Factors Affecting College Students' Teeth Whitening Preference

김선예 한국컴퓨터정보학회 2023 韓國컴퓨터情報學會論文誌 Vol.28 No.10

This study investigated tooth whitening preferences among college students, evaluating their knowledge, satisfaction, aesthetic criteria, and preferences, while identifying influencing factors. Using a 28-item questionnaire covering general, tooth whitening knowledge, satisfaction, aesthetic criteria, and preference questions, 175 participants surveyed from June 7th to 10th, 2022, underwent analysis. Descriptive statistics, t-tests, analysis of variance, and regression analysis were applied. Results showed tooth whitening knowledge scored 2.90 out of 5 points, satisfaction 2.97, aesthetic criteria 3.59, and preferences 3.28. Tooth whitening knowledge was higher among female and health-related major students, while satisfaction was greater among males, non-health-related majors, and those without cosmetic procedures. Aesthetic criteria were stronger in participants with higher allowances and cosmetic procedures experience. No significant tooth whitening preference differences were found based on general characteristics. Regression analysis revealed significant impact of aesthetic criteria on tooth whitening preferences (β=0.252).

Hypoxia-inducible Factor-1에 의한 Aromatic L-amino Acid Decarboxylase의 발현 증가

김선예,안국희,김자은,박찬,정주원 대한암예방학회 2008 Journal of cancer prevention Vol.13 No.4

Hypoxia-inducible factor (HIF-1) is an oxygen-dependent transcriptional activator, which plays crucial roles in the angiogenesis of tumors and mammalian development. HIF-1 acts as a master regulator of numerous hypoxia-inducible genes under hypoxic conditions. The target genes of HIF-1 are especially related to angiogenesis, cell proliferation/survival, and glucose/iron metabolism. Moreover, it was reported that the activation of HIF-1α is closely associated with a variety of tumors and oncogenic pathways. Perinatal hypoxia is known to induce long-lasting changes in the central dopaminergic system. In order to understand the cellular mechanism of these changes, we investigated the effects of hypoxia on the levels of genes related with dopamine synthesis and transport. We found mRNA for aromatic L-amino acid decarboxylase (AADC) was increased by hypoxic exposure. This gene was also upregulated by the transfection with HIF-1α. These results indicated that the hypoxic induction of AADC was mediated by HIF-1 transcription factor.

신경아세포종 유래 세포주에서 저산소에 의한 Vesicular Monoamine Transporter 2 발현 유도 현상

김선예,김자은,박찬,정주원 대한암예방학회 2008 Journal of cancer prevention Vol.13 No.4

The vesicular monoamine transporter 2 (VMAT2) is an integral membrane protein that acts to transport neurotransmitters including dopamine, norepinephrine, serotonin, and histamine from cellular cytosol into synaptic vesicles. In the central nervous system, VMAT2 is the only transporter that moves cytoplasmic dopamine into synaptic vesicles. Preventing the oxidation of dopamine may be a strategy for treating Parkinson’s disease. In this study, we report that hypoxia potentially increased the expression of VMAT2 in SH-SH5Y human neuroblastoma cells. In SH-SY5Y cells, hypoxia-inducible factor-1α was stabilized by exposure to hypoxia with the same patterns in various solid tumor cells. Taken together, these results demonstrated that VMAT2 can be regulated by hypoxic stress in human neuroblastoma cells.

Risk of dementia according to the severity of chronic periodontitis in Korea: a nationwide retrospective cohort study

