Buerger`s Disease 병인론

배진선 대한혈관외과학회 1986 Vascular Specialist International Vol.2 No.1

大腸癌의 臨床的 考察

裵振善 충남대학교 의과대학 지역사회의학연구소 1978 충남의대잡지 Vol.5 No.2

This paper is a clinical analysis and review of 40 cases of colon and rectal cancer who were admitted to Chungnam National University Hospital from July 1974 to July 1978. The results are as follow: 1. Male outnumbered female by the ratio of 1. 1 : 1 and age incidence was most pre alent in the 6th decades, comprising 45 % of all cases. 2. The duration of symptoms prior to admission was within 7-12 month in 35%. 3. The location of tumor was most frequent in recto-sigmoid colon(62. 5%), cecum (10.0%), transverse colon(10.0%) in this order. 4. Most frequent symptoms were melena (52.5%), followed by bowel habit change (45%) and pain(40%). 5. The tumors were Dukes' type A in 5% of all cases, type B 35%, type C 22.5%, and type D 37%. 6. Colostomy was most frequent operation used(30%), Miles' operation was performed in 22. 5% of all cases and right homicolectomy in 12.5% and biopsy only in 10%. 7. Complication devleoped in 25% of all cases, wound infection being most common (40%). 8. Operative mortality was 2%. 9. Dietary habit of patients seemed to be non-specific.

血淸 CEA値에 關한 臨床的 硏究

裵振善,尹必逵 충남대학교 의과대학 지역사회의학연구소 1982 충남의대잡지 Vol.9 No.2

The serum carcinoernbryonic antigen (CEA) values as an indicator of colorectal carcinoma has been accepted, however the CEA value is increased not only in colorectal cancer but in many other conditions, such as chronic pulmonary disease, heavy smoker, inflammatory bowel disease, pancreatitis, liver diseases, biliary tract disease, breast disease, ovarian disease, uterine disease, cervix disease etc. Although it may not be suitable to screening test, nevertheless its serial check is very valuable for early detection of recurrence after removal of tumor by the increase of serum CEA value during postoperative follow-up. Serum CEA values were checked by the patients of peptic ulcer, injury and other non-malignant disease, stomach cancer, breast cancer, and colorectal cancer treated from March 1982 to October 1982 in the Department of General Surgery, Chungnam National University Hospital. The following results were obtained; 1. The level in control was 2.5±1.9 ng/ml. 2. By the patients of stomach cancer, the preoperative level being 39.7±74.1 ng/ml, the postoperative level was 31.4±62.8 ng/ml. 3. By the patients of breast cancer, the preoperative level being 13.3±7.8 ng/ml, the postoperative level was 11.0±8.3 ng/ml. 4. By the patients of colorectal cancer, the preoperative level being 39.0±61.8 ng/ml, whereby the postoperative level was 21.3±35.5 ng/ml.

