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Spontaneous Retroperitoneal Hemorrhage and Hemothorax After Intravenous Heparin Treatment
김도회,이승진,전웅,박상호,이세환,신원용,진동규 대한심장학회 2009 Korean Circulation Journal Vol.39 No.1
Spontaneous retroperitoneal hemorrhage is a rare complication after percutaneous coronary intervention (PCI). The patient can be in danger if bleeding is not stopped immediately. However, it is not easy to control the bleeding completely because the bleeding foci can be multiple and there is a rich network of collateral circulation. We report a case of spontaneous retroperitoneal hemorrhage successfully treated using multiple microcoils. One year later, panhypopituitarism occurred as a likely consequence of the accompanying hypovolemic shock. Spontaneous retroperitoneal hemorrhage is a rare complication after percutaneous coronary intervention (PCI). The patient can be in danger if bleeding is not stopped immediately. However, it is not easy to control the bleeding completely because the bleeding foci can be multiple and there is a rich network of collateral circulation. We report a case of spontaneous retroperitoneal hemorrhage successfully treated using multiple microcoils. One year later, panhypopituitarism occurred as a likely consequence of the accompanying hypovolemic shock.
Driving Simulator에서 Simulator Sickness의 정량적 측정에 관한 연구
김도회,박민용,이근희 한국산업경영시스템학회 1998 한국산업경영시스템학회지 Vol.21 No.48
The purpose of this study is to propose and to apply new Revised Simulator Sickness Questionnaire(RSSQ) that is effective quantification tool by revising and complementing SSQ because Simulator Sickness Questionnaire(SSQ), which is being used generally to quantify Simulator Sickness has several problems. For this study, we reduced 31 symptoms that are related to Simulator Sickness to 22 symptoms and derived weighting for each other from 15 experts. We developed new RSSQ with 22 symptoms and implemented factor analysis by using 142 RSSQ which is questioned before and after getting on simulator. It was classified to four major symptom groups as the result of the factor analysis. They are Disorientation, Oculomotor, Nausea, and Confuse. The scoring system of RSSQ provides subscales score of Disorientation, Oculomotor, Nausea, and Confuse as well as total severity. The scoring system of RSSQ which is proposed by this study is expected to improve accuracy of measure compared with an existing scoring system of SSQ, and to contribute with understanding the effect of Simulator Sickness more adequately and clearly.
자동차 모의운전환경에서 Simulator Sickness의 예측 회귀모형 개발
김도회 한국시뮬레이션학회 1999 한국시뮬레이션학회 논문지 Vol.8 No.4
This study proposed multiple linear regression models to predict those who can be easily infected simulator sickness(SS) in simulator or virtual reality environment. In this study, SSQ(Simulator Sickness Questionnaire) scores which are recently used for assessing SS, and RSSQ(Revised Simulator Sickness Questionnaire) scores are selected as dependent variables. Also ten dependent variables are used. The results are these models coefficient of determination(max $R^2=0.52$) is improved 18% more than Kolasinski's model($R^2=0.35$), and it became easy to predict with simple data. Accordingly, we can easily predict who will be apt to get into simulator sickness.
대황목란탕(大黃牧丹湯)의 배오(配伍)분석과 그 약리활성
김도회,윤미정,신순식,Kim, Do Hoy,Yoon, Michung,Shin, Soon Shik 대한한의학방제학회 2018 大韓韓醫學方劑學會誌 Vol.26 No.1
Objectives : I analysed daehwangmokdan-tang's compatibility principle by the system of chief, deputy, assistant, and envoy and investigated pharmacological activities by categorizing with chemical components, molecular level, cellular level, animal level and human level based on Korean and Chinese studies for this formula. Methods : Daehwangmokdan-tang's compatibiltity principle was examined by the system of chief, deputy, assistant, and envoy. I looked into studies that presented in Korea from 1956 to 2016 about daehwangmokdan-tang through KOREA INSTITUTE OF ORIENTAL MEDICINE, Korean medicine information system (OASIS) and in Chinese for 20 years about daehwangmokdan-tang through China National Knowledge Infrastructure, CNKI. Then classify into chemical components, molecular level, cellular level, animal level and human level to analyse. Results : According to the system of chief, deputy, assistant, and envoy, chief herb is Rhei Radix et Rhizoma and Moutan Cortex, deputy herb is Natrii Sulfas and Persicae Semen, assistant and envoy herbs are Trichosanthis Semen. The amount of extraction of paeonol, total anthraquinone, and conjugated anthraquinone from daehwangmokdan-tang with the formulation of the system of chief, deputy, assistant, and envoy was the highest, and in the formulation of chief herb and deputy herb, the extraction amount of paeonol and conjugated anthraquinone was the lowest. With other formulations, the amount of extraction of total anthraquinone and conjugated anthraquinone was improved, although the degree was different. In particular, when it is blended with Persicae Semen as a deputy herb, the extraction amount of total anthraquinone and conjugated anthraquinone of Rhei Radix et Rhizoma as a chief herb is greatly increased, and the extraction amount of paeonol is rather different, but it is lowered. It was found that the amount of Mg Ca K Na in daehwangmokdan-tang was the highest. Pharmacological activities can be detected in inflammatory mediators and enzymes for molecular level. For cellular level, it can be determined in lipopolysaccharide (LPS)-stimulated RAW 264.7 cell line. In mouse and rats for animal level and human level, in inflammatory diseases (acute appendicitis, acute pancreatitis, acute cholecystitis, acute abdominal disease, ect.), pharmacological activities was caught. Conclusions : From the above results, daehwangmokdan-tang is composed in line with the system of chief, deputy, assistant, and envoy, suggesting that there is certain rationality and scientific. Pharmacological activities of daehwangmokdan-tang are effective to anti-inflammation, improvement of sepsis, analgesic, muscle relaxation, and improvement of intestinal flora and its metabolites. Daehwangmokdan-tang is consistent with the action of diuresis and anti-inflammation in terms of the content of elements, suggesting that there is action of purging fire and removing blood stasis, defecation detoxification, cooling blood and clearing heat and activating blood and dispersing stasis.
