放送衛星의 Antenna Beam幅角 計算의 한 方法

강기연 대한전자공학회 1977 電子工學會雜誌 Vol.4 No.1

행인(杏仁) 분획물이 Th2 cytokine 발현과 NC/Nga mouse의 아토피 피부염에 미치는 영향

강기연,한재경,김윤희,Kang, Ki Yeon,Han, Jae Kyung,Kim, Yun Hee 대한한방소아과학회 2016 대한한방소아과학회지 Vol.30 No.4

Objectives PRAL (Prunus armeniaca Linne Var) has been known to suppress allergic reaction. However, the cellular target and its mechanism of action were unclear. This study was designed to investigate the effect of PRAL on RBL-2H3 mast cell, which is PMA-Ionomycin-induced activated in vitro and the effect of PRAL on the MNC/Nga mice that are DNCB-induced activated in vivo. Methods In this study, IL-4, IL-13 production were examined by ELISA analysis; IL-4, IL-13, IL-31, IL-31Ra, $TNF-{\alpha}$ and GM-CSF mRNA expression were examined by Real-time PCR; manifestations of AP-1 and MAPKs transcription factors were examined by western blotting in vitro. Then skin rashes have been evaluated and verified the distribution of mast cells by H&E and toluidine blue. Also, WBC, eosinophil and neutrophil, IgE level in serum, $IFN-{\gamma}$, IL-4, IL-5 in the splenocyte culture supernatant, the absolute cell numbers of $CD4^+$, $CD8^+$, $Gr-1^+CD11b^+$, $B220^+CD23^+$, $CD3^+CD69^+$ in the Axillary Lymph Node (ALN), PBMCs and dorsal skin and IL-5, IL-13, IL-31, IL-31Ra in the dorsal skin by Real-time PCR were all evaluated from the NC/BNga mice. Results As a result of this study, the mRNA expression of IL-4, IL-13, IL-31, IL-31Ra and $TNF-{\alpha}$ and IL-4, IL-13 production, shown in ELISA analysis, were suppressed by PRAL. Results from the western blot analysis showed decrease on the expression of mast-cell-specific transcription factors, including AP-1 and p-JNK, p-ERK. Histological examination showed that infiltration levels of immune cells in the skin of the AD-induced NC/Nga mice were improved by PRAL orally adminstration. Orally- administered PRAL group also showred decreased level of IgE in the serum. This group has shown decreased the level of IL-4, IL-5, but shown elevated $IFN-{\gamma}$ level in the splenocyte culture supernatant. The same group also has shown decreased cell numbers of $CD4^+$, $CD8^+$, $CD3^+CD69^+$ in the ALN, and $CD4^+$, $Gr-1^+CD11b^+$ in the dorsal skin. PRAL oral adminstration increased cell numbers of $CD4^+$, but decreased cell numbers of $CD8^+$, $Gr-1^+CD11b^+$, $B220^+CD23^+$ in the PBMCs. Conclusions Obtained results suggest that PRAL can regulate molecular mediators and immune cells that are functionally associated with atopic dermatitis (AD) induced in the NC/Nga mice. This may play an important role in recovering AD symptoms and suppressing pruritus.

부모의 신장과 TW3법에 의한 예측 신장 (AHP TW3)의 상관성 연구

강기연,한재경,김윤희,Kang, Ki-Yeon,Han, Jae-Kyung,Kim, Yun-Hee 대한한방소아과학회 2012 대한한방소아과학회지 Vol.26 No.3

Objectives The purpose of this study is to find out the relationship between parents' heights and predicted height of the children who had been treated in the growth clinic of oriental medical hospital. Methods The study was conducted with 253 children who visited Oriental Medical Hospital from July 2010 to June 2012. They were analyzed by reviewing the children's chart and correlation analysis to find out the relationship between the two heights. Results In distribution of the sex and the age, sex were similar, but boys who came to the clinic were averagely younger than the girls. In predicting adult height by TW3 method and mean parent's height, correlation in the girls was higher than the boys, especially the girls after their first menstruation. Parents' heights were related to both the boys and the girls, but mother's height was more closely related. Predicted heights of the boys before secondary sex characteristics were correlated with the child's height, but rather correlated with parent's both heights after secondary sexual character and found to be more relevant to father's height. The girls' predicted heights before their menstruation were not correlated with father's height, but with mother's. Their heights after their first periods were correlated with parents' both heights, but more correlated with father's height. Conclusions This study helps set proper periods and goals of growth treatment based on the correlation between parents' height and predicted adult height according to TW3 method.

TV 음성다중방송방식 개요

강기연 대한전자공학회 1980 電子工學會雜誌 Vol.7 No.4

GHOST 對策用 可變指向性 안테나의 計算設計

강기연 대한전자공학회 1979 電子工學會雜誌 Vol.6 No.1

단파용 Curtain 안테나의 지향성

강기연 대한전자공학회 1976 電子工學會雜誌 Vol.3 No.2

MC/9 비만세포에서 행인(杏仁) 추출물의 Th2 cytokine 발현 억제 효과 및 신호전달 기전 연구

강기연,한재경,김윤희,Kang, Ki Yeon,Han, Jae Kyung,Kim, Yun Hee 대한한방소아과학회 2014 대한한방소아과학회지 Vol.28 No.2

