말티톨 첨가 흑마늘잼의 이화학적 특성 및 항산화성

김민지,김민희,김효진,이지연,김혜란,유보람,양기현,김미리,Kim, Min-Ji,Kim, Min-Hee,Kim, Hyo-Jin,Lee, Ji-Yeon,Kim, Hye-Ran,You, Bo-Ram,Yang, Ki-Hyun,Kim, Mee-Ree 한국식품조리과학회 2010 한국식품조리과학회지 Vol.26 No.6

흑마늘로 잼을 만들어 품질특성을 알아본 결과, pH 및 산도는 MTS 첨가군이 pH가 가장 높았으며 산도는 대조군이 가장 높았다. 환원당 함량은 MT 첨가군, MTS 첨가군 순으로 환원당 함량이 높았다. 점도는 MT 첨가군, MTS 첨가군 순이었고, 대조군은 가장 낮았다. 색도는 명도는 MT군이 가장 높았으며 적색도는 대조군이 말티톨시럽을 첨가한군에 비하여 높았다. 황색도는 MTS군이 가장 높았다. 기계적인 조직감 측정결과, 경도와 부착성은 MT 첨가군이 가장 높고 그다음이 MTS, 대조군의 순이었다. 탄력성과 응집성은 처리간에 유의적인 차이가 없었다. DPPH radical 및 hydroxy radical 소거능 측정에 의한 항산화능은 MT군이(DPPH $IC_{50}$: 49.63 mg/g, hydroxy radical $IC_{50}$: 27.24 mg/g) 가장 높았고 그다음이 MTS군이었으며 대조군은 가장 낮았다. 총페놀함량은 MT군이 가장 높고, 그다음이 MTS군, 대조군의 순으로 항산화능 결과와 일치하였다. 관능검사결과, 마늘냄새는 MT군과 MTS군이 낮았으며, 기호도 검사에서 향미와 전반적인 수용도는 MTS군이 6.9점 및 6.6점으로 가장 높은 점수를 받았으며, 설탕군은 5.8점으로 말티톨군의 5.3점과 유사하였다. 제품구입의사는 MTS군이 6.8점으로 가장 높은 점수를 받았으며, MT군은 낮은 점수를 받았다. 이와 같은 결과를 종합해보면 잼 제조시 설탕을 말티톨로 대체시 50% 정도만 대체하는 것이 관능적으로 가장 좋다고 사료된다. The antioxidant activities and quality characteristics of jams containing maltitol substituted for sucrose(sucrose, maltitol syrup(MT), and MTS(sucrose 50%+MT 50%)) were evaluated. The endpoint of jam preparation was determined to be 64 $^{\circ}Brix$. The pH was the highest in MTS among all treatments. The reducing sugar content and viscosity were the highest in MT, and second highest in MTS. Lightness(L value) of Hunter color system was the highest in MT, whereas yellowness(b value) was the highest in MTS. Hardness and cohesiveness of textural properties were the highest in MT. Antioxidant activities were the highest in MT, which also had the lowest $IC_{50}$ values(49.63 mg/g for DPPH and 27.24 mg/g for hydroxyl radical scavenging activity). Total phenol content was highest in MT among all treatments. Flavor and overall acceptance scores of MTS were the highest among all treatments. Based on these results, it was suggested that half-substitution of sucrose with maltitol is the most appropriate for attaining favorable physicochemical and antioxidative properties during black garlic jam preparation.

간호대학생의 카페인 음료섭취와 학습 집중력, 수면의 질과의 관계

박진아(Park jin ah),김진희(Kim jinhee),김나윤(Kim nayoon),김민지A(Kim minjiA),김민지B(Kim minjiB),김은지(Kim eunji),김수정(Kim sujeong),박진아(Park jina) 한국콘텐츠학회 2016 한국콘텐츠학회 종합학술대회 논문집 Vol.2016 No.5

정신과 의사와 비정신과 의사의 항우울제 처방에 대한 연구 : 건강보험심사평가원 청구 데이터 중심으로

김민지,김남우,신다운,이상진,박형근,김혜영,양보람,안용민,Kim, Min Ji,Kim, Namwoo,Shin, Daun,Rhee, Sang Jin,Park, C. Hyung Keun,Kim, Hyeyoung,Yang, Boram,Ahn, Yong Min 대한생물정신의학회 2019 생물정신의학 Vol.26 No.2

