LabVIEW를 기반으로 한 단일 영상에서의 안개 제거

황보현 ( Bo Hyun Hwang ),김석원 ( Sok Won Kim ),노창수 ( Chang Su Roh ) 한국화상학회 2015 한국화상학회지 Vol.21 No.4

최근 인간의 안전과 편의를 위해 무인 CCTV, 교통 모니터링, 객체 추적, 자동주행 시스템 등이 널리 사용되고 있지만 안개와 같은 자연 현상들이 영상의 색상정보를 사라지게 하여, 다양한 영상처리 알고리즘이 적용되더라도 영상을 통한 정확한 정보 획득이 어렵다. 이러한 안개와 같이 실외에서 영상의 가시성을 약화시키는 원인을 제거하기 위해 최근 여러 장의 영상을 사용하거나 추가적인 정보가 필요한 안개제거 방법이 아닌 단일영상에서의 몇 가지 안개 제거 방법이 제안되고 있다. 본 연구에서는 He 등이 제안한 dark channel prior를 랩뷰(LabVIEW)에서 구현하여 영상의 안개 보정에 적용해보고 안개제거가 중치를 조절하였을 때 안개제거의 정도를 비교하였다. Recently, unmaned CCTV, traffic monitoring, object tracking, and automatic driving systems are widely utilized for the safety and convenience however, when the natural phenomenon such as haze makes disappear the chromatic information of images, the acquisition of accurate information through image is difficult even though variety of image processing algorithms are applied. For the sake of removing such reason which deteriorate the visibility of image, few kinds of technique for the removal of haze are suggested using only one image instead of requirement of multi-images and additional informations. In this study, the dark channel prior which was suggested by He et al. was realized in LabVIEW environment and applied to correction of haze in image, and the extents of haze removal for the adjustment of weighting value of haze removal were compared.

성인의 대상포진에서 Famciclovir와 Valacyclovir의 치료 효과에 대한 비교 연구

황보현 ( Hyun Hwang Bo ),정세원 ( Se Won Jung ),손현호 ( Hyun Ho Son ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2014 大韓皮膚科學會誌 Vol.52 No.10

Background: Famciclovir and valacyclovir are antiviral agents commonly used to treat herpes zoster. These medications not only reduce the time to complete cessation of zoster-associated pain, but also aid in the healing of the herpes zoster skin lesions. However, only few studies have compared these antiviral agents. Objective: We conducted a randomized clinical trial to evaluate the extent of pain relief and wound healing, and the rate of postherpetic neuralgia associated with these drugs during 4 weeks of treatment. Methods: The study included 69 immunocompetent adult inpatients diagnosed with herpes zoster randomly divided into 2 groups based on the antiviral agent administered. Patient age, date of visit from rash onset, and rash severity at baseline were recorded. Famciclovir or valacyclovir were administered orally for 7 days. Patients reported pain levels through a visual analog scale (VAS) score, and pain durations were assessed on days 1, 3, and 7, and at weeks 2, 3, and 4. Crust formation and reepithelialization times of skin lesions were also recorded. Results: VAS scores, pain durations, ratios of patients undergoing postherpetic neuralgia, and skin lesion healing rates did not differ significantly between the 2 groups. However, rash severity independently correlated with the extent of pain experienced. Conclusion: Famciclovir and valacyclovir are comparable to each other in resolving zoster-associated pain, postherpetic neuralgia, and zoster wound healing. Early antiviral treatment before expansion of the skin lesion would be helpful for rapid relief of herpes zoster pain. (Korean J Dermatol 2014;52(10):720∼727)

ICR 마우스를 이용한 산수유 건피 추출물의 단회 경구투여 독성시험

황보현(Hyun Hwang-Bo),권다혜(Da Hye Kwon),김민영(Min Young Kim),지선영(Seon Yeong Ji),최은옥(Eun Ok Choi),김성옥(Sung Ok Kim),정지숙(Ji-Suk Jeong),홍수현(Su Hyun Hong),최성현(Sung Hyun Choi),박철(Cheol Park),최영현(Yung Hyun Choi) 한국생명과학회 2019 생명과학회지 Vol.29 No.1

