가르시니아 캄보지아 추출물의 지방세포 분화 및 지방 독성에 미치는 영향

강은실,함선아,황정석,이창권,서한극,Kang, Eun Sil,Ham, Sun Ah,Hwang, Jung Seok,Lee, Chang-Kwon,Seo, Han Geuk 한국축산식품학회 2013 한국축산식품학회지 Vol.33 No.3

본 연구는 가르시니아 캄보지아의 항비만 효과의 분자기전을 알아보기 위하여 지방전구세포인 3T3-L1세포의 지방세포로의 분화 시, 가르시니아 캄보지아 추출물을 처리하여 세포 내 지질 적의 형성 및 중성지방의 축적, 지방 분화 특이 지표 단백질의 발현에 미치는 영향에 대하여 살펴보았다. 3T3-L1세포의 지방 세포로의 분화는 MDI로 유도 후, 2일째부터 지방 적 및 중성 지방이 유의하게 축적되기 시작하였는데, 1% 가르시니아 캄보지아 추출물을 동시에 처리한 세포에서 이러한 지방 적 및 중성 지방의 축적이 유의하게 억제되는 것을 실험을 통해 확인할 수 있었다. 또한 지방세포 분화 특이 지표 단백질로 알려진 $PPAR{\gamma}2$, $C/EBP{\alpha}$, aP2와 같은 단백질의 발현 또한 가르시니아 캄보지아 추출물이 효과적으로 억제하고 있음도 확인할 수 있었다. 한편, 가르시니아 캄보지아 추출물은 palmitate를 처리한 HepG2 세포에서 중성지방의 축적 및 세포사멸을 유의하게 억제함으로써 유리 지방산의 축적에 의한 지속적인 염증 반응으로 유발되는 지방독성(lipotoxicity)을 억제하는 효과가 있음을 확인할 수 있었다. 이러한 결과들은 가르시니아 캄보지아 추출물이 세포 수준에서 비교적 낮은 농도로도 효과적으로 비만을 억제할 수 있으며, 기존에 알려지지 않았던 유리지방산에 의한 지방독성을 억제하는 효과가 있음을 본 연구에서 확인할 수 있었다. This study aimed to examine the mechanisms underlying the effects of Garcinia cambogia extract on the adipogenic differentiation of 3T3-L1 cells and long-chain saturated fatty acid-induced lipotoxicity of HepG2 cells. 3T3-L1 preadipocytes, mouse embryonic fibroblast-adipose like cell line, were treated with MDI solution (0.5 mM IBMX, 1 ${\mu}M$ dexamethasone, 10 ${\mu}g/mL$ insulin) to generate a cellular model of adipocyte differentiation. Using this cellular model, the anti-obesity effect of Garcinia cambogia extract was evaluated. MDI-induced lipid accumulation and expression of adipogenesis-related genes were detected by Oil red O staining, Nile Red staining, and Western blot analysis. Effects Garcinia cambogia extract on palmitate-induced lipotoxicity was also analyzed by MTT assay, LDH release, and DAPI staining in HepG2 cells. Garcinia cambogia extract significantly suppressed the adipogenic differentiation of preadipocytes and intracellular lipid accumulation in the differentiating adipocytes. Garcinia cambogia extract also markedly inhibited the expression of peroxisome proliferator- activated receptor ${\gamma}2$ ($PPAR{\gamma}2$), CCAT/enhancer-binding protein ${\alpha}$ ($C/EBP{\alpha}$), and adipocyte protein aP2 (aP2). In addition, Garcinia cambogia extract significantly attenuated palmitate-induced lipotoxicity in HepG2 cells. Palmitateinduced cellular damage and reactive aldehydes were also significantly reduced in the presence of Garcinia cambogia extract. These findings suggest that the Garcinia cambogia extract inhibits the adipogenic differentiation of 3T3-L1 preadipocytes, probably by regulating the expression of multiple genes associated with adipogenesis such as $PPAR{\gamma}2$, $C/EBP{\alpha}$, aP2, and thereby modulating fatty acid-induced lipotoxicity to reduce cellular injury in hepatocytes.

