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김도형(DH Kim),박찬규(CK Park),란세관(SK Lan),김재욱(JU Kim),최동희(DH Choi) 대한산부인과학회 1991 Obstetrics & Gynecology Science Vol.34 No.6
Primary carcinoma of the fallopian tube is extremely rare malignant tumor of the female genital tract. Clinical aspect of 7 cases of primary adenocarcinoma of the fallopian tube are presented with the review of literature.
김동규(DK Kim),박용원(YW Park),김도형(DH Kim),최동희(DH Choi),서경(K Seo),박찬규(CK Park) 대한산부인과학회 1991 Obstetrics & Gynecology Science Vol.34 No.4
This study was undertaken at the department of Obstetrics and Gynecology, Yonsei University College of Medicine from March through August at 1988. In order to evaluate the fetal well-being during intrapartum, 125 patients with 48 cases of high risk pregnancy, 77 cases with normal pregnancy were assessed with Acoustic stimulation test(AST) immediately followed by Admission test(AT) of intrapartal fetal monitoring and the following data were observed. 1. According to the indications, PROM was most frequent with 21 cases, post-term pregnancy 4 cases, preterm labor 3 cases as decreasing in order and the 77 cases for the control group. 2. The incidence of reactivity on each tests were 86.4% for the acoustic stimulation test, 52.8% for the admission test. 3. Perinatal morbidity was assessed with use of low Apgar score. The 1 minute low Apgar score was 25.9% for the AST reactive and the 24.2% for the AT reactive group. For the nonreactive groups its were 41.2% and 32.2% respectively. The 5 minute low Apgar score, the both reactive groups revealed 1.9% and 1.5% respectively, but in the AST nonreactive group showed three times high perinatal morbidity than AT nonreactive group as 23.5% to 8.5%(p<0.01). 4. The incidence of fetal distress during labor, in AST reactive group is 25.9% and nonreactive group is 76.5% and the difference is statistically significant(p<0.01). For the AT reactive group 21.2% and for the nonreactive group 45.8% were observed and the difference is statistically significant(p<0.01). 5. Diagnostic accuracy of AST and AT in the prediction of intrapartal fetal distress were, sensitivity for the AST and AT were 31.7% and 65.8% respectively. The specificity for the AST and AT were 95.2% and 61.9% respectively. The positive predictive value for the AST and AT were 76.5 and 45.8% respectively. The negative predictive value for the AST and AT were 74.1% and 78.8% respectively. 6. Cesarean section rate, fetal distress and the perinatal morbidity were compared to the different result of AT in relation to reacive and nonreactive AST. Both reactive in AT and AST group and the AT nonreactive and AST reactive group showed low incidence of cesarean section rate compared to the both AT and AST nonreactive group as 3.0%, 2.4% and 11.8% respectively and the difference was not significant. The incidence of the fetal distress was high in the both AT and AST nonreactive group comared to the AT reactive group as 52.9%, 31.0% and 15.1% respectively(p<0.05). 5 minute low Apgar score was highly noted in both AT and AST nonreactive group compared to the AT nonreactive and AST reactive group and the both AT and AST reactive group as 23.5%, 2.4% and 1.5% respectively(p<0.01).
폐경 후 여성에서 경피적 에스트로겐 보충요법시 병행 투여된 활성형 비타민 D의 골밀도 및 골대사에 미치는 영향에 관한 연구
김성환(SW Kim),박은동(ED Park),김도형(DH Kim),김흥열(HY Kim),석원일(WI Suk),서남원(NW Seo),이상민(SM Lee),노선화(SH Noh) 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.4
To evaluate the impacts of vitamin-D on the bone mineral density and bone metabolism in the estrogen replacement 1-year trials of 3 grops: Group 1 was 35 wemen recieved the treatment with 0.5 ㎍ of vitamin D daily by oral administration, Group Ⅱ was 50 wemen recieved the treatment with 50 ㎍ of 17 β-estradiol by percutaneous administration, Group Ⅲ was 35 wemen recieved with percutaneous estrogen with daily addition of vitamin D. In all subjects, bone mineral density (BMD) of lumbar spine and femur neck, urinary calcium/creatinine ratio, and serum osteocalcin were measured before treatment and after 6 and 12 months of treatment. BMD of femur neck in Group I, Group Ⅱ and Group Ⅲ increased but not significantly compared to basal level at 6 months and/or 12 months of treatment. As for BMD of lumbar spine, it increased significantly during the treatment in Group Ⅱ and Group Ⅲ, but not in Group Ⅰ. Serum osteocalcin in Group Ⅱ and Group Ⅲ decreased significanly at 12 months of treatment compared with Group Ⅰ. Urinary calcium/creatinine ratio in Group Ⅱ, Group Ⅲ, decreased significantly at 12 months of treatment compared with Group I. From the above results, it might be suggested that combined therapy (percutaneous estrogen with daily addition of vitamin D) is more effective in post menopausal women with the protection on decreasing bone mineral density.
