슬러지 폐기물을 활용한 반도체급 균일한 콜로이달 실리카 나노입자의 제조 및 CMP 응용

김동현,김지원,제갈석,김민정,김하영,김민상,김상춘,박선영,윤창민,Kim, Dong Hyun,Kim, Jiwon,Jekal, Suk,Kim, Min Jeong,Kim, Ha-Yeong,Kim, Min Sang,Kim, Sang-Chun,Park, Seon-Young,Yoon, Chang-Min 유기성자원학회 2022 유기물자원화 Vol.30 No.3

This study suggests the effective recycling method of sludge waste from various industrial fields to synthesize uniform colloidal silica nanoparticles. In detail, polymers are removed from the sludge waste to attain sludge-extracted silica (s-SiO₂) micron-sized particles, and ammonia assisted sonication is applied to s-SiO₂, which has effectively extracted the silanol precursor. The nano-sized silica (n-SiO₂) particles are successfully synthesized by a typical sol-gel method using silanol precursor. Also, the yield amounts of n-SiO₂ are determined by the function of s-SiO₂ etching time. Finally, n-SiO₂-based slurry is synthesized for the practical CMP application. As a result, rough-surfaced semiconductor chip is successfully polished by the n-SiO₂-based slurry to exhibit the mirror-like clean surface. In this regard, sludge wastes are successfully prepared as valuable semicondutor grade materials.

Complete genome sequence of Comamonas sp. NLF-7-7 isolated from biofilter of wastewater treatment plant

김동현,한국일,권해준,김미경,김영국,최두호,이근철,서민국,김한솔,이정숙,김종국,Kim, Dong-Hyun,Han, Kook-Il,Kwon, Hae Jun,Kim, Mi Gyeong,Kim, Young Guk,Choi, Doo Ho,Lee, Keun Chul,Suh, Min Kuk,Kim, Han Sol,Lee, Jung-Sook,Kim, Jong-Guk The Microbiological Society of Korea 2019 미생물학회지 Vol.55 No.3

Comamonas sp. NLF-7-7 was isolated from biofilter of wastewater treatment plant. The whole-genome sequence of Comamonas sp. NLF-7-7 was analyzed using the PacBio RS II and Illumina HiSeqXten platform. The genome comprises a 3,333,437 bp chromosome with a G + C content of 68.04%, 3,197 total genes, 9 rRNA genes, and 49 tRNA genes. This genome contained pollutants degradation and floc forming genes such as sulfur oxidization pathway (SoxY, SoxZ, SoxA, and SoxB) and floc forming pathway (EpsG, EpsE, EpsF, EpsG, EpsL, and glycosyltransferase), respectively. The Comamonas sp. NLF-7-7 can be used to the purification of wastewater.

김연아 선수의 ``값진 준우승``: 2011세계피겨선수권대회 관련 보도의 서사구조와 이데올로기

김동현 ( Dong Hyun Kim ) 한국스포츠과학원 2012 체육과학연구 Vol.23 No.1

This study looks into the narrative structure of newspaper media on ``precious winning of the second prize`` of Yuna Kim in the World Figure Championships 2011 and analyzes the socio-cultural ideology representation in it. Also, from the way how the media describe the sports celebrity, the study attempted to read the unique cultural pattern of medias to conserve the fame and marketability of sports celebrity, For the analysis, this study selected 82 news articles from 5 different newspapers right before and after the world Figure championships 2011, and derived the conclusion by using narrative analysis method. The narrative structure is divided into four states: ``waiting for return of queen``, ``the figure queen returns``, ``precious winning of the second prize`` and ``retake of crown through figure`` In each state, medias, in accordance with the narration through a reflection of her successful discourse on national identity, through the identification with the nation, through the nationalism sentiment, through her unconditional patriotism, actively gave an effort to maintain the fame and marketability of Yuna Kim. The chief topic of this research, Korean Figure Skater Kim Yuna`s ``precious winning of the second prize``, is resulted from the integration of her unconditional patriotism grounded on nationalism having an inseparable relationship with sports.

