동북지역경제발전의 산업군집 우위 연구

경협 ( Xia Jing ) 한중사회과학학회 2005 한중사회과학연구 Vol.6 No.-

산업군집은 규모의 경제, 범위의 경제, 외부경제 등이 공동으로 작용하는 과정이며, 지역경제연구의 주요 대상이다. 본 논문은 산업군집 우위에 대한 이론분석을 통해 동북지역 지역경제발전이 낙후된 원인을 해부하고 산업군집 정가(定價) 우위의 경제수리모형을 통해 계량적이고 과학적이며 체계적으로 산업군집 우위의 동북 노공업기지에 대한 의의 및 역할을 분석함으로써 정확한 정책과 방안을 제시하고자 한다.

Conversational Artificial Intelligence for Spinal Pain Questionnaire: Validation and User Satisfaction

남경협,김다영,김동환,이정환,이재일,김미정,박주영,황재현,윤상석,최병관,김민규,한인호 대한척추신경외과학회 2022 Neurospine Vol.19 No.2

Objective: The purpose of our study is to develop a spoken dialogue system (SDS) for pain questionnaire in patients with spinal disease. We evaluate user satisfaction and validated the performance accuracy of the SDS in medical staff and patients. Methods: The SDS was developed to investigate pain and related psychological issues in patients with spinal diseases based on the pain questionnaire protocol. We recognized patients’ various answers, summarized important information, and documented them. User satisfaction and performance accuracy were evaluated in 30 potential users of SDS, including doctors, nurses, and patients and statistically analyzed. Results: The overall satisfaction score of 30 patients was 5.5 ± 1.4 out of 7 points. Satisfaction scores were 5.3 ± 0.8 for doctors, 6.0 ± 0.6 for nurses, and 5.3 ± 0.5 for patients. In terms of performance accuracy, the number of repetitions of the same question was 13, 16, and 33 (13.5%, 16.8%, and 34.7%) for doctors, nurses, and patients, respectively. The number of errors in the summarized comment by the SDS was 5, 0, and 11 (5.2%, 0.0%, and 11.6 %), respectively. The number of summarization omissions was 7, 5, and 7 (7.3%, 5.3%, and 7.4%), respectively. Conclusion: This is the first study in which voice-based conversational artificial intelligence (AI) was developed for a spinal pain questionnaire and validated by medical staff and patients. The conversational AI showed favorable results in terms of user satisfaction and performance accuracy. Conversational AI can be useful for the diagnosis and remote monitoring of various patients as well as for pain questionnaires in the future.

혈액투석 환자에서 저알부민혈증이 진행성 좌심실 비대에 미치는 영향

문경협,송인숙,장혜숙,유혜승,신영태,채동완,홍창기,박정식 대한신장학회 1998 춘계학술대회 초록집 Vol.1998 No.-

Internet of Things, Digital Biomarker, and Artificial Intelligence in Spine: Current and Future Perspectives

남경협,김동환,최병관,한인호 대한척추신경외과학회 2019 Neurospine Vol.16 No.4

Recent interest in medical artificial intelligence (AI) has increased with onset of the fourth industrial revolution. Real-time monitoring of patients is an important research area of medical AI. The medical AI is very closely related to the Internet of Things (IoT), a core element of the fourth industrial revolution. Attempts to diagnose and treat patients using IoT have been already applied to patients with chronic disease such as hypertension and arrhythmia. However, in the spine, research on IoT and digital biomarkers are still in the early stages. The digital biomarker obtained by IoT devices is objective and could represent real-time, real-world, and abundant data. Based on its characteristics, IoT and digital biomarkers can also be useful in the spine. Currently, research on real-time monitoring of physical activity or spinal posture is ongoing. Therefore, the authors introduce the basic concepts of IoT and digital biomarkers, their relationship to AI, and recent trends. Current and future perspectives of IoT and digital biomarker in spine are also discussed. In the future, it is expected that IoT, digital biomarkers, and AI will lead to a paradigm shift in the diagnosis and treatment of spinal diseases.

