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      • 평균 수명 이상의 고령 위암 환자에서의 D2 림프절 절제술의 안정성

        강우성,정오,정미란,김호군,류성엽,박영규,김동의,김영진,Kang, Woo Sung,Cheong, Oh,Jeong, Mi Ran,Kim, Ho Goon,Ryu, Sung Yeop,Park, Yeong Kyu,Kim, Dong Yi,Kim, Young Jin 대한위암학회 2008 대한위암학회지 Vol.8 No.2

        Purpose: The aim of this study was to evaluate the safety and feasibility of D2 lymphadenectomy in elderly patients with gastric cancerby comparing the surgical outcomes and postoperative courses between an elderly group and a control group undergoing the same procedure. Materials and Methods: Clinical information was reviewed for 1251 patients with gastric cancer who underwent gastrectomy between May 2004 and May 2007. Patients were classified into the following two groups: an elderly group (older than the average life span in Korea) and a control group (younger than the elderly group). Clinicopathologic features and postoperative courses after D2 lymphadenectomy were reviewed and compared between the two groups. Results: There were a total of 120 (9%) elderly group patients among all those reviewed, and 86 (72.2%) of them underwent D2 lymphadenectomy. There was 27.5% postoperative morbidity in the elderly group, which was significantly different from thecontrol group (12.8%, p=0.003). However, on multivariate analysis, ASA score and combined resection were independent predictive factors of postoperative complications, while age was not predictive. Conclusion: Older age is not a predictive factor of postoperative complications in itself, and D2 lymphadenectomy can be safely performed in elderly patients with gastric cancer, provided they have good ASA scores and do not undergo accompanying combined resection.

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        ns-2 기반 WAVE 멀티채널 시뮬레이션 프로그램 작성 및 검증

        강우성,정진욱,진교홍,Kang, Woo-Sung,Jung, Jin-Uk,Jin, Kyo-Hong 한국정보통신학회 2011 한국정보통신학회논문지 Vol.15 No.7

        A typical standard of vehicular ad hoc networks, WAVE which consists of IEEE 1609.x Family standards and IEEE 802.11p standard, includes the multi-channel coordination and channel synchronization function to provide safety services or public services during a car is driven. Generally, the performance of data communication and networking technologies is evaluated by using simulation tools, such as ns-2, OPNET, OPNET++, etc. However, these tools doesn't provide the operations of WAVE protocol. Therefore, in this paper, we implement and verify WAVE simulation program based on ns-2. WAVE는 IEEE 1609.x 패밀리 표준들과 IEEE 802.11p 표준으로 구성된 차량 에드혹 네트워크의 대표적인 표준으로 차량 운행시 안전 서비스, 편의 서비스 등을 제공하기 위해 멀티채널 코디네이션과 채널 동기화와 같은 동작들을 포함하고 있다. 데이터 통신 및 네트워킹 기술들은 일반적으로 ns-2, OPNET, 그리고 OPNET++와 같은 시뮬레이터들을 사용하여 그 성능이 평가되지만, 현재까지 이러한 툴들은 WAVE 프로토콜의 동작들을 제공하고 있지 않다. 따라서 본 논문에서는 ns-2를 기반으로 하여 WAVE 멀티채널 시뮬레이션 프로그램을 작성하고 검증하였다.

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        인진청간탕(茵蔯淸肝湯)이 HepG2 cell의 $TNF-\alpha$ 신호전달계에 미치는 영향(影響)

        강우성,김영철,이장훈,우홍정,Kang Woo-Sung,Kim Young-Chul,Lee Jang-Hoon,Woo Hong-Jung 대한한방내과학회 2004 대한한방내과학회지 Vol.25 No.1

        Objectives : The main purpose of this study is to evaluate the effect of Injinchunggan-tang on $TNF-{\alpha}$ signal transmission system. Materials and Methods : We analyzed the following with quantitative RT-PCR method; the effect of Injinchunggan-tang on secretion of $TNF-\alpha$ mRNA/protein and stability, the effect on gene revelation that consists of signal transmission system (TRAIL, NIK, A20, TRADD, RAIDD, RIP TNFR-I, TNFR-II, TRAF1, TRAF2, FADD), the one on activation of p38, Erk1/2 MAPK and the rate of nuclear $NF-{\kappa}B/cytosolic\;NF-{\kappa}B$ in HepG2 cell. We also analyzed the inhibitory effect of Injinchunggan-tang on the apoptosis of HepG2 cell that $TNF-{\alpha}$ induces and the $NF-{\kappa}B$ restraint effected by transfection of $I{\kappa}B{\Delta}N$ through tryphan blue exclusion assay. Results : Injinchunggan-tang prohibits revelation of $TNF-{\alpha}$ mRNA in HepG2 cell and the creation of protein. However, it has no effect on the stability of $TNF-{\alpha}$ mRNA. While it did not have any effect on the generation of TRAIL, NIK, A20, TRADD, RAIDD and RIP genes, Injinchunggan-tang reduces the revelation of TNFR-I, TNFR-II, TRAF1, TRAF2 and FADD genes. It has been confirmed that Injinchunggan-tang restraints the revelation of $TNF-{\alpha}$ mRNA that is promoted by ethanol, acetaldehyde, lipopolysaccharide, in proportion to the treatment density and time. It activated $NF-{\kappa}B$ of HepG2 cell and promoted activation of $NF-{\kappa}B$ that is occurred by $TNF-{\alpha}$. It has been observed that the restraint effect against the $TNF-{\alpha}$ inducing apoptosis is lost when it is intercepted the function of $NF-{\kappa}B$ in HepG2 cell. Conclusion: It has been confirmed that Injinchunggan-tang has restraining effect against the revelation of $TNF-{\alpha}$ and mRNA that is constituent element of TNF-a signal transmission system. It also has been revealed that it restraints the activation of p38, Erk1/2 by $TNF-{\alpha}$. Through this prohibiting effect, it is inferred that it restraints signal transmission among various cells that are related to inflammation reaction. Meanwhile, Injinchunggan-tang protects liver cell from apoptosis that is caused by $TNF-{\alpha}$, by maintaining the activating function for $NF-{\kappa}B$.

