말초성 안면마비 입원환자 250례에 대한 임상적 고찰

강나루,탁명림,변석미,고우신,윤화정,Kang, Na-Ru,Tark, Myoung-Rim,Byun, Soek-Mi,Ko, Woo-Shin,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2010 한방안이비인후피부과학회지 Vol.23 No.3

Objectives : This study was performed to analysis the effect of oriental medical care for inpatients with facial paralysis that had visited Dept. of Otolaryngology Oriental medical hospital Dong-eui university. Methods : From January 2008 to September 2010, a clinical study was done on 250 inpatients who were treated as facial nerve paralysis at the Dept. of Otolaryngology Oriental medical hospital Dong-eui university. This study was assessed using the chart analysis. Results : 1. The distribution of sex : female 54.8%, male 45.2%. The distribution of age was pregented that fifty to sixty was the most in 67 cases(26.8%). 2. The distribution of the period of admission : female 12.5 days, male 9.9 days. 3. The distribution of past history : hypertention(18.8%), diabetes-mellitus(10.85%), facial paralysis(9.25%), cerebrovascular disease(4.4%), liver disease(5.6%), hyperlipidemia(1.2%), otitis media(1.2%), herpes zoster(1.2%), cardiac disease(2.45%), thyroid disease(1.2%). 4. The distribution of the region of facial paralysis : Rt(55.36%), Lt(56.52%). 5. Check the mastoid pain : 66.8%(female 73.91%, male 58.04%). 6. Out of prescription(Ko-Bang, 古方), Galgeun-Tang(葛根湯) and Gaejigeogaegayoungchul-Tang was used most in each 34 cases, Daesiho-Tang(大柴胡湯) 30 cases, Galgeungabanha-Tang(葛根加半夏湯) 27 cases, Sihogaeji-Tang(柴胡桂枝湯) 14 cases, Hwanggigaejiomul-Tang 12 cases, Odu-Tang(烏頭湯) 10 cases, Chijadaehwangsi-Tang 10 cases, Gaejigagalgeun-Tang(桂枝加葛根湯) 7 cases, Banhasasim-Tang(半夏瀉心湯) 5 cases, Injinho-Tang(茵蔯蒿湯) 5 cases in order. 7. The distribution of herb group : Mahwang-Jae(麻黃劑) 31.72%, Gaeji-Jae(桂枝劑) 26.00%, Siho-Gae(柴胡劑) 20.70%, Chija-Gae(梔子劑) 7.49%, Buja-Jae(附子劑) 4.41%, Banhahwanggeum-Gae(半夏黃芩劑) 3.08%, Daehwang-Gae(大黃劑) 2.64%, Bockryeong-Gae(茯笭劑) 1.76%, Jisil-Gae(枳實劑) 1.32%, Insam-Gae(人蔘劑) 0.88% in order. 8. The distribution of House-Brackmann grade of admission : Gr Ⅳ 74.85%, Gr.III 13.6%, Gr.V 11.6% in order. 9. The distribution of House-Brackmann grade of discharge : Gr.III 56%, Gr.IV 38.4%, Gr.II 5.6% in order. 10. The average number of OPD follow up is 6.46. Conclusion : This results indicated that oriental medical treatment with Ko-bang(古方) can be an effective way to treat facial paralysis. The more patients we treat with Ko-bang(古方), the more clinical report is accumulated. Then it would be helpful to map out a systematic treatment on facial paralysis.

화폐상 습진 한방 치험 1례

탁명림,강나루,고우신,윤화정,Tark, Myoung-Rim,Kang, Na-Ru,Ko, Woo-Shin,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2011 한방안이비인후피부과학회지 Vol.24 No.2

Objective : The purpose of this study is to know the effect of Ko-Bang(古方) on nummular eczema. Methods : We decided the treatment principle through the abdominal examination and symptoms. We gave Ko-Bang to the patient and observed the progress. We used visual analogue scale(VAS). Results : After the treatment the grade of VAS was decreased and the symptoms of nummular eczema were significantly improved. Conclusion : After the treatment of Hwanggijakyakgyejigoju-Tang(黃耆芍藥桂枝苦酒湯), the symptoms of nummular eczema were disappeared and Ko-Bang was effective on the treatment of intractable skin diseases.