Antidepressants are widely used to treat depression in Korea, however, only a few studies have focused on the provider of the treatment. The aim of the study is to compare the differences between patients who were prescribed antidepressants by psychiatrists and those who were prescribed antidepressants by non-psychiatrists in South Korea. Patients with a diagnosis of depressive disorder who had been newly prescribed antidepressants in 2012 were selected from the Health Insurance Review and Assessment Service database. They were classified into two groups depending on whether they received the antidepressant prescription from a psychiatrist or non-psychiatrist. Sociodemographic, clinical, and depression related cost has been investigated. Treatment resistant depression, which is defined as a failure of two antidepressant regimens to alleviate symptoms, was also investigated. Prescription adequacy was assessed based on whether a regimen was maintained for at least 4 weeks. Among the 834694 patients with pharmaceutically treated depression (PTD) examined in this study, 326122 (39.1%) were treated by psychiatrists. Patients who were treated by psychiatrists were younger and had more psychiatric comorbidities than those treated by non-psychiatrists. They had longer PTD duration (229.3 days vs. 103.0 days, p < 0.05) and a larger proportion of treatment resistant depression (9.3% of PTD) when compared to those patients treated by non-psychiatrists. The patients treated by psychiatrists had a smaller proportion of inadequate antidepressant use compared to those patients in the non-psychiatrist group (44.5% vs. 65.1%, p < 0.05). The costs related to depression corrected with PTD duration were higher in the non-psychiatrist group (32214 won vs. 56001 won, p < 0.05). Patients who receive antidepressants from psychiatrists are patients with more severe, treatment-resistant depression. Psychiatrists prescribe antidepressants more adequately and cost- effectively than non-psychiatrists.

P3HT:PCBM 층 내 분산 가능한 금속 나노입자의 제조 및 이를 포함한 고분자 태양전지 소자의 특성에 관한 연구

김민지,최규채,김영국,김양도,백연경,Kim, Min-Ji,Choi, Gyu-Chae,Kim, Young-Kuk,Kim, Yang-Do,Baek, Youn-Kyoung 한국분말야금학회 2014 한국분말재료학회지 (KPMI) Vol.21 No.3

In this study, we prepare polymer solar cells incorporating organic ligand-modified Ag nanoparticles (O-AgNPs) highly dispersed in the P3HT:PCBM layer. Ag nanoparticles decorated with water-dispersible ligands (WAgNPs) were also utilized as a control sample. The existence of the ligands on the Ag surface was confirmed by FT-IR spectra. Metal nanoparticles with different surface chemistries exhibited different dispersion tendencies. O-AgNPs were highly dispersed even at high concentrations, whereas W-AgNPs exhibited significant aggregation in the polymer layer. Both dispersion and blending concentration of the Ag nanoparticles in P3HT:PCBM matrix had critical effects on the device performance as well as light absorption. The significant changes in short-circuit current density ($J_{SC}$) of the solar cells seemed to be related to the change in the polymer morphology according to the concentration of AgNPs introduced. These findings suggested the importance of uniform dispersion of plasmonic metal nanoparticles and their blending concentration conditions in order to boost the solar cell performance.

