갈화해정탕 투여 및 운동 부하가 알콜 섭취 후 흰쥐의 혈청 지질, BUN, Creatinine 함량에 미치는 영향

韓乙珠,李鳴鍾 동국대학교 한의학연구소 2000 東國韓醫學硏究所論文集 Vol.9 No.-

갈화해정탕은 역대로 酒傷病에 쓰여진 대표적인 처방이다. 이 연구에서는 알콜 투여 후 자연회복군, 알콜 투여 후 갈화해정탕 투여군, 알콜 투여 후 운동 적용군, 알콜 투여 후 갈화해정탕 투여 운동 병행군으로 나누어 각각의 혈청 지질과 BUN, Creatinine의 함량 변화를 알아 보았다. 1. Total cholesterol 함량은 2주 후에는 갈화해정탕 투여 및 운동 병행군에서 감소하였고, 4주 후에는 갈화해정탕 투여 및 운동 병행군에서 유의성 있게 감소하였다. 2. HDL-cholesterol 함량은 2주 후에는 운동 적용군에서 유의성 있게 증가하였고, 4주 후에는 자연회복군, 갈화해정탕 투여군에서 유의성 있게 증가하였다. 3. Triglyceride 함량은 2주 후에는 운동 적용군에서 유의성 있게 감소하였고, 4주 후에는 갈화해정탕 투여군에서 유의성 있게 감소하였다. 4. Free fatty 함량은 2주 후에는 갈화해정탕 투여군에서 유의성 있게 감소하였고, 4주 후에는 갈화해정탕 투여군, 갈화해정탕 투여 및 운동 병행군에서 유의성 있게 감소하였다. 5. BUN 함량은 2주 후에는 갈화해정탕 투여 및 운동 병행군에서 유의성 있게 감소하였고, 4주 후에는 운동 적용군에서 유의성 있게 감소하였다. 6. Creatinine 함량은 2주 후에는 갈화해정탕 투여 및 운동 병행군에서 유의성 있게 감소하였고, 4주 후에는 운동 적용군, 갈화해정탕 투여 및 운동 병행군에서 유의성 있게 감소하였다. 이상의 결과로 갈화해정탕 투여 및 운동부하는 알콜 대사량 증가의 효과가 있을 것으로 생각된다. Galwhahaejungtang has beer? used to alcoholic disease. Object of This study is examining the effect of Galwhahaejungtang and exercise on variation of total cholesterol, HDL-cholesterol, triglyceride. free fatty acid, BUN, Creatinine in rat with alcohol administration. METHODS AND MATERIALS Fifty four rats were divided into four groups. 1. The group of rat with alcohol administration and no treatment 2. The group of rat with alcohol and Galwhahaejungtang administration 3. The group of rat with alcohol administation and exercise 4. The group of rat with alcohol, Galwhahaejungtang administration and exercise Serum of rat were obtained after 2 weeks and 4 weeks. RESULTS 1. The level of total cholesterol was decreased in the group of rat with Ckluhahaejungtang administration and exercise after 2 weeks. After 4 weeks, the level of total cholesterol Lvas significantly decreased in the group of rat with Galwhahaejungtang administration and exercise. 2. The level of HDL-cholesterol was significantly increased in the group of rat with exercise after 2 weeks. After 4 weeks, the level of HDL-cholesterol was significantly increased in the group of rat with no treatment and with Gulwhahaejungtang administration. 3. The level of tryglyceride was significantly decreased in the group of rat with exercise after 2 weeks, After 4 weeks, the level of tryglyceride was significantly decreased in the group of rat with Galwhahaeiungtang administration. 4. The level of free fatty acid was significantly decreased in the group of rat with Galwhahaejungtang administration after 2 weeks. After 4 weeks, the level of free fatty acid waas significantly decreased in the group of rat with Galuhbejungtang administration and with Galuhahaejungtang administration and exercise. 5. The level of BUN was significantly decreased in the group of rat with Galwhahaejungtang administration and exercise after 2 weeks. After 4 weeks, the level of BUN was significantly decreased in the group of rat with exercise. 6. The level of creatinine was significantly decreased in the group of rat with Galwhhaejungtang administration and exercise. After 4 weeks, the level of creatinine was significantly decreased in the group of rat with exercise and with Galhahaejungtang administration and exercise. CONCLUSION Based on these results, it is considered that Galwhahaejungtang administration and exercise has an accelerating effect on alcohol metabolism Key words : Galwhahaejungtang, lipid, total cholesterol, HDL-cholesterol, triglyceride, free fatty acid, exercise, BUN, creatinine, alcohol metabolism

편타성 손상후 발생한 뇌진탕증 2례

한을주,김봉찬,이명종,Han, Eul-Joo,Kim, Bong-Chan,Lee, Myong-Jong 대한한방안이비인후피부과학회 2001 한방안이비인후피부과학회지 Vol.14 No.1

Object : This study was focused on finding out the better method of medical treatment of concussion after whiplash injury. Methods : This study has been carried out for two cases of concussion after whiplash injury which had been hospitalized at the Kangnam Oriental medical Hospital of the Dongguk University Results and conclusions : The concussion is caused by whiplash injury about $47\%. In the symptoms of concussion, there are lightheadedness, dizziness, neck pain, headache, photophobia, phonophobia, anamnesis disorder, concentration disorder, tinnitus, irritability, etc. It is considered more important that the treatment of nausea and vomiting than the removal of stagnation of blood. Oriental medical treatments including of herb-medicine, acupuncture, moxibustion, cupping, chuna, taping have more economic favor and rapid effects than the others. so we report on two cases.

