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        • KCI등재

          Sprague-Dawley 랫드를 이용한 미선나무주정추출물의 2주 반복 경구투여 독성평가

          권순복 한국식생활문화학회 2019 韓國食生活文化學會誌 Vol.34 No.6

          Abeliophyllum distichum Nakai is a deciduous shrub of a flowering plant in Oleaceae. It is an important plant resourceand consists of only one species in the entire world. A. distichum Nakai is well known an edible, medicinal herb in its habitatdistricts, but the toxicological evaluation for the safe use of its extract is still insufficient. The study characterized the toxicityof an Abeliophyllum distichum Nakai ethanol extract in Sprague-Dawley (SD) rats and determined the safe dosage levelsin a 13 weeks toxicity study. Abeliophyllum distichum Nakai ethanol extract was orally administered once daily for 2 weeksat 0, 500, 1,000 and 2,000 mg/kg/day to male and female SD rats. while recording the clinical signs of toxicity, body weight,food intake/consumption, eye test and urine analysis. Only the total protein frequency in the urine of male SD rats (p<0.05),the right ovary of the 500 mg/kg group (p<0.01) and the right adrenal gland of the 1,000 mg/kg group (p<0.05) in thefemale rats showed statistically significant changes. But no toxic effects were noted from repeated-dose administration of theAbeliophyllum distichum Nakai ethanol extract in the SD rats during the observation period. The post-mortem examinationsshowed no test substance-mediated changes. The hematological analysis and clinical blood chemistry data demonstratedno toxic effects from repeated-dose administration of Abeliophyllum distichum Nakai ethanol extract in the SD rats duringthe observation period. Based on these results, this data suggests that a dose of 1,000 mg/kg/day is a highest treatment toadminister when conducting a further 13 weeks toxicity study.

        • KCI등재

          선행연구 분석을 통한 매력적인 목소리의 특성 연구

          권순복(Soon Bok Kwon) 한국언어치료학회 2009 言語治療硏究 Vol.18 No.4

          본 연구는 매력적인 목소리에 대한 주제를 가지고 일상생활 속에서 끊임없이 접하는 목소리에 대해 많은 사람들이 궁금하게 생각해 왔던 내용들을 여러 가지 자료와 문헌들을 통해 궁금증을 해결하고자 하였다. 최근 매스컴이나 문헌에서 다루어진 내용들 중 4가지 주제로 “첫째, 좋은 목소리는 타고 나는가? 둘째, 목소리에는 어떤 정보가 담겨 있는가? 셋째, 매력적인 목소리는 과연 어떤 것인가? 넷째, 나의 목소리를 어떻게 디자인하고 가꾸어야 하는가?”에 대해 알아보고자 했다. 자료 수집은 한국교원학술정보원(KERIS)에서 제공하는 검색엔진인 http://www.riss4u.net과 미국 국립의학도서관의 검색엔진인 http://www.pubmed.gov를 이용하여 데이터베이스를 검색하였다. 본 연구 결과로는 첫째, 좋은 목소리는 선천적으로 타고 난다고 말하기보다는 말을 배우고 성장하는 시기에 부모의 발성습관이 소아의 목소리에 영향을 미치는 한 요소로 작용을 할 수는 있으나, 목소리는 타고난 것이 아니라 올바른 방법으로 가꾸고 관리함으로 좋은 목소리를 만들 수 있다. 둘째, 목소리에는 단순한 의미정보 뿐만 아니라 화자의 기분 및 감정, 대화의 수단, 몸의 상태 등을 실어서 전달하며, 개인의 성격까지를 대변해 주는 매우 영향력이 큰 의사소통의 수단임을 알 수 있었다. 셋째, 매력적인 목소리라고 하는 것은 남성은 여성의 애교 섞인 높은 톤을 선호하고, 여성은 중저음인 음성을 선호하였다. 넷째, 좋은 목소리를 만드는 방법으로는 성대가 깨끗해야하며 풍부한 화음(harmonics)과 뚜렷한 조음과 공명을 활용해서 꾸준한 훈련과 더불어 음성 사용에 있어서 오․남용을 삼가해서 성대를 보호해야하며, 꾸준한 자기관리를 통해 만들어지는 것으로 나타났다. The focus of this study is on "voice attractiveness." Its purpose is to answer the many questions people have regarding the voices they encounter in their everyday lives by referring to various data and records.The results of this study were as follows. First, it would be right to say that a good voice can be acquired by trying to have a good way of speaking and managing one's voice in a desirable way rather than to say that people are born with a good voice. However, the speaking habits of parents can influence the a child's voice while growing up and learning to speak. Second, a person's voice contains not only semantic information but also representations of the speaker's feelings and emotions. In addition, it is used as a means of dialogue and shows one's physical status. Also, the voice represents a person's personality or characteristics, and thus, it is considered to be one of the communication means having great influence and effects on how one communicates with others. Third, regarding voice attractiveness, men preferred women with a high tone and charming voice, while women preferred men with a deep and low voice.Finally, to make one's voice good and attractive, it is important to maintain clean and clear vocal cords and constantly train one's voice to have fluent harmonics and clear articulation and resonance. Also, one can have a good voice by refraining from abusing or misusing one's voice and by continuously giving it good care.