기상반응법에 의한 질화티타늄 제조

김동현,김동현,김동현,원창환,Kim, Dong-Hyeon,Kim, Dong-Hyeon,Kim, Dong-Hyeon,Won, Chang-Hwan 한국재료학회 1997 한국재료학회지 Vol.7 No.12

TiN은 기상반응법으로 티타늄판과 질소가스의 질화반응에 의해 제조되었다. $\delta$-TiN은 약 1100-140$0^{\circ}C$의 온도 범위에서만 형성되는데 반해, 110$0^{\circ}C$이하의 온도에서는 $\varepsilon$-TiN 상도 관찰할 수 있었다. $\delta$-TiN의 미소정도값은 3000$\pm$300kg/m$m^2$였고, 격자상수는 0.4226$\mu\textrm{m}$였다. 가스의 유동속도가 0.7$\ell$/min의 속도이하에서는 확산과정에 의해 지배됨을 알 수 있었다. 활성화에너지가 110$0^{\circ}C$이상에서는 67.6Kcal/mol이었고 110$0^{\circ}C$이상에서는 13.9Kcal/mol이었던 것으로 보아 반응메커니즘이 110$0^{\circ}C$를 기점으로 변한다는 것을 명백히 관찰할 수 있었다. 그리고 증착속도가 확산과정에 의해 지배되는 영역에서 TiN의 증착속도는 전체 유량의 제곱근에 비례하였다.

ICT 기반의 인삼 공정 육묘 시 상토에 따른 발아 특성

김동현,김연복,구현정,백현진,이수빈,홍의기,김상기,장광진,Kim, D.H.,Kim, Y.B.,Koo, H.J.,Baek, H.J.,Lee, S.B.,Hong, E.K.,Kim, S.K.,Chang, K.J. 국립한국농수산대학교 교육개발센터 2021 현장농수산연구지 Vol.23 No.2

As a result of examining the germination rate between ginseng varieties, Jagyongjong varieties had the highest germination rate, and Yeonpung. had the lowest germination rate. In the ginseng seed germination rate experiment, the highest germination rate and growth condition were shown in artificial soil conditions of the ratio of Peatmoss 6.5: Pearlite 2: Masato 1.5. Good soil conditions require adequate soil moisture forces during the incubation period. The cultivation of ginseng medicinal crops requires optimal soil breathability, soil pH, and soil stabilization, which are important for root breathing. Microbial activity in the soil has a great influence on the growth of ginseng. The optimum pH of the soil for ginseng cultivation is 5.0-5.5 As a result of the experiment, the soil remained in an appropriate range after a month. In general, when the EC concentration value of the soil for ginseng cultivation is 0.2 mS/cm or more, growth deteriorates, and when the EC concentration value is 0.5 mS/cm or more, concentration obstacles such as root decay occur. As a result of the analysis, the higher the concentration value of EC, the more likely it is to interfere with ginseng growth.

ICT 기반의 인삼 공정 육묘 시 인삼 식물체 분석

김동현,김연복,구현정,백현진,이수빈,홍의기,김상기,장광진,Kim, D.H.,Kim, Y.B.,Koo, H.J.,Baek, H.J.,Lee, S.B.,Hong, E.K.,Kim, S.K.,Chang, K.J. 국립한국농수산대학교 교육개발센터 2021 현장농수산연구지 Vol.23 No.2

