http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
A Case of Myocardial Abscess Mimicking Acute Myocardial Infarction
강원유,김성수,윤현주,김주한,정명호,조정관,강정채,박종춘,김현국,안영근 한국심초음파학회 2009 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.17 No.2
Myocardial abscess, a rare and life-threatening disease, occurs as a complication of infective endocarditis, acute myocardial infarction, or other infections in the setting of debilitating condition. We report a case of myocardial abscess mimicking acute myocardial infarction (AMI), not a following consequence of AMI. We can diagnose the disease with the aid of transthoracic echocardiography and cardiac computed tomography.
베트남 참전 고엽제 환자에서 심혈관 질환의 발생이 더 흔한가?
강원유 ( Won Yu Kang ),김한균 ( Han Gyun Kim ),정명호 ( Myung Ho Jeong ),조상철 ( Sang Cheol Cho ),정안덕 ( An Doc Jung ),조용찬 ( Yong Chan Cho ),기영화 ( Young Hwa Ki ),이봉규 ( Bong Gyu Lee ),황선호 ( Sun Ho Hwang ),김원 ( Weo 대한내과학회 2007 대한내과학회지 Vol.73 No.3
목적: 베트남 전쟁 당시 사용했던 고엽제(Agent orange)의 구성 물질 중 하나로 dioxin으로 잘 알려진 TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin)는 소량으로도 맹독성이 있으며 체내에 축적됨으로서 인체에 여러 영향을 미치는 것으로 보고되고 있다. 하지만 심혈관 질환의 발생과 고엽제의 인과관계는 불분명한 상태이다. 이에 저자들은 베트남 전쟁에 파병되었던 환자들을 대상으로 하여 고엽제가 심혈관질환의 발병에 어떠한 영향을 미치는지와 고엽제에 폭로되었던 사람들의 심혈관 질환의 특징을 알아보고자 하였다. 방법: 2004년 4월부터 2005년 6월까지 광주보훈병원에서 관상동맥 조영술을 시행 받은 115명을 대상으로 하였다. 57명의 TCDD에 노출된 군과 58명의 노출되지 않은 군으로 분류하여 임상소견, 검사실 소견 및 관상동맥 조영술 소견 등을 후향적으로 분석하였다. 결과: 임상소견, 검사실 소견, 좌심실 구혈율 등에 양군 간에 차이는 보이지 않았다. I군에서 당뇨병(Group I: 43.9%, Group II: 25.0%, p=0.035)과 고지혈증(I군: 47.4%, II군: 27.6%, p=0.028)이 유의하게 높았다. 관상동맥의 병변은 I군 45명(78.9%), II군에서 33명(56.9%)으로 I군에서 유의하게 많았으며(p=0.011), 스텐트를 사용한 환자 또한 I군에서 26명(26/33), II군에서 15명(15/24)으로 I군에서 유의하게 많았다(p=0.027). 그러나 병변혈관의 수나 목표혈관의 완전폐쇄 유무 및 ACC/AHA classification과 TIMI flow 등은 양 군 사이에 유의한 차이는 보이지 않았다. 결론: 고엽제에 노출된 환자에서 관상동맥 질환의 원인 인자로 알려진 당뇨병과 고지혈증이 더 많이 발생하였고 관상동맥 병변의 발생율도 높았다. Background: TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin), a material of agent orange, was reported as a deadly poison in spite of its presence at extremely small doses. It has been reported that TCDD can cause various kinds of cancers and harmful effects on humans. However, a correlation between exposure to TCDD and cardiovascular disease is not yet known. Thus, we intended to examine the correlation between TCDD exposure and cardiovascular disease through an analysis of coronary angiograms in veterans of the Vietnam War. Methods: A consecutive 115 patients undergoing coronary angiograms between April 2004 and June 2005 at Gwangju Veterans Hospital were analyzed. The patients were divided into two groups: 57 patients exposed to TCDD (Group I, average age 59.2±4.2 years) and 58 patients that were not exposed to TCDD (Group II, Average age 60.1±5.6 years). The clinical and coronary angiographic findings were evaluated. Results: Baseline clinical characteristics, inflammatory markers and echocardiographic parameters were not different between patients in the two groups. The incidence of diabetes (43.9% vs. 25.0%, p=0.035) and hyperlipidemia (47.4% vs. 27.6%, p=0.028) were higher in group I patients than group II patients. Significant coronary artery stenosis was more common in group I (45 cases, 78.9%) thanin group II (33 cases, 56.9%) (p=0.011). Conclusions: There was a higher incidence of diabetes, hyperlipidemia, and significant coronary artery stenosis in patients that underwent a diagnostic coronary angiogram that were previously exposed to TCDD.(Korean J Med 73:299-306, 2007)