병동형 호스피스 대상자를 위한 전인적 호스피스 간호중재 프로그램의 개발

강은실,최성은,강성년,Kang, Eun-Sil,Choi, Sung-Eun,Kang, Sung-Nyun 한국호스피스협회 2007 호스피스 학술지 Vol.7 No.1

People in the end of life and their families suffer in their physical disease and other aspects as a whole person. They need hospice care to palliate their total suffering in physical, emotional, social and also spiritual aspect through professional hospice team. To care their whole personal needs, hospice team must be a multi-discipline team which consists of medical doctors, nurses, social workers, pastors and volunteers. Recently those who die in hospice palliative care unit have trend to increase more than in home year by year. So it is necessary to develop the nursing intervention program to be performed by multi-discipline team approach for in-patient of hospice palliative care unit. The purposes of this study were to develop of wholistic hospice nursing intervention program for inpatient of hospice palliative care unit. The subjects of study were collected from 30 patients those who were over 18 years old and admitted in hospice palliative care unit of S hospital in P city with agreement in hospice palliative care in their terminal disease. The period of data collection was from December 15, 2003 to March 15, 2004. The result were as follows : 1. The result of Wholistic Hospice Nursing Program's development was as follow : A Wholistic Hospice Nursing Program was developed by me in this study is one of the service program for hospice palliative care unit. It was named as ‘Rainbow Program’ to be approached easily by hospice patients. The purposes of it are to improve the quality of life of the terminal patients with their dignity, to help them live in abundant and meaningful in their lives, to care them in peaceful in dying process with understanding them in whole personal, and also to palliate the grief and suffering of the bereaved. It was provided by hospice professionals(nurses, medical doctors, social worker, pastors, art therapists) and volunteers those who were educated in hospice for multi-diciplinary team approach to collaborate with each role play I 20-30 minuters of each through visiting their rooms individually and a place of hospice palliative care unit of S hospital in P city. The subjects of it were the terminal patients those who admitted hospice palliative care unit and their familes. with agreement in hospice palliative care in their terminal disease. The characteristics of it were multi-disciplinary team approach, whole personal care, individual care and total care according to their needs in their condition. The contents of it were pain control, symptom control, counseling patient, counseling family, hair cutting, hair shampooing, bed bath, recreation, taking a walk, event of culture(screen, recital, festival of praises, exhibition and so on), pastoral counseling, ritual service in bed, praying, service in bed, sing a worship praise, listening to the music, sharing remembrance of life, individual visiting music service(sing and praying), meditation Bible, art therapies(dance and drawing), social worker's counselling, confessing and sharing love and thanksgiving. The experimental group subjects participated in Wholistic Hospice Nursing Program which takes 120 minutes per session, total 10 sessions(total 1,200 minutes) altogether. In conclusion, this Wholistic Hospice Nursing Intervention can be used actively for whole personal well-being of the patients in hospice palliative in hospice palliative care unit and also applied in hospice practice as an useful model of multi-disciplinary team approach by hospice professionals.

가르시니아 캄보지아 추출물함유 육류용 딥소스가 고지방식이 섭취 흰쥐의 지방축적 및 체중감량에 미치는 영향

강은실,황정석,김민화,김혜정,이창권,서한극,Kang, Eun Sil,Hwang, Jung Seok,Kim, Min-Hwa,Kim, Hye Jung,Lee, Chang-Kwon,Seo, Han Geuk 한국축산식품학회 2013 한국축산식품학회지 Vol.33 No.2