김도회,박상성,신영근,장동식 한국경영과학회 2008 한국경영과학회 학술대회논문집 Vol.2008 No.5
Technological convergence is progressed rapidly also technology life cycle is shorten in 21th century. So it"s very important that finding an emerging technology field for R&D. But most of forecasting on emerging technology have been depended on experts, therefore it caused many problem like wasting of time and cost. In this paper, we creat a visualized patent-map including relation of each patent using an patent analysis tool, then estimate and forecast an emerging technology field. And thereby we apply the proposed method to the emerging technology forecasting of NCW information security technology.
김도회,박상성,신영근,장동식 대한산업공학회 2008 대한산업공학회 춘계학술대회논문집 Vol.2008 No.5
Technological convergence is progressed rapidly also technology life cycle is shorten in 21th century. So it"s very important that finding an emerging technology field for R&D. But most of forecasting on emerging technology have been depended on experts, therefore it caused many problem like wasting of time and cost. In this paper, we creat a visualized patent-map including relation of each patent using an patent analysis tool, then estimate and forecast an emerging technology field. And thereby we apply the proposed method to the emerging technology forecasting of NCW information security technology.
김도회,윤미정,신순식 대한한의학방제학회 2018 大韓韓醫學方劑學會誌 Vol.26 No.4
Objectives : We analyzed the principle of compatibility of socheongnyong-tang and expanded the range of application in clinical practice. Methods : Socheongnyong-tang was analyzed by the compatibility principle through the system of chief, deputy, assistant, and envoy, but the basic formulas of 『Discussion of Cold Damage』 and 『Synopsis of the Golden Chamber』 was used. Results : Socheongnyong-tang treats exterior wind-cold and interior water accumulation. Exterior wind-cold is treated mainly by exterior-releasing herbs constituting mahwang-tang and gyeji-tang in 『Discussion of Cold Damage』, and interior water accumulation is treated mainly by retained fluid-resolving herbs constituting yeonggamomigangsinha-tang, yeonggamomigagangsinbanhahaengin-tang and yeonggamomigagangsinbanhaengdaehwang-tang in 『Synopsis of the Golden Chamber』. Depending on the weight of exterior wind-cold and interior water accumulation, the disease condition is classified as a case where exterior wind-cold is heavier than interior water accumulation, a case where exterior wind-cold is lighter than interior water accumulation, and a case where it is equivalent. When exterior wind-cold is heavier than interior water accumulation, chief herbs are Ephedrae Herba and Cinnamomi Ramulus of exterior-releasing herbs series and deputy herbs are Zingiberis Rhizoma and Asari Radix et Rhizoma of retained fluid-resolving herbs series. When exterior wind-cold is equal to the disease condition of interior water accumulation, chief herbs are Ephedrae Herba of exterior-releasing herbs series and Zingiberis Rhizoma of retained fluid-resolving herbs series, and deputy herbs are Cinnamomi Ramulus of the exterior-releasing herbs series and Asari Radix et Rhizoma of retained fluid-resolving herbs series. When exterior wind-cold is lighter than interior water accumulation, chief herbs are Zingiberis Rhizoma and Asari Radix et Rhizoma of retained fluid-resolving herbs series and deputy herbs are Ephedrae Herba and Cinnamomi Ramulus of exterior-releasing herbs series. In any case, assistant herbs are Pinelliae Rhizoma, Paeoniae Radix alba, and Schisandrae Fructus, and envoy herb is Glycyrrhizae Radix preparata. Conclusions : In conclusion, socheongnyong-tang must differently formulate the system of chief, deputy, assistant, and envoy according to the grade of exterior wind-cold and interior water accumulation. These results suggest that socheongnyong-tang can be applied flexibly when applied in clinical practice to enhance the therapeutic effect.
