브랜드에 나타난 미적 가치가 추가비용 지불의향에 미치는 영향에관한 연구 : 지각된 혁신성의 매개효과를 중심으로

고진규,김유경,이효복 한국광고학회 2017 광고학연구 Vol.28 No.1

소비 수준의 향상과 기술 수준이 평준화 된 현 시장에서 기업의 차별화를 위한 방안으로브랜드의 미적가치가 주목을 받고 있다. 하지만 브랜드로부터 소비자들이 인식하는 미적인 가치에 대한 실증적인 검증은 부족했다. 본 연구는 기존 선행 연구에서 주목받지 못했던 브랜드의 미적가치를 개념화하고 브랜드의 미적가치를 구성하는 구성개념과 이를 측정하기 위한 측정항목을 개발하는 것이 목적이다. 또한 다양한 구성 차원의 브랜드 미적가치가 미치는 소비자의 브랜드 평가에 대한 인과관계에 대한 검증을 통해서 브랜드 혁신과 부가가치 창출에 미치는미적 가치의 영향력을 검증하는 연구를 진행하고자 한다. 전문가를 대상으로 심층인터뷰를 실시하여, 최초 브랜드의 미적가치에 대한 5가지 구성차원을 가설적으로 제시하였다. 이후 설문조사를 2016년 4월 18일부터 5월 3일까지 서울 및 수도권에 거주하고 있는 351명의 학생 및 회사원들을 대상으로 진행하였다. 최초 5개 구성차원과 측정문항에 대한 타당성과 신뢰도 분석의 과정을 통해, 최종적으로 소비자가 브랜드의 미적가치에대한 인식차원으로 심미성, 실용성, 정체성, 간결성의 4가지 차원을 도출하였다. 최종 4개의 브랜드 미적 가치의 구성차원이 지각된 혁신성과 추가비용 지불 의향에 미치는영향을 검증하기 위해 구조방정식모형 분석을 진행하였다. 분석결과, 브랜드디자인의 미적가치와지각된 혁신성과 추가비용 지불의향 간의 관계가 모두 긍정적으로 나타났다. 따라서 브랜드디자인의 미적가치는 추가비용 지불의향에 직접적인 영향을 미치는 것으로 났으며, 매개변인인 지각된 혁신성을 통한 경로도 유의적으로 나타나면서 브랜드디자인의 미적가치와 추가비용 지불의향사이에 직·간접적으로 모두 영향을 미치는 것으로 나타났다. 이러한 검증 결과를 바탕으로 소비자에게 제공하는 브랜드의 가치를 타 브랜드와 차별되게인식될 수 있는 방법으로서의 브랜드의 미적가치 제안을 위한 디자인의 중요성에 대한 다양한이론과 실무적 시사점을 도출하였다. I intended to suggest frame work for aesthetic value of brand design as the measure regarded as competitiveness of the company in the phenomenon that improvement of consumption level and technology level are standardized. Especially, I tried to examine what recognition consumers actually have on aesthetic value of brand design aside from perspective of the company. Lastly, I intended to see the relation between innovativeness, that recognition level shown in aesthetic design of brand design perceived, and willingness to pay additional cost. I suggested 5 kinds of initial composition factor about aesthetic value of brand design by conducting in-depth interview of majors in 20s and experts. But, through the process of reliability analysis and factor analysis, I finally deducted 4 things(aesthetic, practicality, identity, briefness) as recognition level to aesthetic value of brand design. The survey to verify research hypothesis was conducted targeting 351 students and company workers who live in Seoul and capital area from 18th April to 3rd May in 2016. Firstly, I eventually composed measurement questions through reliability analysis, EFA(Exploratory Factor Analysis) and CFA(Confirmatory Factor Analysis). Also I used SEM(Structual Equation Modeling) to verify research hypothesis and Multiple Regression to verify relation between meaningful factors empirically. As a result of research, the relation among aesthetic value of brand design, perceived innovativeness and willingness to pay additional cost was shown all positive. Therefore, aesthetic value of brand design is shown to affect willingness to pay additional cost directly and it both directly and indirectly affects between aesthetic value of brand design and willingness to pay additional cost while the path through perceived innovativeness which is mediator variable shown significantly.