본 연구의 목적은 가르시니아 캄보지아 추출물이 함유된 육류용 딥소스의 항비만 효과를 동물실험을 통하여 검증하기 위하여 고지방 식이로 유도한 비만 쥐의 체중 및 지방조직의 변화, 혈중 지질성분의 변화를 5주령 흰쥐 18마리를 정상식이에 식염수 투여군(NCD), 고지방 식이에 가르시니아 캄보지아 추출물-비함유 육류용 딥소스 투여군(HFD), 고지방 식이에 2% 가르시니아 캄보지아 추출물-함유 육류용 딥소스 투여군(HFD+GC)으로 나누어 90일 간 실시하였다. HFD군의 흰쥐에서의 체중 중가가 가장 두드러지게 나타났고, 이러한 체증증가는 HFD+GC군의 흰쥐에서 유의 있게 감소되는 것을 확인할 수 있었다. 또한 개복 후 부고환 및 신장주변 지방 조직을 적출하여 무게를 확인한 결과에서도 HFD+GC군의 흰쥐에서 지방의 무게가 유의하게 감소된 것을 확인할 수 있었다. 또한, 혈청 중의 지질성분인 total cholesterol, triglycerol, total lipid의 함량이 다른 식이 군에 비해 유의하게 감소한 결과도 HFD+GC군에서 확인할 수 있었다. 이상의 결과들은 가르시니아 캄보지아 추출물이 비만 유도 실험 모델 쥐에서 비만과 관련된 각종 지표들을 억제함으로써 항비만 효과를 나타내고 있음을 확인할 수 있었고, 이러한 효과는 가르시니아 캄보지아 추출물이 함유된 육류용 딥소스를 비만을 유발할 수 있는 음식과 동시에 섭취하여도 효과가 있음이 시사되었다. Obesity, the leading metabolic disease, is a prevalent health problem in industrialized countries and is closely associated with coronary heart disease, hypertension, diabetes, and even cancer. In this study, we investigated the effects of dip-sauce for meat containing Garcinia cambogia extract (GC) on the lipid accumulation and body weight reduction in rats fed high-fat diet for three months. Eighteen Sprague Dawley male rats of five-week-old were randomly assigned to one of three groups; normal chew diet (NCD) group, high-fat diet plus GC-noncontaining dip-sauce (HFD) group, and HFD plus GC-containing dip-sauce (HFD+GC) group. Co-administration of GC-containing dip-sauce (5 g/kg body weight/day) with HFD significantly attenuated cumulative body weight gain, compared with NCD or HFD groups. Both epididymal and perirenal fat pad weights in the HFD plus GC group were significantly lower than those of HFD or NCD groups. Administration of GC-containing dip-sauce also resulted in significant reduction in the serum levels of total cholesterol, total lipid, and triglyceride, compared with NCD or HFD groups. Thus, GC-containing dip-sauce confers beneficial effects to pathological states associated with metabolic disorder via its anti-obesity and lipid lowering properties.

교회 청소년과 일반 청소년의 삶의 목적, 영적 안녕, 자아개념 및 자아 존중감 비교

강은실 ( Kang Eun Sil ),이영은 ( Lee Yeong Eun ),조향숙 ( Jo Hyang Sug ) 밴쿠버기독교세계관대학원 2003 통합연구 Vol.16 No.1

This study was carried out to compare the Purpose in life, Self-concept, Self-esteem and Spiritual well-being between in- church adolescence and out- church adolescence. Design of this study was descriptive comparative study. Object of the study were 215 adolescences of high school students in P, M city of Korea. Data was collected from 7th Nov. to 12th April using structured questionnaire. Tools of this study were PIL(Purpose in Life) developed by Crymbaugh와 Maholick(1969), scale for self- concept by Lee & Won(1995), Rosenberg s self- esteem scale translated by Choi(1972), scale for spiritual well-being of Paloutzian & Ellison translated by Choi(1990) Collected data were analyzed by frequency, percentage, chi-square test , mean, standard deviation, independent t-test , ANOVA with SPSS/PC 10.0 program. The results were as follow : 1. The results were as follow : were statistically higher than them of out-church adolescence(t=-2.759, P=.006, t=-11.082, P=.000). 2. General characteristics statistically related to the Purpose in life, Self-concept, Self-esteem and Spiritual well-being of in-church adolescence and out-church adolescence 1) General characteristics statistically related to the Purpose in life of in-church adolescence and out-church adolescence The general characteristics of in-church adolescence statistically related to the supervision of the God to my day life(F=5.513, p=.000), the degree of reading of religious books(F=7.623, p=.000), the need of religious life(F=7.872, p=.001), the Purpose in life are the influence of the religion to own`s life(F=5.175, p=.002), the degree of meditation or contemplation prayer(F=4.635, p=.002), the degree of help of the religious life or religion(F=3.055, p=.019), the degree of attendance at a religious service(F=3.202, p=.026). The general characteristics of out-church adolescence statistically relate to the degree of reading of religious books(F=7.144, p=.000), the influence of the religion to own`s life(F=8.064, p=.001), the degree of attendance at a religious service(F=5.577, p=.004), the supervision of the God to my day life(F=3.914, p=.006), the supervision of the God to my day life(F=3.914, p=.006), the religion of parents(F=3.049, p=.014), the family atmosphere(F=3.650, p=.016), the Purpose in life are the level of life(F=2.544, p=.035), the motivation of entrance into an university(F=2.744, p=.048). 2) General characteristics statistically related to Self-concept of in-church and out-church adolescence. The general characteristics statistically related to Self-concept of in-church adolescence are the family atmosphere(F=7.296, p=.000), the motivation of entrance into an university(F=4.383, p=.006), the counsel subject of one`s personal affairs(F=3.206, p=.006), the need of religious life(F=4.289, p=.016), a generation gap of parents(F=3.549, p=.016). The general characteristic statistically related to Self-concept of out-church adolescence is the family atmosphere(F=4.949, p=.003). 3) General characteristics statistically related to Self-esteem of in-church and out-church adolescence The general characteristics statistically related to the degree of Self-esteem of in-church adolescence are the family atmosphere(F=3.628, p=.008), esteem of in-church adolescence are the family religion(F=3.628, p=.008), esteem of in-church adolescence are the family university(F=2.795, p=0.43). The general characteristics statistically related to the degree of Self-esteem of out-church adolescence are a generation gap of parents(F=3.289, p=.025), the family atmosphere(F=2.810, p=.045). 4) General characteristics statistically relate to Spiritual well-being of in-church and out-church adolescence The general characteristics statistically related to Spiritual well-being of in-church adolescence are meaning of religion or God to me(F=4.900, p=.000), the influence of religion to own`s life(F=20.598, p=.000), the supervision of God to my day life(F=14.702, p=.000), th