In order to compare and investigate the growth rates of each of the various soils, the soil mixing ratios were varied to four soils (Pitmos, Pearlite, Masato, General Soil, and Cocopeat). Ten were selected for each soil ratio and the average length and weight were compared. As a result, in the ratio of No. 1 pitmos 6.5: Perlite 2: Masato 1.5, it was measured as 16.36cm, 0.60g. In the ratio of No. 2 pitmos 10, 13.74cm, 0.41g. In the ratio of No. 3 general clay 10, it was measured as 12.43cm, 0.26g. 4 general clay 8, 0.39g. The growth rate of each soil was measured to be superior to that of other soil growth environments in the ratio of pitmos 6.5: pearlite 2: masato 1.5 soil. For ginseng plant analysis, 30 ginseng plants grown in the average length and weight of each soil at a ratio of 6.5: pearlite 2: masato 1.5 and relatively low-result general soil were selected and analyzed. As a result, 1,040ppm of nitrite nitrogen(NO₃-N) was higher in ginseng plants grown in general soil. There was no significant difference in phosphoric acid(P), potassium(K), and magnesium(Mg). Ginseng is characterized by poor growth when it exceeds 300ppm by combining ammonia tae (NH₄-N) and nitrate tae (NO₃-N) nitrogen. In addition, nitric acid produced in a part of this nitrite makes the pH reaction of the soil acidic, and the nitrite remaining in the soil evaporates into gas.

저강도 레이저가 흰쥐 창상 후 급성통증에 미치는 영향

김동현,백수정,김석범,송주민,김진상,Kim Dong-Hyun,Baek Su-Jeong,Kim Suk-Bum,Song Ju-Min,Kim Jin-Sang 대한물리치료학회 2002 대한물리치료학회지 Vol.14 No.2

This study was performed, using c-fos and Substance P, to investigate the effect of GaAlAs laser on acute pain model induced by wound in lumbar region's spinal level. The test group was divided into control and experimental group. Control group is shamed group(c-fos and substance P expression after non-irradiation by a GaAlAs laser), The experimental group was divided into two subgroups: one is experimental group I (c-fos expression after irradiation by a GaAlAs laser), and the other is experimental group II (substance P expression after irradiation by a GaAlAs laser). The results of this study were as following: 1. The numbers of c-fos immunoreactive neuron in spinal cord was increased markedly 1 day after wound, and decreased gradually from 1 day to 2 days in wound with GaAlAs laser irradiation. 2. The changes of the average percentages of substance P immunoreactive neurons in spinal cord was increased markedly 1 day after wound, and decreased gradually from 1 day to 2 days in wound with GaAlAs laser irradiation. Therefore, decreasing the changes of c-fos and substance P expression after irradiation by a GaAlAs laser indicates and GaAlAs laser have effect on pain control.

GaAIAs 레이저 조사가 흰쥐 창상부위 상피조직의 EGF 발현에 미치는 영향

김동현,백수정,배주한,김석범,권영실,김진상,Kim, Dong-Hyun,Baek, Su-Jeong,Bae, Ju-Han,Kim, Suk-Bum,Kwon, Young-Shil,Kim, Jin-Sang 대한물리치료학회 2001 대한물리치료학회지 Vol.13 No.3

This study was performed. using EGF, to observated the effect of GaAIAs laser on wound model induced designedly in lumbar region. The results of this study were as following: 1. In expression of EGF which used marker of wound healing, laser irradiating group made EGF to more induce significantly than laser non-irradiating group at 3 days. 2. EGF immunoreactivity in epidermis were increased markedly 3 days after wound, and increased gradually from 1 day to 2 days in wound which is laser irradiation. Therefore, EGF immunoreactivity which increased after wound with GaAIAs laser irradiation indicate that GaAIAs laser have wound healing effect. This study also can become a part of scientific evidence on electrotherapy through measuring quantitively effects of GaAIAs laser in wound

Capsaicin 적용 후 손상된 흰쥐 척수내 c-fos와 HSP70의 발현

김동현,김석범,백수정,김진상,Kim, Dong-Hyun,Kim, Souk-Boum,Baek, Su-Jeong,Kim, Jin-Sang The Korean Society of Physical Therapy 2002 대한물리치료학회지 Vol.14 No.1

