A Case of Therapy of Aerosolized Ribavirin in a Leukemia Infant with RSV Infection

권효진,오명진,이재욱,정낙균,조빈,김학기,강진한,Kwon, Hyo Jin,Oh, Myung Jin,Lee, Jae Wook,Chung, Nak Gyun,Cho, Bin,Kim, Hack Ki,Kang, Jin Han The Korean Society of Pediatric Infectious Disease 2012 Pediatric Infection and Vaccine Vol.19 No.3

RSV는 2세 미만의 소아에서 급성 하기도 감염으로 인한 입원의 주원인이다. 특히 미숙아, 선천성 심폐질환, 면역결핍이 동반된 경우 주요 위험군으로 알려져 있다. 고위험군의 소아에서 중증 RSV 감염의 경우 리바비린 흡입요법이 허가가 되어 있으나 고비용, 안전성 등의 문제로 국내 임상에서의 사용은 매우 제한적인 실정이다. 저자들은 8개월 여환이 급성 림프구성 백혈병으로 관해유도요법 항암치료 중 발생한 RSV 폐렴으로 기흉, 기종격동, 호흡부전이 동반된 중증 감염을 경험하였다. 정맥용 면역글로불린, 경구 리바비린 투여에 반응이 없어 리바비린 흡입 치료를 시행하였고, 이후 임상적 호전을 경험하였기에 보고하는 바이다. Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in infants. Life-threatening RSV infection is often reported in young children and immunocompromised hosts. Since there is no report on ribavirin therapy for RSV pneumonia in pediatric cancer patients in Korea, we report one case of RSV pneumonia that developed in an infant with acute lymphoblastic leukemia (ALL). Despite administration of oral ribavirin and intravenous immunoglobulin, the patient's respiratory distress worsened and admission to an intensive care unit was necessary. Chest x-ray showed multifocal consolidation, pneumothorax, and pneumomediastinum. Treatment with aerosolized ribavirin led to significant clinical improvement. The role of aerosolized ribavirin is still controversial, but it might have a therapeutic potential for severe RSV pneumonia in children with leukemia.

우리나라 전자적 인적자원관리(e-HRM) 정책 과정에 관한 연구

권효진,송희준 이화여자대학교 2004 사회과학연구논총 Vol.12 No.-

지식과 정보의 세기를 맞이하여 공공부문에서는 신공공관리(NPM)를 지향하는 정부개혁과 더불어 전자정부화 정책이 급속히 추진되고 있다. HRM정책에 있어서도 IT의 적극 활용을 통해 인사의 실효, 효율, 개방, 공정성을 높이고자 e-HRM이 본격화되고 있는데, 그 가운데 우리나라 공공부문 e-HRM정책의 핵심주관부처인 중앙인사위원회의 PPSS는 공무원 인상의 채용에서부터 퇴직에 이르기까지 전 과정을 단일 통합 시스템으로 처리함으로써 인사정책의 혁신을 도모하는 세계 유일의 통합인사관리시스템이라는 점에서 그 정책과정에 대한 연구가 의미를 지닌다. 총 3단계로 나누어 진행되고 있는 PPSS 정책과정의 단계별 정책내용에 대한 분석을 통해 우리나라 e-HRM 정책과정에 대하여 고찰해 보고자 한다.

Infant Pertussis and Household Transmission in Korea

권효진,Sook Kyung Yum,Ui Yoon Choi,이수영,김종현,강진한 대한의학회 2012 Journal of Korean medical science Vol.27 No.12

A recent resurgence of pertussis has raised public health concerns even in developed countries with high vaccination coverage. The aim of this study was to describe the clinical characteristics of infant pertussis, and to determine the relative importance of household transmission in Korea. The multicenter study was prospectively conducted from January 2009 to September 2011. We identified the demographic and clinical data from these patients and performed the diagnostic tests for pertussis in their household contacts. Twenty-one patients with confirmed pertussis were included in the analysis. All infections occurred in infants younger than 6 months of age (mean age, 2.5 months) who had not completed the primary DTaP vaccination except for one patient. Infants without immunization history had a significant higher lymphocytosis and longer duration of hospital stay compared to those with immunization. All were diagnosed with PCR (100%),however, culture tests showed the lowest sensitivity (42.9%). Presumed source of infection in household contacts was documented in 85.7%, mainly parents (52.6%). Pertussis had a major morbidity in young infants who were not fully immunized. Household members were responsible for pertussis transmission of infants in whom a source could be identified. The control of pertussis through booster vaccination with Tdap in family who is taking care of young infants is necessary in Korea.