고방(古方)으로 치료한 두드러기 환자 39례의 임상보고(臨床報告)

탁명림,김미보,변석미,고우신,윤화정,Tark, Myoung-Rim,Kim, Mi-Bo,Byun, Seok-Mi,Ko, Woo-Shin,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2009 한방안이비인후피부과학회지 Vol.22 No.3

Objectives : This study was designed to investigate the chronical features of urticaria and the effects of urticaria treatment with Ko-Bang(古方). Methods : We treated 39 patients for urticaria with Ko-Bang(古方), who visited to care urticaria at the Dept. of Dermatology Oriental medical hospital Dong-eui university from Jan, 2008 to Sep, 2009. This study was assessed using the chart analysis and the follow-up survey by telephone. Results & Conclusions : 1. 39 outpatients were surveyed, who were 20 males and 19 females. And patients who were ages 21-30 were the largest group, 11(28.21%). Among the 39 patients, acute urticaria patients were 8(20.5%), chronic urticaria patients were 31(79.5%), and contraction of a disease period between 6 weeks with 3 months was 17.9%. 2. The causes of urticaria were measured unknown 37.5%, foods 37.5%, drugs 25% in acute and unknown 35.5%, a change of temperature 29%, foods 16% in chronic. And suspected provocation factors were measured unknown and foods each 12 cases. The most of accompanied symptoms was itching sign(34 cases), the second most was self-conscious fever(10 cases). 3. Out of treat prescription(Ko-Bang,古方), Injinho-Tang(茵蔯蒿湯) was used most in 5 cases, Daehwanghwangryunsasim-Tang(大黃黃連瀉心湯), Hwangryun-Tang(黃連湯), Daesiho-Tang(大柴胡湯) were used in each 4 cases, Galgeun-Tang(葛根湯), Chijadaehwangsi-Tang(梔子大黃?湯), Sosiho-Tang(小柴胡湯) were used in each 3 cases, Gaemagakban-Tang(桂麻各半湯), Chijasi-Tang(梔子?湯),Oryeongsan(五笭散) were used in each 2 cases. 4. When the processes of treatment were classified by one poison(一毒), there were the 19 cases (48.7%) which was caused by Bun(煩), the 12 cases(30.8%) by Water(水) and the 4 cases(10.3%) by Gyur(結).

The Effects of Jawoongo plus Rehmanniae Radix on The Wound Healing of Rats

고우신,Ko, Woo-shin The Society of Korean Medicine Ophthalmology 1999 한방안이비인후피부과학회지 Vol.12 No.1

Herbal medicines are popular in Korea communities and used for a variety of diseases, and most herbal medicines has been used an oral administration for treating diseases, but some herbal medicines included Jawoongo has been used by applying on the skin. Jawoongo, a traditional oriental medicine ointment, have been used for treating various dermatitis associated with skin diseases such as tinea manuum, eczema and chilblain, etc. by promoting blood flow(活血), dispersing wind(散風) and moistening(潤燥). Jawoongo used in this study is derived from Yungigo supplemented with Adeps Suillus(豚脂). The aim of this study is to investigate the effect of Jawoongo plus Rehmanniae Radix(生地黃) on the healing of incisional skin wound in rats. After inducing an inflammation on the rats, we observed the amount of Leukocyte, the level of Cortisol and CRP(C-reactive protein), the histological parts and have obtained the healing effect of wound by using Jawoongo plus Rehmanniae Radix(生地黃).