김선예,Son Minkook,김유린,강현경 한국역학회 2022 Epidemiology and Health Vol.44 No.-

OBJECTIVES: We investigated the risk of dementia in older adults with chronic periodontitis according to the severity of periodontitis. METHODS: Data on patients with chronic periodontitis were extracted from the National Health Insurance Service-Senior cohort database from 2002 to 2014. Among 52,728 subjects eligible for inclusion, 11,953 subjects had newly diagnosed mild chronic periodontitis (MCP), and 40,775 subjects had newly diagnosed severe chronic periodontitis (SCP). Two 1:1 propensity score matched cohorts were created with 8,624 patients each in the MCP and SCP groups. To analyze the risk of dementia, a Cox proportional-hazard model was used to calculate hazard ratios with 95% confidence intervals (CIs). RESULTS: In the Kaplan-Meier curve, the disease-free probability was significantly lower in the SCP group than in the MCP group (p for log-rank= 0.001). In the multivariable-adjusted model, the HR for the occurrence of dementia in the SCP group compared to the MCP group was 1.15 (95% CI, 1.04 to 1.27; p= 0.009). A subgroup analysis revealed a significant association between dementia and the severity of periodontitis, especially in subjects who were male, aged ≥ 70 years, and had comorbidities. CONCLUSIONS: Reducing the severity of chronic periodontitis can help to reduce the risk of dementia. Therefore, it is necessary to aggressively conduct early dementia-prevention programs for males under the age of 70 that include dental health to prevent the progression of periodontitis from mild to severe.

의무병과정 교육생의 기본심폐소생술에 관한 교육 전·후 지식수준 및 태도

김선예,박안숙,윤지성,조혜경,홍송희,조병준,문태영 한국자료분석학회 2011 Journal of the Korean Data Analysis Society Vol.13 No.4

Purpose : This study was performed to provide a guidance for basic life support training strategies for medic through the analysis of medic trainees' characteristics, knowledge and attitudes concerning cardiopulmonary resuscitation. Method : This is a descriptive cross-sectional survey study of the medic trainees belonged to school of military medicine for 4wks. One group pretest-posttest paired with same questionaire survey was designed. t-test analysis was used to determine any significant variate in frequency, percentage, means. A prior significant level(琚) was set at 0.05. Results : The 336 responders (responders rate 100%) are 19∼20years old male. They have experience with emergent situation was 17%. Mean score of experience with cardiopulmonary resuscitation training before listed school of military medicine was 78%. Attitude score was higher posttest (35.27±4.67) than previous cardiopulmonary resuscitation training (36.53±4.81) with significant different (p<0.05). Related factors of blockage to cardiopulmonary resuscitation was concern make patient worse that not quite enough to cardiopulmonary resuscitation (48.2→38.4) and considering responsibility for side effect (28.9→32.4). The score of posttest knowledge was higher than pretest significantly (6.81±1.11→7.07±1.03) (p<.001). Conclusion : The result of this study suggest that medic trainee should be evaluated by the skill guiders and methodological approach for basic life support training quality. 본 연구는 전시 및 야전의 응급상황에서 응급의료를 책임지고 있는 의무병의 기본심폐소생술에 대한 지식과 태도에 관한 차이를 교육 전⋅후로 살펴보고자 함이다. 이를 위해 의무병으로 분류된 336명을 대상으로 하였다. 수집된 자료는 신뢰도 검사, 빈도분석, t-검정을 실시하였다. 연구 결과는 대상자들이 과거 응급상황에 대한 경험에서 아무런 조취를 하지 못하고 다른 사람이 응급처치 하는 것을 구경한 대상자가 59.6%로 가장 많았으며, 교육 경험 중에서 78.2%가 입대 전 기본심폐소생술 받은 경험이 있으며, 6개월 이내가 14.9%, 1년 반 이내가 88.2%로 나타났다. 교육 시 개선해야 할 사항으로는 다양한 시청각 교재의 활용이 가장 높았으며, 교육 전⋅후 태도의 차이는 35.27점에서 36.53으로 통계적으로 유의하게 증가하였고, 지식수준은 6.81점에서 7.07로 유의하게 증가하였다. 결론적으로 의무병의 기본인명구조 교육의 궁극적인 목표가 전시 및 야전의 응급상황에서 신속하게 판단하여 정확한 방법으로 기본심폐소생술을 수행하는 것이라면, 지식뿐만 아니라 자신감을 가지고 기본심폐소생술을 수행하는데 필요한 실기 중심의 교육프로그램 개발이 절실히 요구된다는 것이다.