위암환자에서 수용성 Intercellular Adhesion Molecule-1의 의의

배진선,송인상,김완식 한국의학사 1999 診斷과治療 Vol.19 No.8

소아에서의 선천성 상완동맥 동맥류 : Case report and review of the literatures

배진선,설지영,김경헌,이영 大韓脈管外科學會 1995 大韓脈管外科學會誌 Vol.11 No.2

갑상선암의 임상적 고찰

배진선,설지영 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

Thyriod carrinoma is rare, representing approximately 1% of all malignancies but account for 90% of all endocrine malignancies. Thyroid carcinoma has a wide spectrum of biologic activity varying from nearly innocuous to very lethal malignancies. The primary treatment for thyroid carcinoma is surgical excision. But the extent of resection, indications for regional lymph node dissection, and the postoperative follow up of patients are the most controversial aspects of management. To formulate a valid rationale for the diagnosis and treatment of the thyroid cancer, a retrospective study of the thyroid cancer treated at the Department of Surgery, Chungnam National University Hospital from January, 1986 to October, 1991 was conducted. The results were as follows ; 1)By the pathological classification, the papillary carcinoma was the most common type and its incidence was 81.1% 2)Female was predminated over male by the ratio of 6.5:1 and most common age incidence was noted from fourth decade to sixth decade, that was 68.9%. 3)The most common duration of illness between the appearance of the symptoms and the treatment was 3 months, which was 31.1%. 4)The most common symptom was the palpable mass at the anterior portion of the neck. 5)Most cases of the thyroid cancer were appeared as cold nodule in the ^99m Tc-Thyroid scan, which was 98.9% in incidence. 6)The right lobe(50%)was the more common site of the thyroid cancer in comparison to the left lobe(28.9%). 7)The incidence of thyroid cancer located in the gland without extrathyroidal extension was 48.9%, and that of the metastasis to the cervical lymph nodes was 34.4% 8)The common surgical procedures of the thyriod cancer were lobectomy which incidence was 51.1%, total thyroidectomy 15.6%, near-total thyroidectomy 10.0% and lobectomy with isthmusectomy 5.6% in order respecitively. And the neck dissection was performed in 16 cases(17.7%) 9) The most common postoperative complications were transient hypoparathyroidism(11.1%), and followed by transient unilateral recurrent laryngeal nerve paralysis(10.0%), hematoma(5.6%). bilateral recurrent laryngeal nerve paralysis and permanent hypoparathyroidism.

大腸 肛門癌의 臨床的 硏究

裵振善,朴仁根 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

A clinical study was undertaken on 172 patients of colorectal and anal cancer who was admitted during 8 years from Jan. 1978 to Dec. 1985 in the Department of Surgery, Chungnam National University Hospital. The results were as followings; 1. In male, it was slight more prevalent than in female, the incidence ratio of male to female being 1.1:1. 2. As to the age distribution, the prevalent group was 10 years earlier compared with Western countries, i,e. 50 years (28.4%), followed by 40 years (25.3%), 60 years (17.9%), and 30 years (11.7%) in order of frequency. 3. The most prevalent site of tumor was rectum(55.7%), followed by sigmoid colon (8.9%), ascending colon (7.0%); 63.9% of tumors was located distal to the sigmoid. 4. The most frequent symptom was melena (55.6%), followed by abdominal pain (44.4%), change of bowel habit (36.1%) etc. 5. As to the duration of symptoms, 61% of patients was within 6 months, 80% within 1 year. 6. Hemoglobin on admission was under 10.0mg% in 26% of patients. 7. The diagnostic methods were barium enema, digital rectal examination, fiberoptic colonoscopy and sigmoidoscopy. 8. Resection was undertaken in 75% of patients; Miles' operation was most frequent (25.0%), followed by anterior resection (20.8%), and right hemicolectomy (16.7%). 9. 30.6% of patients had cancer metastasis; lymph node metastasis being most frequent (22.2%), followed by lilver metastasis (9.7%), bone metastasis (2.8%), and lung metastasis (1.4%). 10. Histologic examination revealed adenocarcinoma (95.7%), squamous cell carcinoma (2.1%), and malignant lymphoma (2.1%). 11. 33% of patients had complications, in which wound infection was most frequent (66.7%), followed by intestinal obstruction (20.8%), bladder dysfunction (16.7%), and fecal fistula (16.7%). 12. 92% of patients revealed good or excellent result, the mortality was 1.4%.

