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윤종만(Chong Mann Yoon),범희승(Hee Seung Bom),국돈표(don Pio Kook),김성렬(Seong Rhyul Kim),양건호(Keon Ho Yang),김석빈(Suk Bin Kim) 대한소화기학회 1985 대한소화기학회지 Vol.17 No.2
N/A Esophageal carcinomas are relatively rare among those of arising in gastrointestinal tract, but are important because of the high mortality and poor prognosis they have. This report was attempted to deal with an endoscopicopathological evaluation of 114 cases which had been diagnosed as esophageal cancer in the Department of Internal Medicine, Chonnam University Hospital during the period from January 1975 to August 1984. The results were as following 1) In 114 cases of esophageal cancer, male to female ratio was 7.8: 1. The peak age incidence was the 6 th decade with 39.5% 2) The tumors located at the middle one third in 48, at the lower one third in 40, at the cardia in 17, and at the upper one third in 9 cases. 3) Endoscopically, 53 cases were elevated types, 22 cases were stenotic, the remainings were 18 depressed, 15 superficial, and 6 unclassified types in order of frequency. 4) Endoscopic biopsy positive rate was 65%, in 114 cases of esophageal cancer and there was no significant difference in the involved sites but significant difference in the endoscopic tumor types: In elevated types, biopsy positive rate was 81% and in stenotic types 36% 5) Histological classification of the esophageal cancer in our study was squamous cell carcinoma in 56 cases, adenocarcinoma in 14 cases, undifferentiated carcinoma in 3 cases, and mucinous cell carcinoma in 1 case in order of frequency. 6) The histopathological types of the non-malignant cases were normal mucosa in 23 cases (59.5%), inflammation in 8 cases(20%), dysplasia in 5 cases(12.5%), hyperplasia in 2 cases (5.0%), and ulceration in 1 case(2.5%).
만성활동성 (慢性活動性) 간질환자에서 (肝疾患者) Glycyrrhizin preparation ( Stronger Neo - minophagen C ) 의 투여효과
윤종만(Chong Mann Yoon),박종춘(Jong Chun Park),박광숙(Kwang Sook Park),범희승(Hee Seung Bom),유종선(chong Sung Rheu),박세원(Seh Won Park),국돈표(don Pio Kook),김성열(Seong Rhyull Kim) 대한소화기학회 1984 대한소화기학회지 Vol.16 No.2
N/A Glycyrrhizin, one of the active component of licorice root, has been known to have various therapeutic effects in chronic hepatitis. For the assessment of therapeutic effect of glycyrrhizin preparation, we administered 40 ml of glycyrrhizin preparation intravenously in 566 ml of dextrose solution for 8 to 12 weeks, who had no symptomatic and biochemical improvement (more than 5 fold increase compared to normal value) during recent 3months in 17 patients with chronic active hepatitis. Also, laboratory follow-up of serum transaminase, HBsAg, and serum electrolyte were repeated at intervals of 7 days. The results were as follows. 1) In 16 out of 17 patients with chronic active hepatitis, serum transaminase level decreased to half value after glycyrrhizin preparation for 8 to 12 weeks duration. 2) In 14 out of 17 patients (82%), serum transaminase dropped to 2 fold level compared to normal value after 2 to 10 weeks treatment (mean SGOT: 4.5 weeks. SGPT: 5 weeks). 3) Serum transaminase were normalized in 7 out of 17 patients(42%) after 3 to 12 weeks treatment (mean SGOT: 6. 5 weeks, SGPT: 8 weeks). 4) There was no seroconversion of HBsAg during treatment. 5) There were no signs of pseudoaldosteronism including changes of serum sodium and potassium, presence of edema or hypertension during treatment.
1980年 全南地方에 流行한 El Tor Cholera 에 關한 臨床的 觀察
李相明,鞠敦杓,金相大,朴光淑,曺局炫,柳宗善,尹鍾晩 대한감염학회 1982 감염 Vol.14 No.1
Sixty-one cases of EL Tor Cholera which prevailed in Chonnam province during the epidemics in 1980 were studied clinically. 1) 61 out of 213 diarrhea patients were confirmed as El Tor Cholera, Inaba in serotype and the highest incidence was among 5th and 8th decades male. 2) Presumptive sources of infection were as follows: raw fish(30%), meat(27%), alcohol(10%), and patient's excreta(2%). Incubation period was in the range of 2~41 hours(mean 12 hours). 3) Major clinical pictures were diarrhea(95%), vomiting(75%), myalgia(64%), dehydration(62%), hypotension(38%) and hypothermia(36%). 4) The blood pictures during the early stage showed hemoconcentration and neutrophilic leukocytosis, which was normalized during the recovery stage. Alterations in serum electrolytes in the early stage included decrease in Na and Cl concentration and increase in Ca concentration. In serum K concentration, its range was wide(2.7~6.8 mEq/L). The blood urea nitrogen level in the early stage revealed mild degree of elevation but almost of them was normalized during the recovery stage. 5) Initial fluid requirement was 1,610 ㎖(500~4,500 ㎖). 6) Duration of diarrhea was ranged from 1 to 6 days and 2 to 10 days were required for the elimination of vibrio cholera in the stool. Administration of various antibiotics curtailed the duration of positive stool culture. 7) Mortality rate in the epidemics was 3 percent(2 cases).
다발성 원발성 악성종양 : 이중복암 (二重複癌) 1예 보고 A case of double primary malignant cancer
박광숙,윤종만,장건성,국돈표,윤영근,김성열 대한소화기내시경학회 1983 Clinical Endoscopy Vol.3 No.1
This is a case report of double primary malignant cancer occurred aynchronously in the stomach and lymphoid tissue, We report this case with review of literatures about the criteria, age distribution, predisposing factor, inidence, immunity and susceptibility of the primary malignant neoplasms. This case was a 59-year-old man who had Hodgkins disease and tubular adenocarcinoma, of the stomach. The diagnoais was verified histologically, Although multiple primary neoplaas are rare, the possibility of that must be conaidered seriously, And its hereditary predisposition and other predisposing factor muat be researched with enthuaiasm.
박광숙,김성렬,박종춘,김석빈,윤종만,국돈표 대한소화기내시경학회 1984 Clinical Endoscopy Vol.4 No.1
Any foreign body in the esohagus means an acute danger because of the impending perforation followed by mediastinitis, the impending erosion of bigarteries, and impending aspiration in the care of esorhageal occlusion. Nowadays, foreign body can reliably be removed hy endoscopy, and do not perforate the wall, not changed their form. Complication at the endoscopic extraction of foreign body, that requre surgical intervention are very rare. We presented a case of esophageal foreign body complicated with esophageal ulcer in a 83 years old male.