        • 성대결절 환자에서 액센트 치료법의 효과

          권순복,김용주,조철우,전계곡,이병주,왕수건 한국음성과학회 2001 음성과학 Vol.8 No.4

          Vocal nodule is one of the representative chronic diseases of vocal folds, and it can be cured by surgical removal or voice therapy. The airn of this study is to evaluate the effect of the accent method, one of the popular effective voice therapy, in the patients with vocal nodule. Authors executed the accent method in 17 patients with vocal nodule who visited the Voice & Speech Therapy Clinic, Pusan National University Hospital analysed the voice before and after treatment using the local findings, acoustic analysis and aerodynamic analysis MPT. The voice was analysed with MDVP of CSL and MPT was checked using stop watch. The parameters included Fo, Jitter, Shimmer and noise to harmonic ratio(NHR) as acoustic analysis. The results were obtained as follows. In the evaluation by the local findings, it was improved to 77% in the patients of vocal nodule. Jitter and Shimmer were shown to be improved significantly. In particular, it was shown to be improved significantly in patients with vocal nodule. As the result of this tudy, the improvement of aerodynamic aspect was more statistically significant than that of acoustic parameters. When I generalized the above mentioned results, we suggest that it is a useful voice therapy which can be helpful to the improvement of voice, applying the accent method to the vocal nodule patients, and there are currently many methods to be used in the voice therapy, but it is thought which the accent method is the good treatment as the alternatives of keeping the continuous medical treatment.

        • KCI등재

          미선나무 잎과 줄기의 성분 분석 및 안전성 평가

          권순복,강희주,김민정,김진희,신해식,김강성,Kwon,,Soonbok,Kang,,Heejoo,Kim,,Minjung,Kim,,Jinhee,Shin,,Haeshik,Kim,,Kangsung 한국환경보건학회 2014 한국환경보건학회지 Vol.40 No.3

          '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

          Objectives: This study was carried out in order to analyze the composition of the leaves and stems of Abeliophyllum distichum Nakai, with the aim of obtaining basic data for utilizing the plant as a food ingredient, as well as for processing. Methods: Leaves and stems from Abeliophyllum distichum Nakai were harvested at Cheongcheon-myeon, Geosan-gun, Chungcheongbuk-do, and were subsequently freeze-dried and ground to a fine powder for chemical component analysis and safety evaluation. Results: The moisture contents of Abeliophyllum distichum Nakai leaves and stems were respectively 65.07% and 40.97%, and the crude ash contents were 1.32% and 0.91%. In addition, the crude protein contents were 11.97% and 3.77%, and the crude fat contents were 2.52% and 0.36%, respectively. The fructose and glucose contents were 32.13 mg/g and 56.17 mg/g for leaves, and 11.38 mg/g and 10.59 mg/g for stems. The major fatty acids of the leaves were palmitic acid (31.79%) and stearic acid (14.79%), and those for stems were linolenic acid (32.78%) and palmitic acid (26.75%). The ascorbic acid contents of leaves and stems were 1.32 mg/g and 0.30 mg/g respectively. The calcium content was found to be the highest among the minerals tested, both in the leaves and stems, with the levels being 166.17 mg/100 g for leaves and 592.34 mg/100 g for stems. The content of organic acid was greater in leaves than in stems, with that of malic acid accounting for more than 75% of total organic acids for both samples. The total phenolic compounds and flavonoid contents of Abeliophyllum distichum Nakai were 50.64 mg/g and 13.53 mg/g in leaves and 96.47 mg/g and 18.53 mg/g in stems, respectively. No changes were shown in the number of micronucleated polychromatic erythrocytes (MNPCE) among 2,000 polychromatic erythrocytes compared to the negative control. Abeliophyllum distichum Nakai was administered orally to rats in order to investigate acute toxicity. The $LD_{50}$ values in rats were above 2,000 mg/kg. Conclusion: These results indicate that the leaves and stems of Abeliophyllum distichum Nakai can be used as natural ingredients in the development of nutritional and functional materials.

