뇌졸중환자의 동적 균형 평가를 위한 sit-to-walk의 신뢰도 연구

김다연,최종덕,기경일,Kim, Da-Yeon,Choi, Jong-Duk,Ki, Kyong-Il 대한물리치료학회 2013 대한물리치료학회지 Vol.25 No.5

Purpose: The purposes of this study were to evaluate the correlation of clinical tools for assessment of balance and ability of gait, in order to discriminate the phases of sit-to-walk movement of patients with stroke using the motion analysis system, and to investigate the reliability of the phase of sit-to-walk movement according to functional ability of patients with stroke. Methods: Twenty -one patients participated (men 17, women 4) in this study. Sit-to-walk movement of all patients was recorded by the motion analysis system. Berg Balance Scale, Timed Up and Go test, Functional Reach Test, 10 meter Walk Timed Test, and Performance-Oriented Mobility Assessment were used as functional assessment tools. Results: The results of this study showed significant correlation between the phase I, II, IV and total phase duration of sit-to-walk movement and functional assessment tools. In addition, the intraclass correlation coefficient (ICC) showed high reliability in accordance with the functional ability of patients with stroke (Pearson's r 0.93 to 1.00). Conclusion: In conclusion, there is high reliability between measures of the phase of sit-to-walk movement of chronic stroke patients and the clinical assessment tool. Results of this study suggest that measurement of the phase of sit-to-walk movement can be used significantly as an intervention and a clinical tool for patients with stroke.

Meaningful Zooment, MY HERO

김다연,배현우,박장현,설재희,이서현 한국서비스경영학회 2022 한국서비스경영학회 학술대회 Vol.2022 No.5

1인 가구를 위한 스마트 화장대 디자인 제안 - 20대 독신 여성을 중심으로

김다연,이동민 한국융합학회 2018 한국융합학회논문지 Vol.9 No.2

The purpose of this study is to recognize the necessity of smart furniture for single - person households and to suggest final design. It is assumed that smart furniture that meets the demand can be released in the future. To this end, we intend to solve the needs of the smart technology of the subject through in-depth interviews and persona establishment through demand research. Currently, the number of single-person households is expected to increase steadily and become the most important form of household composition in the future. In the future, it will be analyzed based on the in-depth interview after the target selection for the target needs research. Then, after insights are gathered through in-depth interviews, we apply the applicable smart technology to create the expected scenarios and draw conclusions about how smart furniture will function in the future. 본 연구는 1인 가구를 위한 스마트 가구의 필요성을 인식하여 연구 대상 분석 후 최종 디자인까지 제안하는 것을 목적으로 한다. 모든 연구는 1인 가구 중 주도적인 가구 및 스마트 기기 소비 행태를 보여주는 20대 독신 여성을 중심으로 한다. 기존 국내 화장대의 편향된 디자인과 인식을 고찰하며 해외 화장대와 스마트 가구의 긍정적 사례를 살펴본다. 다음으로 스마트 화장대에 대한 소비자 니즈 파악을 위해 예비 설문조사를 진행한다. 설문 진행 후 스마트 혁신 특징을 갖는 대상에 한해 심층 인터뷰를 진행하여 화장대와 융합할 스마트 기술 선호도와 개선사항을 정리한다. 이를 바탕으로 임의의 페르소나 정립 후 대상이 갖는 스마트 화장대에 대한 니즈를 해결한 가상의 시나리오를 제시한다. 결론으로 1인 가구를 위한 스마트 화장대에 적용할 스마트 기술의 우선순위와 최종 디자인을 제안한다. 소비자의 강한 혁신으로 스마트 가구의 필요성을 절감하는 시대에 위와 같은 제안은 미래의 1인 가구를 위한 스마트 화장대 산업 발전에 기여할 것으로 기대한다.

역병에 대한 Enterobacter asburiae ObRS-5 처리의 유도저항성 발현

김다연,전용희,안재형,안시현,윤영건,박인철,박진우,Kim, Dayeon,Jeon, Yong Hee,Ahn, Jea-Hyung,Ahn, Si Hyeon,Yoon, Young Gun,Park, In Cheol,Park, Jin Woo 한국환경생물학회 2020 환경생물 : 환경생물학회지 Vol.38 No.4