이매방 살풀이춤의 ‘여형화(女形化)’에 대한 논의

김기화 ( Kim Ki-hwa ) 한국무용연구학회 2020 한국무용연구 Vol.38 No.1

우리는 이매방의 춤을 이야기할 때 ‘아름답다’, ‘교태적이다’, ‘농염하다’라고 표현한다. 이러한 수사(修辭)는 그의 춤이 다분히 여성적인 속성을 갖고 있기 때문에 붙여진 것이다. 본 연구는 이매방의 살풀이춤이 여형화의 양식체계로 구축되어 있음을 논의하였다. 춤에서 ‘여형화’란 남성이 여성의 모습으로 춤을 추는 형식, 혹은 양식이라고 할수 있다. 이매방의 춤은 다음과 같은 여형화의 특성을 보인다. 첫째, 이매방의 살풀이춤은 경극의 ‘화단’이나 가부키의 ‘게이세이’와 같이 화려하고 교태스런 배역 특성을 보인다. 둘째, 살풀이춤의 복식은 남성과 여성의 구분을 두고 있으되 상당히 장식적인 여성성을 지향하고 있다. 셋째, 이매방의 양성 지향적인 성 정체성은 탐미적인 미의식으로 확장되어 여형화 된 춤 양식 체계로 환원되었다. 넷째, 이매방 살풀이춤의 기법은 가공된 여성의 신체상을 기반으로 구축되었다. 즉, 응축된 근육의 밀도 높은 작용을 통해 신체를 ‘축소’하거나 ‘왜곡’하여 관능적이고 요염한 여성성을 신체상으로 구현하여 춤에 반영하였다. 이상으로 미루어 이매방 살풀이춤은 남성이 추는 여성의 춤, 혹은 기방춤을 전형 특성의 하나로 구축하고 있다고 하겠다. When we talk about Lee Mae-bang's Salpul-i chum, we use the expressions ‘beautiful’, ‘exciting’, and ‘congested’. This knowledge was attached because his dance has a feminine attribute. This study discussed that Lee Mae-bang's Salpul-i chum is constructed as Yeohyeonghwa's aquaculture system. First, Lee Mae-bang's Salpul-i chum exhibits gorgeous and cunning character, such as Peking Opera's 'Huā dàn' or Kabuki's 'Keisei'. In dance[chum], ‘Yeohyeonghwa’ can be said to be a form or style in which men dance in the form of women. Lee Mae-bang's dance shows the following characteristics of Yeohyeonghwa. Second, Salpul-i chum's costumes differentiate between men and women, but aim for a highly decorative femininity. Third, Lee Mae-bang's bisexual sexual identity has been stylized into a feminine attitude through aesthetic pursuit. Fourth, Lee Mae-bang Salpul-i chum's technique expresses the processed female body image. In other words, Salpul-i chum expresses the body of a sensual and fascinating woman by 'shrinking' or 'distorting' the body through the dense action of condensed muscles. In this regard, Lee Mae-bang is said to be constructing a male dance or gibangchum as one of the characteristics of Jeonhyeong[original form].

이변량 강우 빈도분석과 강우-유출 모형에 기반한 설계 홍수량 산정 방안

김민지,박경운,김석우,김태웅,Kim, Min Ji,Park, Kyung Woon,Kim, Seok-Woo,Kim, Tae-Woong 한국수자원학회 2022 한국수자원학회논문집 Vol.55 No.10

Due to the lack of flood data, the water engineering practice calculates the design flood using rainfall frequency analysis and rainfall-runoff model. However, the rainfall frequency analysis for arbitrary duration does not reflect the regional characteristics of the duration and amount of storm event. This study proposed a practical method to calculate the design flood in a watershed considering the characteristics of storm event, based on the bivariate rainfall frequency analysis. After extracting independent storm events for the Pyeongchang River basin and the upper Namhangang River basin, we performed the bivariate rainfall frequency analysis to determine the design storm events of various return periods, and calculated the design floods using the HEC-1 model. We compared the design floods based on the bivariate rainfall frequency analysis (DF_BRFA) with those estimated by the flood frequency analysis (DF_FFA), and those estimated by the HEC-1 with the univariate rainfall frequency analysis (DF_URFA). In the case of the Pyeongchang River basin, except for the 100-year flood, the average error of the DF_BRFA was 11.6%, which was the closest to the DF_FFA. In the case of the Namhangang River basin, the average error of the DF_BRFA was about 10%, which was the most similar to the DF_FFA. As the return period increased, the DF_URFA was calculated to be much larger than the DF_FFA, whereas the BRFA produced smaller average error in the design flood than the URFA. When the proposed method is used to calculate design flood in an ungauged watershed, it is expected that the estimated design flood might be close to the actual DF_FFA. Thus, the design of the hydrological structures and water resource plans can be carried out economically and reasonably.

마이크로파 정제에 의한 액정방사용 단일벽 탄소나노튜브의 제조 및 특성

김민지,이동주,구본철,유기현,김대윤,김남동,Kim, Min Ji,Lee, Dongju,Ku, Bon-cheol,Ryu, Ki-Hyun,Kim, Dae-Yoon,Kim, Nam Dong 한국섬유공학회 2021 한국섬유공학회지 Vol.58 No.3

Carbon nanotube fibers (CNTFs) have attracted wide attention owing to their exceptional lightness, electrical conductivity, and mechanical flexibility that make them potential components for applications including carbon composites, nanoelectronics, and optics. CNTFs have been successfully fabricated from carbon nanotubes (CNTs) by liquid-crystal spinning. This spinning method requires low-defect CNTs to form a liquid crystalline phase for making highly-oriented CNTFs. In this study, we conducted microwave purification to effectively remove impurities from CNTs, such as residual metallic catalyst and carbon-based impurities, that are formed during CNT synthesis. We fabricated single-walled carbon nanotube fibers (SWCNTFs) using liquid-crystal spinning purified single-walled carbon nanotubes (SWCNTs) to examine the effect of SWCNTs on the liquid crystal phase and resultant fibers. In conclusion, this method removed impurities from SWCNTs and increased the oxygen-containing functional groups in the SWCNTs, which are capable of forming a liquid crystal phase, thereby enhancing the mechanical performance of fibers.