례뇌하수체 선종과 동반되어 안상조에 발생한 지주막 낭종

남경협 ( Kyoung Hyup Nam ),차승헌 ( Seung Heon Cha ),조원호 ( Won Ho Cho ),최병관 ( Byung Kwan Choi ) 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 2012 대한뇌종양학회지 Vol.11 No.1

Objectives: Arachnoid cysts are a relatively rare pathological entity, and a suprasellar arachnoid cyst is quite rare. We report on an extremely rare case of a suprasellar arachnoid cyst associated pituitary adenoma and discuss the possible pathogenesis. Clinical Presentation: A 24-year-old man was admitted to the hospital with a history of headache, visual field defect, gait disturbance, syncope, and urinary incontinence. Computed tomography showed severe hydrocephalus. Preoperative magnetic resonance images revealed a mass lesion in the sella turcica with suprasellar extension and a coexisting large supra- and parasellar cyst. Transcranial surgery was performed for the removal of the tumor mass and cyst. Ventricle size normalized after the operation. He exhibited an uneventful recovery without neurologic deficits or endocrinologic abnor-malities. Conclusion: We present clinical, radiological, and histopathological findings and discuss the possible pathogenesis of a suprasellar arachnoid cyst associated pituitary adenoma.

선천녹내장에서 반복 시행한 섬유주절제술의 결과

민경협,신정철,김찬윤,성공제,홍영재,Kyung-Hyup Min,Jung-Chul Shin,Chan-Yun Kim,Gong-Jae Sung,Young-Jae Hong 대한안과학회 2005 대한안과학회지 Vol.46 No.12

Purpose: To investigate the surgical results of repeated trabeculectomy in primary congenital glaucoma. Methods: The authors retrospectively reviewed the data of 16 patients (23 eyes) who underwent two or more trabeculectomies with or without mitomycin C for primary congenital glaucoma between 1990 and 2004. Surgical success rate and postoperative complications were assessed. The relationship between the use of mitomycin C and the surgical outcomes was also studied. Results: Among the 23 eyes, 10 had a history of previously failed goniotomy or trabeculotomy and 6 eyes had undergone trabeculectomy more than 3 times. The overall success rate of repeated trabeculectomy was 63.9% and the success rate of the 14 eyes operated on with mitomycin C was not higher than that of the 9 eyes that did not receive mitomycin C (p=0.166). Two eyes were reported to have postoperative hypotony and there was one case of endophthalmitis after trabeculectomy; however, the use of mitomycin C did not increase the overall rate of surgical complication (p=1.00). Conclusions: Repeated trabeculectomy can be considered as a procedure to treat primary congenital glaucoma, particularly in severe cases of congenital glaucoma.

Diagnostic Value of Biopsy Techniques in Lumbar Spondylodiscitis: Percutaneous Needle Biopsy and Open Biopsy