청열사습탕(淸熱瀉濕湯)이 관절염의 소염, 진통 및 해열작용에 미치는 영향

한을주 ( Eul Joo Han ),이명종 ( Myeong Jong Lee ) 한방재활의학과학회 2003 한방재활의학과학회지 Vol.13 No.3

Objective: This study was carried out to examine the effects of Chungyeulsaseip-tang(Qingrexieshi-tang) on anti-inflammatory, analgesic and anti-febrile on the arthritis. Methods and Materials: Each of the 8 rats were classified into normal, control, sample groups in the experiments about anti-inflammatory and anti-febrile. Each of the 8 mice were classified into normal, control, sample groups in the experiments about analgesic. Chungyeulsaseip-tang(Qingrexieshi-tang) was administered to sample group and normal saline was administered to normal and control groups. Arthritis was induced by injection of 1% carrageenan 0.1㎖and Chungyeulsaseip-tang(Qingrexieshi-tang) was administerd after 30 minutes. WBC, ESR and CRP were measured by heart puncture and NO in urine was measured in 24 hours urine. Synovium of rat`s knee was cultured with carrageenan and Dulbico`s modified Eagle`s medium and re-cultured with 2% Chungyeulsaseip-tang(Qingrexieshi-tang) for 72 hours and NO in synoviocytes was measured. Writhing syndrome was measured by Whittle`s method in the experiments about analgesic. Rectal temperature was measured by Yeast`s method in the experiments about anti-febrile. Conclusions: 1. It was recognized that Chungyeulsaseip-tang(Qingrexieshi-tang) has an anti-inflammatory effect in. 2. It was recognized that Chungyeulsaseip-tang(Qingrexieshi-tang) effectively decreases rectal temperature. 3. It was recognized that Chungyeulsaseip-tang(Qingrexieshi-tang) has an effectively analgesic function on the artificial arthritis resulted from carrageenan. According to the above results, it can be concluded Chungyeulsaseip-tang(Qingrexieshi-tang) showed the treatment effects on the artificial arthritis resulted from carageenan in rats and mice and it is suggested that more interest and study in the security for the clinical use were needed.

생체전기자율반응검사를 통한 저체중과 과체중의 특성 비교 연구

한을주 ( Eul Joo Han ),이명종 ( Myeong Jong Lee ) 한방비만학회 2002 한방비만학회지 Vol.2 No.1

Objectives: The objectives of this study is the examination of physiology of the obesity by automatic bioelectric response recorder Methods: The 86 patients below BMI 20 and the 144 patients over BMI 25 were objectives. They visited Dongguk University Kangnam oriental medical hospital from 2000. April 1 to 2001 August 30. Results: The patients below BMI 20 were accelerated a parasympathetic nerve and were decelerated a sympathetic nerve, so they loosened the tension, lacked the resistance and were oversensitive. The patients over BMI 25 were accelerated a sympathetic nerve and were decelerated a parasympathetic nerve, so they maintained the tension and the resistance.

한방병원에서의 척추 측만증 관리 방안에 대한 연구

한을주 ( Eul Joo Han ),이명종 ( Myeong Jong Lee ) 대한한의학회 한방재활의학과학회 2001 한방재활의학과학회지 Vol.11 No.4

경항통 및 요통 환자의 척추전만회복을 위한 관리

한을주 ( Eul Joo Han ),이명종 ( Myeong Jong Lee ) 한방재활의학과학회 2002 한방재활의학과학회지 Vol.12 No.1

Objectives : The purpose of this study was to investigate the clinical application of Chuna treatment on the patients suffered from cervical and lumbar pain. Whiplash injury patients caused by traffic accident are increasing in oriental medical hospital. And It is useful that Chuna treatment is applied to whiplash injury patients. Methods : This study carried out on 8 patients who have received admission or OPD treatment in Dongguk univ. Kangnam Oriental Hospital. Results and conclusions : The arrangement of spine influences prognosis. Chuna treatment made cervical and lumbar lordosis and reduced pain in this cases. The cervical and lumbar pain caused by traffic accident occurs with whiplash injury. Cervical and lumbar lordosis is reduced. Therefore Chuna is effective treatment.