전공의 공통 교육과정에 대한 요구 분석

권효진,이영미,장형주,김애리 한국의학교육학회 2015 Korean journal of medical education Vol.27 No.3

Purpose: The core curriculum in graduate medical education (GME) is an educational program that covers the minimum body of knowledge and skills that is required of all residents, regardless of their specialty. This study examined the opinions of stakeholders in GME regarding the core curriculum. Methods: A questionnaire was administered at three tertiary hospitals that were affiliated with one university; 192 residents and 61 faculty members and attending physicians participated in the survey. The questionnaire comprised six items on physician competency and the needs for a core curriculum. Questions on subjects or topics and adequate training years for each topics were asked only to residents. Results: Most residents (78.6%) and faculty members (86.9%) chose “medical expertise” as the “doctor’s role in the 21st century.” In contrast, communicator, manager, and collaborator were recognized by less than 30% of all participants. Most residents (74.1%) responded that a core curriculum is “necessary but not feasible,” whereas 68.3% of faculty members answered that it is “absolutely needed.” Regarding subjects that should be included in the core curriculum, residents and faculty members had disparate preferences— residents preferred more “management of a private clinic” and “financial management,” whereas faculty members desired “medical ethics” and “communication skills.” Conclusion: Residents and faculty members agree that residents should develop a wide range of competencies in their training. However, the perception of the feasibility and opinions on the contents of the core curriculum differed between groups. Further studies with larger samples should be conducted to define the roles and professional competencies of physicians and the needs for a core curriculum in GME.

의과대학생의 학습윤리의식 검사 도구 개발

권효진,이영미,이영희 한국의학교육학회 2013 Korean journal of medical education Vol.25 No.3

Purpose: Identifying medical students’ perceptions of and experiences with unprofessional behavior in school can help them develop and maintain higher standards of professional ethics. The aim of this study was to develop an instrument that assesses medical students’ attitudes toward academic misconduct. Methods: A draft version of the questionnaire form was developed, based on an extensive literature review and iterative discussions. The validity of the content of this draft form was evaluated by medical students, physicians, and education specialists. A total of 803 medical students answered the questionnaire. Exploratory factor analysis was performed using principal axis factoring and Varimax rotation. A confirmatory factor analysis was also conducted by root mean square error of approximation (RMSEA) and comparative fit index (CFI). The internal consistency of the scales was calculated using the Cronbach α statistic. Results: The exploratory factor analysis generated 6 factors with 29 items: scientific misconduct (8 items); irresponsibility in the class (6 items); disrespectful behavior in patient care (5 items); dishonesty in clerkship tasks (4 items); free-riding on group assignments (4 items); and irresponsibility during clerkship (2 items). After adding a single item that addressed cheating on examinations, a 30-item inventory was developed. A confirmatory factor analysis demonstrated a favorable RMSEA (0.082) and reasonable fit (CFI, 0.844). The coefficient α for each factor varied between 0.80 and 0.90. Conclusion: Our instrument is useful in identifying students’ ethical standards with regard to academics and examining the prevalence of unprofessional behavior in medical students.

의학전문직업성의 개념과 발전 방향

권효진,이영희,안덕선,Kwon, Hyojin,Lee, Younghee,Ahn, Ducksun 연세대학교 의과대학 2012 의학교육논단 Vol.14 No.1

This paper summarizes the concept of medical professionalism and presents its direction. Toward this end, the authors compare the characteristics of a professional with those of a craftsman and a technician. The authors describe the construct of medical professionalism on the assumption that knowledge and technical competence are necessary but not sufficient conditions for the professional. The construct of medical professionalism could be defined variously, depending on the time, place, or collectivity. The authors furthermore summarize cases for the development process of medical professionalism and then compare Korean medical professionalism with that of the West. Finally, the authors present the development direction of medical professionalism in Korea.

내 생애 처음 파티

권효진 한국불교사연구소 2020 문학/사학/철학 Vol.61 No.-

치안분야에서의 Big Data 활용 사례와 바람직한 공공 연구조직 설계

권효진,이장재 한국기술혁신학회 2017 한국기술혁신학회 학술대회 발표논문집 Vol.2017 No.11

최근 범죄예측, 교통관리, 신원확인 등 다양한 목적으로 치안 분야에서 ICT 기술이 개발·이용되고 있다. 사물인터넷의 등장으로 인해 생성되는 데이터의 양이 폭발적으로 증가하고 있으며, 이를 통해 만들어진 빅데이터는 범죄분석 및 예방, 치안수요의 예측, 범죄 수사에 있어서 새로운 변화를 가져올 것으로 예고되고 있다. 새롭게 부각된 치안분야에서의 빅데이터 활용 서비스 사례로는 범죄 예측 서비스, 교통 관련 서비스, 영상 분석과 통합 관제 서비스, 웨어러블 폴리스캠 활용서비스, 신원 확인(바이오 인식 기술)서비스 등이 있다. 선진국에서는 이들 서비스를 개발하고 활용하기 위한 다양한 공공 연구조직이 설립되어 운영되고 있다. 본 고에서는 치안분야에서 빅데이터를 기반으로 한 국내외 서비스 사례와 함께 이를 수용하기 위한 바람직한 공공 연구조직에 대한 논의를 전개한다.