남경협,송근성,한인호,최병관,차승헌 대한척추신경외과학회 2011 Neurospine Vol.8 No.4

objective of this study was to evaluate and compare the diagnostic value of the open biopsy technique and the percutaneous biopsy techniques in lumbar spondylodiscitis. Methods: Between January 2004 and December 2009, we retrospectively reviewed the medical records of 57 patients with infectious lumbar spondylodiscitis. The etiologic diagnosis of the infectious spondylodiscitis was obtained by two methods. Of 57 cases, twenty-seven patients underwent open biopsy and thirty patients underwent percutaneous needle biopsy including computed tomography(CT)-guided and fluoroscopy-guided needle aspiration. All biopsies were performed by experienced two neurosurgeons and one interventional radiologist. Results: Of the 57 cases radiologically consistent with spinal infection, 29(50.9%) biopsy specimens resulted in positive cultures and 28(49.1%) returned negative cultures. According to the type of biopsy techniques, the culture-positive rate was higher(p=0.005) in the open biopsy group than the percutaneous needle biopsy group. 19(70.4%) of 27 biopsy specimens were positive in the open biopsy group, and 10(33.3%) of 30 biopsy specimens were positive in the percutaneous needle biopsy group. Furthermore, the open biopsy showed higher positive culture rate than the percutaneous needle biopsy in cases with administration of empirical antibiotics although there was no statistically significant(p=0.137). Conclusions: Open biopsy should be considered for administration of organism-specific antibiotics for the successful treat- ment when percutaneous needle yield negative result. Furthermore, empirical antibiotics should be delayed until results of cultures unless the patient is severely septic, critically ill, neutropenic or neurologically compromised. Objective: The objective of this study was to evaluate and compare the diagnostic value of the open biopsy technique and the percutaneous biopsy techniques in lumbar spondylodiscitis. Methods: Between January 2004 and December 2009, we retrospectively reviewed the medical records of 57 patients with infectious lumbar spondylodiscitis. The etiologic diagnosis of the infectious spondylodiscitis was obtained by two methods. Of 57 cases, twenty-seven patients underwent open biopsy and thirty patients underwent percutaneous needle biopsy including computed tomography(CT)-guided and fluoroscopy-guided needle aspiration. All biopsies were performed by experienced two neurosurgeons and one interventional radiologist. Results: Of the 57 cases radiologically consistent with spinal infection, 29(50.9%) biopsy specimens resulted in positive cultures and 28(49.1%) returned negative cultures. According to the type of biopsy techniques, the culture-positive rate was higher(p=0.005) in the open biopsy group than the percutaneous needle biopsy group. 19(70.4%) of 27 biopsy specimens were positive in the open biopsy group, and 10(33.3%) of 30 biopsy specimens were positive in the percutaneous needle biopsy group. Furthermore, the open biopsy showed higher positive culture rate than the percutaneous needle biopsy in cases with administration of empirical antibiotics although there was no statistically significant(p=0.137). Conclusions: Open biopsy should be considered for administration of organism-specific antibiotics for the successful treat- ment when percutaneous needle yield negative result. Furthermore, empirical antibiotics should be delayed until results of cultures unless the patient is severely septic, critically ill, neutropenic or neurologically compromised.

응급 수술을 시행한 신경외상 환자들에 있어 전염성 바이러스 감염의 유병율에 대한 분석

남경협 ( Kyoung Hyup Nam ),최혁진 ( Hyuk Jin Choi ),이재일 ( Jae Il Lee ),고준경 ( Jun Kyeung Ko ),한인호 ( In Ho Han ),조원호 ( Won Ho Cho ) 대한외상학회 2015 大韓外傷學會誌 Vol.28 No.1

Purpose: The aim of this study was to estimate the seropositive prevalence of blood-borne infection in neurotrauma patients who underwent emergent surgical intervention, especially patients with hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis and human immunodefIciency virus (HIV). Methods: A retrospective review identified 559 patients with traumatic brain injury and spinal trauma who underwent emergent surgery between 2007 and 2014. We reviewed the medical records and extracted data, including age, sex, location of lesion, result of serologic tests, time interval of admission and surgery after presenting to emergency room. Serologic tests for HBV, HCV, syphilis and HIV were performed and analyzed to determine whether the seropositive results were confirmed by the surgeon before surgery. Results: The majority of the patients were male (74.6%), and the mean age was 55.4±20.2 years. Most patients underwent surgery due to traumatic brain injury (90.0%). Fifty-three patients (10.0%) showed a positive result on at least one serologic test. Seropositive rates according to pathogens were 0.5% for syphilis, 5.2% for HBV and 3.9% for HCV. No positive results were noted on the serologic tests for HIV. HBV in patients with spinal cord injury and age from 40 to 49 years were associated with high serologic positive rate, and that result was statistically significant. However, no statistically significant differences were found in the other variables. Serologic results could not confirmed before surgery in the majority of the cases (62.1%), and 10.4% of these patients showed seropositive results. Conclusion: The results of this study emphasize the importance of taking precautions and conducting rapid serologic testing in preventing the occupational transmission of blood-borne viruses to health-care workers. [ J Trauma Inj 2015; 28: 9-14 ]

원발개방각녹내장과 정상안압녹내장 환자에서의 유두주위위축

현종협 ( Jong Hyub Hyun ) , 민경협 ( Kyung Hyub Min ) , 홍영재 ( Yung Jai Hong ) , 김찬윤 ( Chan Yun Kim ) 대한안과학회 2004 대한안과학회지 Vol.45 No.10

만성 신부전으로 인한 고혈압 환자에서 Amlodipine(Norvasc^(�))의 감압효과에 대한 임상적 관찰

박광기,문경협,조정관,최기철,강영준 최신의학사 1992 最新醫學 Vol.35 No.5