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        • KCI등재후보

          유방 고형 종괴의 출력 도플러 초음파 소견과 병리조직학적 최대 미세혈관수와의 관련성$^1$

          국신호,Guk, Sin-Ho 대한영상의학회 2002 대한영상의학회지 Vol.46 No.2

          Purpose: To compare the power Doppler ultrasonographic (PDUS) findings of angiogenesis occurring in solid breast with the histopathologic findings. Materials and Methods: Thirty-one cases of pathologically proven solid breast lesions (eight benign, 23 malignant) were retrospectively reviewed, focusing on tumor size (< 3 cm, $\geq$ 3 cm), the amount (none, mild,marked), morphology (none/linear, branching, disordered) and pattern (none/peripheral, central, penetrating), as demonstrated by power Doppler ultrasonography. We compared the PDUS findings with microscopic micro-vessel density (Max-MVD, the number of micro-vessels revealed at pathologic examination after factor - VIII staining). Statistical significance was determined using the x2-test. Results: Max-MVD tended to increase according to fumor size, but the relationship was not statistically significant. In solid breast lesions there was close correlation between the observed increase in the intensity of Doppler signals and increased Max-MVD (P < 0.05). Morphologically, branching and disordered vessels were more often seen in malignant lesions, though the relationship between this finding and increased Max-MVD was not statistically significant. Penetrating and central Doppler signals were more frequent in malignant lesions and showed close correlation with increased Max-MVD (P < 0.05). Conclusion: The increased intensity of Doppler signals and the central and penetrating pattern of solid breast lesions seen at power Doppler sonography were closely related with increases in Max-MVD. 목적: 고형 유방 종괴의 출력 도플러 초음파 소견과 병리조직학적 종양의 신생혈관의 정도를 비교하여 연관성을 알아보고자 하였다. 대상과 방법: 유방 고형 종괴 총 31예 (악성 23예,양성 8예)의 출력 초음파 소견은 종괴의 크기(<3 cm, $\geq$3 cm), 도플러 신호의 양(없음, 소량, 많음), 모양(선형, 분지형, 불규칙한형), 분포 유형 (변연성, 중심성, 침투성)으로 나누어 분석하였다. 신생혈관의 정도는 조직 표본을 Factor VIII으로 특수 염색한 후에 측정한 최대 미세혈관 수(Maximum Micro-Vessel Density; 이하 Max-MVD로 표기함)로 분석하였다. 각각의 초음파 소견이 MVD에 따라 차이가 있는지 에 대해서 알아보았고 이의 통계적 유의성은 x$^2$-test를 이용하여 검증하였다. 결과: Max-MVD와 종괴 크기와의 관계는 크기가 커질수록 Max-MVD의 수치가 증가하는 경향을 보였으나 통계적인 유의성은 없었다. 도플러 신호 양의 증가와 Max-MVD의 증가는 상관관계를 보였고 통계적으로 유의하였다 (p <0.05). Max-MVD와 도플러 신호의 모양과의 관계를 보면 악성에서 비교적 특징적으로 볼 수 있는 분지형이나 불규칙한 모양의 경우 Max-MVD의 증가와 유의적 상관관계가 없었다.Max-MVD와 도플러 신호 분포 유형사이에서는 악성에 특징적인 중심성 및 침투성의 경우 Max-MVD의 증가와 밀접한 상관관계가 있었으며 통계적으로 유의하였다(p <0.05). 결론: 유방 고형 종괴의 출력 도플러 소견에서 도플러 신호 양의 증가와 도플러 신호 분포 유형 중 중심성 및 침투성은 Max-MVD의 증가와 밀접한 연관성이 있었다.

        • KCI등재

          유방 낭성 림프관종의 유방촬영, 초음파 및 자기공명영상소견 : 1예보고

          국신호 대한영상의학회 1996 대한영상의학회지 Vol.35 No.2

          Lymphangiomas are congenital malformations that occur most commonly in the head, neck or axilla and 80-90% oflesions are detected by the age of two years. Cystic lymphangioma of the breast in a 37-year-old woman ; it showedtypical well-defined tubular and nodular opacity on mammogram, a multilocular septated anechoic mass onultrasonogram, and low and high signal intensity on T1- and T2-weighted MR images, respectively. These findingsbefore surgery indicated cystic lymphangioma.