김도회,서부일,김보경,김경철,신순식,Kim Do-Hoy,Seo Bu-il,Kim Bo-Kyung,Kim Gyeong-Cheol,Shin Soon-Shik 대한한의학방제학회 2003 大韓韓醫學方劑學會誌 Vol.11 No.2
The Theory for Monarch, Minister, Adjuvant and Dispatcher (or the Theory of Principal, Assistant, Adjuvant and Guiding Korean Oriental Herbal Medicines) has served as a standard principle for newly developed prescription formulas as well as established ones. Despite its significance, however, this theory hasn't been thoroughly studied and covered in the academic journals of Korean Oriental Herbal Medicines (KOHM) yet. This paper inquires into the origin of the theory while presenting the definitions and functions of Principal, Assistant, Adjuvant, and Guiding KOHM. In the end, the recommended doses and number of the KOHM comprising each of Principal, Assistant, Adjuvant, and Guiding KOHM are suggested. The compatibility theory of Principal, Assistant, Adjuvant, and Guiding KOHM can be traced back to the Warring States Period during which it was recorded in the treatise of the various schools of thoughts and their exponents. The theory was firmly established as a full system in ${\ulcorner}Shinnong's\;Pharmacopoeia{\lrcorner}\;and\;{\ulcorner}Yellow\;Emperor's\;Cannon\;of\;Internal\;Medicine{\lrcorner}$. While ${\ulcorner}Shinnong's\;Pharmacopoeia{\lrcorner}$ focuses on the classification of the properties of KOHM, ${\ulcorner}Yellow\;Emperor's\;Cannon\;of\;Internal\;Medicine{\lrcorner}$ mainly deals with the principles for writing prescriptions. In this regard, it is ${\ulcorner}Yellow\;Emperor's\;Cannon\;of\;Internal\;Medicine{\lrcorner}$ that systemized the Theory of Principal, Assistant, Adjuvant, and Guiding KOHM in a real sense. Principal KOHM aims at the causes of diseases and treat main symptoms. The doses are greater than Assistant, Adjuvant and Guiding KOHM. With their comprehensive effects, Principal KOHM is a leading ingredient of any prescription formula. Assistant KOHM are similar to Principal KOHM in its natures and flavors. Although its natures, flavors as well as efficacies may slightly differ from those of Principal KOHM, Assistant KOHM strengthens the therapeutic effects, jointly working with Principal KOHM. They mainly treat accompanying diseases and symptoms. Adjuvant KOHM is divided into two types: facilitator and inhibitor. Facilitators with the similar properties to those of Principal and Assistant KOHM help strengthen the therapeutic effects. Since they usually treat accompanying symptoms or secondary accompanying symptoms (minor accompanying symptoms), there are two kinds of facilitators. (1) The first kind of facilitators assists Principal KOHM, targeting accompanying symptoms. (2) The second ones supporting Assistant KOHM are for accompanying or secondary accompanying symptoms (or minor accompanying symptoms). Inhibitors counteract and thereby complement Principal and Assistant KOHM. Some of them inhibit the side effects or toxicity of Principal KOHM for the sake of the safety of the whole prescription formula while the others generate induced interactions. Guiding KOHM can be used for two purposes: guiding and mediating. The Guiding KOHM for the former purpose leads the other KOHM in a prescription formula to the lesion. But, the Guiding KOHM for mediating coodinate and harmonize all the ingredients in a prescription formula. The number of KOHM for those Principal, Assistant, Adjuvant and Guiding KOHM and their doses are different, depending on the types of prescriptions: classical prescriptions, prescriptions after ${\ulcorner}$Treatise of Cold-Induced Diseases${\lrcorner}$ and prescriptions of Sasang Constitutions Medicines. In the case of the prescriptions after ${\ulcorner}$Treatise of Cold-Induced Diseases${\lrcorner}$, it is highly recommended to follow the view of ${\ulcorner}$Thesaurus of Korean Oriental Medicine Doctors in Chosun Dynasty${\lrcorner}$ for the number of KOHM to be used. For the doses, however, ${\ulcorner}$Elementary Course for Medicine${\lrcorner}$</T
ST-Segment Elevation Acute Myocardial Infarction Secondary to Native Aortic Valve Thrombus
김도회 한국심초음파학회 2008 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.16 No.3
Native aortic valve thrombosis is a very rare condition. We report a case of ST-segment elevation acute myocardial infarction secondary to native aortic valve thrombus in a 61-year-old woman who presented with acute chest pain. The patient had no previous precipitating factors. The patient was treated with a thrombolytic agent and subsequently recovered. On a follow-up echocardiogram, the thrombus of aortic valve disappeared. Native aortic valve thrombosis is a very rare condition. We report a case of ST-segment elevation acute myocardial infarction secondary to native aortic valve thrombus in a 61-year-old woman who presented with acute chest pain. The patient had no previous precipitating factors. The patient was treated with a thrombolytic agent and subsequently recovered. On a follow-up echocardiogram, the thrombus of aortic valve disappeared.