Study of water drowning death patients on clinical care and prevention

김선예,조병준,고장식 한국디지털정책학회 2016 디지털융복합연구 Vol.14 No.5

The purpose of this study was to investigate drowning death patients on clinical care and prevention. Drowning accidents that occurred in the Republic of Korea were identified by using the Emergency Activity Daily Report Data from the National Emergency Management Agency (NEMA). The age of drowning accidents was 20-29 years (25.4%). Drowning cases for the months of August was 17.6%. The main circumstance involved in the drowning cases was swimming (45.0%). Half of swimming incidents related the drowning accidents of people attempting to save a life of a family member or friend from the water. The most common location was at a lake or reservoir (40.2%). Drowning is a main cause of accidents in the Republic of Korea. Preventive strategies that may be beneficial for persons contain life jackets or life rings supply, upgrading swimming ability, placing lifeguards based on public education activities.

The risk of stroke according to statin medication compliance in older people with chronic periodontitis: an analysis using the Korea National Health Insurance Service-Senior Cohort Database

김선예,Son Minkook,김유린 한국역학회 2022 Epidemiology and Health Vol.44 No.-

OBJECTIVES: We investigated the risk of stroke according to statin medication compliance in older people with chronic periodontitis. METHODS: Chronic periodontitis patients were extracted from the National Health Insurance Service-Senior Cohort Database from 2002 to 2014. Among 255,056 chronic periodontitis patients, 41,412 patients with statin prescriptions for 28 days or more were included. The study population was divided into the top 25% of medication compliance group (TSG) and the lower 25% of medication compliance group (BSG). After 1:1 propensity score matching was performed, the final number of patients in the BSG and TSG was 6,172 each. To analyze the risk of stroke, a Cox proportional hazard model was performed to calculate hazard ratios (HRs) and 95% confidence intervals (95% CIs) after adjusting for age, sex, income level, hypertension, diabetes, and Charlson comorbidity index. RESULTS: In the Kaplan-Meier curve, the disease-free probability was prominently lower in the BSG than in the TSG (p for log-rank= 0.001). The HR in the multivariable-adjusted model for stroke occurrence in the TSG compared to the BSG was 0.79 (95% CI, 0.67 to 0.92; p= 0.002). Subgroup analyses showed significant associations between compliance to statin medication and stroke, especially in female, people 85 years or older, and patients with comorbidities. CONCLUSIONS: Increasing compliance to statins may reduce stroke risk in older adults with chronic periodontitis. Therefore, in order to increase medication compliance among older people with chronic periodontitis, it is necessary for medical staff to make efforts to provide effective medication guidance.

CXCR4 as a Marker of Cancer Stem Cell in A549 Lung Cancer Cells with Epithelial to Mesenchymal Transition (초)

김선예,노진경,최윤정,최유리,박명진,김혜련,김철현 대한결핵 및 호흡기학회 2010 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.110 No.-

죽음준비교육이 요양보호사의 DNR에 대한 태도, 피로, 수면의 질에 미치는 효과

김선예(Seon-Rye Kim),오청욱(Chung-Uk Oh),박윤진(Yoon-Jin Park) 한국산학기술학회 2016 한국산학기술학회논문지 Vol.17 No.10