        • KCI등재

          원시성 신경외배엽 종양의 전산화단층촬영 및 자기공명영상 소견

          국신호 대한영상의학회 1991 대한영상의학회지 Vol.27 No.4

          Cerebral primitive neuroectodermal tumor(PNET), consisting of undifferentiated primitive cells, is a neoplasm of children and young adults that occurs predominantly in the supratentorial compartment. In this report, we retrospectively reviewed and analyzed 18 CT and 6 MR findings in 18 patients with pathologically-proven PNET to discover the characteristic findings, if any. The most characteristic feature of the PNETs was a well-defined multilobular oval or round large mass with components of peripheral cystic change or calcification in the cerebral hemisphere, especially in the parietal lobe. Usually there was only minimal surrounding edema. The CT density of the tumor was iso-or slightly high density with homogeneous contrast enhancement in the solid portion and low density in the cystic area. MR findings demonstrated is0-singal intensity on both T1-weighted(T1W1) and T2-weighted(T2WI) images and dense enhancement in the solid element. The cystic portion revealed low intensity on T1W1 and high intensity on T2WI.

        • KCI등재

          유방 자기공명영상에서 STIR 영상의 유용성

          국신호,이영래,이민희,박해원,김승권,정은철,Guk, Sin-Ho,Lee, Yeong-Rae,Lee, Min-Hui,Park, Hae-Won,Kim, Seung-Gwon,Jeong, Eun-Cheol 대한영상의학회 2003 대한영상의학회지 Vol.49 No.5

          목적:유방 자기공명영상(Magnetic Resonance Imaging,이하 M R I )에서 short tau inversion recovery(이하STIR)영상의유용성을알아보고자하였다. 대상과 방법:유방 MRI 촬영 후 조직학적으로 확진된 3 6명의 환자에서 4 4예(양성 1 3예,악성 31예)의 유방병소를 대상으로 T1,T2강조,STIR,역동적 조영증강 영상을 후향적으로 분석하였다. 우선역동적 조영증강영상에서병소가 가장 잘보이는 영상을선택하여같은단면의T1,T2강조 영상과 STIR 영상과 함께 하드카피를 만들었다.역동적 조영증강 영상을 기준으로 하여 STIR, T1과 T2강조영상에서 유방 실질의 양상,병소의 발견 및 양성과 악성의 구별 여부,병소의 범위 및다발성(multifocality)여부,유도관영상을평가하였다.결과를통계적으로분석하였다. 결과:병소의 발견은 4 4예의 유방병소 중 3 3예(7 5 %)에서 STIR 영상이 T1,T2강조영상보다 우수하였으며,섬유지방성 또는 지방성 유방에서 더 우수하였다(14/14,p<0.05).STIR 영상에서의 병소의양성과악성의 구별은전 예에서불가능하였다.STIR 영상이 병소의 범위 (50%),다발성 여부(4 6 %)의 평가에는 T1과 T2강조영상과 비교해서 과장된 경우가 많았다.STIR 영상에서 유도관이잘보인경우는 18예(41 %)였다. 결론:STIR 영상은T1,T2강조영상과 비교하여병소발견에 우수하였으며특히섬유지방성또는 지방성 유방의 병소 발견에 더 우수하였다.STIR 영상에서 양성과 악성의 구별은 불가능 하였고, 병소의범위,다발성여부의평가는 T1과 T2강조영상과비교할때과장되어보였다. Purpose: To assess the usefulness of STIR (short tau inversion recovery) imaging in breast MRI (magnetic resonance imaging). Materials and Methods: We retrospectively reviewed T1- and T2-weighted (T1WI, T2WI), STIR, and dynamically enhanced images of 44 pathologically confirmed breast lesions (benign, 13; malignant, 31) in 36 patients. We selected the dynamically image which best depicted a particular lesion, and then made hard copy of the corresponding T1WI, T2WI, and STIR images. Using the dynamically enhanced image as a standard, we analysed these in terms of parenchymal pattern, lesion detectability, differentiation between benign and malignant lesions, extent, multifocality, and the ductal system. The results were statistically analyzed. Results: In 33 of 44 cases (75%), detectability was greater at STIR imaging than at T1- and T2WI, especially in fibrofatty or fatty breast (14/14 cases, p<0.05). STIR images did not always differentiate between benign and malignant lesions, and extent (50%) and multifocality (46%) were commonly exaggerated compared with T1- and T2WI. In 18 of 44 cases (41%), STIR images suggested the presence of ductal structures. Conclusion: For the detection of lesions, STIR imaging was more useful than T1- and T2WI, though STIR did not differentiate between benign and malignant lesions. The extent and multifocality of a lesion were exaggerated on STIR images, compared with T1- and T2WI.

