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마취전투약제 Hydroxyzine Hydrochloride 의 임상적 연구
김용조,최미란,이동기,이지수,김노식 대한마취과학회 1979 Korean Journal of Anesthesiology Vol.12 No.1
Sedative and antiemetic effect of hydroxyzine as a premedicant were studied and results were compared with a placebo and Talwin. Two hundred and fourty patients were evaluated. These patients were divided into 6 groups. There were fourty patients in each group. Group 1: Hydroxyzine 50mg. Group 2: Hydroxyzine 100mg. Group 3: Placebo. Group 4: Talwin 20mg. Group 5: Hydroxyzine 5pmg plus Talwie 20mg. Group 6: Hydroxyzine 100mg plus Talwin 20mg. The results were as follows; 1) Satisfactory sedation was ovtained in 75% with group I, in 92.5% with group 2, in 30% with group 3, in 40% with group 4, in 82. 5% With group 5, and in 97. 5% with group 6. Better results were obtained with hydroxyzine plus Talwin group than hydroxyzine anly. 2) The incidence of postoperative nausea and vomiting in recovery room, 7. 5% wlth group 7. 5 % with group 3, 20% with group 4, 5%. with group 5. There was no case of nausea and vomiting in group 2 and group 6. We obtained a significant difference in antiemetic effect between Talwin only and the Talwin plus hydroxyzine group. 3) There was no adverse change on vital signs in all cases.
구순열(口唇裂)및 구개열성형술에 시행한 마취의 임상적 관찰
김용조,최미란,이동기,김노식 대한마취과학회 1979 Korean Journal of Anesthesiology Vol.12 No.3
We experienced 450 cases of anesthesia for the operation of cleft lip and cleft palate. The observed results were as follows. 1) Ancsthetics for the operation of cleft lip were 200 cases(44.4%), cleft palate were 248 cases(55.1%), naso-ocular fistula correction and oro-ocular correction was 1 case each. 2) Sex distribution was 298 males(66.2%) and 152 females(33.8%). 3) 292 cases(66%) were under 20kg of body weight. 4) The techniques of anesthesia were NRB with Jackson-Rees' modification in 297 casea (66%) and the semiclosed circle absorption system in 153 eases(34%). 5) The main anesthetics were halothane in 431 cases(95.8%) and Valium-Dmerol in 19 cases (0. 42%) 6) The mean blood loss in palatoplasty was 6.4 ml per kg of body weight but it was 10. 7 ml per kg in the 5~10 kg of body weight group, 9. 6 ml per kg in the 10-20 kg of body weight group, and 8. 5 ml per kg in the 20~30 kg of body weight group. 66 cases (14.7%) received blood transfusion. 7) Familial incidence was found in 4.7% (21 cases). 8) Incidence of cleft lip combined with cleft palate was 42.7%(192 csses among 450 cases), and 154 cases(51.7%) were males and 88 cases(25%) were females. 9) The most common type of cleft lip was incomplete left cleft lip(30%), and of cleft palate was complete median cleft palate(52%). 10) lntraoperative anesthetic complication ocurred in 8 cases(1.8%).
최미란,이동기,박창길,김노식 대한마취과학회 1978 Korean Journal of Anesthesiology Vol.11 No.2
Remeflin is known as an analeptic which stimulates the bulbar respiratory center, thereby causing an increase in pulmonary ventilation. The author observed the effect of Remeflin upon respiration i.e. tidal volume, minute volume and respiratory rate, and circulation, i.e. blood pressure and pulse rate, in postanesthetic patients. Ventilatory and circulatory changes were measured at 2 minutes. intervals up to 30 miminutes. after intravenous injection of the drug (0. 25 mg/kg) to 40 patients in the recovery room. The results were as follows: 1) Remeflin significantly increased tidal volume and minute volume. 2) Remeflin did not significantly alter respiratory rate, blood pressure and pulse rste. 3) Improvement in the respiratory function by Remeflin was due to an increase in the depth of respiration. 4) Side effecs by Remeflin were absent except for navsea or vomiting in a few cases.