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      • KCI등재후보

        유방암 환자의 cyclophosphamide, doxorubicin 유발 부작용에 대한 약침을 포함한 통합 암 치료 1례

        김민서,정유진,홍상훈,Kim, Minserh,Jung, Yu-jin,Hong, Sang-hoon 대한암한의학회 2018 大韓癌韓醫學會誌 Vol.23 No.1

        Objectives: To observe the mitigating effects of a Traditional Korean Medicine(TKM) treatment program especially including pharmacopuncture, with Cyclophosphamide and doxorubicin chemotherapy on a both sides breast cancer patient. Methods: AA 74 year-old female patient diagnosed with both sides breast cancer (Right) pT1bpN0M0, (Left) pT1cpN1Mx was admitted to hospital of Dong-eui university in May of 2017. She received Cyclophosphamide and Doxorubicin from May $31^{st}$ to August $2^{nd}$, 2017 followed by TKM treatment consisting of herbal medicine, acupuncture, moxibustion and pharmacopuncture (Trionycis Carapax, Non-toxic Bee Venom, and Cultivated Wild Ginseng Extract) for a period of almost 4 months, from May $13^{th}$ to August $19^{th}$, 2017. Symptoms were evaluated by the grade of chief complaints refer to Common Terminology Criteria for Adverse Events (CTCAE) and Eastern Cooperative Oncology Group (ECOG). Results: TKM including pharmacopuncture alleviated chemotherapy-induced nausea, fatigue, joint pain, diarrhea, insomnia. Conclusions: This case study potentiates TKM with pharmacopuncture's significant efficacy in aiding breast cancer patients suffering from Cyclophosphamide plus Doxorubicin induced adverse effects. Further research should take place for clear understanding of the exact amount of dosage and safety. Moreover it must be accompanied by long-term follow up researches.

      • KCI등재

        컴퓨터 게임 전후 각막 및 안구의 고위수차 변화

        김민서,황영훈,송종석,Min Seo Kim,Young Hoon Hwang,MD,Jong Suk Song,MD,PhD 대한안과학회 2012 대한안과학회지 Vol.53 No.11

        Purpose: To evaluate changes in corneal and ocular high-order aberration, ocular fatigue, and tear break-up time (TBUT) before and after playing computer games and the correlations among the variables. Methods: Thirty-nine normal healthy subjects played computer games for 1 hour. Ocular fatigue was evaluated with a questionnaire, TBUT was measured with slit-lamp biomicroscopy, and high-order aberrations were measured with a KR-1W aberrometer (Topcon Medical System, Inc., Tokyo, Japan) in each subject before and after playing computer games. The right eye was used for statistical analyses. Results: Subjective ocular fatigue (expressed as the interview score) increased from 4.23 ± 5.35 to 12.05 ± 8.68 after playing games (p < 0.001) and TBUT decreased from 8.03 ± 6.43 sec to 4.90 ± 3.31 sec (p < 0.001). Ocular high-order aberrations in the 4 mm and 6 mm zones were not significantly changed before and after playing games (p = 0.150, p = 0.202, respectively). However, corneal high-order aberrations in the 4 mm and 6 mm zones were significantly increased after playing computer games (p = 0.002, p = 0.002, respectively). Changes in TBUT, interview score, and corneal high-order aberration were not correlated with each other. Conclusions: Playing computer games increased corneal high-order aberrations as well as subjective ocular fatigue and TBUT.

      • KCI등재

        심화상염(心火上炎)으로 진단된 설통(舌痛)과 구강안면부 진전(振顫)의 세심약침을 이용한 한의치료 1례

        김민서,이준수,박상은,홍상훈,Kim, Min-serh,Lee, Jun-su,Park, Sang-eun,Hong, Sang-hoon 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.5

        Objectives: This clinical report describes one patient with the clinical characteristics of burning mouth syndrome accompanied by oro-facial dyskinesia. Methods: The patient with burning mouth syndrome and jaw tremor was treated using the following Korean medicine treatments: the herbal medicines Yukgunja-tang-gami (六君子湯加味) and Sibak-tang-gami (柴朴湯加味) and acupuncture for 16 days, together with 10 Se-sim (Uncaria Ramulus et Uncus) pharmacopuncture procedures. Patient symptoms were evaluated daily using a Visual Analog Scale questionnaire and twice using the STAI (State-Trait Anxiety Inventory) questionnaire. Results: After the treatments, the oro-facial dyskinesia and burning sensation on the tongue were improved by 62.5%. The mental state of anxiety, regarded as the reason for these complaints, was also improved, based on the State-Trait Anxiety Inventory results (67/61 versus 57/52). We found that the improvement was better when combining Se-sim (Uncaria Ramulus et Uncus) pharmacopuncture with the conventional herbal medicine and acupuncture used in Korean medicine. Conclusion: Korean medicine treatments may be valuable for patients with burning mouth syndrome and oro-facial dyskinesia.

