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고기준,신기옥,Ko, Ki-Jun,Shin, Ki-Ok Korean Society of Life Science 2007 생명과학회지 Vol.17 No.8
본 연구의 목적은 1) 캡사이신 섭취 (100 mg) 가 에너지 대사 조절자로서 열발생 교감신경활동과 관련된 자율신경활동을 향상시키는지, 2) 본 연구의 대상자들의 UCP1 과 ${\beta}_{3}$-AR 유전자 다양성이 자율신경활동에 영향을 주는지를 조사한 것이다. 8명의 대상자 (24.7 ${\pm}$ 1.8 세) 가 이 실험에 자발적으로 참여하였다. 심박수변이성 파워 스펙트랄 분석에 의해 평가된 심장자율신경활동과 에너지 대사는 총 90분간 매 30분마다 5분간 측정하였으며, 캡사이신 또는 위약 그룹은 무작위로 대상자에서 섭취되었다. 본 연구의 결과에서, 두 그룹간의 안정시 심박수에서는 유의한 차이가 없었다. 자율신경활동은 캡사이신 그룹에서 증가하였으나, 통계적으로 유의한 차이는 없었다. 총 대상자중, UCP1의 GG유전자 타입을 가진 대상자는 37.5% 였다. 그러나 캡사이신 그룹은 Test3에서 측정시 호흡 교환율이 유의하게 낮았다 (CAP: 0.80 ${\pm}$ 0.02 vs. CON: 0.85 ${\pm}$ 0.02, means ${\pm}$ SE, p<0.05). 이상의 결과로서, 캡사이신 (100 mg) 의 섭취는 지방분해를 향상시킴으로서 비만 과/또는 고지혈증을 가진 개개인에서 유익한 성분임을 시사할 수 있다. 또한 자율신경에 대한 비만과 관련된 UCP1 과/또는 ${\beta}_{3}$-AR 과 같은 유전자 다양성은 앞으로의 연구에 고려되어져야 할 것이다. We investigated whether 1) capsaicin ingestion (100 mg) enhances autonomic nervous system (ANS) activities associated with thermogenic sympathetic activity as energy metabolic modulator, 2) UCP1 and ${\beta}_{3}$-AR variants of each subjects influence with ANS activity. Eight healthy males (24.7 ${\pm}$ 1.8 yr) volunteered for this study. The cardiac autonomic nervous activities evaluated by means of heart rate variability of power spectral analysis and energy metabolism were continuously measured during 5-min rest for total 90-min resting condition with placebo or capsaicin oral administration chosen at random. The results indicated that there were no significant differences in heart rate during rest between both trials. Autonomic nervous activity increased in capsaicin tablet trial, but the difference did not reach the statistical significance. Capsaicin, however, induced significantly lower respiratory gas exchange ratio at Test3 (CAP: 0.80 ${\pm}$ 0.02 vs. 0.85 ${\pm}$ 0.02), means ${\pm}$ SE, p<0.05). In conclusion, it may be suggested the capsaicin consumption as a valuable supplement for the treatment of individual with hyperlipidemia and/or obesity by improving lipolysis. Further studies will also be considered genetic variants such as UCP1 and/or ${\beta}_{3}$-AR associated with obesity.
합숙 훈련 중 비타민 복합제 섭취가 대학 조정선수들의 면역글로불린에 미치는 영향
고기준 ( Ki Jun Ko ),신군수 ( Koon Soo Shin ),오경모 ( Kyoung Mo Oh ) 한국스포츠리서치 2007 한국 스포츠 리서치 Vol.18 No.4
The purpose of the present investigation was to evaluate the effects of 6 weeks vitamin intake on immunoglobulins during high-intensity rowing training in male university rowers. A total of 11 male rower were recruited for this study. The subjects were randomly and evenly divided into a supplemented group(SG) and a control group(CG). The supplementation consisted of capsules containing 2,400mg of vitamin C·B complex. Venous blood samples(10cc) were obtained pre-exercise and post-exercise with vitamin complex supplementation for 6 weeks. Immunoglobulin were determined by immunoturbidmetric method. Each subject performed 6 hours (AM 3 hours & PM 3 hours/day, 6days/wk, 6 weeks) rowing training program in sports complex and rowing fields. The results were expressed as mean±standard deviation(SD) by using SPSS/PC+(version 10.0) program, and the comparison of two groups (differences between groups and within group) were tested by t-test and ANCOVA with independent variables of period and group. The predetermined level of significance for the study was p≤.05. This investigation made the intensive-camp training rowers supplement the vitamin C·B complex. The conclusions of this study were as follows: 1) The vitamin supplementation group and control group showed the slight and statistically significant decrease in IgG(p<.01; p<.05). 2) The vitamin supplementation group showed the slight and statistically significant decrease in IgM(p<.01). 3) The vitamin supplementation group and control group showed the slight increase and decrease in the change of IgE, IgA and IgD, but there was no statistically significant difference. 4) In the all immunoglobulin items, no significant differences were observed between two groups in the revised mean distinction where the figures before the test are covariance.