        • KCI등재

          언어치료학과 학과인증제를 위한 기초 연구

          권순복(Soon Bok Kwon), 김수진(Soo-Jin Kim), 배소영(So Yeong Pae), 윤혜련(Hea Ryun Yoon), 황민아(Min A Hwang), 신명선(Myung Sun Shin) 한국언어치료학회 2010 言語治療硏究 Vol.19 No.2

          본 연구는 국내 언어치료학과에 대한 자료검토를 통해 교육환경을 중심으로 하여 언어치료사를 양성하는 대학원, 학부 및 전문대학에서 시행하고 있는 자료를 수집하여 분석하고, 다른 나라의 사례를 검토한 후 언어치료학과 인증에 필요한 최적요건을 제시하고자 하였다. 연구절차는 교육환경에 해당하는 교육시설 및 장비, 학생평가, 교수진에 대한 내용을 중심으로 실태를 조사하고, 우수한 언어치료사를 배출하기 위해서 갖추어야 할 교육환경 최적평가 조건을 제안하고자 하였다. 연구대상은 2007년 교육환경과 관련된 현황자료 요청에 대하여 응답한 총 23개 학교를 대상으로 하였다. 연구결과로는 첫째, 교육시설 및 장비 측면에서는 학부와 대학원이 개설된 곳은 임상실습실 및 실험실습실을 갖추고 있었으며, 대학원만 개설된 곳은 임상 및 실험실습실을 갖추고 있는 곳이 거의 없었으며, 장비에 해당되는 실험실습 기자재는 학교마다 차이는 보였지만 주로 음성분석에 사용되는 기기들을 갖추고 있는 것으로 나타났다. 둘째, 학생평가 측면에서는 신입생 충원율 및 재학율에서는 대부분의 전공개설 학교에서는 90%이상을 유지하고 있었으며, 자격시험 합격률에서는 40%가 가장 많은 부분을 차지하였으며, 전공관련 취업률은 80%이상으로 대부분의 학생들이 전공 관련하여 취업이 이루어지는 것으로 나타났다. 셋째, 교수진 측면에서는 언어병리학전공 전임교원의 수가 다소 낮은 비율로 조사되었고, 전문대학과 대학원이 개설된 학교 중 언어병리학전공 전임교원이 없는 학교도 5곳으로 나타났다. 넷째, 교육여건의 최적평가 조건 제안 측면에서는 교육환경 분야의 인증평가 점수의 비중은 교육시설 및 장비 항목이 30%, 학생평가 30%, 교수진 항목이 40%로 교육환경 최적평가 조건을 제안하고자 하였다. This study was conducted to identify the appropriate and necessary conditions for a speech pathology certification system in a department of speech therapy by collecting and analyzing data from relevant graduate schools, undergraduate schools and colleges through which speech pathologists are trained and reviewing treatment examples in other countries, while focusing on data from domestic departments of speech therapy and the educational environment. The research was carried out by first examining the actual educational situationincluding educational facilities and equipment, student evaluation systems, and information on relevant professors, and then, by suggesting the conditions for the most appropriate evaluation on the educational environment to cultivate outstanding speech pathologists. Research subjects were 23 schools in total, which granted our request for data on the educational environment for 2007. Regarding educational facilities and equipment, universities which had undergraduate schools and graduate schools were equipped with clinical laboratories and experimental laboratories, while universities which had only graduate schools rarely had clinical and experimental laboratories. Universities also differed in the condition of their experimental and practice equipment; the equipment they had was mostly instruments for voice analysis. Regarding the evaluation of students, universities which had relevant departments maintained 90% or higher rate in the recruitment and enrollment rate. Regarding the passing rate for the relevant qualification examination, around 40% was the prevailing percentage. Also, the employment rate for graduates from the relevant departments was 80% or higher,and thus, it can be said that most of the graduates can be employed in relevant occupations. Regarding professors, the number of full-time speech pathology professors was somewhat small. In fact, five universities with colleges and graduate schools, had no full-time professors who majored in speech language pathology.Finally, in respect of suggesting the conditions for the appropriate evaluation system on the educational environment, we would like to suggest the evaluation percentage to be 30% for educational facilities and equipment, 30% for student evaluation, and 40% for professor evaluation.

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