전인건강중재 프로그램이 간호대학생의 영적안녕과 정신건강에 미치는 효과

강은실(Kang, Eun-Sil),김영희(Kim, Young-Hee),이경리(Lee, Kyung-Ri) 한국산학기술학회 2011 한국산학기술학회논문지 Vol.12 No.5

본 연구는 전인건강중재 프로그램이 간호대학생들의 영적안녕과 정신건강에 미치는 효과를 규명하기 위한 연구이다. 연구 설계는 단일군 전․ 후 실험연구이며 연구대상자는 참여를 희망하는 간호 대학생 42명을 대상으로 전 인건강중재 프로그램을 13주간 실시하였고, 수집된 자료는 빈도, paired t-test, pearson correlation coefficient로 분석하 였다. 분석한 결과는 다음과 같다. 첫째, 13주간의 전인건강중재 프로그램의 적용 전․후 영적 변화에서는 유의한 증가 를 보였다. 둘째, 13주간의 전인건강중재 프로그램을 적용한 전․ 후 간호대학생들의 정신건강의 변화는 유의하게 감소 한 것으로 나타났다. 이상의 연구 결과, 전인건강중재 프로그램은 간호대학생들의 영적안녕 및 정신건강을 향상시키 는데 효과가 있는 것으로 규명되었다. 그러므로 이 프로그램을 간호대학생들의 영적안녕 및 정신건강 증진을 위한 방 안으로 활용하여 간호실무 교육과정 개발에 필요한 기초자료로 제공되기를 기대한다. The purpose of this study is to examine the effects of Holistic Health Program on spiritual well-being and mental health of nursing students. A one-group pretest-posttest research design was used. The subjects were 42 nursing students attending C College located in Y city. All subjects participated in 13 week holistic health program. The data were analyzed using frequency, paired t-test, Pearson correlation coefficient. The results of this study were as followings; First, the score of spiritual well-being was significantly increased after Holistic Health Program in the subjects. Second, the score of mental heath was significantly increased after Holistic Health Program in the subjects. Based on these results, it was concluded that Holistic Health Program is effective for improving spiritual well-being and mental health of nursing students. Therefore, we recommend this program to be utilized as an effective method for improving spiritual well-being and mental health of nursing students. And this results will provide basic data to develop nursing practice curriculum in the nursing college.

성경적 관점에서 본 남북통일 : 일반논문 ; 간호대학생의 영적안녕에 관한 연구

강은실 ( Eun Sil Kang ),강성년 ( Seong Nyun Kang ),최성은 ( Sung Eun Choi ),김숙자 ( Sook Ja Kim ) 통합연구학회 2005 통합연구 Vol.18 No.1

청소년의 자살의도, 우울, 영적 안녕과의 관계

강은실 ( Eun Sil Kang ),송양숙 ( Yang Sook Song ),조향숙 ( Hang Suk Cho ),강성년 ( Sung Nyun Kang ) 한국정신간호학회 2004 정신간호학회지 Vol.13 No.2