HPLC-ICP/MS 와 ICP/MS를 이용한 FAPAS 07187 쌀의 총비소, 무기비소, 카드뮴 측정

노현명 ( Hyun Myung Noh ),김지영 ( Ji Young Kim ),김원일 ( Won Il Kim ),( Anitha Kunhikrishnan ),김민지 ( Min Ji Kim12 ),김경진 ( Gyeong Jin Kim ),박기문 ( Ki Moon Park ),류지혁 ( Ji Hyock Yoo ),김두호 ( Doo Ho Kim ),이영자 ( Y 한국환경농학회 2013 한국환경농학회 학술대회집 Vol.2013 No.-

Metal (loid)s such as environmental contaminants affect food safety. Metal (loid)s exist trace extremely in agriculture products. Therefore it is important to analyze accurately about trace these metals. High resolution techniques and quality controls are needed to analyze these materials. In order to achieve quality results, standardized methods and techniques are required. So ISO(International Organization for Standardization) of laboratory proficiency testing is determination of laboratory testing performance by means of inter-laboratory comparison. The values have been derived as a consensus of a number of laboratories using a variety of methods. Proficiency tests were applied to analyze the metal(loid)s [inorganic arsenic (As), total As and cadmium (Cd)] in powdered rice FAPAS 07187 (Food Analysis Performance Assessment Scheme; February-April 2013). The rice powder sample was extracted with 1% HNO3 for inorganic As for microwave-assisted extraction using water at 95℃ for 90 min and their analysis by HPLC/ICPMS. Also, HNO3 for total As and Cd using microwave-assisted extraction using at 200℃ for 50 mins and analysis by ICP/MS. Validation check was performed for accuracy using CRM (NMIJ CRM 7503-a) for inorganic As, and CRM (IRMM-Rice CRM) for total arsenic and cadmium. The result were satisfactory. FAPAS 07187 the z-scores of inorganic As, total As and Cd in powdered rice were-1.8,-0.9 and 0.2(lzl<2, respectively).

골형성부전증의 착상전 유전진단을 위한 분자유전학적 방법의 조건 확립과 적용

김민지,이형송,최혜원,임천규,조재원,김진영,송인옥,강인수,Kim, Min-Jee,Lee, Hyoung-Song,Choi, Hye-Won,Lim, Chun-Kyu,Cho, Jae-Won,Kim, Jin-Young,Song, In-Ok,Kang, Inn-Soo 대한생식의학회 2008 Clinical and Experimental Reproductive Medicine Vol.35 No.2