산수유(Corni Fructus)는 한국을 포함한 아시아 지역에서 오랫동안 전통 의약제로 광범위하게 사용되어 왔다. 최근 연구에 따르면 산수유는 항염증, 항산화, 면역기능 조절 및 항암활성 등과 같은 많은 효능을 가지는 것으로 알려져 있다. 그러나 산수유에 대한 독성 및 안전성에 대해서는 거의 알려져 있지 않은 실정이다. 따라서 본 연구에서는 산수유 열수 추출물(CF)을 대상으로 안전성을 확인하기 위하여 단회 경구 투여에 따른 독성 시험을 실시하였다. 이를 위하여 ICR 마우스를 대상으로 1,000, 2,000 및 5,000 mg/kg의 CF를 경구 투여하였으며, 투여 후 14일 동안의 치사율, 체중 변화, 임상증상, 음수율 및 사료섭취량과 함께 부검 소견, 장기무게 변화, 혈액학 및 혈액생화학적 검사를 실시하였다. 실험 결과에 의하면 CF 투여에 따른 치사율, 임상증상, 체중 및 부검 소견 상의 유의적인 변화는 관찰되지 않았다. 또한 CF 투여에 따른 각 장기의 무게, 혈액학적 및 혈청학적 임상 화학적 지표에도 유의적인 변화는 관찰할 수 없었다. 따라서 CF 단회 경구 투여에 따른 치사량이 5,000 mg/kg 이상일 것으로 추정되어 ICR 마우스에 대하여 급성 독성이 없는 비교적 안전한 물질이라는 것을 알 수 있었으며, 향후 천연 식의 약 소재로서의 효능 규명을 통한 활용이 기대된다. Herbal medicines are widely used as therapeutic products in many countries. Corni fructus (CF), the dried ripe sarcocarp of Cornus officinalis Sieb. et Zucc (Cornaceae), has been used for thousands of years in traditional medicine and has been reported to be effective for the prevention and treatment of various diseases, such as kidney diseases and diabetes. Recent research on CF has documented a wide spectrum of therapeutic properties, which include anti-inflammatory, ant-oxidative, immunomodulatory, and anti-cancer effects. However, there is no information on its safety. Therefore, in this study, the toxicity of water extract of CF to ICR mice was investigated. The mice received a single dose of water extract of CF (1,000, 2,000, and 5,000 mg/kg of body weight) via the oral route. Mortality, clinical signs, body weight changes, gross findings, and weights of the principal organs after 14 d were then assessed. The results revealed no adverse effects of CF as determined by clinical signs, body weights, or organ weights and no gross pathological findings in any of the treatment groups. These results suggest that the 50% lethal dose and approximated lethal dose of CF extract is over 5,000 mg/kg. The findings provide scientific evidence for the safety of CFs.

2기 직장암의 예후인자

황보현 ( Bo Hyun Hwang ),박지원 ( Ji Won Park ),박성찬 ( Sung Chan Park ),김선영 ( Sun Young Kim ),백지연 ( Ji Yeon Baek ),김대용 ( Dae Yong Kim ),장희진 ( Hee Jin Chang ),최효성 ( Hyo Sung Choi ),오재환 ( Jae Hwan Oh ) 대한임상종양학회 2011 Korean Journal of Clinical Oncology Vol.7 No.2

목적: 2기 직장암에 있어서 근치적 수술 후 보조 치료의 유용성에 대해서는 의견이 분분하다. 본 연구에서는 2기 직장암의 예후인자를 분석해보고자 하였다. 방법: 2000년 10월부터 2008년 12월까지 국립암센터에서 수술을 받은 총 200명의 2기 직장암 환자를 대상으로 하였다. 단변량 및 다변량 분석을 이용하여 생존율 분석을 하였으며 이를 근거로 2기 직장암 환자의 예후인자를 예측해보고자 하였다. 결과: 2기 직장암에서 5년 생존율과 5년 무병 생존율은 각각 89.2%, 89.0% 였다. 다변량 분석을 하였을 때 5년 생존율에 영향을 주는 예후 인자는 측방절제연의 침범이었고 5년 무병 생존율의 경우 나쁜 분화도와 측방절제연의 침범이 통계적으로 유의하였다. 결론: 측방절제연의 침범 여부가 5년 생존율의 독립적인 예후인자였고 암종의 분화도와 측방절제연의 침범 여부가 2기 직장암의 5년 무병 생존율에 있어서 독립적인 예후인자였다. Background: In stage II rectal cancer, it has remained controversial whether patients get the benefit from adjuvant treatment after curative resection. The aim of this study is to evaluate the prognostic factors of stage II rectal cancer. Methods: From October 2000 to December 2008, 200 patients with stage II rectal cancer underwent surgery at National Cancer Center. Univariate and multivariate survival analyses were performed to determine the prognostic factors in stage II rectal cancer. Results: In stage II rectal cancer, 5-year overall survival and disease free survival were 89.2% and 89.0%, respectively. For overall survival, there was no significant prognostic factor in multivariable analysis. For disease-free survival, tumor differentiation and circumferential resection margin were significant prognostic factors in multivariable analysis. Conclusion: Tumor differentiation and circumference resection margin are independent prognostic factors in disease free survival of stage II rectal cancer. Adjuvant treatment may be considered in patients with these factors.