N/A This study was carried out to identify the relationships of suicidal ideation, depression, spiritual well-being of adolescence in Korea. Design of the study was correlational study. Objects of the study were 423 adolescences of high school students of 5 cities in Korea, Data was collected from April, 2003 to July, 2003 using structured questionnaire. Research tools of this study were SSI(scale for suicidal ideation) developed by Beck(1979), BDI(Beck depression inventory) translated by Lee(1993), scale for spiritual well-being of Paloutzian & Ellison translated by Choi(1990) Collected data were analyzed by frequency, percentage, mean, standard deviation, t-test, ANOVA, Pearson`s correlational coefficients with SPSS/PC 11.0 program. The results of the study were as follow : 1. Mean value of suicidal ideation(25.93) of adolescences were moderate level, depression(12.48) was low, spiritual wll-being(75.35) was high. 2. Relationships of the suicidal ideation, depression, spiritual well-being of adolescence. Suicidal ideation of adolescence was positive relationships with depression(r=.628, p= .000), suicidal ideation of adolescence was negative relationships with spiritual well-being(r=-.329, p= .000). In conclusion, it was found that depression of adolescence was incline to increase suicidal ideation, spiritual well-being to decrease suicidal ideation of adolescence. Therefore, development of counseling and guidance program to increase spiritual well-being of the adolescence was suggested.

청소년의 삶의 목적, 영적안녕, 자아개념 및 자아존중감과의 관계

강은실 ( Kang Eun Sil ) 한국정신간호학회 2003 정신간호학회지 Vol.12 No.3

N/A This study was carried out to identify the relationships of Purpose in lift, Self-esteem and Spiritual well-being of adolescence. Design of the research was correlational study. Objects of the study were 215 high school students in M city of Korea. Data was collected from 7th Nov. 1999 to 12th April, 1999 using by structured questionaire. Inventories of the study were PIL(Purpose in Life) scale developed by Crumbaugh & Maholick(1969), Self-concept scale by Lee & Won(1995), Rosenberg`s self-esteem scale translated by Choi(1972), spiritual well-being scale developed by Paloutzian & Ellison, translated by Choi(1990). Collected data were analyzed by frequency, percentage, mean, standard deviation, t-test, ANOVA, Pearson`s correlation using SPSS?PC 10.0 program. The results were as follow : 1. Mean value of purpose in life(87.14), Spiritual well-being(41.31), Self-concept(107.12), Self-esteem(37.91) of adolescence were low. 2. Relationships of the Purpose in life, Spiritual well-being Self-concept and Self-esteem of adolescence. Purpose in life of adolescence are positive relationships with Spiritual well-being(r=.355, P= .000), Self-concept(r=.488, P= .000) and Self-esteem of adolescence(r=.499, P= .000). Self-concept of adolescence are positive relationships with Purpose in life(r=.488, .000), Spiritual well-being(r=.141, P= .041) and Self-esteem of adolescence(r=.753, P= .000). Self-esteem of adolescence are positive relationships with Purpose in life(r=.459, P= .000), Self-concept of adolescence (r=.753, P= .000). Spiritual well-being of adolescence are positive relationships with Purpose in lift(r=.355, P=.000), Self-concept of adolescence(r=.141, P= .041). In conclusion. Purpose in life of adolescence are positive relationships with Spiritual well-being Self-concept and Self-esteem of adolescence. Therefore, development of program to increase Purpose in life of the adolescence will be necessary.

교회청소년과 일반청소년의 삶의 목적,영적안녕, 자아개념 및 자아 존중감 비교

강은실(Kang,Eun Sil),이영은(Lee,Young Eun),조향숙(Cho,Hyang Suk),최은주(Choi,Eun Ju) 고신대학교 전인간호과학연구소 2002 전인간호과학학술지 Vol.1 No.-

