가와사키 병에 동반된 전방 포도막염의 임상 양상–안과 의사의 역할

김미리내(Mirinae Kim),김선영(Sun Young Kim) 대한안과학회 2016 대한안과학회지 Vol.57 No.2

목적: 가와사키 병 환아에서 흔히 동반되는 전방 포도막염의 유병률 및 안과적 검사 소견을 알아보고, 전형적 가와사키 병 및 비정형가와사키 병에서의 임상 양상을 비교해 보고자 하였다. 대상과 방법: 2013년 10월부터 2015년 1월까지 가톨릭대학교 의정부성모병원 소아청소년과에서 가와사키 병이 의심되어 안과로 진료의뢰된 환아 60명을 대상으로 하여 의무기록을 후향적으로 분석하였다. 결과: 대상 환아 60명 중 46명이 가와사키 병으로 진단되었으며, 이 중 전형적 가와사키 병은 32명, 비정형 가와사키 병은 14명이었다. 가와사키 병으로 진단된 46명 중 32명(69.57%)에서 전방 포도막염이 관찰되었으며, 전형적 가와사키 병 및 비정형 가와사키 병그룹에서의 전방 포도막염 유병률에 통계적으로 유의한 차이는 없었다. 전방 포도막염이 있는 경우 평균 염증세포의 정도는 Standardization of Uveitis Nomenclature (SUN) 1.3이었으며, 전방 포도막염의 평균 지속일은 9.4일이었다. 결론: 가와사키 병은 각막, 전방, 포도막, 시신경 등에 염증반응을 일으킬 수 있는 질환이다. 본 연구에서 임상적으로 가와사키 병이의심되는 환아를 대상으로 하였을 때 전방 포도막염이 가와사키 병을 진단하는 양성예측도는 100%였으며, 민감도는 69.6%, 특이도는 100%였다. 가와사키 병으로 진단된 환아나, 전형적인 진단 기준을 만족하지 못하지만 가와사키 병이 의심되는 환아에서 안과적 검진을 통해 진단, 조기 치료 및 관상동맥 합병증 발생 예방에 도움을 줄 수 있다. Purpose: To identify ophthalmologic features of Kawasaki disease (KD), and to evaluate anterior uveitis incidence in typical KD and atypical KD. Methods: We conducted a retrospective chart review of 60 patients who clinically suspected KD at The Catholic University of Korea Uijeongbu St. Mary’s Hospital between October 2013 and January 2015. Results: Among a total of 60 patients, 46 were diagnosed with KD; 32 (69.57%) were typical KD and, 14 (30.43%) atypical KD. Anterior uveitis was reported in 69.57% of children with KD. Slit-lamp examination showed anterior chamber cells (average Standardization of Uveitis Nomenclature [SUN] grade 1.3) and the anterior uveitis fully resolved within 9.4 days after the onset of the disease. There was no significant difference in typical KD and atypical KD in terms of age, gender, or uveitis incidence. Conclusions: KD may progress with severe cardiac complications, eventually resulting in permanent sequale. Therefore, early diagnosis and therapeutic intervention is important in KD patients. Anterior uveitis as diagnostic criteria for KD has yielded 100% positive predictive value, 69.6% sensitivity and 100% specificity. Ophthalmologic examination may be useful for suspected KD patients, and a high index of suspicion is necessary in patients with anterior uveitis.

만성 골수성 백혈병과 연관하여 발생한 양안의 중심망막정맥폐쇄 1예

김미리내(Mirinae Kim),신정아(Jeong Ah Shin),박영훈(Young Hoon Park) 대한검안학회 2016 Annals of optometry and contact lens Vol.15 No.1

Purpose: To report a rare case of a simultaneous bilateral central retinal vein occlusion, as the initial presentation of chronic myeloid leukemia. Case summary: A 22-year-old man presented with conjunctival injection of both eye, decreased visual acuity of left eye, nausea and dizziness. Ophthalmic examination was consistent with non-ischemic central retinal vein occlusion of both eye. After a systemic evaluation including laboratory examinations, bone marrow biopsy, and abdomen computed tomography, he was diagnosed as chronic myeloid leukemia. The patient received massive hydration and chemotherapy with hydroxyurea, allopurinol, and torsemide. On follow-up at 2 months, his visual acuity recovered to 0.8 in right eye, and 0.63 in left eye. The ocular status has remained stable at 2 year of follow-up. Conclusions: All ocular structures have been found to be involved in patients with leukemia, but visual impairment as the initial symptom of leukemia is rare. A prompt search for the underlying systemic disease should be performed in young patients presenting with central retinal vein occlusion.

