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CHF₃ / C₂F6 플라즈마에 의한 실리콘 표면 잔류막의 특성
권광호(K.-H. Kwon),박형호(H.-H. Park),이수민(S. M. Lee),강성준(S. J. Kang),권오준(O.-J. Kwon),김보우(B.W. Kim),성영권(Y.-K. Sung) 한국진공학회(ASCT) 1992 Applied Science and Convergence Technology Vol.1 No.1
실리콘을 CHF₃/C₂F_6 가스 플라즈마를 이용하여 식각하면 실리콘위에 탄소, 불소 및 산소로 이루어진 잔류막이 형성된다. 이 잔류막을 XPS로 분석한 결과 탄소는 C-Si, C-Si, C-C/H, C-CF_x(x≤3), C-F, C-F₂, C-F₃ 결합을 하고 있으며, 불소는 F-Si, F-C 및 F-O 결합으로 이루어져 있음을 알았다. 한편 산소는 O-Si 및 O-F 결합으로, 실리콘은 Si-Si, Si-C 및 Si-O 결합상태를 나타낸다. 잔류막의 수직분포 연구를 통하여 Si-O 및 Si-C 결합이 탄소와 불소의 결합층 아래에 존재하고, 잔류막의 표면부에 F-O 결합이 분포함을 알았다. 또한 건식식각 변수가 잔류막 형성에 미치는 영향이 조사되었으며 CHF₃/C₂F_6 가스 유량비, RF power 벚 압력 등이 잔류막의 두께, 조성비 및 잔류막의 결합상태에 영향을 미침을 알 수 있었다. Si surfaces exposed to CHF₃/C₂F_6 gas plasmas in reactive ion etching (RIE) have been characterized by X-ray photoelectron spectroscopy (XPS). CHF₃/C₂F_6 gas plasma exposure of Si surface leads to the deposition of residual film containing carbon and fluorine. The narrow scan spectra of C 1s show various bonding states of carbon as C-Si, C-Si, C-C/H, C-CF_x(x≤3), C-F, C-F₂, and C-F₃. The chemical bonding states of fluorine are described with F-Si, F-C, and F-O. And the oxygen and silicon are also detected. The effects of parameters for reactive ion etching as CHF₃/C₂F_6 gas ratio, RF power, and pressure are investigated.
권오준,손동화,최웅규,곽동주,장상희,김대곤,Kwon O-Jun,Son Dong-Hwa,Choi Ung-Kyu,Kwak Dong-Ju,Jang Sang-Hee,Kim Dae-Gon 한국축산식품학회 2004 한국축산식품학회지 Vol.24 No.3
본 연구는 원적외선 저장 쌀의 급여가 산란계에 미치는 영향을 조사하기 위하여 수행되었다. 사육 기간 중 대조구에 비해 다소 원적외선 저장 쌀의 급여가 산란계의 체중에는 큰 영향을 미치지 않았으나 난중의 무게, 난황의 무게, 난각의 두께 및 산란율에 있어서는 각각 3.6∼7.6%, 3.9∼30.2%, 5.4∼13.5%및 5.4%의 증가율을 나타내었다. This study was conducted to investigate changes of egg characteristics according to feeding of far infrared irradiated rice. The feeding of rice irradiated by far infrared rays did not affect the body weight of laying hens, but egg weight (3.6∼7.6%), yolk weight (3.9∼30.2%) and thickness of egg shell (5.4∼13.5%) together with the rate of laying eggs (5.4%) were positively increased than normal rice.
권오준,유병혁,최응규,손동화,Kwon, O-Jun,Yoo, Byung-Hyuk,Choi, Ung-Kyu,Son, Dong-Hwa 한국식품과학회 2003 한국식품과학회지 Vol.35 No.2
본 연구는 원적외선 저장쌀의 급여가 흰쥐의 생존능력에 미치는 영향을 조사하기 위하여 수행되었다. 원적외선 저장쌀은 수침시간에 따른 수분흡수량이 일반쌀에 비해 1.3배정도 많았으며, 취반후와 저장에 따른 백색도가 높게 유지되었다. 원적외선 쌀의 급여는 흰쥐의 체중변화에는 유의한 영향을 미치지 못하였다. 흰쥐의 생존능력에 미치는 영향을 조사한 결과 6주령의 경우는 일반쌀과 원적외선 저장쌀간의 생존율에 따른 유의적인 차이는 확인하지 못하였으나, 7주령과 8주령의 경우, 원적외선 저장 쌀의 급여에 따른 생존능력의 유의적인 차이를 나타낸 것으로 확인되었다. Effect of feeding far infrared-irradiated rice on survival ability of mice against drowning was investigated. Moisture absorption of far infrared-irradiated rice was about 1.3-fold higher than that of normal rice. L-Value was maintained high during cooking and storage. Weight of mice was not influenced by far infrared-irradiated rice content. No significant difference in survival abilities of mice between normal rice and far infrared-irradiated rice was shown until 1 breeding week. Significant differences in survival ability between two groups were found in 2 (9.5%) and 3 breeding weeks (7.2%).