        • KCI등재

          다발성모낭낭종증의 유방촬영 및 초음파 소견 : 1예 보고

          국신호 대한영상의학회 1997 대한영상의학회지 Vol.36 No.4

          저자들은 최근 유방에 생긴 종괴를 주조로 내원하여 수술 후 다발성모낭낭종증으로 확진된 환자에서 유방촬영술과 초음파소견으로 수술전 진단이 용이하였던 예를 보고하고자 한다. 유방촬영소견상 다발성의 얇고 균일한 벽과 크기를 같는 원형 또는 타원형의 유낭종 들(oil systs)이 석회화나 주변 조직의 변화없이 유방 실질의 변연부, 액와의 피하에 위치하 였고, 초음파소견은 유방실질내의 병변없이 경계가 명확하거나 부드러운 경계의 피하 지방 과 같거나 약간 증가된 에코를 보이는 결절들로 유방과 액와의 진피 밑의 피하지방층에서 관찰되었다. Steatocystoma multiplex, a cutaneous disorder involving the appearance of sebaceous cysts on the trunk and upper arms, is often inherited as an autosomal dominant trait. The authors present mammographic and US findings of steatocystoma multiplex in a 35-year-old woman with breast masses. On mammograms, multiple uniform thin walled round or oval shaped oil cysts were seen in the peripheral portion of the breasts and axilla, and on US, well-defined or smooth ill-defined round or oval shaped nodules were seen in the subcutaneous layer of the breasts and axilla; compared with subcutaneous fat, there was iso- or slightly increased echogenicity.

        • KCI등재

          유방낭성변화:유방암 저위험군에서의 단순 유방촬영술과 초음파소견

          국신호 대한영상의학회 1996 대한영상의학회지 Vol.34 No.1

          Purpose : We performed this study to define the characteristic mammographic and ultrasonographic findings inlower risk lesions of fibrocystic change and also tried to evaluate the role of both modalities in planning thetreatment of these lesions. Materials and Methods : We retrospectively reviewed 38 cases of mammography and 46cases of ultrasonography in biopsy proven 55 cases of fibrocystic change, histologically showing thenonproliferative pattern or proliferative pattern without atypia. We analyzed the mammographic andultrasonographic findings, final assessments, and compared the effectiveness of each modality. Results : Onmammography, there were no abnormalities in 20 cases(53%), nodules or masses in 9 cases(24%), microcalcificationsin 6 cases(16%) and asymmetric density in 5 cases(14%). On ultrasonography, there were 40 cases(87%) of focalsonographic abnormality and no abnormality in 6 cases(13%). Most focal sonographic abnormalities were smooth(40cases, 93%), well-defined(21 cases, 49%) or ill-defined(22 cases, 51%) round or oval(36 cases, 84%) shaped,homogeneous(31 cases, 67%), hypoechoic(30 cases, 65%) lesions. Final assessment revealed that only 7 cases(18%) ofmammography and 8 cases(18%) of ultrasound examinations were included into the category of indeterminate andmalignancy groups which were recomended biopsy. Mammography was excellent to demonstrate the microcalcificationsand ultrasonography was effective in depiction of the focal lesions. Conclusion : The mammography andultrasonography findings were not specific in diagnosing lower risk group of fibrocystic change. But complementarystudy of both modalities in conjunction with clinical findings will be helpful in making decinion amary biopsy,fine needle aspiration, and simple close follow up of the lesions.

        • KCI등재

          뇌동맥류의 임상적 및 방사선학적 상관관계에 대한 고찰

          국신호 대한영상의학회 1987 대한영상의학회지 Vol.23 No.2

          CT is now well established for the initial examination of the ruptured intracranial aneurysm. Aside its role in the detection of subarachnoid blood, its uses include prediction of aneurysm locaton and identification of complications. Altyough its role as an indicator of preperative prognosis is not certain, it might be expected that the extent of bleeding would correlate with the preoperative clinical grade and severityof bvasospasm. CT and angiographic findings in 34 patients with subarachnoid hemorrhage, due to proven intracranial aneurysms were analyzed for prognosticsignificance in relate with the preoperative clinical grade and severityof vasospasm. RESULT: 1. Male to female ratio was 0.9:1 and the most prevalent age group was 41 to 60 years. 2. The locations of the aneurysm, in order of frequency, were; anterior cerebral artery and anterior communicating artery aneurysm in 20 cases, middle cerebral artery in 7 cases posterior comunicating artery and internal carotid art ry in 5 cases. 3. The diameter of themost common of the intracranial aneurysm was 3 to 6 mm in 14 cases. 4 There was direct correlation between CT classification, severity of clinical grade and vasospas. 5. In conclusion, CT is useful as a prognostic indicator in intracranial aneurysm patient.