Objectives PRAL (Prunus armniaca Linne Var) is a herbal formula in Oriental Medicine, known for its anti-inflammatory and anti-allergenic properties. However, its mechanism of action and the cellular targets have not yet been found enough. The purpose of this study is to investigate the effects of PRAL on Th2 cytokines expression in MC/9 mast cells. Methods The effect of PRAL was analyzed by ELISA, Real-time PCR, Western blot in MC/9 mast cells. mRNA levels of GM-CSF, IL-4, IL-5, IL-6, IL-13, TNF-${\alpha}$ were analyzed with Real-time PCR. Levels of IL-13, MIP-$1{\alpha}$ were measured using enzyme-linked immunosorbent assays (ELISA). NFAT, AP-1 and NF-${\kappa}B$ p65 were examined by Western blot analysis. Results PRAL inhibited GM-CSF, IL-4, IL-5, IL-6, IL-13, TNF-${\alpha}$ mRNA expression in a dose dependent manner. GM-CSF, IL-4, IL-5 mRNA expression were inhibited significantly in comparison to DNP-IgE control group at concentration of 100 ${\mu}g/ml$ and IL-6, IL-13, TNF-${\alpha}$ mRNA expression were inhibited at concentration of 50 ${\mu}g/ml$, 100 ${\mu}g/ml$. PRAL also inhibited the IL-13, MIP-$1{\alpha}$ production significantly in comparison to DNP-IgE control group in a dose dependent manner. IL-13 production was inhibited at a concentration of 200 ${\mu}g/ml$, 400 ${\mu}g/ml$ and MIP-$1{\alpha}$ was inhibited at a concentration of 100 ${\mu}g/ml$, 200 ${\mu}g/ml$, 400 ${\mu}g/ml$. Western blot analysis of transcription factors involving Th2 cytokines expression revealed prominent decrease of the mast cell specific transcription factors including NFAT-1, c-Jun as well as NF-${\kappa}B$ p65 but not NFAT-2 and c-Fos. Conclusion These results indicate that PRAL has the effect of suppressing Th2 cytokines production in the MC/9 mast cells. These data represent that PRAL potentiates therapeutic activities to the allergic disease by regulating Th2 cytokines in the MC/9 mast cells.

멕시코올림픽 TV중계회선

강기연 대한전자공학회 1968 전자공학회지 Vol.5 No.3

난연성 FREP에 의한 철근콘크리트 보의 전단보강 성능평가

강기연,최기선,한상환,유영찬 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

The purpose of this study is to evaluate the shear strengthening effects of the iFREP(incombustible Fiber Reinforced Epoxy Panel) to the reinforced concrete members and to provide the basic design recommendation for shear strengthening. The main variable were the thickness of iFREP, the amount of stirrup and the type of strengthening. Thirteen specimens were tested under static monotonic loading. From the test results, it was shown that the failure mode of RC beams which are strengthened by iFREP was governed by the delamination of iFREP. The shear capacity of beams strengthened by iFREP can be determined as the summation of the shear strengths provided by concrete, stirrup, and iFREP The shear strength by iFREP should be calculated based on the effective strain of iFREP. Also, the shear strengthening effects of specimen with two-side bonded iFREP is similar to those of specimen with three-side bonded iFREP (U-TYPE).

한방병원에 내원한 소아청소년기 말초성 안면마비 환자 284례를 통한 임상적 고찰

강기연,이혜림,한재경,김윤희,Kang, Ki Yeon,Lee, Hye Lim,Han, Jae Kyung,Kim, Yun Hee 대한한방소아과학회 2014 대한한방소아과학회지 Vol.28 No.4

Objectives The purpose of this study is to investigate the clinical characteristics in children and adolescents with peripheral facial palsy that was treated with Korean medicine. Methods The study was conducted based on 284 cases that consisted of 261 children (less than 19 years old) who visited the hospital of Korean medicine from August 2010 to August 2014. Then, this study was analyzed by reviewing the patients' charts. Results The incidence of facial palsy in pediatric patients was more common in boys than in girls and the mean age was 11.2 years. The prevalence of facial palsy was more common in winter and most were diagnosed with Bell's palsy. Recurrence was identified in 12.6% of the patients. The average age of the first attack was 9.5 years. It took about 3.2 years for recurrence to occur from the first onset. It took about 5 days to visit the hospital of Korean medicine from the onset. 81% of the patients came within 1 week from the onset. 50.7% of the cases did not receive any treatment before and 49.3% were previously treated at other hospitals. More than half of the patients (65.1%) received Korean medicine first. 54.6% of the patients were hospitalized and 45.4% received outpatient treatments in the hospital of Korean medicine. Outpatient treatments were administered about 11.5 times while hospitalized patients were treated for an average of 16.6 days. In general, hospitalized patients were treated more often than the outpatient group. An overall average duration of treatment was 70.6 days from the onset of facial palsy until the last day of treatment, and 53.0 days from the first day of treatment until the last day of treatment. 41.5% of the cases were treated only with Korean medicine and 49.0% were treated with a combination of Korean and Western medicine. The types of Korean medicine treatment used for facial palsy in descending order of frequency were acupuncture, Infra red, herbal medicine, SSP therapy, electro-acupuncture, carbone, hot pack, cupping, and moxibustion. The treatments that were most frequently used from Western medicines were steroid as monotherapy (61.7%) and a combination of steroids and antiviral therapy (37.6%). Conclusions This result showed that the risk of facial palsy recurrence among children is relatively high and that facial palsy requires a long-term treatment. It's helpful to explain about prognosis, treatment duration, and recurrence potential in children. Facial palsy in children is treated in various ways but more studies about the therapeutic effects of Korean medicine, Western medicine, and combination of Korean-Western medicine in children are needed.