ESCO사업의 소형 열병합발전적용사례

고진규 대한설비공학회 2005 대한설비공학회 강연회 및 기타간행물 Vol.- No.-

The Effect of Oryzalin on Growth and Gravitropism in Arabidopsis Roots

Jin Gyu Go(고진규),Sun Ill Park(박선일),Soon Young Kim(김순영) 한국생명과학회 2021 생명과학회지 Vol.31 No.2

Oryzalin은 미세소관의 배열을 방해하는 dinitroaniline계 제초제이다. 미세소관과 미세섬유는 식물 세포 생장에 관여하는 세포벽을 구성하는 골격 성분이다. 또한 미세소관은 평형석의 침전에도 관여하는데, 이는 뿌리 끝에 있는 columella 세포에서 중력 인지를 조절한다. 본 연구는 애기장대 뿌리에서 에틸렌 생성을 통하여 oryzalin이 뿌리 생장과 굴중성 반응에 미치는 영향을 조사하였다. 10<SUP>-4</SUP> M oryzalin을 뿌리에 처리하면 뿌리 생장과 굴중성 반응이 완전히 억제되었다. 뿌리 생장과 굴중성 반응을 조절하는 oryzalin의 작용을 알아보기 위해 애기장대 뿌리절편에서 ethylene 생합성을 측정하였다. Oryzalin을 처리하면 ACC oxidase와 ACC synthase을 활성을 촉진하여 에틸렌 생성이 촉진되고, 증가된 ethylene은 미세소관의 배열을 변화시켜 뿌리 생장과 굴중성 반응을 억제한다. Oryzalin is a dinitroaniline herbicide that has been known to disrupt microtubules. Microtubules and microfilaments are components of cytoskeletons that are implicated in plant cell growth, which requires the synthesis of cellulose when cell walls elongate. In addition, microtubules are also involved in the sedimentation of statoliths, which regulate the perception of gravity in the columella cells of root tips. In this study, we investigated the effect of oryzalin on the growth and gravitropic response of Arabidopsis roots. The role of ethylene in oryzalin’s effect was also examined using these roots. Treatment of oryzalin at a concentration of 10<SUP>-4</SUP> M completely inhibited the roots’ growth and gravitropic response. At a concentration of 10<SUP>-6</SUP> M oryzalin, root growth was inhibited by 47% at 8 hr when compared to control. Gravitropic response was inhibited by about 38% compared to control in roots treated with 10<SUP>-6</SUP> M oryzalin for 4 hr. To understand the role of oryzalin in the regulation of root growth and gravitropic response, we measured ethylene production in root segments treated with oryzalin. It was found that the addition of oryzalin stimulated ethylene production through the activation of ACC oxidase and ACC synthase genes, which are key components in the synthesis of ethylene. From these findings, it can be inferred that oryzalin inhibits the growth and gravitropic response of Arabidopsis roots by stimulating ethylene production. The increased ethylene alters the arrangement of the microtubules, which eventually interferes with the growth of the cell wall.

Deep Learning in MR Image Processing

이두희,이진구,고진규,윤재연,류강현,남윤호 대한자기공명의과학회 2019 Investigative Magnetic Resonance Imaging Vol.23 No.2

Recently, deep learning methods have shown great potential in various tasks that involve handling large amounts of digital data. In the field of MR imaging research, deep learning methods are also rapidly being applied in a wide range of areas to complement or replace traditional model-based methods. Deep learning methods have shown remarkable improvements in several MR image processing areas such as image reconstruction, image quality improvement, parameter mapping, image contrast conversion, and image segmentation. With the current rapid development of deep learning technologies, the importance of the role of deep learning in MR imaging research appears to be growing. In this article, we introduce the basic concepts of deep learning and review recent studies on various MR image processing applications.

원발 및 전이 갑상선 유두암에서의 NA(+) /I(-) Symporter mRNA 표현양상의 임상적 의의

이은주,이성진,박현주,김상희,고진규,김성배,안일민,홍석준,박기영,김하영,공경업 대한내분비학회 1999 Endocrinology and metabolism Vol.14 No.3

