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말기신부전 환자에서 심혈관계 합병증 예측인자로서의 호모시스테인의 의의
정종훈,신병철,김현리 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.2
Backgroud: Thromboembolic phenomena are major cause of morbidity and mortality in patients with end-stage renal disease (ESRD). In the last years, the accumulation of evidence coming from studies in patients with chronic renal failure have demonstrated an increased relative risk of coronary artery disease (CAD) in association with hyperhomocysteinemia. We elucidate the effects of homocysteine on diagnostic marker of cardiovascular risk factor of patients with ESRD. Methods: One hundred thirty-three patients were enrolled in the study performed at a Chosun university hospital. Ninety patients were on dialysis (58 hemodialyzed patients and 32 peritoneal dialyzed patients). Hyperhomocysteinemia was defined as a fasting plasma homocysteine level more than 15 μmol/L. Results: A total 71 patients (53.4%) had hyperhomocysteinemia. The prevalence of hyperhomocysteinemia was 60.3%, 46.9%, 48.8% among hemodialysis, peritoneal dialysis and kidney transplantation, respectively. CAD was present in 40.6% of patients (54 patients). The mean homocysteine concentration was 22.35 ± 5.94 μmol/L and 15.07 ± 5.45 μmol/L in patient with (n=54) and without (n=79) CAD, respectively (p<0.01). There was significant difference including age, serum creatinine, cardiac troponin-T (cTn-T), homocysteine level, total cholesterol, CRP in the two group (p<0.05). Plasma homocysteine concentration showed significant positive correlations with age (r= 0.261, p<0.05), cTn-T (r= 0.244, p<0.05), CRP (r= 0.422, p<0.01) in overall and negative correlations with hemoglobin (r= -0.240, p<0.05) in dialysis patients. Conclusion: Hyperhomocysteinemia, elevation of cTn-T, and elevation of CRP were diagnostic markers of ischemic heart disease of ESRD patients undergoing hemodialysis and peritoneal dialysis. The homocysteine is more potential diagnostic marker than cTn-T and CK-MB in ischemic heart disease with ESRD patients.
기독교 문화와 대학 선교 ; 연세대학교 대화채플의 현황과 앞으로의 과제
정종훈 한국대학선교학회 2005 대학과 선교 Vol.9 No.-
The Yonsei University``s Chaplain``s office had launched Panel Chapel from 2002 fall semester with the purpose of inviting good Christian figures who well reflected the Christian Spirit in their social life and listening to their vivid stories. For the first two semesters, professional announcers and panel students hosted the Panel Chapel, but the students took the initiative of designing, preparing, and conducting the Panel Chapel from the third semester to better convey young people``s interest. As of this year, three years have already passed since Yonsei University``s Chaplain``s Office has introduced Panel Chapel at its regular chapel times in 2002. During the time, the Panel Chapel at Yonsei University has established its firm position as a successful chapel. For this reason, I am quite sure that sharing the know-how of Panel Chapel at Yonsei University with other Christian universities will contribute to enhancing the quality of their chapels as well. In order to make the most effective Panel Chapel, Yonsei University keeps the following principles for its management. First, The guests at the Panel Chapel should be those who have lived a very desirable Christian life in our society, and it is recommended that the standard for the guest selection should be consistent. Second, the students from campus press (Yonsei Chunchu, Yonsei Broadcasting Service, Yonsei Visual Art Center, The Yonsei Annals) and the departments of the invited guests took the charge of conducting the Panel Chapel such as preparation, operation, and evaluation, so that they can better reflect the trend of young students around their age. Third, a subsidiary of payment, less than \300,000, is given to the students who are in charge of the Panel Chapel for financial support and encouragement. Fourth, the concerned campus press contributes to publicizing the Panel Chapel in their regular activity. For example, Yonsei Chunchu and The Yonsei Annals introduce the Panel Chapel by special report, YBS with broadcasting, and YVAC with producing visual arts. Fifth, in conducting the Panel Chapel, YBS takes the role of a MC, and the other press members (Yonsei Chunchu, The Yonsei annals, and YVAC) work as panels. Sixth, the Panel Chapel tries to be a good model of cooperation between Yonsei press clubs and Chaplain``s Office, and the students who participated in the management of it should well hand down their know-how to the prospective students. Chapel should be not degraded to a waste of time, hindering the academic pursuit of students. Rather, it needs to firmly establish its role in helping the development of their character and faith. Considering its significance in nurturing the students`` spirits, the Chaplain``s Office should exert all efforts to innovate the current chapels in meaningful ways, so that students can find more interest in them as well as invaluable benefits.