블루카본 구축을 위한 위성영상 활용 방안

김미리내(MIRINAE KIM),송태윤(Taeyoon Song) 한국해양환경·에너지학회 2021 한국해양환경·에너지학회 학술대회논문집 Vol.2021 No.5

최근 연안역의 탄소 흡수원(블루카본)으로써 갯벌의 역할이 주목을 받으면서 위성영상을 이용한 갯벌과 서식 식생의 분포를 추정하는 연구가 활발하다. 특히 블루카본 인벤토리 산정을 위해서는 이들 분포 면적에 대한 장기자료가 필수적이다. 본 연구에서는 Landsat TM/ETM+/OLI 영상을 이용하여 30m 공간 해상도를 갖는 갯벌 및 식생 분포를 산출하고자 하였다. 대용량 위성영상 처리 플랫폼인 Google Earth Engine(GEE)에서 Landsat 시계열 영상을 검색하여 분석하였다. 위성영상에서 갯벌과 식생 추출은 식생지수 및 수분지수를 이용한 빈도수 기반의 알고리즘을 개발하여 적용하였다. 산출된 갯벌 및 식생 분포는 현장조사와 고해상도 Google Earth 영상을 이용한 오차행렬(confusion matrix)을 통해 정확도를 평가하였다. 장기 갯벌 및 식생 분포는 동일 기간의 기존 자료와 비교하였으며 시공간 변화를 통한 장기 변동 양상을 살펴보았다. 본 결과는 향후 우리나라 블루카본 인벤토리 구축을 위한 기초자료로 활용될 것으로 기대된다. Recently, tidal flats have received attention as the carbon sink(blue carbon) in the coast and there is a lot of research on the estimation of the spatial distribution for tidal flat and vegetation using satellite imageries. In particular, long term data for distribution is necessary to calculate blue carbon inventory. In this study, we mapped 30m spatial tidal flat and vegetation from Landsat TM/ETM+/OLI. We integrated all the available time-series Landsat imageries in Google Earth Engine(GEE) cloud computing platform for large satellite imageries. We developed a simple frequency based mapping algorithm using vegetation/water indices and apply this method to generate maps of tidal flat and vegetation. The resultant maps were assessed by using a confusion matrix with ground reference data from field surveys and very high spatial resolution images in Google Earth. We compared the resultant maps with other available products and previous studies and analyze spatial-temporal changes of tidal flats and vegetation. This results are expected to use as the basis for blue carbon inventory.

장기 Landsat 위성영상을 이용한 서해안 갯벌 및 식생 분포 변화 조사

김미리내(Mirinae Kim),송태윤(Taeyoon Song) 한국해양환경·에너지학회 2020 한국해양환경·에너지학회 학술대회논문집 Vol.2020 No.7

블루카본 인벤토리 구축을 위한 위성영상 활용 방안

김미리내(Mirinae Kim),송태윤(Taeyoon Song) 한국해양환경·에너지학회 2019 한국해양환경·에너지학회 학술대회논문집 Vol.2019 No.5

단순언어장애아동의 전제의미 추론

김미리내(Mirinae Kim),황민아(Mina Hwang),임종아(JongAh Lim) 한국언어치료학회 2012 言語治療硏究 Vol.21 No.1

Presupposition refers to shared background knowledge which the speaker and listener assume to be true. This study investigated drawing inferences from presuppositional meanings of sentences in children with Specific Language Impairment (SLI) relative to their age-matched (CA) peers and younger language -matched (LA) children. Fourteen children with SLI and 28 typically-developing children participated in this study. All 42 children were first to third graders in elementary schools. For the presuppositional meaning judgment task, the childrenlistened to lists of sentences pairs. The first sentence included presuppositional meaning and the second sentence included true or false meaning to the first sentence. Then, the children were asked to judge wether the meaning of the second sentence is true or false. Half of the 32 questions consisted of explicit presuppositional sentences and the rest were implicit presuppositional sentences. A two-way ANOVA of group (3) x type (2) revealed significant main effects of group and type. The total number of correct responses was significantly lower in children with SLI relative to their peers, but similar to younger language-matched children. However, SLI children exhibited no significant difference in the performance of presupposition types, unlike that of typically developing children. The children with SLI appeared to experience difficulty in inferencing presuppositional meaning and taking advantage of given information.

전대저수지의 녹조원인 생물과 녹조발생 특성

김미리내 ( Mirinae Kim ),송영희 ( Young Hee Song ),이의행 ( Eui Haeng Lee ),남귀숙 ( Gui Sook Nam ) 한국물환경학회 ( 구 한국수질보전학회 ) 2012 한국물환경학회·대한상하수도학회 공동 춘계학술발표회 Vol.2012 No.-

특발성 망막전막에서 유리체절제술 후 테논낭하 트리암시놀론 주사의 효과

김주영(Joo Young Kim),김미리내(Mirinae Kim),박영훈(Young Hoon Park) 대한검안학회 2019 Annals of optometry and contact lens Vol.18 No.1