사이버 공간에서의 아바타를 통한 자아정체성 고찰 : 중·고등학생을 대상으로

권효진 동국대학교 2006 교육문제연구 Vol.17 No.-

As the Internet advanced, it is thought that the cyberspace in the internet which is not in particular different world. Like a real world, it is possible that we form the self-existence in the cyberspace. Specially the adolescent who use the internet most plentifully will be have a meaning of self-existence in the cyberspace. The initial point of this research is the problem of the self which the adolescent form in the cyberspace. In the real world, a self-concept is represented behavior through a body and a human's gesture is an important element which explains of himself. In the cyberspace, an avatar is a tool of self-representation. An avatar may be thought the body in the cyberspace. Therefore this paper describe the adolescent's self-identity in the cyberspace, avail of their avatar. The experiment is investigation of an avatar's image and questions which relates their avatar with a questionnaire. The followings are the results. The First, a discordance degree about an avatar which represent himself between a real world and in a cyberspace is extremely lower than other avatar's discordance degree. It represent that an avatar is not other substitute them but a part of their various aspects. The second, about questions which select an resembling avatar of himself and becoming avatar, the middle and high school student's answer is significant different. Middle school students select the epicene images, but high school students select the attractive images(purity, sexy, gentle). It guess that as growing older a representing image to others consider important. The last is that a middle and high school student's recognition of the cyberspace is different. As an age is low, the adolescent value on a behavior in the cyberspace and interest in an avatar. Also behaviors and a role of himself in the cyberspace is very significant. But as growing older, they ignore an avatar and a classification between a real world and a cyberspace are clear. It is that they surely recognize a difference between a real world and a cyberspace. 독일의 '외국인교육학'은 이주외국인 노동자 유입에 수반하는 교육문제를 해결하기 위한 교육적 대응으로서 시작되었다. 외국인교육학은 오늘날 독일교육학계에서 연구ㆍ실천되고 있는 '문화간 이해교육'의 효시이다. 외국인교육학은 교육내적차원보다는 사회적 차원에서 비롯되었으며 동화교육정책의 한계를 크게 벗어나지 못했다. 문화간 이해교육은 외국인교육학의 반성에 기초해 모든 문화의 동등한 가치, 다문화성, 문화간 이해능력을 중시하며 이를 훈련시키는 것을 교육목표로 한다. 문화간 이해교육은 현재 공식교과과목으로 채택되어 있지 않지만 모든 학과수업에 다양한 형식으로 반영되는 초학과적 성격과 함께 수많은 프로젝트, 이중 언어교육 등을 통해 실시되고 있다. 독일의 문화간 이해교육의 발생과 전개 및 구체적 사례에 대한 고찰은 한국에 이주한 외국인 노동자의 인권과 그들 자녀의 교육권리를 환기시키고 구체적인 '교육문제'를 풀어 나아가는데 하나의 중요한 단서를 제공해준다. 단일문화사회에서 다문화사회로 접어드는 한국의 교육사회적 환경의 변화기에 문화간 이해교육은 중요한 교육적 주제이며 이에 대한 학문적, 교육실천적 담론이 요구된다.

Severe Osteomyelitis as a Complication of Tokyo-172 BCG Vaccination

권효진,정보현,최병민,박경운,김윤경 대한의학회 2012 Journal of Korean medical science Vol.27 No.2

The bacilli Calmette-Guérin (BCG) Tokyo-172 strain was considered to exhibit good protective efficacy with a low rate of unfavorable side effects. However, we describe a rare case of BCG osteomyelitis developed in an immunocompetent host who was given with BCG Tokyo-172 vaccine on the left upper arm by multipuncture method. A 9-month-old girl presented with progressive inability to move her right elbow and had radiographic evidence of septic elbow combined with osteomyelitis of right distal humerus. A biopsy from the site revealed chronic caseating granulomatous inflammation, positive for BCG Tokyo-172 strain on the multiplex polymerase chain reaction. The child had to undergo second surgical debridements and oral antituberculosis chemotherapy. There were no sequelae after 2 yr of follow-up. This complication, although uncommon, should be considered in the appropriate clinical setting.