 체형인식왜곡에 따른 유방암 검진율 차이
김세정(Kim, Sejeong),김희승(Kim, Hee-Seung),김혜진(Kim, Hye-Jin) 기초간호학회 2018 Journal of korean biological nursing science Vol.20 No.3
Purpose: This study was performed to elucidate whether the obesity or body image is a barrier to breast screening compliance in Korean women. Methods: We included 54,017 women aged between 35 to 70 years from the Korea Community Health Survey (KCHS) 2014 dataset. To identify whether a mutual relationship exists between weight perceptions and breast cancer screening rates, the participants were divided into three groups according to the level of concordance between Body Mass Index (BMI) and a subjective body image. Descriptive analyses, a chi-square test, and multivariate logistic regression analyses were performed. Results: After covariate adjustment, the screening rate of the overweight group was 1.09 times higher than the normal weight group (odds ratio [OR], 1.09; confidence interval [CI], 0.00-0.16; p=.038) and the severe obesity group was 1.20 times lower (OR, 0.83; CI, -0.36-0.00; p=.047). Weight misperception also had a significant influence on breast cancer screening. Especially, The overweight distortion group was less likely to undergo breast cancer screening (OR, 0.93; CI, -0.15-0.00; p=.037). Conclusion: Obesity and weight misperceptions are associated with lower compliance with breast cancer screening guidelines.