肛門病 中 痔의 範疇와 原因 症狀 및 治療에 對한 文獻的 考察

이상욱,고우신,Lee, Sang-uk,Ko, Woo-shin 대한한방안이비인후피부과학회 1999 한방안이비인후피부과학회지 Vol.12 No.1

In oriental medicine, 'chi(痔)' is 'the prolapsed nodule' in 'Ku-gyu(九竅)', but in this paper, I will write about prolapsed nodule only in anus or around it, chi-jil(痔疾), it called hemorrhoid in western medicine. So in the literatual studies on chi(痔) in anus or around it, the results are as follows. 1. The etiology and pathogenesis of ch.i-jil(痔疾) is wind, wetness, dryness, and heat caused by inrregular diet habit, severe drinking and sexual action, deficiency of ki(氣) and hyeol(血). 2. Characteristic symptoms of chi-jil(痔疾) is the prolapsed nodule in the anus or around it, and general symptoms are hematochezia, pain, hernia, swelling, abcess, and mucosal secretion. 3. Chi-jil(痔疾) is classified eight types by characteristic symptom, shape, etiology and pathogenesis. They are mac-chi(脈痔), jang-chi(腸痔), ki-chi(氣痔), hyeol-chi(血痔), joo-chi(酒痔), mo-chi(牡痔), bin-chi(牡痔), and loo-chi(屢痔)(or young-chi(영痔), choong-chi(蟲痔)). Additionally, they are divided into two parts, internal and external chi-jil(痔疾), as likely as classification of internal and external hemorrhoid in western medicine. 4. Treatment of chi-jil(痔疾) is two methods, internal treatment and external treatment. Internal treatment is per os herb-pharmacotheraphy, external treatment is surgical or the other external pharmacotheraphy. There are several external treatment, these are fumigation-theraphy(熏痔法). irrigation-theraphy(洗痔法), paint-theraphy(塗痔法). withering-theraphy(枯痔法), bending-therphy(結紮法) and incisal -theraphy(切開法).

멜라닌 및 색소 이상 질환과 장부(臟腑)와의 연관성 고찰

정유진,고우신,윤화정,Jung, Yu-Jin,Ko, Woo-Shin,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2016 한방안이비인후피부과학회지 Vol.29 No.3

Objectives : The purpose of this research is to understand melanin with both Korean and Western medicine.Methods : We investigated the comprehension of melanin in both western and Korean medicine through literature review and studied relationships between melanin and five viscera(五臟), especially liver(肝), spleen(脾), kidney(腎). We Also studied representative pigmentary disorders(melasma, vitiligo) in western and Korean medicine to figure out how to understand pigmentary disorders in oriental medicine.Results : The results are as follows. 1. Melanin is associate with liver, because free coursing(疎泄) function of liver is the origin of transport melanin to keratinocyte from melanocyte. Also, melanogenesis factors like MITF and CREB are closely associated with liver and pigmentary disorders occur frequently after stress conditions or women. 2. Melanin is absorbed and scattered in keratinocytes by the function of spleen. Pigmentary disorders result from failure of spleen and formation of phlegm-retained fluid(痰飮). 3. Kidney essence(腎精) is the origin of melanin formation. In addition, corticosteroid, the major hormone of melanogenesis is secreted by adrenalin and adrenalin belongs to kidney(腎) in Korean medicine. 4. Melasma is created by disorder of melanin transport and absorbtion, so melasma is associated liver (肝) and spleen(脾). Therefore the treatment for melasma may focus on improvement function of liver and spleen. 5. The destruction of melanocyte or abnormal melanogenesis by disorder of the immune system, metabolic and affective disorders can make vitiligo, so vitiligo is associated with liver and kidney which are major part of melanin formation. Therefore the treatment of vitiligo can focus on improvement function of liver(肝) and kidney(腎).Conclusion : We compared Korean and western medicine to understand melanin. We also interpreted the mechanism of melanin and pigmantary disorders in western medicine and considered the relationship with visceral manifestation theory(臟象論) in traditional Korean medicine. Further studies are needed to apply comprehension of melanin to clinical stage.

內障, 綠風內障, 靑風內障에 대한 文獻的 考察

박세봉,고우신,Park, Se-bong,Ko, Woo-shin 대한한방안이비인후피부과학회 1999 한방안이비인후피부과학회지 Vol.12 No.1

Based on the research of cataract, glaucoma, bluish glaucoma, we have abtained the following results. 1. Main etiologies of the cataract are deficiency of the liver and kidneys, main symptoms are no nebula, no pain, no tear and sometimes light blue and white vision appear. 2. Main etiologies of glaucoma are receives heat from the liver, stagnation of the liver and gall bladder etc, main symptoms are both forehead corner pull each ether, pain from eye ball to nasal septum, headache, extending pain of the eyes, sometimes red and white flower vision appear, etc. 3. main etiologies of the bluish glaucoma are melancholy, wrath, stagnation of the liver, internal damage, flaming up fire of the phlegm, deficiency of the liver, deficiency of blood, etc, main symptoms are numbness, visual field constriction, blindness, reduce of visual capacity, blue flower vision sometimes appear, etc. 4. Treatments are mainly uses nourish Um(陰) to reduce pathogenic fire, relieve stagnancy of Ki(氣) of the liver, nourish Um(陰) of the liver and kidneys, etc, acupuncture points are mostly contended arounded eyes such as BL10)(天柱), GV16(風府), LR3)(太衝), HT5)(通里) and in the case of nauses and vomitting PC6)(內關, ST36)(足三里) are included in addition to the above.