납 , 수은 및 카드뮴이 백서 좌골신경에 미치는 영향에 관한 형태학적 연구
정종훈,문연자,문철성,유태전,최민규,정연태 ( Chong Hoon Chung,Yeun Ja Mun,Chul Sung Moon,Tae Jeon Yoo,Min Kyu Choi,Yeun Tai Chung ) 한국환경생물학회 1991 환경생물 : 환경생물학회지 Vol.9 No.2
In order to evaluate the effect of some heavy metals on the sciatic nerve of the rat, light and electron microscopic studies were performed to examine the fine structural changes of sciatic nerve of the rat after administration of lead nitrate, mercuric chloride and cadmium chloride, respectively. Rats were received 200㎎/ℓ of each heavy metal(Pb, Hg and Cd) solution ad libitum for 3 months and then, they were sacrificed. The results were summarized as follows; 1. Lead nitrate-treated group showed the decreased diameter of nerve fibers and axons, and mercuric chloride-treated group showed the decrement of number of nerve fibers per unit area, remarkably. 2. g ratio (d/D) measured in the heavy metal-treated groups were 0.75 in Pb, 0.82 in Hg and 0.85 in Cd respectively, compared to the 0.78 in control group. 3. Electron microscopy of lead nitrate-treated group showed the degeneration of myelin sheath, and the destructive change of membrane of Schwann cell. 4. The severe degeneration of myelin sheath and vacuoles in axon were observed in mercuric chloride-treated group. 5. In cadmium chloride-treated group, the degeneration of myelin sheath and axon, and Schwann cell were observed. 6. Degenerative changes of axon were highest in cadmium chloride-treated group(7.4%) and also those of myelin sheath were highest in mercuric chloride-treated group(23.7%) among the experimental groups. These findings indicate that lead, mercury and cadmium produce the morphological changes in the diameters of nerve fiber and axon, and thickness of myelin sheath of sciatic nerve.
나노 Indium을 부착한 ZnO:In 가스센서의 제작 및 특성
정종훈,유윤식,유일,Jung, Jong-Hun,Yu, Yun-Sik,Yu, Il 한국재료학회 2011 한국재료학회지 Vol.21 No.9
Nano-indium-coated ZnO:In thick films were prepared by a hydrothermal method. ZnO:In gas sensors were fabricated by a screen printing method on alumina substrates. The gas sensing properties of the gas sensors were investigated for hydrocarbon gas. The effects of the indium concentration of the ZnO:In gas sensors on the structural and morphological properties were investigated by X-ray diffraction and scanning electron microscopy. XRD patterns revealed that the ZnO:In with wurtzite structure was grown with (1 0 0), (0 0 2), and (1 0 1) peaks. The quantity of In coating on the ZnO surface increased with increasing In concentration. The sensitivity of the ZnO:In sensors was measured for 5 ppm $CH_4$ gas and $CH_3CH_2CH_3$ gas at room temperature by comparing the resistance in air with that in target gases. The highest sensitivity to $CH_4$ gas and $CH_3CH_2CH_3$ gas of the ZnO:In sensors was observed at the In 6 wt%. The response and recovery times of the 6 wt% indiumcoated ZnO:In gas sensors were 19 s and 12 s, respectively.
정종훈,여환호,김수관,이준길,조경안 朝鮮大學校 口腔生物學硏究所 1999 Oral Biology Research (Oral Biol Res) Vol.23 No.2
Platelet-rich plasma is an autologous source of platelet-derived growth factor and transforming growth factor beta that is obtained by sequestering and concentrating platelets by gradient density centrifugation. This technique produced a concentration of human platelets of about 338% and identified platelet-derived growth factor and transforming growth factor beta within them. The additional amounts of these growth factors obtained by adding platelet-rich plasma to grafts evidenced increased radiographic maturation rate that of grafts without platelet-rich plasma. We have used platelet-rich plasma for bone garft, especially allobone graft, at implant surgery and sinus lift procedure. About 2 months after implantation & sinus lift procedure, panoramic view was taken an evaluated radiopacity that was one of method for bone formation. Relatively good bone formation was seen. We introduce new method of clinical using platelet-rich plasma for bone garft.