C-fos는 원종양유전자(proto-oncogene)인 v-fos의 세포 동족체로써, 성장인자나 신경전달 물질에 의해 수분 내에 다양한 형태의 세포에서 활성화된다. Fos단백질은 스트레스와 통증 과정의 신호전달기전에서 세포활동을 조절하는 3차전령으로 활동한다. 열충격 단백질(Heat shock protein : 이하 HSP)은 계통발생학적으로 초기 척추 동물에서부터 발현되며 생체방어체계의 중요한 인자로 세포가 고열, 외상, 허혈 등의 스트레스에 직면했을 때 발현이 증가하는 단백질로 알려져 있다. 본 연구에서는 캡사이신(capsaicin)으로 말초 신경병변을 유발시킨 후 통각신경활성의 지표로 이용되는 원종양 유전자인 c-fos의 발현과 열 또는 스트레스로 야기되는 손상에 대한 조직의 방어작용으로 발현되는 HSP 70의 발현을 동시에 관찰함으로서, 급성으로 유발된 말초 신경병변의 확인과 동시에 실험동물 체내에서 방어적인 역할을 밝히는 일환으로 이 실험을 실시하였다. 본 실험의 결과는 다음과 같다; 1. 척수 등쪽뿔 천층(Laminae I and II)에서 각각 c-fos와 HSP70을 항원으로 하는 면역조직화학적 방법으로 염색한 표본에서 0.9% NaCI 투여 2시간 후 c-fos와 HSP70의 양성을 나타내는 세포는 전혀 없음을 알 수 있었다. 2. 척수 등쪽뿔 천층에서 c-fos 단백질을 항원으로 하는 면역조직화학적 방법으로 염색한 표본에서 Capsaicin 투여 2시간 후 c-fos 단백질에 양성을 나타내는 세포가 많이 발현됨을 육안적 관찰로서 알 수 있었다. 3. 척수 등쪽뿔 천층에서 HSP70을 항원으로 하는 면역조직화확적 방법으로 염색한 표본에서 Capsaicin 투여 2시간 후 HSP7O의 양성을 나타내는 세포가 보통수준으로 발현됨을 육안적 관찰로서 알 수 있었다. 이 실험의 결과로 볼 때, 화학적인 신경병변 유발물질에 의한 손상을 방어하기 위해서 체내에는 내인성 물질이 형성될 것이라는 추측과 c-fos 가 다른 유전자의 발현을 유도한다는 점을 함께 고려 하였을때, Capsaicin에 의한 말초 신경병변에서 c-fos 발현이 많이 나타나는 것은 손상을 방어하는 물질의 생성에 관여하기 때문이며, 방어물질 중 이 실험에서 본 HSP70도 증가한 내인성 방어물질의 하나라고 할 수 있을 것이다.

새로운 계열의 선택적 COX-2 저해제: Luotonin A 동족체 및 그 질소 유도체

김동현,량경록,오준석,장영동,김진철,홍태균,황남경,정환기,김윤경,장현욱,Kim, Dong-Hyeon,Liang, Jing-Liu,Oh, Joon-Seok,Jahng, Yurng-Dong,Kim, Jin-Cheul,Hong, Tae-Gyun,Hwang, Nam-Kyung,Chung, Hwan-Ki,Kim, Yun-Kyung,Chang, Hyeun-Wook 대한약학회 2007 약학회지 Vol.51 No.5

A series of luotonin A homologues and their aza-analogues were prepared and evaluated their inhibitory activities on COX-1 and 2 as well as their selectivities on COX-2. The aza-analogue of dimethylene-bridged homologue of luotonin A, 3,3'-dimethylene-2-(1',8'-naphthyrid-2'-yl)-4(3H)-quinazolinone (2b), exhibited strongest inhibitory activity against COX-1 and COX-2 dependent phase of prostaglandin $D_2$ generation in mouse bone marrow-derived mast cells in a concentration-dependent manner with an $IC_{50}$ of 39.3 and $1.89{\mu}M$, respectively. Selectivity of 2b on COX-2 over COX-1 was 21 which implied 2b can be a potential lead for the development of selective COX-2 inhibitor.