      • KCI등재

        항암화학요법 유발 백혈구감소증에 대한 한약치료의 효과 : 체계적 고찰 및 메타분석(2007-2017)

        김민서,정유진,홍상훈,Kim, Min-serh,Jung, Yu-jin,Hong, Sang-hoon 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.4

        Objectives: We performed a systematic review and meta-analysis to explore the recent clinical research trends regarding the effects of traditional herbal medicine (THM) on chemotherapy-induced leukopenia. Methods: Randomized controlled trials that verified effects of herbal medicine treating chemotherapy induced leukopenia were included in the study. A literature search was performed in the English, Chinese, and Korean databases for papers published from January 1, 2007, to September 1, 2017. The selected literature was assessed by Cochrane's Risk of Bias (RoB). Results: Forty-two of 232 randomized controlled trials met the inclusion criteria. The most commonly used herbal prescriptions called '升白湯 (shengbai decoction)' which means elevating the numbers of White blood cells (WBCs). And the mostly included herbs such as Astragali Radix, Angelicae Gigantis Radix, Atractylodis Rhizoma Alba, Codonopsis Pilosulae, Glycyrrhizae Radix, Ligustri Lucidi Fructus are commonly used to elevate qi, blood and yin. The count of WBC in peripheral blood, the level of leukopenia presented in WHO (World Health Organization), and clinical symptoms were used to evaluate the treatments. The effective rate was 68.6-98.18% and the effectiveness was significantly higher in the intervention group than in the control group in 38 articles (p<0.05). No serious adverse events were reported. Only five articles (5/42, 11.9%) were rated as having adequate methodological quality with a low level of bias. Conclusion: Some traditional herbal medicines may be effective as therapeutic treatments for chemotherapy-induced leukopenia, but the majority of reviewed studies were of poor quality. The present findings need to be confirmed by rigorously conducted high-quality trials, including pharmacokinetic studies, to confirm the absence of interactions between traditional herbal medicine agents and chemotherapy.

      • KCI등재

        대상포진 척수염으로 유발된 척수손상 환자의 한방치료 1례

        김민서,심원석,박상은,홍상훈,Kim, Min-serh,Shim, Won-suk,Park, Sang-eun,Hong, Sang-hoon 대한한방내과학회 2016 大韓韓方內科學會誌 Vol.37 No.3

        Objectives: This is a clinical report of one patient with both lower limb paraparesis and numbness as well as sensory impairment caused by a T10 spinal cord injury due to varicella zoster myelitis.Methods: The patient with the spinal cord injury induced by varicella zoster myelitis was treated using Korean medical treatments such as herbal medicine (Palmijihwang-tanggami), acupuncture, and moxibustion.Results: After treatments, improvements in muscular strength and the sensory impairment of both lower limbs were observed as well as improvements in various side effects such as the debridement state and laboratory findings of urine analysis.Conclusion: Given these results, it is considered that Korean medical treatment is effective for patients with spinal cord injury due to varicella zoster myelitis.

      • KCI등재

        일개 농촌지역 다문화가정의 이유식에 대한 지식, 태도 및 실천

        김민서(Min-Seo, Kim),김건엽(Keon-Yeop Kim),김경나(Kyeong-Na Kim),김광환(Kwang-Hwan Kim) 한국산학기술학회 2017 한국산학기술학회논문지 Vol.18 No.7