The Impact of Chronic Cigarette Smoking on Arterial Stiffness in Korea
김종범,강원유,김승주,홍명주,박찬영,노형민,홍경희,황선호,김완 대한노인병학회 2011 Annals of geriatric medicine and research Vol.15 No.1
Background: Cigarette smoking is an important modifiable cardiovascular risk factor, which is known to acutely increase arterial stiffness. But the chronic effects of smoking on arterial stiffness are still controvertial. We studied the effects of chronic cigarette smoking on arterial stiffness in Korean subjects. Methods: Our subjects included those >18 years of age (n=2685, 991 females) who had undergone a pulse wave velocity from July 2004 to June 2008. They were classified into two groups, smokers (n=641) and non-smokers (n=2044). In addition to the pulse wave velocity (PWV), we reviewed the highly sensitive C-reactive protein levels in a random manner when it was available. Results: Males were predominant in the smokers group. Smokers had significantly higher heart-femoral PWVs than nonsmokers(1083.6±264.1 cm/sec vs. 1041.3±257.3 cm/sec; p<0.001). There was no linear relationship between smoking duration and PWV (r= -0.225, p=0.506) even after adjusting for age, sex, and body mass index. Furthermore, there was no difference in the ankle-brachial index between the two groups. On the multivariate regression analysis, age, male gender, hypertension, and diabetes were independent predictors of increased arterial stiffness. Conclusion: In this study, chronic cigarette smoking increased central arterial stiffness in Korean subjects.
임철환,강원유,김연화,안혜미,황선호,김원,김완,홍영준,안영근,정명호,강정채 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.1
Background and Objectives: Drug-eluting stents has been used to treat in patients with coronary artery diseases and shown to reduce rate of restenosis. We compared the efficacy and safety of the sirolimus-eluting stent (SES) versus the zotarolimus-eluting stent (ZES) versus the paclitaxel-eluting stent (PES) in patients with acute coronary syndromes. Methods: A postspective, multicenter, randomized trial was conducted to evaluate the safety and efficacy of SES (n=2357), ZES (n=283) and PES (n=1771) in 4423 patients undergoing primary percutaneous revascularization. The primary end point was composite of major adverse cardiac events at 6 months and 12 months: all-cause death, cardiac death, myocardial infarction and clinically driven target vessel revascularization. Results: At 6 months, the primary endpoint had occurred in a lower patients treated with SES than ZES (8.7% vs. 17%, HR 0.46, 95% CI 0.33-0.65, p<0.001), SES than PES (8.7% vs. 11.3%, HR 0.74, 95% CI 0.60-0.91, p=0.006) and higher patients treated with ZES than PES (17% vs. 11.3%, HR 1.61, 95% CI 1.14-2.25, p=0.005). At 12 months follow-up, this difference was similar results. SES vs. ZES (11.9% vs. 21.4%, HR 0.49, 95% CI 0.36-0.67, p<0.001), SES vs. PES (11.9% vs. 14.8%, HR 0.78, 95% CI 0.65-0.93, p=0.007), ZES vs. PES (21.4% vs. 14.8%, HR 1.57, 95% CI 1.15-2.13, p=0.004). All cause-motality at 12 months was SES vs. ZES (2.7% vs. 6.5%, HR 0.40, 95% CI 0.23-0.68, p<0.001), SES vs. PES (6.5% vs. 3.8%, HR 1.75, 95% CI 1.03-2.97, p=0.03), ZES vs. PES (2.7% vs. 3.8%, HR 0.71, 95% CI 0.50-1.00, p=0.53). Conclusion: Compared with ZES and PES, SES had superior clinical outcome.