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강대호 신학과사상학회 2006 가톨릭 신학과 사상 Vol.- No.57
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강대호,신진웅,오준환,최성권,최윤경,이수선,김도강 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.1
Gastrointestinal stromal tumor (GIST) of ileum is a rare tumor of gastrointestial tract that arise from primitive mesenchymal cells. GIST occur predominantly in persons over 40 years of age with an equal sex incidence. GIST expresses a heterogenous clinical course and the most important prognostic factors are tumor size, site, degree of mitotic activity, tumor necrosis. We report a case of GIST of ileum, which was misdiagnosed as extrauterine leiomyoma preoperatively.
자연 유산의 영양배엽에서 LH / CG 수용체 , α 및 β - hCG 의 발현
강대호,신진웅,변태섭,김도강,오준환,이수선,이방현,최성권,류기성 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.10
Objective : To investigate the mechanisms involved in the mRNA expressions of hCG, LH/CG receptor and in hormone secretion in the trophoblast of normal and abnormal early pregnancy. Methods : hCG, free β-hCG, and progesterone concentrations were measured in serum and the mRNA expressions of α,β-hCG and LH/CG receptor were measured in the placental trophoblast of 22 spontaneous abortion patients (spontaneous abortion group), 20 normal pregnancy women (normal pregnancy group) and 6 hydatidiform mole patients (hydatidiform mole group). Results : 1. Mean values of serum hCG and free β-hCG concentrations were the lowest in spontaneous abortion group (46343.63±40404.18 mIU/ml, p$lt;0.001; 31.34±61.57 mIU/ml, p$lt;0.01 respectively) among the three groups. Mean progesterone concentration was the lowest in spontaneous abortion group (11.84±7.60 ng/ml, p$lt;0.01), too. 2. The expression levels of α,β-hCG were the highest in spontaneous abortion group (4.64±5.47, p=0.015; 4.57±4.42 p=0.002 respectively). The expression levels of LH/CG receptor were not different statistically among the three groups and they were high at the 5th week of gestation, reaching nadir at the 10th week of gestation when the concentrations of serum hCG showed peak values in normal pregnancy group. 3. The correlations between serum hCG and progesterone concentrations were positive in both spontaneous abortion (r=0.827, p$lt;0.001) and normal pregnancy (r=0.438, p=0.054) group. Though they were not significant statistically, the correlations between progesterone concentrations and the levels of α,β-hCG expressions were negative in both spontaneous abortion (r=-0.237, p=0.289; r=-0.211, p=0.347) and normal pregnancy (r=-0.270, p=0.250; r=-0.235, p=0.318) group. In hydatidiform mole group, the correlation between progesterone concentrations and the levels of β-hCG expression was positive (r=0.968, p=0.002). Conclusion : Our results suggest that the mechanisms involved in the secretion of hCG, progesterone and the expression of α,β-hCG, LH/CG receptor be normal in spontaneous abortion as in normal pregnancy and in the both groups, hCG stimulate the secretion of progesterone by autocrine function and control the secretion of itself, through the suppression of the expressions of α,β-hCG and LH/CG receptors. So the cause of spontaneous abortion in early pregnancy may be not placental dysfunction but the defect of embryo itself with poor placental growth.
강대호 전주대학교 공학연구소 1997 전주대학교 공학기술종합연구소 학술논문집 Vol.3 No.3
According to the building regulation in Korea, war-time shelters shall be provided in the underground spaces in all apartment houses. However, at present in peace-time, the underground spaces have trends to be used as storage room or for other uneffective purposes with low-quality indoor invironment. Over 30 cases of present use of the underground spaces have been surveyed and analyzed. In most of the cases, the underground spaces are used for stocks of storage illegallly, only few used for small community spaces actively. In the study, Some problems of the present uses are duscussed and some alternatives such as sunken garden for the cummunity common spaces are suggested for both war-time shelter and peace-time shelter, with the view of acitve and effective spaces utilization.