Purpose: To evaluate the effects of subtenon triamcinolone injections in patients with macular edema or low visual improvement after undergoing vitrectomy for treatment of idiopathic epiretinal membrane. Methods: We conducted a retrospective chart review of 45 eyes of 45 patients who were diagnosed with idiopathic epiretinal membrane and underwent vitrectomy, but did not have more than 0.1 logarithm of the minimum angle of resolution (logMAR) increase in best corrected visual acuity (BCVA) after the operation. Of the 45 patients, 24 patients received 40 mg triamcinolone injection in subtenon space in 2 to 5 months after the operation, and 21 patients received no injection. We analyzed BCVA, central macular thickness (CMT), intraocular pressure (IOP), and complications in 1, 2, 6, and 12 months after the operation. Results: Before the operation, the mean BCVA and CMT in the injection group were 0.53 ± 0.16 and 616.58 ± 143.44 μm, and those in the non-injection group were 0.51 ± 0.25 and 566.29 ± 116.33 μm, respectively. 12 months after the operation, the mean BCVA and CMT in the injection group improved to 0.24 ± 0.17 and 373.11 ± 80.91 μm and those in the non-injection group were 0.28 ± 0.26 and 354.75 ± 80.03 μm, respectively. The difference between the two groups was not statistically significant. At 6 months postoperatively, the IOP was significantly higher in the injection group than that in the non-injection group. Conclusions: Patients with idiopathic epiretinal membrane did not show further improvement in BCVA and CMT when they received the subtenon triamcinolone injection after vitrectomy.

전이성 신장세포암 조기 진단을 위한 액체 생검 기술의 최신 동향

서정윤(Jeong Yoon Suh),맹세정(Se Jung Maeng),김미리내(Mirinae Kim),강수정(Su Jeong Kang),최영욱(Young Wook Choi),장인호(In Ho Chang) 대한비뇨기종양학회 2022 대한비뇨기종양학회지 Vol.20 No.4

미용치료용 엔디-야그레이저에 의한 황반병증에서 항혈관내피성장인자항체로 치료한 1예

마건정(Gun-Jung Ma),박선경(Sun-Kyoung Park),김미리내(Mirinae Kim),박영근(Young-Geun Park),박영훈(Young-Hoon Park),김래영(Rae-Young Kim) 대한검안학회 2021 Annals of optometry and contact lens Vol.20 No.3

목적: 미용치료용 고출력 Nd:YAG 레이저에 우연히 노출된 이후 발생한 황반병증 환자에서 조기 유리체강내 항혈관내피성장인자항체 치료를 보고하고자 한다. 증례요약: 36세의 여자 환자가 내원 일주일 전 미용치료용 고출력 Nd:YAG 레이저에 노출된 이후 발생한 우안의 시력저하를 주소로 내원하였다. 환자의 우안 최대교정시력은 0.1이었고 안저검사에서는 우안 중심와 망막하출혈 소견이 관찰되었다. 빛간섭단층촬영에서 우안 중심와 망막하출혈로 인한 장액망막박리 및 망막색소상피-브루크막 복합체 파열 소견을 관찰할 수 있었다. 이에 대해 총 세번에 걸쳐 유리체강내 베바시주맙(Avastin??, 1.25 mg/0.05 mL; Roche Korea, Seoul, Korea) 주사술을 시행하였다. 6개월 후 시력은 초기 내원 시와 변화가 없었으나, 빛간섭단층촬영에서 우안 중심와 망막하출혈 흡수 소견이 확인되었고 이차성 맥락막신생혈관의 발생이나 맥락막출혈의 재발 소견은 보이지 않았다. 결론: 고출력 미용레이저에 의한 황반하출혈 및 맥락막파열 환자에서 조기의 항혈관내피성장인자항체를 이용한 치료를 환자의 형태학적 호전 및 이차성 맥락막신생혈관 방지에 효과적인 치료 방법으로 고려해볼 수 있다. Purpose: To report a follow up of early intravitreal anti-vascular endothelial growth factor (VEGF) antibody treatment in a patient with maculopathy after accidental exposure to a high-powered cosmetic Nd:YAG laser. Case summary: A 36-year-old female patient visited our clinic with decreased visual acuity in the right eye after accidental exposure to a high-powered cosmetic Nd:YAG laser. The best-corrected visual acuity of the right eye was 0.1 and subretinal hemorrhage on the foveal area was observed during fundus examination. Optical coherence tomography revealed serous retinal detachment with hyperreflective disruption of the ellipsoid zone and retinal pigment epithelium-Bruch’s membrane complex. Intravitreal bevacizumab (Avastin??, 1.25 mg/0.05 mL; Roche Korea, Seoul, Korea) injections were performed three times. Visual acuity was unchanged at 6 months after the first visit. However, complete resolution of the subretinal hemorrhage was observed and there were no signs of secondary choroidal neovascularization or recurrence of choroidal hemorrhage. Conclusions: Early anti-VEGF antibody treatment in a patient with subfoveal hemorrhage and choroidal rupture after high-powered cosmetic Nd:YAG laser exposure improved morphology and prevented secondary choroidal neovascularization.