남자 운동선수들의 VO2max와 혈청 효소 및 호르몬 반응에 관한 비교 연구
고기준(Ki Jun Ko),김태운(Tae Un Kim),이재규(Jae Gyu Lee) 한국체육교육학회 2002 한국체육교육학회지 Vol.7 No.2
The purpose of this study was to evaluate and analyze the influences of maximal oxygen consumption on hormone responses and serum enzymes activity in runners and swimmers. Six university elite runners and six university elite swimmers participated in the study after having given their informed consent. Serum LDH, GOT, GPT and testosterone, cortisol were measured in resting blood samples. And maximal oxygen consumption were measured using treadmill during maximal exercise. Statistical analyses were accomplished by using t-test to determine differences between runners and swimmers variables. Correlationship was used to determine relationships between maximal oxygen consumption and hormone, serum enzymes activity. All values presented in the text are means±SD. the significance in this study was chosen at α=.05. The conclusions obtained from this study were as follow: 1. In VO_2max per body weight, runners were significantly(P<.001) higher than swimmers. 2. In GOT, swimmers were significantly (P<.05) higher than runners, in GPT and LDH, runners were significantly(P<.05: P<.01) higher than swimmers. 3. In correlations between each variables of total athletes. significantly(P<.05) correlation were found between absolute VO_2max and cortisol. VO_2 max per body weight were significantly(P<.01: P<.05) correlated with cortisol and testosterone. And cortisol were significantly(P<.01: P<.05) correlated with testosteron. GOT, GPT and LDH. Significantly(P<.05) correlation were found between testosterone and GOT, LDH.
복합운동이 중년 비만여성들의 혈청 지질대사와 Adipocytokine에 미치는 영향
고기준(Ko, Ki-Jun) 한국사회체육학회 2014 한국사회체육학회지 Vol.0 No.58
The purpose of the present investigation was to evaluate the effects of 12 weeks exercise program participation on changes in %fat, serum lipid metabolism, leptin and adiponectin concentrations by groups in middle aged women. 20 obese women(above %fat 30) were participated in 12 weeks combined exercise program by exercise types and their %fat, leptin and adiponectin levels were assessed before program(0 week) and after program(12 weeks). Experimental groups were divided into two groups, control group(CG, n=10) and combined exercise group(EG, n=10), respectively. Regularly combined exercise(walking & resistance exercise) performed for 12 weeks. All data were expressed as mean and standard deviation by using SPSS/PC+ program, and to evaluate the differences before and after program groups, data were analyzed by paired t-test(a≤.05) and 2-way ANOVA was performed to examine the differences between groups and within groups by variables. In TC, TG and LDL-C after 12 weeks exercise program was decreased significantly in combined exercise group(p<0.05), and in HDL-C after 12 weeks exercise program was increased significantly in combined exercise group(p<0.05). In leptin response after 12 weeks exercise was decreased significantly in combined exercise group(p<0.05). In adiponectin response after 6 weeks exercise was increased significantly in combined exercise group(p<0.05). The change of leptin concentration was statistical significant difference between groups and within groups, and there was significant difference between group × period interaction(p<0.01). And the change of adiponectin concentration was statistical significant difference within groups(p<0.05). In conclusion, the regular combined(walking & resistance) exercise altered serum lipid metabolism, leptin and adiponectin responses in middle-aged obese women. Leptin and adiponectin responses to exercise training in obese women appear to be associated with body composition(body weight and %fat) alterations and exercise type(aerobic exercise or resistance training).
비타민 복합체 섭취가 조정선수들의 최대근력과 호르몬 농도에 미치는 영향
고기준(Ko, Ki-Jun) 한국체육과학회 2016 한국체육과학회지 Vol.25 No.3
The purpose of the present investigation was to evaluate the effects of vitamin C·B complex supplementation on body composition, maximal strength and hormone concentrations during highintensity rowing training in male university rowers. A total of 12 male rower were recruited for this study, and subjects were randomly and evenly divided into a supplemented(SG) group and a control(CG) group. The supplementation consisted of capsules containing 2,400mg of vitamin C·B complex. Venous blood samples(10cc) were obtained after a 24 hours overnight fast pre- and post vitamin complex supplementation for 6 we0eks. Serum hormone concentrations(growth hormone and testosterone) were determined by enzymatic methods. Maximal strength test of all subjects were bench press, squat, dead lift, power clean and two arm curls in all 1 RM by each sites, and data were collected before, after 2 weeks and 6 weeks of vitamin supplementation and training. All subjects performed 6 hours(AM 3 hours & PM 3 hours) rowing training program(gymnastics, running, power weight & power circuit, hill running, swimming, cross-country and climbing etc.; THR range 70~80%HRmax) in sports complex and rowing fields. In maximal strength before and after(2 wks & 6 wks) vitamin complex supplementation in rowers for 6 weeks, supplemented group(SG) mainly improved significantly in 1-RM variables(p<.01 or p<.05 for squat, dead lift, power clean and arm curl) by periods, but in maximal strength variables of control group there was no significant difference among the 3 experimental periods(pre, 2 wks, 6 wks). In hormone response before and after vitamin complex supplementation in rowers for 6 weeks, supplemented group(SG) increased significantly in growth hormone(p<.05) and testosterone(p<.01). And in result of 2-way ANOVA analysis for group, time, group×time, there is significant difference in time(p<.05; p<.01). Interaction effect of between group and time is difference significantly on GH(F=4.465, p<.05) and testosterone(F=6.250, p<.001) in all groups.