        • KCI등재

          전산화단층촬영술에 의한 소아복부종괴에관한 고찰

          국신호 대한영상의학회 1988 대한영상의학회지 Vol.24 No.1

          UItrasonography is a very useful diagnostic modality for evaluation of the pediatric abdominal masses, due to faster cheaper and no radiation harzard than CT. But CT has more advantages in assessing precise anatomic location and extent of the pathologic process and also has particular value in defining the size relationof the mass to surrounding organs and detection of lymhadenopathy. We analyzed CT features of 35 cases of pathologically proven pediatric abdominal masses for recent 2 years at Ewha Womans University Hospital. The results were as follow : 1. The most common originating site was kidney (20 cases 57.1%) followed by gastrointestinal (5 cases 14.3%) nonreal retroperitoneal (4 cases 11.4%) hepatobiliary ( 3cases 8.6%) and genital (3 cases 8,6%) in order of frequency. 2. The most common mass was hydronephrosis (11 cases 31.4%) Wilms tumor (7cases 20.0%0 neuroblastoma choledochal cyst periappendiceal abscess (3 cases 8.6% respectively) ovarian cyst (2 cases 5.7%) were next in order of frequency. 3. Male to female ratio was 4-5 and choledochal cyst and overian cyst were found only in females. The most prevalent age group was 1-3 year old (12 cases 34.3%) 4. With CT the diagnosis of hydronephrosis was easy in all cases and could evaluate of its severity renal function and obstruction site with high accuracy. 5. Wilm's tumor and neuroblastoma were relatively well differentiated by their charateristic CT features ; such as location shape marrgin midline cross calyceal appearance and calcification etc. 6. Ovarian and mensentric cysts had similar CT appearance. 7. In other pediatric abdominal masses CT provided excellent information about anatomic detail precise extent of tumor and differential diagnostic findings. So CT is useful inaging modality for the demonstration and diagnosis of abdominal mass lesions in pediatric patients.

        • KCI등재

          Legg-Calv$\acute{e}$ -Perthes 질환의 자기공명영상소견

          국신호 대한영상의학회 1992 대한영상의학회지 Vol.28 No.2

          To evaluate the role of MR in the examination of Legg-Calv -Perthes(LCP) disease, we retrospectively analysed the signal intensity of the osseous lesion, thickness of the articlar cartilage, change of surrounding soft tissue, joint effusion and femoral head containment in 32cases of LCP diseases in 27 patients. The bony lesion was limited witin the epiphysis in 19cases(59%) and extended to the Physis and metaphysis in 13cases(41%). The epiphyseal lesion showed homogeneous(26/32) or heterogenous(6/32) low signal intensity(SI) on T-1 weighted images (T1WI), and homogeneous(16/28) or heterogeneous(12/28) low SI on T-2 weighted images (T2WI). The metaphyseal lesion showed low SI (13/13) on T1WI, and low (9/11) or iso(3/11) SI on T2WI. Associated metaphyseal cyst showed low SI on T1WI and high SI on T2WI. An althought physeal involvement(13/32) was indistinct, the lesion showed increased SI on both T1 and T2WI. Thickening of articular cartilage(32/32). swelling of the ligamentum te es(7/32). synovial hypertrophy (7/32) and joint effsion(27/32) were demonstrated. Lateral subluxation of the femoral head on coronal image indicated incongruity of the femoral head in 25cases(78%). We conclude that MR is an useful tool for the diagnosis as well as treatment planning in LCP disease.

        • KCI등재

          외상성 척추골절의 전산화단층촬영에 관한 연구

          국신호 대한영상의학회 1990 대한영상의학회지 Vol.26 No.2

          The accurate diagnosis of spine fracture is important to the therapeutic decision and clinical course of patient. CT was more sensitive than any other modality in the diagnosis of spine trauma and now, CT is the method of choice for preoperative evaluation in spine fracture. A retrospective review was made of CT scans of 49 spine fracture patients, who were admitted at Ewha Womens University Hospital from January, 1986 to December, 1988. The results were as follows: 1. Male to female ratio was 2.5 : 1, and the most prevalent age was 20 to 50 years. 2. multiple level injuries were 12 cases(24.55), and the most common cause of injury was falling down (22 cases, 44.95). 3. The frequent site of spine fracture was T11 to l4 level and the most common site was the 1st lumber vertebra (13 cases, 23.25). 4. Simple compression fracture was in 11 cases (19.65), and burst fracture was in 45 cases (80.4%). Neurologic symptoms were appeared in 23 cases (15.15%) of burst fracture. 5. The mos common pattern of the retropulsed fragment in burst fracture was single midline fragment type (19 cases, 42.25) and the most common type of burst fracture was classical from (19 cases, 42.2%). 6. The degree of anterior wedging above the 50% in height of vertebra was in 10 cases (17.9%). 7. Posterior element involvement of vertebra was seen in 34 cases (60.7%) and the most common finding was lamina fracture. 8. degree of spinal canal narrowing and degree of neurological impairment is not directly correlated.

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