김보연(BY Kim),김도형(DH Kim),이정재(JJ Lee),이순곤(SG Lee),이권해(KH Lee) 대한산부인과학회 1994 Obstetrics & Gynecology Science Vol.37 No.8
The clavicle is the most frequently fractured bone in the full-term newborn during vaginal delivery. In the new-born, the breaking force may arise from compression of the shoulders during a difficult delivery at virth. An asymptomatic fracture in the neonate may be ignored. It will unite without external immobilization and any malalignment will correct itself with growth. The typical clinical signs of the clavicle fractures are diminished movement of the affected side arm. On palpation, there is local swelling, tenderness, crecipatation over the fracture site. Fracture in the middle third of the clavicle will be clearly depectied in the anterior posterior radiogram. To demonstrate fractures of the medial and lateral end of the clavicle, however, special oblique, lateral, or lordotic 40-degee cephalic tilt views may be required. This study was analized 6,158 live births, who were delivered at the Soonchunhyang university hospital from January 1991 to August 1993. The results were as follows: 1. The incidence of clavicle fracture was 0.28%(17cases), and 16 cases were in normal spontaneous vaginal delivery, only one case was occured in cesarean section. 2. The incidence of clavicle fracture by presentation was following; 15 cases of vertex presentation and 1 case of breech presentation in the vaginal delivery, 1 case of vertex presentation in secarean section. 3. The incidence of site(riht or left) of clavicle fracture was left with in 41.2%(7 cases), right site in 58.2%(10 cases), but there was no statistical difference between incidence of fracture site(right or left). 4. The incident site of clavicle fracture was at mid 1/3 in 58.8%(10 cases), inner 1/3 in 29.4%(5cases), outer 1/3 in 11.8%(2cases). 5. During vaginal delivery, the correlation between the incidence of clavicle fracture and body weight are as follows: below 3000 gm in 0.26% (3 out of 1147 cases), 3000-3500 gm in 0.28% (5 out of 1803 cases). 3500-4000 gm in 0.92%(7 out of 758 cases), above 4000 gm in 1.47%(1 out of 68 cases), the mean body weight was 3480 gm. The clavicle fracture incidence was increased as fetal body weight was increased(p
융모막 융모샘플링(C.V.S)이 임산부 혈청 alpha-Fetoptrotein치에 미치는 영향에 관한 연구
양영호(YH Yang),김도형(DH Kim),김창규(CK Kim),이명선(MS Lee),이창훈(CH Lee) 대한산부인과학회 1989 Obstetrics & Gynecology Science Vol.32 No.12
연세대학교 의과대학 산부인과학교실에 산전유전질환 진단 및 치료적 임신중절을 목적으로 내원한 56명의 환자중 27명을 대상으로 융모막 융모셈플링을 실시하엿으며 융모채취전후 MSAFP치를 측정하여 이를 임신주수, 융모채취량, 카테터 삽입회수와 비교분석하여 다음과 같은 결론은 얻었다. 1. 임신 6-12주의 주수별 MSAFP치의 중앙값은 각각 3.0, 3.0, 3.0 , 3.0, 3.7 , 5.9, 10.0 IU/ml 이었다. 2. CVS를 시행한 27예중 18예에서 (59.3%) 20%이상의 MSAFP증가를 보였고, 이중 50%이상 100%미만은 15예로 55.5%, 100%이상은 13예로 48.1%의 빈도를 보였다. 3. CVS 후의 MSAFP로부터 태아모체성 출혈량을 계산하여 60ul이상 3예, 100ul 1예의 결과 를 보였다. 4. 채취된 융모양이 많을수록 MSAFP가 증가하였다. 5. 같은 양의 융모채취에 대해 카테터 삽입회수 3-4회인 군에서 1-2회인군에비해 MSAFP의 증가폭인 컸다. 본연구결과 CVS 후의 태아모체성 출혈을 주소하기 위하여는 CVS에 충분한 경험을 가진 산 부인과 의사와 초음파 및 유전학실험실 요원간에 긴밀한 협조하에 가능한한 최소한의 카테 터 삽입회수와 검사에 필요한 최소량의 융모채취가 필요하다고 사료된다. FMH during CVS may contribute in subsequently raising the chance of abortion and even cause maternal Rh isoimmunization . Detection and quatitation of FMH could be made by determining the changes in MSAFP level by enzyme immunoassay before and 15 minutes after CVS. CVS was perfomred in 27 patients for prenatal genetic diagnosis using a flexible plastic catheter introduced transcervically under real-time ultrasonography guidance . MSAFP levels were analyzed comparatively according to their gestational weeks, amounts of villi sampled and the frequency of catheter-pass. Fifty-nine percent of these patients had an increaed MSAFP levels by 20 per cent or more. Such a rise was thought to reflect crossing of fetal blood through intervillous space upon performing CVS, A prospective correlation was obtained. The group given three to four catheter-passes had more elevated levels of MSAFP than the group given only one or two passes . In three of these patients more than 60 ul of fetal blood was transferred with only one of them presumed with more than 0.1ml of expected volume of FMH. To minimize the chance of FMH during CVS, a least amount of villi should be obtained for diagnosis with as few catheter-pass as possible.