UHF 대역의 RFID 태그 설계 및 구현

황보현 ( Bo-hyun Hwang ),윤진석 ( Jin-suk Yun ),조태경 ( Tae-kyung Cho ),박병수 ( Byung-soo Park ),최명렬 ( Myung-ryul Choi ) 한국정보처리학회 2004 한국정보처리학회 학술대회논문집 Vol.11 No.1

RFID(Radio Frequency Identification) 시스템은 최근 다양한 분야로의 적용이 기대되면서, 개발이 급증하고있다. RFID 시스템은 물류관리, 보안, 유비쿼터스 등 많은 분야에서 시스템의 중추적인 기술로 사용된다. RFID 시스템을 구성하는 인터로게이터(Interrogator)와 태그(Tag)의 개발이 빠르게 진행 중에 있다. 본 논고에서는 ISO/IEC 18000-6 Type B를 만족하는 UHF 대역의 RFID 태그를 VHDL를 사용하여 설계하고 구현하였다.

피지샘 모반에서 유래한 에크린땀샘관섬유선종

황보현 ( Hyun Hwang Bo ),이택근 ( Taek Geun Lee ),정세원 ( Se Won Jung ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.9

Eccrine syringofibroadenoma (ESFA) is a rare, benign adnexal neoplasm of eccrine differentiation. It is typically located on the limbs and presents as a plaque or a solitary hyperkeratotic nodule in an adult. However, there are several clinical subtypes, ranging from a solitary papule or nodule to multiple lesions with linear or diffuse distribution. Despite the diverse clinical presentation, ESFA is histologically similar. It commonly shows proliferation of anastomosing cords and strands of cuboidal epithelial cells with or without lumina embedded in a fibrovascular stroma. Herein, we report an unusual case of ESFA with verrucous surfaced plaque present on the scalp since birth in a 22-year-old man. (Korean J Dermatol 2014;52(9):654∼657)

일반인과 교통약자의 도시철도 역사의 보행시설 이용에 관한 비교분석 (Comparative Analysis of the Use of a Pedestrian Facility for Non-Mobility Handicapped and Mobility Handicapped in Urban Rail Station)

황보현(Hyun Hwang-Bo),정헌영(Hun-Young Jung),김현웅(Hyun-Woong Kim) 한국철도학회 2011 한국철도학회 학술발표대회논문집 Vol.2011 No.5

As our society is becoming an aging society, there is an increasing number of the elderly. Recently, mobility handicapped like the elderly and the disable take part in many social activities. It is required public transportation systems for them. Already, the traffic policy for mobility handicapped including pregnant woman and child, has been established in many cities. Particularly, the convenience of mobility for the handicapped in the urban rail stations is depend on a pedestrian facilities like escalators and elevators. The pedestrian facilities have been built in urban rail stations without rules for mobility handicapped. To make the more convenient and more safe stations, the more study about mobility handicapped and non-mobility handicapped is needed. This paper preferentially discusses the pedestrian facilities with other convenience facilities in urban rail stations. This paper explains also their preference, relative satisfaction and importance for the convenience facilities including the a pedestrian facilities in urban rail stations and makes clear the difference between both groups.

전신적 인대 이완성을 동반한 소아에서 편평외반족의 수술적 치료

황보현(Bo-Hyun Hwang),이기석(Ki-Seok Lee),김현우(Hyun-Woo Kim) 대한정형외과학회 2010 대한정형외과학회지 Vol.45 No.5