        본 연구는 농촌지역 다문화가정의 이유식 실태와 지식, 태도 등을 살펴보고자 2015년 12월부터 2016년 3월까지 설문조사로 진행되었으며 92명을 최종 대상으로 하였다. 조사내용으로는 가구 및 아기에 대한 일반적인 특성, 이유식 실태, 이유식에 대한 지식, 태도, 실천 등이었다. 이유식 지식 평균점수는 3.79였고, 태도 평균점수는 4.07이었으며, 실천군은 25.0%였다. 이유식 지식에서는 총 자녀수가 2명 이상, 아기 어머니의 학력이 높은 경우, 출신국적이 중국 또는 일본, 한국어 능력이 상급, 아기 아버지의 학력이 높은 경우, 결혼생활 기간이 6년 이상, 아기 할머니와 동거하지 않는 경우, 이유식 주담당자가 아기 어머니인 경우, 이유식 상담 및 교육을 받은 경우에서 높았다(p<0.05). 이유식 태도에서는 총 자녀수가 2명 이상, 아기 어머니 한국어 능력이 상급, 이유식 주담당자가 아기 어머니인 경우와 이유식 상담 및 교육을 받은 경우에서 높았다(p<0.05). 이유식 실천에서는 아기 어머니 출신국적이 일본과 캄보디아인 경우, 직업이 없는 경우, 이유식 주담당자가 아기 어머니인 경우에서 높았다(p<0.05). 이유식 실천에 따른 지식과 태도 점수를 보면, 이유식 실천군에서 지식(p<0.001) 및 태도가 미실천군보다 높았다. 다문화가정의 영유아 이유식 실천을 위해서 우선 이유식 주담당자인 아기 어머니를 대상으로 한국어 능력을 향상시키는 것이 중요하며, 주변 동료 지지자를 활용해서 이유식과 관련된 올바른 정보를 제공하는 것이 요구된다. 또한 다문화가정의 문화를 이해하면서 출신국적에 따른 차별화된 맞춤형 교육 및 서비스 제공이 필요하다. Abstracts This study was conducted from December 2015 toMarch 2016 to investigate the knowledge, attitude, and practice of baby foods in rural multi-cultural families. The survey included the general characteristics of households and infants, knowledge, attitude, and practice of baby food. The results indicated that the mean score of baby food knowledge was 3.79, 4.07 for attitudes, and the practice group was 25.0%. In the knowledge of baby food, the groups with a total number of two or morechildren, high educational background for both the father and mother, Chinese or Japanese nationality, high Korean language ability, and marriage for at least 6 or more years was higher (p<0.05). In the attitude of baby food, the groups with a total number of two or more children, a higher mother"s Korean language, and the mother in charge of the baby food were higher (p<0.05). In the case of baby food practice, the groups the baby mother was from Japan and Cambodia, there was no occupation, and the mother was in charge of the baby food were higher (p<0.05). Knowledge and attitude according to the practice of baby food showed a higher knowledge (p <0.001) and attitude in the weaning practiced group than unpracticed. To producebaby food for infants in multi-cultural families, it is important to improve the Korean language ability of infant mothers who are in charge of baby food, and it is necessary to provide correct information related to infant formula utilizing the supporters of the neighboring mothers. In addition, it is necessary to provide customized education and support that is contingent upon the nationality of the native people while remaining mindful of the culturalimplications of multi-cultural families.

      • Floral design을 중심으로 한 지속가능한 디자인의 색채분석

        김민서(Minseo Kim),김정음(JeongEum Kim),김유선(Yoosun Kim) 한국색채학회 2018 한국색채학회 학술대회 Vol.2018 No.5

        환경문제가 대두되고 있는 현재, 지속가능한 디자인에 관한 연구가 계속해져왔다. 지속가능한 디자인 여러 분야에서 활용되고 있다. 본 연구는 그 동안 자료가 미비했던 색채의 시각적 효과가 큰 floral design에 초점을 맞추었다. 각 종 설문과 연관검색을 통해, 지속가능한 디자인의 개념에 대해 알아보았다. 다양한 화훼디자인 잡지를 통해 국 · 내외 floral design을 중심으로 한 지속가능한 디자인의 색채, 형태 분석을 하였다. 분석을 통해 향후 floral design을 중심으로 한 지속가능한 디자인을 제안하고자 하였다. 내의 floral design에서 지속가능한 디자인을 주제로 한 작품들의 색상은 주조색과 보조색이 Green계열과 Br계열이 많은 부분을 차지하였는데 이는 식물의 기본이 되는 가지와 잎 소재를 사용하므로써 생태적이고 자연적인 모습을 나타내고자하는 의도를 볼 수 있었고 강조색은 그와 대비되는 색상이나 명도차가 큰 하양이 많은 들어난 색상을 사용하는 것을 볼 수 있었다. 국외도 유사한 경향을 보였으며 국내보다는 좀 더 간결한 색상을 사용하였다. 색조는 국내는 좀 더 채도가 높았고 국외는 채도가 낮은 색조를 많이 사용하였다. 선과 형태의 지속가능한 디자인은 국내와 국되모구 곡선과 원형이 주를 이루었고 직선을 사용하더라도 직선을 연결하여 원형이나 곡선형태로 만들어 사용하였다. 국내는 형태가 좀 더 다양하였고 국외는 형태가 좀 더 단순하였다. 본 연구는 floral design에서의 활용이 미비했던 지속가능한 디자인을 floral design과 연관시켜 그 색채와 형태를 분석하여 앞으로 floral design 분야에서도 지속가능한 디자인에 대한 보다 더 많은 조형작업과 연구가 진행될 것이라 기대한다. 또한 floral design에 보다 더 다양하게 지속가능한 디자인의 색채를 활용할 수 있는 사례가 되기를 기대한다.

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