Background: The iodide transport into thyroid cells is an essential step in the biosynthesis of thyroid hormones. The sodium iodide symporter (NIS) which is responsible for iodide transport was cloned recently and identified as a plasma membrane glycoprotein. Recent report suggested the absence of human NIS (hNIS) mRNA expression of papillary carcinoma in thyroid indicates absence of response on radioiodine therapy for distant metastasis. To understand the change of hNIS expression at the stage of metastasis in papillary thyroid carcinomas, we evaluated the expression levels of hNIS mRNA in primary and lymph node metastatic papillary carcinoma tissues. Methods: Seven pairs of primary and lymph node metastatic tissues were included in this study. The level of hNIS mRNA in lymph node metastatic tissues and primary tissues were evaluated by reverse transcriptase-polymerase chain reaction (RT-PCR). The level of GAPDH mRNA was used as internal control. Results: Two among 6 lymph node metastatic tissues did not show hNIS mRNA even with significant hNIS expressions in papillary carcinoma tissues in thyroid. The levels of hNIS expression of remaining 4 lymph node metastatic tissues were lower than those of corresponding primary tissues. Interestingly, one case showed no hNIS expression in primary tissue, but significant hNIS expression in lymph node metastatic tissue. There was no correlation in hNIS mRNA expression between primary and lymph node metastatic tissues. Conclusion: No correlation was found in hNIS mRNA expression between primary and lymph node metastatic tissues, suggesting the measurements of hNIS mRNA level in primary tissues may not predict therapeutic response to radioactive iodine (J Kor Soc Endocrinol 14:514-519, 1999).

정상적인 위내시경 소견을 보이는 사람의 위점막 조직에서 cagA 유전자 존재의 의의

박주상,윤광희,홍원선,남승우,민영일,정훈용,고진규,김해련,양석균,이미헌,강경훈 대한소화기학회 1998 대한소화기학회지 Vol.31 No.6

Background/Aims: It becomes clear that clinical manifestation of H. pylori infection has marked diversity mainly due to the strain diversity of H. pylori and host susceptibility. Many attempts have been made to identify the pathogenic strains of H. pylori, and have shown that the strain with the gene coding for cagA may be a pathogenic strain. To determine the role of cagA gene in the developrnent of gastroduodenal diseases, it is important to test cagA gene in gastric tissues without gross abwrmality. Methods: In a total of forty-seven persons without abnormal gastroscopic findings, the prevalence of H. pylori was determined by polymerase chain reaction (PCR), CLO test, culture, and histological examination. Genomic DNA was amplified by PCR using the primer specific for the 109-bp product of 16S rRNA gene of H. pylori. The prevalence of cagA gene was examined in 37 persons who were positive in PCR for 16S rRNA gene of H. pylori. The PCR product using primer set specific for cagA gene was a 350-bp sized and represented mid-region of cagA gene. Resnlts: Thirty-two (68.1%) out of 47 persons were infected by H. pylori. Thirty-seven (78.7%) persons showed positive PCR result for H. pylori. The cagA was identified in 28 (75.7%) among 37 H. pylori positive persons. Conclusions: The high prevalence of cagA gene in H, pylori-infeced gastric mucosa was observed in the persons with no specific gross abnormality in gastroscapic examination. These results indicate that the expression of cagA gene is common in H. pylori infected gastric mucosa in Korea. To canfirm the cytotoxie activity, the further studies using other primers are needed.

정상적인 위내시경 소견을 보이는 사람의 위점막 조직에서 cagA 유전자 존재의 의의

정훈용,강경훈,남승우,윤광회,이미헌,고진규,박주상,양석균,김해련 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.31 No.6

췌담관 합류 이상과 담관 낭종이 동반된 담낭암 1예

김진호,박소연,김명환,박원철,이호정,이성구,주영민,서동완,송병철,민영일,유교상,고진규,한상택,정세라,주연호 대한소화기내시경학회 2000 Clinical Endoscopy Vol.20 No.2

An anomalous pancreaticobiliary ductal union is a rare anomaly occurring in the biliary tract. This anomaly has been implicated as a cause of choledochal cysts, bile duct and gallbladder carcinoma, and recurrent pancreatitis. A case is herein reported of a 63 year-old woman who suffered from gallbladder cancer associated with a choledochal cyst and an anomalous pancreaticobiliary union.

위에서 발생한 과립세포종 1예

김해경,홍성수,강경훈,홍원선,민영일,정훈용,박의련,김해련,양석균,심기남,고진규 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.5

Granular cell tumors of the gastrointestinal tract are uncommon, and the esophagus is the gastrointestinal site most frequently affected. Such tumors are rarely seen in the stomach, colon, or rectum. Azzopardi first described a granular cell tumor of the stomach in 1956. Since then a few gastric granular cell tumors have been reported in corresponding literature. It is believed that there have been no reported case of a granular cell tumor of the stomach in Korea. Subsequently one case of a granular cell tumor of the stomach in 38 year-old female who complained epigastric soreness is herein reported, and was successfully managed by endoscopic resection.