서울보훈병원 한방진료과 내원환자에 대한 통계적 고찰

한을주 ( Eul Joo Han ),이명종 ( Myeong Jong Lee ) 한방재활의학과학회 2005 한방재활의학과학회지 Vol.15 No.1

Objectives : Among the patients at Seoul Veterans Hospital, there is a great demand for oriental medical treatments, and the number of patients of oriental medical part is on the increase. The purpose of this study is to show patients inclination statistically. Methods : The study was carried out on the 1045 patients came to Seoul veterans hospital from April 2003 to May 2004. Results & Conclusions : 1. Most of men patients were veterans. They had neurological disorder or cerebrovascular disease that was ongoing for 1∼5 years before diagnosis and they were treated less than 10 times. 2. Most of women patients were nursing their family. They had musculoskeletal disease that was ongoing 1 week before diagnosis and they were treated less than 10 times. 3. Under the current system, only acupuncture and other limited treatments are provided to patients due to the limited funding from the government. There were few patients who had an internal disease because they needed to be herbal treated. If the government funding were provided, they would be able to be treated.

생체전기자율반응검사를 통한 저체중과 과체중의 특성 비교 연구

이명종,한을주,Lee, Myeong-Jong,Han, Eul-Joo 한방비만학회 2002 한방비만학회지 Vol.2 No.1

Objectives: The objectives of this study is the examination of physiology of the obesity by automatic bioelectric response recorder. Methods: The 86 patients below BMI 20 and the 144 patients over BMI 25 were objectives. They visited Dongguk University Kangnam oriental medical hospital from 2000. April 1 to 2001 August 30. Results :The patients below BMI 20 were accelerated a parasympathetic nerve and were decelerated a sympathetic nerve, so they loosened the tension, lacked the resistance and were oversensitive. The patients over BMI 25 were accelerated a sympathetic nerve and were decelerated a parasympathetic nerve, so they maintained the tension and the resistance.

한방병원에 입원한 교통사고 입원환자에 대한 통계적 고찰

김봉찬 ( Bong Chan Kim ),한을주 ( Eul Ju Han ),이영준 ( Young Jun Lee ),이명종 ( Myeong Jong Lee ) 한방재활의학과학회 2002 한방재활의학과학회지 Vol.12 No.1

Objective : The purpose of this study are to find out the characteristic of patients who had admitted due to traffic accident and to promote the superiority of oriental medical treatment on the sequelae of traffic accident. Method : We analyzed statistical study in 59 patients, who had admitted to Dept. of oriental rehabilitation medicine, Kangnam oriental medical hospital, Dong Guk University from July, 2000 to June, 2001 according to medical charts. Results and Conclusions : 1. In distribution of sex and age, the rate of male was 35.6%, and that of female was 64.4%. Thirties numbered the most(13.5%) among males, and twenties numbered the most(22.0%) among females. 2. In distribution of residence, the patient who reside in Seoul numbered the most(84.7%), and who reside in Kang-nam Gu numbered the most(30.5%) among Seoul citizen. 3. In distribution of admission day, October was the most(13.5%), followed by November(11.7%), and April was the least(3.4%). 4. In distribution of onset, less than 5 days was the most(32.2%), followed by less than 2 days(27.1%), less than 10 days(15.2%). In distribution of organization of first choice, clinic is the most(13.5%) among less than 2 days and hospital is the most(13.5%) among less than 5 days. 5. In distribution of diseases, the most was C-spine sprain(72.9%), followed by L-spine sprain(55.9%), knee joint sprain(16.9%) and upper limb sprain(16.9%). 6. Mean admission days is 33.2 days, and in distribution of admission patient`s disease, rib fracture numbered the most(136 days), followed by patella fracture(79 days), compression fracture(26.5 days), contusion of head(26 days), HNP of L-spine(17.8 days).

척추간 쐐기각 변화와 추간판탈출증과의 상관 관계에 대한 연구

유석 ( Seok Yu ),한을주 ( Eul Ju Han ),이영준 ( Young Jun Lee ),이명종 ( Myung Jong Lee ) 한방재활의학과학회 2003 한방재활의학과학회지 Vol.13 No.1

Objective : The variation of intervertebral disk angle of lower lumbar vertebra is thought to be a reason of Herniation of Intervertebral Disc(IVD). The purpose of this study is to find out the relationship between variation of intervertebral disk angle of lower lumbar vertebra and herniation of intervertebral disc. Methods : The study population consisted of 57 patients who were diagnosed as HIVD by lumbar CT and evaluated with X-ray findings of L-spine lateral views. We divided patients none HIVD group(A) and HIVD group(B) by CT scan and measured lower lumbar intervertebral disk angle by L-spine lateral view. Results : According to the distribution of IVD angle by lumbar level, in the L4-5 level, A group`s average value of IVD angle is 8.37±4.03°and B group is 9.20±3.76°. In the L5-S1 level, A group`s average value of IVD angle is 9.32±4.16° and B group is 9.30±4.85°. Conclusions : Between variation of IVD angle of lower lumbar vertebra and herniation of intervertebral disc, there is no significant relationship.