상엽(桑葉) 추출물의 Adipogenesis 억제를 통한 항비만 활성 평가
권오준 ( O Jun Kwon ) 대한본초학회 2016 大韓本草學會誌 Vol.31 No.5
Objectives:Mori Follium (Morus alba L. leaf) has been cultivated in many Asian countries. Especially, mulberry leaf has been used as an anti-diabetic remedy in oriental medicine. However, anti-obesity effect of mulberry has not been unknown. In this study, our objectives of study is to investigate the anti-adipogenic effect of mulberry water extract (MLE) and to reveal potential molecular anti-obesity mechanism in 3T3-L1 adipocytes differentiation model. Methods : The cytotoxicity of MLE in 3T3-L1 was examined by MTT assay. Anti-adipogenic effect of MLE was evaluated by Oil Red O (ORO) staining. To elucidate the molecular mechanism, inhibitor assay was employed. The mRNA expression levels of adipogenic transcriptional factors such as PPARγ and fatty acid synthase (FAS) were analyzed by reverse transcription-polymer chain reaction (RT-PCR) analysis. Results:The MLE treatment for 24 h did not affect to the 3T3-L1 cells at concentrations of 1, 10, 100, 200, 400, 800 and 1,000 ㎍/㎖. Thus, non-toxic concentration rages of MLE were used during adipogenesis period (day -2 to 7). Intracellular lipid accumulation in MLE-treated 3T3-L1 adipocytes (day 6) were quantitatively evaluated by ORO staining. The MLE treatment significantly and dose-dependently suppressed 3T3-L1 adipogenesis by 60.42%, 38.24%, and 5.97% at 10, 100, and 200 ㎍/㎖, respectively. In addition, our inhibitor assay and RT-PCR analysis revealed that the MLE-inhibited 3T3-L1 adipogenesis through inhibition of PPARγ mediated by Wnt/β-catenin signaling pathway. Conclusions: In conclusion, these findings indicate that the MLE could be used in prevent and/or treatment of obesity-related diseases.
복령(Poria cocos) 균사체 발효쌀의 첨가가 된장의 품질에 미치는 영향
권오준 ( O Jun Kwon ),김미애 ( Mi Ae Kim ),김태완 ( Tae Wan Kim ),김대곤 ( Dae Gon Kim ),손동화 ( Dong Hwa Son ),이선호 ( Seon Ho Lee ) 한국식품저장유통학회(구 한국농산물저장유통학회) 2011 한국식품저장유통학회지 Vol.18 No.1
We investigated changes in doenjang quality upon addition of rice fermented with Poria cocos mycelium. Sensory evaluation showed that rice addition to 15% (w/w) was optimal. The content of free amino acids was 1,899.17 mg% in doenjang fermented for 90 days with P. cocos mycelium. The rice contained seven essential amino acids: leucine, valine, phenylalanine, isoleucine, lysine, threonine, and methionine. The levels of essential amino acids increased after fermentation with P. cocos mycelium. Vitamin A (7.47 RE/100 g]), Vitamin D (0.45 mg/100 g]), and Vitamin E (5.73 mg/100 g) were detected in the experimental preparation but not in the control. In terms of electron-donating ability, the highest scores were 73.8% (in a water extract) and 76% (in an ethanolic extract) of doenjang fermented with P. cocos mycelium. Nitrite-scavenging ability was higher in the ethanolic extract than in the water extract of rice fermented with P. cocos mycelium.
LDL Receptor Knockout Mouse에서 부추추출물의 죽상경화증 예방 효과
권오준 ( O Jun Kwon ),이주영 ( Jooyoung Lee ),노성수 ( Seong-soo Roh ) 대한본초학회 2016 大韓本草學會誌 Vol.31 No.2
Objectives : The present study was designed to evaluate the protective effect of Allium tuberosum (AT) extract on atherosclerosis in LDL receptor knockout (LDLr KO) mouse fed western diet. Methods : The AT was extracted 70% ethanol. The experimental groups were divided with four groups of LDLr KO mice, one group fed a normal diet and the others fed a Western diets for 8weeks. Two Western diet groups were orally administered AT extract at dosage of 100 and 300 mg/kg body weight. The body weight and food intake were measured every day. We measured levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglyceride (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and Glucose in serum. Also, effect of AT extract performed using H&E staining. Results : The AT treatment groups showed decrease in body weight and food efficiency in comparison with control group. Blood biochemistry parameters such as TG, TC, LDL, and glucose levels were increased in control group, while AT treatment groups were reduced. Also, the increased levels of ALT and AST were improved by AT extract. We confirmed that the weights of liver, kidney, subcutaneous fat, epididymal fat, kidney leaf fat, and intraabdominal fat were change in LDLr KO mice treated AT extract. In addition, histopathological changes in liver and aorta were similar to normal group. Conclusions : Based on these results, the AT extract is considered to make prevention of atherosclerosis through reduction and functional improvement of the liver and vascular endothelial cells in the body fat accumulation and lipid content in LDLr ko mouse model.