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      • KCI등재

        파레르곤의 논리: 데리다와 미술

        강우성 ( Woo Sung Kang ) 영미문학연구회 2008 영미문학연구 Vol.14 No.-

        In Truth in Painting and Memoirs of the Blind, French philosopher Jacques Derrida attempts to elaborate on the role and the significance of painting in his life-long endeavors of deconstructing Western metaphysics. Revisiting time-old philosophical themes of presentation and representation in the arts of the visual and critically reassessing philosophical assumptions of the truth in Kant, Hegel, and Heidegger, Derrida points out that arts in general, and painting in particular, have been paradoxically based on the logic of parergon: what was considered the outside or the frame of the painting proper, namely, cartouche. Parergon in painting, which is itself a kind of fragment, illustrates the lack extant inside the work (ergon) but at the same time makes it possible for the work to be itself. Such an operation of parergon in painting destroys the priority of the letter over the drawing. The truth in paining does no longer depend upon the discursive representation concerning what a painting truly is about. Kant`s Third Critique and the Heidegger-Schapiro debate on Van Gogh`s paintings of boots are critically examined as the example of metaphysical desire to incorporate and restitute the truth of the work within the boundary of human subject. Citing Valerio Adami`s drawings after Glas and Gerard Titus-Carmel`s series of coffin drawings of primitive tribe, Derrida also deconstructs the philosophical logic of dividing what is proper and what is not in any work of art. Derrida`s reconsideration of the philosophical idea of truth and pictorial representation extends to the deconstruction of the priority of the visual to the invisible. As Derrida famously says, eyes are not made to see but to weep. Tears are like the parergon of the eyes. They show that there is the lack in human faculty of seeing. Self-portrait, which originates from the blind spot in the canvas, is the case in point of such a logic of parergon. Blindness caused by tears is constitutional in any process of painting the truth because parergon, as the signifier of the lack, demonstrates the abyss of human faculty of seeing and the origin of painting from such lack.

      • KCI등재
      • KCI등재

        실패한 이주민의 꿈: 끄레브꾀르의 『미국 농부의 편지』

        강우성 ( Woo Sung Kang ) 영미문학연구회 2009 영미문학연구 Vol.16 No.-

        This paper revisits Cre` vecoeur`s Letters from an American Farmer in terms of its narrative hybridity and the concomitant failure of establishing the figure of American farmer as an archetypal American. Up until now, most of the critics did not pay full-fledged attention to the narrative complexity of Cre` vecoeur`s Letters, predominantly capitalizing on the cultural as well as political significance of the third letter, What is American?; they often let slide the ideological implication of the freeholding farmer, let alone the strategic placement of the so-called Nantucket Letters in the middle of narrative structure. Agrarian pastoral of the Pennsylvanian farm precariously extends its figurative power over the ample narrative descriptions of the oceanic community in Nantucket via the critical lenses of the contemplative narrator-hero, ultimately resulting in the narrative debacle that could not curb the stark reality of slavery in Charles Town and the bewilderment over the unexpected thrust of political choice in front of impending war with English monarchy. Contemplative farmer`s benevolent governance as a monarcho-anarchist over the independent, market-free farm yard falls far short of being translated into the dominant principle of polity of the whole colony. The attempt to set up an ideal of freeholding farmer as an archetypal American manhood turns out a meaningful failure: he becomes neither a successful immigrant-turn-American nor a republican citizen of democracy. It is, therefore, both inevitable and natural for the farmer-contemplator to resort to the natural law of self-preservation and regress into the non-political residency in the frontier Indian community. As D. H. Lawrence puts it, Cre` vecoeur`s backward political gesture records the failure of founding a mythic American manhood in the complicating realities of the 18th century American culture. In its narrative hybridity and the creation of contemplative narrator, Cre` vecoeur`s emotional description of the farmer`s wish-fulfillment to remain an independent man of self-preservation anticipates the literary flowering of the distinctive American prose styles in the era of the so-called American Renaissance.

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