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        • 항산균에 대한 거식세포의 식균작용에 면역조작이 미치는 영향

          김동순 최신의학사 1972 最新醫學 Vol.15 No.12

          Numerous studies on the interactions between tubercle bacilli and macrophages from normal or immunized animals were reported; however, the contributory significance of the rates or quantities of phagocytosis of tubercle bacilli by macrophages to resistance to tuberculosis were incompletely established. It will be worth-while to investigate further comparatively the phagocytic activity of normal or immunized macrophage against tubercle bacilli as one of criteria for degree of resistance to tuberculosis. Thus, an experiment was planned, and performed to study the effect of immunization on the phagocytosis of mycobacterium, by macrophages of normal or immunized rabbits at different temperatures which might influence the metabolic activities of various cells. Normal, or immunized rabbit macrophages by Mycobacterium tuberculosis(H3,Rv) or Mycobacterium bovis (BCG) were collected from peritoneal cavity, suspended in the CMF medium containing normal or immune sera, and mix with the suspensions of mycobacteria. The macrophage-mycobacteria suspensions were maintained for 90 minutes at 37°C and 33°C, and the appearance rates of macrophages with AFB and the percentages of the intacellular units to the total bacteria units were observed. The results of the observation were summerized as follows; 1) The rates of phagocytosis of mycobacteria by macrophages were significantly increased by immunization with H37Rv or BCG strain, while showing the specificity immunologically by some degrees. 2) Higher percentages were showed in the intracellular units to the total bactera units of H37Rv strain than of BCG stirain in both normal and immune sera. 3) The most active phagocytosis was observed from 15 minutes to 60 minutes through incubation period. 4) No significant difference was observed under the designed conditions of experiments between 37°C and 33°C.

        • KCI우수등재
        • SCOPUSKCI등재

          간동정맥루에서 99mTc-macroaggregated albumin 검사의 의의

          김동순,안일민 대한핵의학회 1985 핵의학 분자영상 Vol.19 No.2

          The radioisotop study using 99mTc-macroaggregated Albumin is a simple, non-invasive test for the diagnosis of pulmonary arteriovenous fistula(PAVF). It can show the presence . of the right-to-left shant at the lung level using the dynamic study, and also the shunt fraction can be estimated. Here we presented the results of the radioisotope study on two patients with PAVF. In one patient, the cardiac catheterization was done and calculated shunt fractions by both method were well matched.

        • KCI등재

          Multi-modal oviposition model of overwintered Unaspis yanonensis (Hemiptera: Diaspididae) females and its field validation

          김동순,이준호 한국응용곤충학회 2015 Journal of Asia-Pacific Entomology Vol.18 No.4

          A multi-modal oviposition model of overwintered Unaspis yanonensis (Kuwana) (Hemiptera: Diaspididae) was developed to predict the population of crawlers in citrus orchards for future incorporation into a population model of U. yanonensis. Three temperature-dependent components, namely, temperature-dependent total fecundity (TDF), age-specific cumulative oviposition rate (ACO), and age-specific survival rate (ASR) functions, were incorporated into the oviposition model. Overwintered U. yanonensis females showed cyclic oviposition activity. Thus, we assumed that the oviposition curve of U. yanonensis consisted of three independent oviposition cycles, and therefore estimated both TDF and ACO curves. The ASR curve, however, was not separated into three cycles. The chronological age of U. yanonensis was converted into a normalized age by the summation of pre-oviposition completion rates (1/pre-oviposition time in days). The estimated models of TDF, ACO, and ASR were successfully integrated to construct the multi-modal oviposition model. The model outputs accurately reflected the actual temporal abundances of U. yanonensis crawlers, displaying characteristic bimodality in the field. The peak time predictability of the model was largely robust. The mean discrepancies were no more than 3 days in all cases as indicated by one-tailed one sample t-test. Also, the Chi-square test showed no significant difference between observed and predicted peak dates. Furthermore, the model showed high robustness, as the Pearson’s correlation coefficients between actual observations and model outputs indicated significantly positive values and were mostly high values N0.80. Consequently, the developed oviposition model should be useful for timing control action targeting on the crawler population in citrus orchards.