본 연구에서는 기 선발한 Enterobacter asburiae ObRS-5 균주를 1×10⁸ cfu mL^-1 농도로 고추에 관주 처리했을 때 Phytophthora capsici에 의한 고추역병을 74.6% 방제하는 효과가 있었다. E. asburiae ObRS-5 균주에 의한 고추역병 방제 메커니즘을 확인하기 위해 고추의 PR1, PR4 및 PR10 유전자를 특이적으로 증폭하는 프라이머를 이용하여 quantitative PCR을 수행하였다. 그 결과 E. asburiae ObRS-5 균주를 처리한 고추에서 대조구와 비교하여 상기 세 가지 유전자의 발현이 모두 높은 수준을 유지하였다. 또한 E. asburiae ObRS-5 균주는 고추의 생육을 억제하지 않으면서 ISR 반응을 유도하는 것으로 나타났다. 이러한 결과를 통하여 P. capsici이 침입할 때 E. asburiae ObRS-5 균주가 매개하는 ISR 메커니즘을 통해 Phytophthora 역병의 제어가 가능한 것으로 사료된다. Phytophthora capsici is the organism that causes Phytophthora blight which infects red pepper plants prolifically, ultimately leading to crop loss. A previous study revealed that Enterobacter asburiae ObRS-5 suppresses Phytophthora blight in both red pepper and Ligularia fischeri plants. In order to determine whether the induced systemic resistance (ISR) was triggered by pre-infection with the ObRS-5 strain, we conducted quantitative PCR using primers for PR1, PR4, and PR10, which correlate with systemic resistance in red-pepper plants. In our results, red pepper plants treated with the ObRS-5 strain demonstrated increased expression of all three systemic resistance genes when compared to controls in the glasshouse seedling assay. In addition, treatment of red peppers with the ObRS-5 strain led to reduced Phytophthora blight symptoms caused by P. capsici, whereas all control seedlings were severely affected. Perhaps most importantly, E. asburiae ObRS-5 was shown to induce the ISR response in red peppers without inhibiting growth. These results support that the defense mechanisms are triggered by ObRS-5 strain prior to infection by P. capsici and ObRS-5 strain-mediated ISR action are linked events for protection to Phytophthora blight.

Oleuropein induces apoptosis in colorectal tumor spheres via mitochondrial fission

김다연,Park Sangmi,윤지수,Jang Woong Bi,비누스,Van Le Thi Hong,Giang Ly Thanh Truong,최재우,Lim Hye ji,권상모 대한독성 유전단백체 학회 2023 Molecular & cellular toxicology Vol.19 No.2

Background 5-Fluorouracil (5-FU) has been used as a standard chemotherapeutic agent for colorectal cancer (CRC). However, chemo-resistant cancer cells can survive under chemotherapeutic regimens, resulting in cancer recurrence. Thus, a novel approach is required to overcome chemo-resistance in CRC. Objective Recently, oleuropein (OLP), an extract derived from olive leaves, has shown anticancer eff ects and induces apoptosis in cancer cells; however, the role of OLP in 5-FU-resistant cells remains to be elucidated. Therefore, we have assessed the anticancer eff ect of OLP on tumor spheres and 5-FU-resistant cells, but also synergistic eff ect in combination of OLP and 5-FU. Results Our fi ndings revealed that OLP had a marked suppressive eff ect on tumor sphere formation capacity. Annexin V-PI staining data showed that OLP-induced apoptosis occurred in a dose-dependent manner. Mitochondrial fragmentation and mitochondrial superoxide production were observed following treatment with OLP. OLP treatment drastically suppressed the metastatic potential, including cell migration ability and anchorage-independent growth capability. In addition, combination treatment with 5-FU and OLP revealed a synergistic eff ect on cell viability in DLD-1 cells and 5-FU-resistant cells. Conclusion These fi ndings showed the suppressive eff ects of OLP against the colorectal tumor spheres and 5-FU-resistant cells. In addition, these results off er the new insights into novel therapeutic strategies for combining 5-FU and OLP in patients with chemo-resistant CRC.

In vivo release of protein-loaded microcapsules using in situ -forming hydrogels for a suppression of initial burst

김다연,Waqas Iqbal,손아름,김은화,Prasamsha Panta,김재호,김문석 한국고분자학회 2013 한국고분자학회 학술대회 연구논문 초록집 Vol.2013 No.4