목적: 전신적 인대 이완성이 동반된 소아의 편평외반족은 일반적으로 유연성이고 무증상이지만 일부에서 중증의 변형 및 기능 장애를 보인다. 본 연구의 목적은 전신적 인대 이완성 및 기능적 문제가 동반된 소아의 편평외반족에 대해 수술 후 임상적, 방사선, 족저압력 검사 결과를 분석하는 것이다. 대상 및 방법: 종골 연장술 또는 거골하 관절외 유합술을 받은 24명의 환자, 42예의 족부를 대상으로 후향적 분석을 시행하였다. 수술 시 평균 연령은 10.5세(6-15.6세), 평균 추시 기간은 51개월(18-92개월)이었다. Oxford Ankle Foot Questionnaire, AOFAS 점수 및 Mosca criteria를 이용한 임상적 평가, 족부 방사선 사진, 그리고 족저압력 검사를 이용하여 수술 전후의 결과를 비교하였다. 결과: 총 42예의 족부 중 3예를 제외하고 수술 후 우수한 임상적 결과를 보였으며, 일상 활동에 지대한 제한을 주는 경우는 없었다. 방사선 검사는 모든 평가 항목에서 수술 후 의미 있는 호전을 보였다. 족저 압력 검사상 relative vertical impulse와 peak pressure 모두 수술 후 내측은 감소하고 외측이 증가하는 소견을 보이며, 압력 중심은 내측에서 외측으로 이동하는 양상을 보였다. 결론: 전신적 인대 이완성을 동반한 소이의 편평외반족에 대해 종골 연장술 또는 거골하 관절외 유합술은 단기-중기 추사상 동통의 감소, 기능적 정해의 개선 및 해부학적인 변형의 교정에 우수한 결과를 보였다. 하지만 골격 성장 및 이완성의 변화에 따른 결과 및 술식의 후기 합병증에 대해 장기적 추시기 필요하겠다. Purpose: Planovalgus deformity in children with generalized ligamentous laxity is usually asymptomatic, but it sometimes causes severe deformity and functional problems The aim of this study was to evaluate, post-operatively, functional outcomes, plantar pressure and radiographic results of symptomatic planovalgus with generalized ligamentous laxity. Materials and Methods: This retrospective study included a total of 42 feet of 24 patients that had undergone a calcaneal lengthening osteotomy or an extra-articular subtalar arthrodesis. The mean age of the patients at the time of the index operation was 10.5 years (range, 6-15.6 years). and the mean duration of follow-up was 51 months (range, 18-92 months) Patients were evaluated clinically and radiographically using the Oxford Ankle Foot Questionnaire, AOFAS score, Mosca criteria, standard radiographs and dynamic pedobarographs. Results: Functional outcomes at the latest available follow-up were excellent except for three feet. No foot had a significant limitation affecting the patient's daily activities. Both surgical treatments improved radiographic parameters The parameters of dynamic pedobarographs, including the relative vertical impulse and the peak pressure, decreased for the medial aspect of the forefoot and midfoot, while they increased for the lateral aspect of the forefoot. midfoot and calcaneus after surgical treatment. The change in the center of pressure indicated a significant lateral shift in the weight-bearing surface of the foot. Conclusion: Calcaneal lengthening osteotomy and extra-articular subtalar arthrodesis appear to be effective means for pain relief and clinical improvement in children with symptomatic planovalgus deformity and generalized ligamentous laxity Further followup evaluation is needed to obtain long-term clinical and radiographic results with regard to skeletal maturation and changes in generalized ligamentous laxity.

시그니처 시퀀스 기반 건물 내 메시지 전달특성 측정시스템 설계

황보현(Bo-Hyun Hwang),김정호(Jeong-Ho Kim) 한국통신학회 2014 한국통신학회 학술대회논문집 Vol.2014 No.1

도계처리 단계별 도체와 처리수의 세균오염 및 염소처리 효과

이철현 ( Chul Hyun Yi ),변유성 ( You Sung Byun ),황보원 ( Bo Won Hwang ),조광제 ( Kwang Je Cho ),강호조 ( Ho Jo Kang ) 한국가축위생학회 1997 韓國家畜衛生學會誌 Vol.20 No.2

This study was carried out assess the effect of the chlorine treatment into water for processing chicken products in each stage of slaughtering, with a special viewpoint related reducing the viable number of microorganisms by which the water and the chicken body were contaminated. The mean bacterial number on chicken samples after picking process was log5.37±0.20~5.84±0.16CFU/㎠. When assessed by standard plate count method, it was the higher one than any other processing stage in which eviscerating, pinning, packaging, and chilling was followed in order of the mean bacterial number. The coliform bacterial numbers on carcasses after sampling from different processing stages were log2.11±0.63~2.88±0.25MPN㎠, which show almost similar numbers in each processing stage. But, after chilling process the number was decreased slightly. The bacterial counts in the water for scalding and chilling showed log3.43±0.59~5.06±0.21 and log 4.30±0.21~6.62±0.33CFU/ml, respectively. In the coliform counts for the water taken out from the 2nd chilling tank, the number was log1.97±0.35~2.91±0.22MPN/ml which showed higher than those of the 1st and the 3rd chilling tank water. The effect of chlorination in reducing the bacterial numbers was accepted at the residual chlorine concentration of 1mg/l by showing the reduction from 108 to 104CFU level and the numbers were decreased less than 10CFU at the concentration of 5mg/l, when assessed by viable cell counts. In conclusion, these results suggested that chlorination in chilling water with final concentration of 5mg/l was strongly recommended to reduce the bacterial numbers on final chicken products.