紫雲膏가 흰 쥐의 創傷에 미치는 效果

어경정,고우신,김영균,Eo, Kyeong-Jeong,Ko, Woo-Shin,Kim, Young-Kyun 대한한방안이비인후피부과학회 1998 한방안이비인후피부과학회지 Vol.11 No.1

The effects of Jawoongo on the Leukocyte Counts, Cortisol Level. CRP Level in the skin wounded rats. The results obtained as follows 1. On the Leukocyte counts in the skin wounded, sample Ⅰ, Ⅱ group were showed more significant effect than cotrol group. 2. On the Cortisol Level in the skin wounded, only sample Ⅲ group was showed continuous significant effect than control group. 3. On the CRP level in the skin wounded, sample Ⅰ, Ⅱ group were showed continuous significant effect but sample Ⅲ group was showed significant effect later on experiment. 4. On the Tissue staining in the skin wounded, was showed significant effect at all sample groups, especially sample Ⅱ,Ⅲ group of epidermis form were showed more significant effect after experimental eight days than control group. According to the above result, it is expected that Jawoongo can be applicable to the treatment of wound.

모발에 대한 동서의학적 고찰

장인욱,고우신,윤화정,Jang, In-Wook,Ko, Woo-Shin,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2016 한방안이비인후피부과학회지 Vol.29 No.4

Objectives : The purpose of this study is to compare hair and alopecia of Korean Medicine with those of western medicine. Methods : We studied relationships between hair and essense(精), qi(氣), blood(血), five vicera(五臟) and meridians(經絡) through literature review about hair and alopecia. We compared Korean medicine with western medicine on physiology of hair and treatment of alopecia based on the study. Results & Conclusion : 1. Congenital essense(先天之精) is related with genetic factor and acquired essence(後天之精) is connected with nutritional factor. Defending function of Defense qi(衛氣) is related with immune reaction and qi stagnation(氣鬱) is associated with stress reaction. Atrophy of vascular tissues observed in alopecia scalp means deep relationship between blood(血) and alopecia, further deficiency of blood can cause telogen effluvium. 2. Kidney qi(腎氣) is related with inhibiting combination of Androgen receptor and Dihydrotestosterone(DHT) or activating hair growth factior. Pi(脾) is connected with alopecia seborrheica caused by damp-heat(濕熱) and alopecia areata caused by excessive prudence(思慮過度). Heart(心) is associated with atrophy in vascular tissue of scalp and liver(肝) is connected with metabolism. 3. Armpit hair and pubic hair as secondary sex characteristics are realated with Yangming Meridian(陽明經) and beard and hair at crown part where Type II $5{\alpha}$-reductase is activated much are associated with Taiyang Meridian(太陽經). 4. Juglandis Semen pharmacopuncture and Ganoderma lucidum pharmacopucture have better effects on inhibit $5{\alpha}$-reductase than Finasteride. Minoxidil and PRP are similar with promoting blood flow and removing stasis(活血祛瘀). Seven-star needling(七星針) is similar with microneedling. 5. Alopecia can be caused by due to lack of circulation Views we need solution to improve circulation coincide in opinion with Korean Medicine and Western medicine.

녹내장의 신경 보호 치료에 대한 동서의학적 고찰

정혜진,고우신,윤화정,Jung, Hye-Jin,Ko, Woo-Shin,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2016 한방안이비인후피부과학회지 Vol.29 No.3

Objectives : The aim of this study is to understand neuroprotection therapy of glaucoma with both Korean and western medicine.Methods : We searched Pubmed on the title "glaucoma" and "neuroprotection" and also searched CNKI(China National Knowledge Infrastructure) and OASIS(Oriental Medicine Advanced Searching Integrated System) on the title "glaucoma".Results : The results are as follows. 1. In western medicine, excitotoxicity inhibition, immunomodulation, oxidative stress suppression, supplement of NTFs and stem cell therapy are studied with neuroprotection therapy of glaucoma. 2. Treatment of glaucoma in TCM and Korean medicine are associated with liver(肝) and kidney(腎).Conclusions : Korean medical approaches on neuroprotection therapy of glaucoma can be significant, and further studies are needed to research.