갇힘 사고 없는 스마트 무선전력 엘리베이터

김다연,김상민,박선호,신봉수,신용진 한국조명·전기설비학회 2022 한국조명·전기설비학회 학술대회논문집 Vol.2022 No.11

혼합 건설폐기물 처리경로별 전과정 온실가스 발생량 평가

김다연,황용우,강홍윤,문진영 한국자원리싸이클링학회 2022 資源 리싸이클링 Vol.31 No.1

우리나라는 2019년 221,102 ton/day의 건설폐기물이 발생하였으며, 그 중, 본 연구의 대상인 혼합 건설폐기물 발생량은 24,582 ton/day로 조사되었다. 나머지 건설폐기물은 98.9%의 상당히 높은 수준으로 재활용되고 있다. 폐기물 부문의 온실가스 배출량은 17.1 백만 ton CO2-eq.로 총발생량의 2.3% 정도를 차지한다. 온실가스 배출을 감축하기 위해 환경영향 저감 방법 등에 관한 관심이 점차 증대되고 있으나, 혼합 건설폐기물의 발생량은 현재까지 지속적으로 증가하고 있어 이에 대한 적절한 처리가 필요할 것으로 판단된다. 또한, 분리·선별이 어려워 매립 및 소각에 의해 처리하는 경우가 대부분이며, 단순처리보다 재활용을 위한 효율적인 방안 마련이 시급한 실정이다. 따라서, 본 연구에서는 혼합 건설폐기물의 처리경로별 온실가스 배출량 산출을 통해 환경영향을 검토하였다. 그 결과, 온실가스 발생량이 가장 높은 것은 소각단계로 나타났으며, 최적의 온실가스 저감 방안은 단순 소각처리가 아닌 재활용, 에너지회수를 통한 재활용 처리가 최적의 방안이라고 판단된다. 또한, 에너지화 단계의 온실가스 발생량은 두 번째로 높게 발생하는 것으로 나타났다. 그러나 폐기물을 에너지로 활용하여 화석연료 사용 절감을 통해 온실가스 배출량을 감축시킬 수 있다고 판단된다. 수송단계에서는 최적의 거리 설정과바이오연료 및 전기자동차 운행 등을 적용하여 온실가스 발생량을 최소화하는 것이 최적의 방안이라고 판단된다.

간호 대학생의 성 지식, 성 태도와 성 건강 간호 장애감 간의 관계

김다연,김은아,노수경,류아인,박나은,박지혜,서정민,심효정,주성민,한진실,이건정,박수민 이화여자대학교 간호과학대학 2017 이화간호학회지 Vol.- No.51

Purpose: The purpose of this study was to investigate correlation among sexual knowledge, attitude and Barriers to patient’s sexual health of nursing undergraduate students and to provide objective data to promote sexual health-care. Method: Using a descriptive correlation, 304 nursing undergraduate students were recruited through convenience random sampling from August 1st to December 20th, 2016. Data were analyzed using average, standard deviation, percentage, t-test, ANOVA, Scheffe test, Pearson’s correlation and Multiple linear regression analysis using the SPSS 21.0 program. Results: The correlation between Sexual knowledge and Sexual attitude is statistically significant(r=.289, p<.01). As the level of sexual knowledge is higher, the sexual attitude is more open. And, Sexual knowledge(r=-.307,p<.01) and Sexual attitude(r=.180,p=.002) had a negative relationship with Barriers to patient’s sexual health. Also, Sexual knowledge was the greatest influencing factor on Barriers to patient’s sexual health. Conclusion: This study showed as the level of Sexual knowledge is higher, the Sexual attitude is more open. As the degree of Sexual knowledge is lower, the Sexual attitude is more conservative, and Barriers to patient’s sexual health is more higher. Also, Sexual knowledge is the most influential factor on Barriers to patient’s sexual health.

Bacillus amyloliquefaciens GR4-5 균주의 토양 내 정량 분석

김다연,김병용,안재형,원항연,김성일,김완규,송재경 한국유기농업학회 2015 韓國有機農業學會誌 Vol.23 No.4

Bacillus amyloliquefaciens GR4-5 was isolated from the rhizosphere soil of Korean ginseng and displayed broad-spectrum suppression of ginseng root rot pathogens. The survivability of B. amyloliquefaciens GR4-5 in soil was investigated under three different conditions; indoor, outdoor ─ of which soil was put in 14 mL tube after treatment ─ and field environments. Soil samples were collected over a four- week period from three experimental designs, and assessed for 16S rRNA gene copy number by quantitative polymerase chain reaction (qPCR). In outdoor condition, the 16S rRNA gene copy number of Bacillus spp. was 8.35 log copies g soil-1 immediately after the GR4-5 treatment. Two weeks later, the 16S rRNA gene copy number of Bacillus spp. (6.70 log copies g soil-1) was similar to that of the control (6.38 log copies g soil-1). In indoor condition, the 16S rRNA gene copy number of Bacillus spp. maintained in a certain level for a longer period than those in outdoor and field. The 16S rRNA gene copy number of Bacillus spp. in field experiment was reduced faster than that of outdoor condition. Our results show that B. amyloliquefaciens GR4-5 can survive in bulk soil for 1 week, indicating its potential use as a biocontrol agent following 7 day application intervals. This study presents that outdoor microcosm system design could be a useful method to assess easily the survivability of beneficial microorganisms.