상부위장관 출혈환자의 임상적 고찰

배진선 충남대학교 의과대학 지역사회의학연구소 1977 충남의대잡지 Vol.4 No.1

82 cases of upper gastrointestinal tract bleeding admitted in department of general surgery, Chungnam National University Hospital during 4 years and 9 months from July, 1972 to March, 1977 were reviewed. The following results were obtained, 1. The incidence of upper gastrointestinal bleeding was 3.4% among all surgical inpatients during the same period. 2. The disease producing upper G-I tract bleeding were gastric ulcer(40.2%), esophageal varices (23.2%), duodenal ulcer (8.6%), stomach cancer (7.3%), acute mucosal lesions (4.9%) etc. 3. Male was predominated over female by the overall ratio of 5.3 to 1. 4. Predilection age was 5th decade (34.1%), followed by 6th decade (29.3%) 5. Operative treatment was undertaken in 58.6% of patients, while conservative treatment was in 41.4%. 6. 23.2% of patients revealed only hematemesis, 9.8% only melena and the remaining 65.9% did both. 7. Preoperative period was within 24 hrs in 33.3% and within 5 days in '70.8% of patients. 8. Postoperative period was in the range between 6 and 15 days in 71.0% of patients. 9. The admission period of patients receiving conservative treatment was within 10 days in 85% of patients. 10. Ulcer symptoms were present in 73.2% of patients in history. 11. The duration of bleeding was within 24 hrs in 48.8% of patients and within 3 days in 75%. 12. Most frequent operative procedure undertaken (excluding varices patients) was subtotal gastrectomy(61.4%) 13. Postoperative complications were bleeding (4.9%), leakage (4.9%) and fever (4.9%) etc. 14. Overall mortality was 14.6% and that for patients receiving operative treatment was 12.8% and that for conservative treatment was 24.1%.

非結石性 膽囊炎에 關한 臨床的 硏究

裵振善,睦愚均 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

A clinical study was undertaken on the 35 cases of acalculous cholecystitis among 392 cases operated for the biliary disease during the period from. January 1980 through June 1987 admitted in the department of surgery Chungnam National University Hospital. The results obtained were as followings; 1. The incidence of acalculous cholecystitis was 8.9% and extragallbladder biliary stone 3.1% among all cholecystitis. 2. The incidence of acalculous cholecystitis was slight more prevalent in female in contrast to many reports, i. e. the ratio of male to female was 1 : 1.2. 3. In regard of the age distribution, 5th decade was most prevalent, followed by 7th, 4th, & 6th decade in order of frequency; 91.4% of all patients were older than 30 years. 4. Right upper quadrant pain (74%) was most frequent clinical symptom, followed by nausea and vomiting (57%), fever & chillness (54%), & epigastric pain (37%) in order of frequency. 5. 37% of patiients was within one week of duration of symptoms, 14% between 1∼2 weeks, & 63% of patients within 4 weeks, 6. Right upper quadrant tenderness (77%) was most frequent positive physical finding, followed by jaundice (26%), & right upper quadrant mass (20%). 7. The elevated SGPT(74%) was most frequent positive laboratory finding, followed by elevated SGOT (69%), elevated serum bilirubin above 1. 5mg% (66%), above 3.0mg% (40%), leukocytosis (37%) & elevated alkaline phosphatase (37%). 8. Ileus on simple abdomen (60%) was most frequent finding as diagnostic measures, nonvisualisation of gallbladder in oral cholecystography or cholescintigraphy (17%) ; in most cases, the findings were nonspecific, therefore it can be said that clinical findings were most important in the diagnosis of acalculous cholecystitis. 9. Preoperatively, it was diagnosed as chronic cholecystitis (37%), empyema gallbladder (11%), gallbladder stone (11%), choledocholithiasis (9%), & acalculous cholecystitis (6%). i. e. the preoperative diagnostic accuracy was very low. 10. The most frequent operation underwent was cholecystectomy with or without T-tube drainage (86%), followed by cholecytostomy (9%), & choledochojejunostomy (5. 7%). 11. Bile culture was performed in 14 cases, 79% being positive, among them E. coli was most frequent (29%), followed by Klebsiella (21%), Proteus mirabilis, Streptococcus intermidius, & Streptococcus epidermidis. 12. Regarding etiologic and predisposing factors, ascaris was found in 14% of cases, Clonorchis sinensis (9%), & common bile duct cancer (9%), gallblader cancer (9%), pancreas head cancer (6%), & unclear(37%). 13. Postoperative complications were developed in 8 cases (23%), among them wound infections were most frequent (4 cases), followed by wound dehiscence (1 case), intraabdominal abscess (1 ,case), biliary fistula (1 case), & cholangitis (1 case).

小兒腹部腫瘍의 臨床的 考察

裵振善,孫鍾夏 대한적십자사 1975 적십자병원지 Vol.2 No.1