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Phalloides 증후군에서 혈역학적 보조를 위해 T-PLS를 사용한 1례
김성춘,김규석,서길준,Kim, Seong-Chun,Kim, Kyu-Seok,Suh, Gil-Joon 대한임상독성학회 2004 대한임상독성학회지 Vol.2 No.2
Phalloides syndrome has usually occurred after incidental mushroom ingestion. It is sometimes difficult to differentiate toxic mushrooms from edible ones, especially in lay person because of their morphological similarities. In Korea, Amanita virosa and Amanita subjunquillea have been reported as a cause of fulminant hepatic failure in mushroom poisoning (phalloides syndrome). We report a case of phalloides syndrome who came to death with fulminant hepatic failure even though we planned liver transplantation and used T-PLS(R) (Twin Pulse Life Support) for hemodynamic support while waiting for the donor.
백서의 패혈증 모델에서 시간에 따른 폐조직에서의 Inducible Nitric Oxide Synthase 발현
김중희 ( Joong Hee Kim ),김성춘 ( Seong Chun Kim ),권운용 ( Woon Yong Kwon ),서길준 ( Gil Joon Suh ),윤여규 ( Yeo Kyu Youn ) 대한외상학회 2008 大韓外傷學會誌 Vol.21 No.2
Purpose: Many studies on the time course of inducible nitric oxide synthase (iNOS) gene expression have been performed in the LPS (Lipopolysaccharide)-induced endotoxemic model, but there have been few experimental approaches to continuous peritonitis-induced sepsis model. We conducted this study to establish basic data for future sepsis-related research by investigating the time course of iNOS gene expression and the relationship with the production of inflammatory mediators in the early sepsis model induced by cecal ligation and puncture (CLP). Methods: Male Sprague-Dawley rats were operated on by sing the CLP method to induce of peritonitis; and then, they were sacrificed and samples of blood and lung tissues were obtained at various times (1,2,3,6,9 and 12 h after CLP). We observed the expression of iNOS mRNA from lung tissues and measured the synthesis of nitric oxide, IL-1β, and TNF-αfrom the blood. Results: iNOS mRNA began to be expressed at 3 h and was maintained untill 12 h after CLP. The nitric oxide concentration was increased significantly at 6 h, reached its peak level at 9 h, and maintained a plateau untill 12 h after CLP. TNF-αbegan to be detected at 3 h, increased gradually, and decreased steeply from 9 h after CLP. IL-1βshowed its peak level at 6 h after CLP, and tended to decrease without significance. Conclusion: We observed that the iNOS gene was expressed later in peritonitis-induced sepsis than in LPSinduced sepsis. Nitric oxide and key inflammatory mediators were also expressed later in peritonitis-induced sepsis than in LPS-induced sepsis. (J Korean Soc Traumatol 2008;21:120-127)
서윤석 ( Yun Suhk Suh ),김성춘 ( Seong Chun Kim ),라환도 ( Hwan Do Ra ),한호성 ( Ho Seong Han ) 대한외상학회 2006 大韓外傷學會誌 Vol.19 No.2
We report a case of celiac artery dissection after abdominal blunt trauma. A 29-year-old man visited the emergency room for acute left periumbilical pain after abdominal blunt trauma from his child. Computed tomography showed a wedge-shaped splenic infarction with splenic artery thrombus. He was hospitalized for careful observation, and after two days, follow-up computed tomographic angiography showed a progressed celiac artery dissection that involved common hepatic artery and an increased extent of splenic infarction. He underwent conventional angiography, and a self-expandable stent was placed between the celiac axis and the common hepatic artery. After two days, follow-up computed tomographic angiography showed good hepatic arterial blood flow via the stent and no progression of splenic infarction. After ten days, he was discharged without complications. (J Korean Soc Traumatol 2006;19:196-200)