        • KCI등재
        • KCI등재

          애널리스트의 기업경영 모니터링 역할에 관한 연구

          김동순 한국기업경영학회 2011 기업경영연구 Vol.18 No.3

          This study examines the relationship between earnings management and analyst coverage for the Korean firms, reflecting the issue of financial and accounting information quality raised during the Asian and global financial crises. During the study period from 2003 and 2009, we measured the dependent variable, i.e., earnings management by the size of discretionary accruals, and both the number of analysts following a firm and the number of analyst reports are used as the proxy for analyst coverage. We also include firm-specific control variables such as financial leverage, growth potential and profitability. We hypothesize that analyst coverage will reduce managers' behavior of earnings management. We found the following interesting empirical results. First, discretionary accruals and total accruals are significantly and negatively related to analyst coverage. So, when more analysts follow a firm, the manager's earnings management behavior is reduced. Second, there are more reports published by analysts,the behavior is also reduced. Third, the absolute value of accruals, a proxy for the possibility of earnings management and earnings forecasting accuracy, is negatively related to the corporate governance index, implying that firms with better corporate governance system has less earnings management. Fourth, the changes in analyst coverage have a negative relation with those in accruals,and therefore managers has less incentive to manage earnings when more analyst cover firms over time. Firm-specific factors are also related to earnings management. Debt ratios are positively related to the absolute value of discretionary accruals. So when managers expect a default, they seem to think about earnings management. Firms’ growth potential and profitability also have a positive relation with accruals. However, firm size is negatively associated with accruals, implying that larger firms may have additional monitoring mechanisms. In conclusion, Korean domestic analysts seem to play a vital role of management monitoring in the Korean capital market. Therefore, it is suggested that analysts should develop their expertise and more analysts should follow and monitor firms in order to enhance Korean firms’ governance structure in the future. 본 연구는 외환위기와 글로벌 금융위기 등을 겪으면서 국내외 자본시장에서 주요 이슈가 된 재무 및 회계정보의 질과 관련하여 기업의 이익관리(earnings management)와 애널리스트 역할간의 관계를분석하였다. 2003~2009년 연구기간에 있어 국내기업들의 이익관리를 측정하기 위한 대용변수로서 재량적발생액(discretionary accruals)을 종속변수로, 해당 기업에 대한 분석보고서를 작성한 애널리스트의 수 등을 주요 설명변수로 채택하였다. 최근 들어 국내에서 기업에 대한 주요 정보제공자로서 활동하고 있는 애널리스트들이 모니터링 역할도 하는지를 분석한 바, 특히 경영자의 이익관리 행태에 영향을 미치는지를 중점적으로 분석하였다. 본 연구의 주요 결과는 다음과 같이 요약된다. 첫째, 이익관리의 대용변수로서 재량적발생액과 총발생액 모두 애널리스트 커버리지, 즉 기업을 분석하는 애널리스트의 수와 음(-)의 관계를 나타내서 애널리스트 커버리지가 많은 기업일수록 경영자의 이익관리 행태가 줄어드는 것으로 나타났다. 둘째,애널리스트의 보고서 수 및 애널리스트 1인당 평균 보고서로 측정한 애널리스트 커버리지의 경우에도 이들발생액과 음(-)의 관계를 보여 이익관리 행태를 줄이는 경향이 있었다. 셋째, 발생액의 절대값으로 측정한이익관리의 가능성 내지 이익 예측력은 기업지배구조 지수와 음(-)의 관계를 나타내서 지배구조가 우수한기업일수록 이익관리가 적고 이익의 예측력도 높아지는 것으로 나타났다. 넷째, 이익관리 행태의 변화와 애널리스트 커버리지의 변화 간에는 음(-)의 관계가 나타나서 애널리스트 수, 보고서 수가 증가할수록 경영자는 이에 대해 민감하게 반응하여 이익관리를 줄이는 유인을 가지는 것으로 보인다. 이에 따라 더 많은 애널리스트들이 기업을 분석함으로써 경영자의 자의적인 이익관리 행태를 줄일 수 있는 것으로 실증되었으며,결국 애널리스트는 경영자에 대한 모니터링 역할을 수행하는 것으로 평가된다.

        • KCI등재

          A case of restless legs syndrome in a child presenting with growing pains

          김동순,신홍범,안영민 대한소아청소년과학회 2008 Clinical and Experimental Pediatrics (CEP) Vol.51 No.11

          Restless legs syndrome (RLS) is a common neurological sleep disorder in adults characterized by the following diagnostic criteria: an urge to move that is usually associated with unpleasant sensations and symptoms that are worse at rest, relieved by movement, and most severe at night. The definite diagnosis of RLS in children is stricter and consists of self-description of leg discomfort or the presence of 2 of 3 supportive criteria combined with 4 essential criteria for diagnosis in adults. RLS in childhood has often been misdiagnosed as growing pains or a part of normal development. As a result, physicians have often missed the chance for proper management. We diagnosed a case of RLS in a 5-year-old boy presenting with growing pains, whose mother was found to have had RLS since childhood. We confirmed RLS by using a polysomnograph, in which the indices of periodic limb movement syndrome (PLMS) and periodic limb movement during wakefulness (PLMW) were recorded to be compatible with RLS criteria. The patient‘s ferritin level was low normal, and his symptoms improved after taking iron supplements.

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