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Nude Mouse 에 이종이식한 두경부 편평상피세포암의 분화에 대한 Retinoids의 작용
김상윤,유증주,유근식,주준범,최두영,남순열,Kim, Sang-Yoon,Yoo, Seung-Joo,Yoo, Keun-Sik,Joo, Joon-Bum,Choi, Doo-Yung,Nam, Soon-Yuhl 대한기관식도과학회 1999 大韓氣管食道科學會誌 Vol.5 No.2
Objectives : To analyze the effect of retinoids on the differentiation in HNSCC xenografts. Materials and Methods : RA (20mg/kg) or 13-cis-RA (60mg/kg) was orally administered once in a day for 30 days in the xenograft model we prepared using athymic nude mice with AMCHN-4 and -6. We carried out H & E staining and immunohistochemical staining with the monoclonal antibody against involucrin and cytokeratin 10. Results : Both RA and 13-cis-RA were found to suppress the differentiation of AMC-HN-4. Interestingly, RA enhanced the differentiation of AMC-HN-6, although 13-cis RA did not exhibit any effect on the differentiation. These results suggest that in vivo effect of retinoids on the HNSCC growth and differentiation might be various. Retinoids-induced P450 in AMC-HN-6 might be one of the mechanisms to explain the reason why the retinoids exhibit various functions in the HNSCC.
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Top형 스핀밸브구조에서 반강자성체 두께 변화에 따른 자기적 특성 연구
김상윤,고훈,최경호,이창우,김지원,조순철,Kim, Sang-Yoon,Ko, Hoon,Choi, Kyoung-Ho,Lee, Chang-Woo,Kim, Ji-Won,Jo, Soon-Chul 한국자기학회 2007 한국자기학회지 Vol.17 No.1
In this research, magnetic properties of spin valve structures using IrMn layers as antiferromagnetic were studied depending on the thickness of the pinned layer. The spin valve structure was Si substrate/$SiO_2(2,000\;{\AA})/Mo(17\;{\AA})NiFe(21\;{\AA})/CoFe(28\;{\AA})/Cu(22\;{\AA})/CoFe(18\;{\AA})/IrMn(t\;{\AA})/Ta(25\;{\AA})$. Also, Mo film was deposited on Si substrates and the thermal annealing effect was analyzed. The resistivity of the Mo film was increased as an annealing temperature was increased up to $600^{\circ}C$. The variations of MR ratio were related with magnetic exchange coupling field of the spin valve structures for various IrMn pinned layer thickness up to 130 ${\AA}$. MR ratio and $H_{ex}$ of spin valves was about 9.05% and 277.5 Oe when the thickness of the IrMn pinned layer was $32.5\;{\AA}(t=32.5\;{\AA})$. It was increased to 9.65% and 337.5 Oe for $t=65\;{\AA}$. For $t=97.5\;{\AA}$, the MR ratio and Hex decreased to 8.2% and 285 Oe, and further decrease was observed up to $t=130\;{\AA}$.
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김상윤,박대규,전두환,박명규,Kim, Sang-Yoon,Park, Dae-Kyu,Chun, Du-Hwan,Park, Myung-Kyu 한국전산구조공학회 2008 한국전산구조공학회논문집 Vol.21 No.5
While high speed / precision investigating for maximization of Textile Machinery business is requesting a machine which has highly endurance, stability and reliance abilities following customer request. In this research, load volume that gives influence on loom is measured and analyzed for water jet loom in real operation time to driving system adhered torque sensor to each a module. As well, measurement and analysis technology are developed about torque and vibration of driving systems for textile machinery by comparing dynamical analysis of water jet loom with gained result, basic materials about development of high value added textile machinery which has endurance and stability are presented.
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금속분말 사출성형법을 이용한 자수기용 로터리 훅 제조 연구
김상윤,박시우,정일섭,정재옥,조규상,Kim, Sang Yoon,Park, Si Woo,Chung, Ilsup,Jung, Jae Ok,Cho, Kyu Sang 한국섬유공학회 2017 한국섬유공학회지 Vol.54 No.4
Embroidery process is the last stage of manufacturing textile products by sewing thread mechanism. The rotary hook that is manufactured by several stages of precision machining is a key part of completing the knot in embroidery. The rotary hook was manufactured by applying MIM (metal injection molding) techniques techniques, which combine the advantages of injection molding and metal powder sintering technologies, to obtain high productivity and dimensional accuracy. The sintering of injection product was performed at a temperature between $600^{\circ}C$ and $1,275^{\circ}C$ in an atmosphere of Argon with a relative density of 99% at $1,275^{\circ}C$ to 99% at the sintering temperature. A product with a hardness of 700 HV was manufactured by heat treatment. All the prescribed patterns were completed without obtaining a prescribed pattern for the developed prototype. Further, the wear test of the hook body carried out using gold thread also showed a similar decrease in size compared to that of the existing product. In this study, the manufacturing method was developed by applying MIM techniques to replace the manufacturing process of the rapidly executed rotary hook that entails various stages of machining. The developed manufacturing process is expected to boost the competitiveness of Korea's embroidery industry by replacing imports and contributing to more than 30% cost savings.
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