목 적: 착상전 유전진단은 환아를 출산할 가능성이 높은 부부들에게 정상아의 출산 기회를 제공해주는 보조생식술의 하나로서 널리 시행되고 있다. 골형성부전증은 상염색체 우성 유전질환으로서 뼈와 피부를 구성하는 결합조직의 이상으로 뼈가 잘 부러지는 특징을 가지고 있으며, 질환의 95% 이상은 COL1A1 또는 COL1A2 유전자의 이상으로 발병한다고 알려져 있다. 본 논문에서는 골형성부전증 환자 2 가계를 대상으로 5 주기의 착상전 유전진단을 시행하여 임신에 성공한 사례에 대해 보고하고자 한다. 연구방법: 착상전 유전진단 수행 전에 환자의 단일 림프구에서 증폭성공률과 allele drop-out (ADO) rate을 확인하기 위하여 임상전 검사를 수행하였다. 각각 원인 돌연변이로 확인된 COL1A1 유전자 c.2452G>A와 c.3226G>A를 가지고 있는 골형성부전증 2 가계를 대상으로 5 주기의 착상전 유전진단을 시행하였다. 생검한 할구로부터 원인 돌연변이를 진단하기 위하여 nested PCR 후 HaeIII 제한효소를 이용한 restriction fragment length polymorphism (RFLP) 분석방법과 direct sequencing 방법을 이용하여 진단을 실시하였다. 결 과: Genomic DNA를 이용하여 COL1A1 유전자 검사를 해 본 결과 각 가계의 원인 돌연변이는 c.2452G>A와 c.3226G>A임을 재확인하였으며, 단일세포를 이용한 임상전 검사 결과 첫 번째 사례의 경우 94.2%의 증폭성공률과 22.5%의 ADO rate을 나타내었고, 두 번째 사례의 경우 98.1%의 증폭성공률과 1.9%의 ADO rate를 나타내었다. 착상전 유전진단 결과 첫 번째 사례의 경우, 3 주기의 착상전 유전진단에서 총 34개의 배아 중 31개의 배아에서 진단에 성공하여 91.2% (31/34)의 진단성공률을 나타내었고, 총 19개의 정상 배아 중 8개의 배아 (2.7개/배아이식)를 이식하였다. 세 번째 주기에서 임신에 성공하였고 제왕절개로 건강한 아이를 분만하였다. 두 번째 사례의 경우 2 주기의 착상전 유전진단을 시행하였으며, 총 19개의 배아 모두 진단에 성공하여 100.0% (19/19)의 진단성공률을 나타내었고, 총 11개의 정상 배아 중 4개 (2개/배아이식)의 배아를 이식하였다. 두 번째 착상전 유전진단에서 임신에 성공하였고, 건강한 아이를 분만하였다. 결 론: 착상전 유전진단을 통한 골형성부전증 환자 2 가계에서의 성공적인 임신과 출산은 국내에서 처음으로 보고되는 임상 결과로, 본원의 착상전 유전진단방법은 효과적이고 확실한 방법으로써 앞으로도 더 많은 단일 유전자 이상의 유전질환을 가진 환자들에게 적용하게 될 것이며, 이는 이와 유사한 유전질환을 가지고 있거나 유전질환의 이환 가능성이 있는 부부들에게 정상아의 임신과 출산의 기회를 더욱 많이 제공할 수 있을 것이다. Objectives: Preimplantation genetic diagnosis (PGD) has become an assisted reproductive technique for couples carrying genetic conditions that may affect their offspring. Osteogenesis imperfecta (OI) is an autosomal dominant disorder of connective tissue characterized by bone fragility and low bone mass. At least 95% of cases are caused by dominant mutations in the COL1A1 or COL1A2. In this study, we report on our experience clinical outcomes with 5 PGD cycles for OI in two couples. Methods: Before clinical PGD, we assessed the amplification rate and allele drop-out (ADO) rate of alkaline lysis and nested PCR protocol using heterozygous patient's single lymphocytes in the pre-clinical diagnostic tests for OI. We performed 5 cycles of PGD for OI by nested PCR for the causative mutation loci, COL1A1 c.2452G>A and c.3226G>A, in case 1 and case 2, respectively. The PCR products were analyzed by agarose gel electrophoresis, restriction fragment length polymorphism (RFLP) analysis with HaeIII restriction enzyme in the case 1 and direct DNA sequencing. Results: We confirmed the causative mutation loci, COL1A1 c.2452G>A in case 1 and c.3226G>A in case 2. In the pre-clinical tests, the amplification rate was 94.2% and ADO rate was 22.5% in case 1, while 98.1% and 1.9% in case 2, respectively. In case 1, a total of 34 embryos were analyzed and 31 embryos (91.2%) were successfully diagnosed in 3 PGD cycles. Eight out of 19 embryos diagnosed as unaffected embryos were transferred in all 3 cycles, and in the third cycle, pregnancy was achieved and a healthy baby was delivered without any complications in July, 2005. In case 2, all 19 embryos (100.0%) were successfully diagnosed and 4 out of 11 unaffected embryos were transferred in 2 cycles. Pregnancy was achieved in the second cycle and the healthy baby was delivered in March, 2008. The causative locus was confirmed as a normal by amniocentesis and postnatal diagnosis. Conclusions: To our knowledge, these two cases are the first successful PGD for OI in Korea. Our experience provides a further demonstration that PGD is a reliable and effective clinical techniques and a useful option for many couples with a high risk of transmitting a genetic disease.

역사 속, 우리의 문화와 함게 한 닭 이야기

김민지,Kim, Min-Ji 한국계육협회 2010 월간 닭고기 Vol.16 No.10