T his study was carried out to compare the Purpose in life, Self-concept, Self-esteem and Spiritual well-being between in-church adolescence and out-church adolescence. Design of this study was descriptive comparative study. Object of the study were 215 adolescences of high school students in P,M city of Korea. Data was collected from 7th Nov. to 12th A pril using structured questionaire. Tools of this study were PIL(Purpose in Life) developed by Crumbaugh, Maholick 1969),scale for self- concept by Lee & Won (1995),Rosenberg s self- esteem scale translated by Choi(1972), scale for spiritual well-being of Paloutzian & Ellison translated by Choi(1990) Collected data were analyzed by frequency, percentage, chi-square test, mean, standard deviation, independent t-test, ANOVA with SPSS/PC 10.0 program. The results were as follow 1. Purpose in life, Spiritual well-being of in-church adolescence were statistically higher than them of out-church adolescence(t=-2.759,P=.006,t=-11.082,P=.000). 2. General characteristics statistically related to the Purpose in life, Self-concept, Self-esteem and Spiritual well-being between in-church adolescence and out-church adolescence 1) General characteristics of in- church adolescence statistically related to the Purpose in life between in- church adolescence and out- church adolescence The general characteristics statistically related to the Purpose in life are the influence of the religion to own s life(F=5.175, p= .002),the supervision of the God to my day life(F=5.513, p= .000),the degree of help of the religious life or religion(F=3.055, p= .019),the degree of reading of religious books (F=7.623, p=.000),the need of religious life(F=7.872.,p=.001), the degree of meditation or contemplation prayer(F=4.635,p= .002),the degree of attendance at a religious service(F=3.202, p= .026). The general characteristics of out church adolescence statistically relate to the Purpose in life are the level of life(F=2.544, p= .035),the motivation of entrance into an university(F=2.744, p=.048), the religion of parents(F=3.049, p=.014), the family atmosphere(F=3.650, p=.016), the influence of the religion to own s life(F=8.064, p= .001), the supervision of the God to my day life(F=3.914, p= .006),the degree of help of the religious life or religion(F=4.142, p=.004), the degree of reading of religious books(F=7.144, p= .000), the degree of attendance at a religious service(F=5.577,p= .001). 2) General characteristics statistically relate to Spiritual well-being of in church and out-church adolescence The general characteristics statistically related to Spiritual well-being are meaning of religion or God to me(F=4.900,p= .000),the motivation of entrance into an university(F=2.886, p= .038),the influence of religion to own s life (F=20.598, p= .000),the supervision of God to my day life(F= 14.702, p= .000),the degree of reading of religious books (F=3.856, p= .005),the need of religious life(F=19.201,p= .000),the degree of meditation or contemplation prayer (F=9.723, p=.000), the degree of attendance at a religious service(F=8.779, p= .000). The general characteristics statistically related to Spiritual well-being of out-church adolescence are the religion of parents(F=2.638, p= .030),the influence of religion to one s life(F=19.931,p= .000),the supervision of God to my day life(F=22.927, p= .000),the degree of helf of religious life or religion(F= 12.649,p=.000), the degree of reading of religious books (F=7.057, p= .000),the need of religious life(F=14.444,p= .000),the degree of attendance at a religious service(F=7.755, p= .000),the counsel subject of one s personal affairs(F=2.840, p= .030).3) General characteristics statistically related to Self-concept of in- church and out-church adolescence.The general characteristics statistically related to Self-concept of in- church adolescence are the family atmosphere (F=7.296, p= .000), the motivation of entrance into an uni

일부 지역 청소년의 인터넷 및 휴대폰 중독 실태

강은실(Eun-Sil Kang),손조욱(Jo-Wook Son),박소연(So-Yeon Park),이미선(Mi-Sun Lee),백현숙(Hyun-Sook Baek) 고신대학교 전인간호과학연구소 2008 전인간호과학학술지 Vol.3 No.-

Purpose: This study investigated the degree and frequency of Internet and cellular phone addiction of Korean adolescents to provide basic data for prevention and intervention. Methods; The subjects of the research were 336 students selected out of 1 middle school and 2 high schools of P city in Korea. The data was collected by the use of a structured questionnaire. A survey tool was used that was developed in the Center for On-line Addiction (1996) to investigate Internet addiction by Young (1996) and Jang s (2002) Cellular Phone Addiction Test. The data was analyzed with the SPSS 12.0/PC program. Results: The percentage of the adolescents who had Internet addiction tendency was 30.1% and cellular phone addiction tendency was 26.2%. The percentage of the reason as to why they used the Internet was for fun in 55.1% and the Internet using experience was over 5 years in 72.9%. The percentage of those who used the Internet daily was 33.8%. The percentage of those who used cellular phones for over 3 years was 31.3% and the reason why they bought cellular phones was because their friends had cellular phones and this was the case in 32.1%. The percentage of those who had sent text messages in class were 63.7%. The degree of cellular phone addiction was significantly high in female, middle school students, related Conclusions: Related variables in Internet and cellular phone addiction should be done involving a correlative study and all kinds of different schools need to be investigated (such as vocational high schools). Therefore the results of this study can be used as a basic data to develop a prevention program for Internet and cellular phone addiction.