본 연구의 목적은 요양보호사 대상의 죽음준비교육이 요양보호사의 DNR에 대한 태도, 피로, 수면의 질에 미치는 효과를 파악하는 데에 있다. 연구의 설계는 비동등 대조군 실험 연구이다. 본 연구는 총청도 J시의 재가노인장기요양서비스 기관에서 2016년 02월 15일부터 5월 30일까지 시행하였다. 본 연구에 대상자는 참여를 동의한 재가노인장기요양서비스기관의 요양보호사 총 43명을 대상으로 하였다. 실험군과 대조군은 각각 21, 22 명씩 무작위로 나누어 배정하였다. 실험군(n=21)을 대상으로 매 회 2시간, 주 1회, 8주간에 걸쳐 죽음준비교육을 실시하였다. 실험 처치 효과는 DNR에 대한 태도, 피로, 수면의 질의 변화를 8주간의 중재 전, 후에 구조화된 설문지를 통하여 측정하였다. 자료의 분석은 t-, chi-square, Fisher Exactand paired t-tests를 사용하였다. 8주간의 중재 후 실험군의 DNR에 대한 태도 (P<.001), 수면의 질(P<.001)이 유의하게 증가된 반면, 피로(P<.030)는 유의하게 감소되었다. 죽음준비교육 프로그램은 요양보호사에게 효과적인 간호 중재로 보인다. 그러므로, 죽음준비교육 프로그램의 현장 적용 가능성을 고려할 수 있겠다. The aim of this study was to investigate the effects of death education on the attitude toward DNR, fatigue, and quality of sleep for generic care worker. This study followed a nonequivalent control group and a non-synchronized design. This study was performed in a visiting generic care service institution in J city, Chung-Cheong province, Korea between February 15 to May 30, 2016. The study included 43 participants who agreed to participate in this study. They were randomly divided into two groups: 21 participants in the experimental group and 22 in the control group. Participants in the experimental group received death education 2 hours per day, once a week, for a duration of greater than 8 weeks. The effect of treatment was measured using a structured questionnaire on the attitude toward DNR, fatigue, and quality of sleep before and after 8 weeks of intervention. Data were analyzed using t-, chi-square, Fisher Exact- and paired t-tests. The experimental group showed a significantly increased attitude toward DNR (p=0.001) and quality of sleep (P<0.001), whereas significantly decreased attitude toward fatigue (p=0.030) than the control group after 8 weeks of intervention. The death education program was shown to be an effective nursing intervention for generic care workers. Therefore, we can consider the possibility of incorporating death education in the nursing program.

질병관리청의 데이터를 이용한 COVID-19 확진자의 사망에 대한 영향요인과 혈액변수의 타당도

김유린,남설희,김선예 한국컴퓨터정보학회 2020 韓國컴퓨터情報學會論文誌 Vol.25 No.11

In this paper, we propose impact factors and validity of blood variables on death of COVID-19 patients. The clinical-epidemiological data of 5628 COVID-19 patients, provided from Korea Disease Control and Prevention Agency as day of 30th April 2020, were used. As results, impact factors of death were dementia, older age, high lymphocyte, cancer, dyspnea, COPD, change of consciousness, heart disease, high platelets, abnormal diastolic pressure and fever. The validities of blood variables for death were high in the order of lymphocyte, hemoglobin, hematocrit, platelet and WBC. Therefore, risk factors such as initial clinical characteristics, underlying disease and blood test results, could be regarded for efficient management of COVID-19 patients. 본 연구에서 우리는 COVID-19의 사망에 대한 영향요인과 혈액변수의 타당도를 제안하였다. 이연구를 위하여 질병관리본부 중앙방역대책본부에서 제공하는 2020년 4월 30일까지 격리해제되었거나 사망한 COVID-19확진자 5628명의 임상역학정보를 활용하였으며, 자료는 R 3.4.1을 사용하여분석하였다. 분석결과, 사망에 대한 위험요인으로 치매(HR 7.03), 많은 나이(HR 5.39), 높은 림프구(HR 4.66), 암(HR 4.27), 호흡곤란(HR 3.25), 만성폐쇄성 폐질환(HR 3.22), 의식변화(HR 3.13), 심장질환(HR 2.24), 높은 혈소판(HR 2.14), 비정상 이완기 혈압(HR 2.02), 열(HR 1.69)이 확인되었다. 사망에 대한 혈액검사의 타당도는 림프구, 헤모글로빈, 헤마토크리트, 혈소판, 백혈구 순으로 정확도가 높았다. 그러므로 COVID-19 환자를 치료할 때 사망의 위험요인으로 확인된 초기 임상적 특징및 기저질환, 혈액검사의 소견을 고려하여 보다 효율적인 관리가 가능하도록 해야 할 것이다.