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권유리,박희정 한국산업식품공학회 2022 산업 식품공학 Vol.26 No.4
The endothelium, a continuous monolayer of cells that surrounds blood vessels, has a variety of physiological roles. Chronic exposure to psychological and physical stress, oxidative stress, and inflammation activates the endothelial signaling cascade, resulting in vascular dysfunction such as vasospasm, thrombosis, and abnormal vascular proliferation. Aging is also a significant factor in vascular dysfunction, mainly developing structural and functional changes in the endothelium. The molecules involved in endothelial dysfunction are typically angiopoietin-1 (Ang-1), Tie2, and tight junction proteins. Ang-1, an oligomeric-secreted glycoprotein, is required for the correct organization and maturation of newly-formed vessels. Ang-1 binding to tyrosine kinase receptors Tie-2 leads to the phosphorylation and activation of multiple signaling pathways related to vascular permeability. Endothelial junctions are another vital target of Tie-2 activation. Nutrition and food are closely connected with vascular dysfunction and permeability. The caloric restriction prevents age-related declines in endothelial function. Dietary patterns that prioritize moderate intake of fruits and vegetables, whole grains, low-fat dairy products, and lean meats improve endothelial function in the elderly. Natural products such as Centella asiatica, Pueraria montana, and Piper retrofractum have also been shown to help inhibit endothelial dysfunction. This review provides an update on aging-related vascular dysfunction and the role of food and nutrition.
다양한 보행속도와 경사각에 대한 보행수 검출을 위한 필터링 조건과 역치의 결정
권유리,김지원,이재호,탁계래,엄광문,Kwon, Yu-Ri,Kim, Ji-Won,Lee, Jae-Ho,Tack, Gye-Rae,Eom, Gwang-Moon 대한의용생체공학회 2009 의공학회지 Vol.30 No.6
The purpose of this study is to determine optimal filtering condition and threshold for the detection of gait-cycles for various walkway slopes as well as gait velocities. Ten young healthy subjects with accelerometer system on thigh and ankle walked on a treadmill at 9 conditions (three speeds and three slopes) for 5 minutes. Two direction signals, i.e. anterior-posterior (AP) and superior-inferior (SI) directions, of each sensor (four sensor orientations) were used to detect specific events of gait cycle. Variation of the threshold (from -1G to 1G) and lowpass cutoff frequency (fc) were applied to the event detection and their performance was evaluated according to the error index (EI), which was defined as the combination of the accuracy and false positive rate. Optimal fc and threshold were determined for each slope in terms of the EI. The optimal fc, threshold and their corresponding EI depended much on the walkway slope so that their coefficients of variation (CV) ranged 19~120%. When all data for 3 slopes were used in the identification of optimal conditions for each sensor, the best error indices for all sensor orientations were comparable ranging 1.43~1.76%, but the optimal fc and threshold depended much on the sensor position. The result indicates that the gait-cycle detection robust to walkway slope is possible by threshold method with well-defined filtering condition and threshold.
행복 변동성의 차이에 관한 연구: 대학생 종단 자료를 이용한 잠재계층성장 모형 접근
권유리,최인철,최종안 한국사회및성격심리학회 2019 한국심리학회지 사회 및 성격 Vol.33 No.3
The current research aimed to explore whether and how happiness varied. While previous studies mainly focused on either the stability of happiness or the variability of happiness, we took into account the possibility that there might be differences in the patterns of variability in happiness and investigated whether happiness varied in different patterns among different people. To this end, we conducted a series of latent class growth modeling analyses with longitudinal data collected from undergraduates for three years (N = 219). The results showed that there were three different subgroups in terms of patterns of happiness change: increasing vs. stable vs. decreasing. Subsequently, the results of logistic regression analyses indicated that a few demographic variables (i.e., age and major) and Big Five traits (i.e., extroversion, emotional stability, and conscientiousness) could predict the patterns of happiness change. We discussed the implications and limitations of the current research. 본 연구는 행복의 변동 여부와 변동 양상의 차이를 알아보기 위해 실시하였다. 기존의 연구들이 행복의 평균적 변화에만 주목하여 행복을 고정된 특질 혹은 유동적 상태로 이분하여 보았던 것과 달리, 본 연구는 행복 변동 양상에서의 개인차 가능성을 고려하여, 행복의 변동이 개인에 따라 상이한 형태로 나타나는지 조사하였다. 이를 위해 3년에 걸쳐 수집된 대학생 종단 자료(N = 219)를 활용하여 행복 변화에 대한 잠재계층성장모형 분석을 실시하였다. 분석 결과, 행복 변화 유형에 따라 하위-증가형, 유지형, 그리고 감소형의 세 하위 집단이 확인되었다. 추가 로지스틱 분석 결과, 일부 인구 통계학 변인과 성격 특질 변인들이 행복 변화 유형을 예측하는 것으로 나타났다. 본 연구 결과들의 시사점 및 한계점에 대해 논하였다.
생활폐기물의 재활용과 에너지화에 따른 온실가스 감축량 산정
권유리,장윤,장용철 한국폐기물자원순환학회 2018 한국폐기물자원순환학회지 Vol.35 No.6
This study examined the potentials for greenhouse gas reduction by material recovery and energy recovery from municipal solid waste between 2017 and 2026 in Daejeon Metropolitan City (DMC), which is trying to establish a material-cycle society by constructing a waste-to-energy town by 2018. The town consists of energy recovery facilities such as a mechanical treatment facility for fluff-type solid refuse fuel (SRF) with a power generation plant and anaerobic digestion of food waste for biogas recovery. Such recycling and waste-to-energy facilities will not only reduce GHGs, but will also substitute raw materials for energy consumption. The emissions and reduction rate of GHGs from MSW management options were calculated by the IPCC guideline and EU Prognos method. This study found that in DMC, the decrease of the amount of MSW landfilled and the increase of recycling and waste-to-energy flow reduced GHGs emissions from 167,332 tonCO2 eq/yr in 2017 to 123,123 tonCO2 eq/yr in 2026. Material recycling had the highest rate of GHG reduction (-228,561 tonCO2 eq/yr in 2026), followed by the solid refuse fuels (-29,146 tonCO2 eq/yr in 2026) and biogas treatment of food waste (-3,421 tonCO2 eq/yr in 2026). This study also shows that net GHG emission was found to be -30,505 tonCO2 eq in 2017 and -105,428 tonCO2 eq, indicating a great and positive impact on future CO2 emission. Improved MSW management with increased recycling and energy recovery of material waste streams can positively contribute to GHGs reduction and energy savings. The results of this study would help waste management decision-makers clarify the effectiveness of recycling MSW, and their corresponding energy recovery potentials, as well as to understand GHG reduction by the conversion.