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藿香正氣散과 少陰人藿香正氣散의 效能에 關한 實驗的 比較硏究
柳基遠,柳逢夏,尹喜植,朴東源 慶熙大學校韓醫科大學韓醫學硏究所 1998 慶熙韓醫大論文集 Vol.21 No.1
To evaluate and compare the effects of Kwakhyangjeonggisan and Souminkwakhyangjeonggisan, the effect on the extracted organ, on the ulceration, on the gastric secretion, on the intestinal movement, on the diarrehea and on the temperature were studied using mouse administered with herbal extract. The results are as follows. 1. In the effect on the extracted organs, both two prescriptions showed concentration-dependent inhibitory effect on the constriction of extracted intestines and stomach. 2. In the effect on the ulceration, Souminkwakhyangjeonggisan showed inhibitory effect on the ulcer induced by tying pylorus, while both two prescription showed inhibitory effect on the ulcer induced by Indomethacin. 3. In the effect on the gastric secretion, two prescriptions showed no significant effect on the secretion of gastric juice, while in the effect on pH, both two prescriptions showed significant inhibitory effect on the secretion of gastric acid. And in the effect on Pepsin secretion, only Kwakhyangjeonggisan inhibited Pepsin secretion with statistical significance. 4. In the effect on the movement of small intestine, Kwakhyangjeonggisan decreased the movement of small intestine, while Souminkwakhyangjeonggisan increased the movement of small intestine. And in the effect on the movement of large intestine, both two prescriptions showed inhibitory effect on the movement of large intestine. 5. In the effect on the diarrhea induced by Castor oil, both Kwakhyangjeonggisan and Souminkwakhyangjeonggisan showed inhibitory effect. 6. In the effect on the temperature, Souminkwakhyangjeonggisan showed anti-decreasing effect on normal temperature with statistical significance, while both two prescriptions showed antipyretic effect on mouse fever with statistical significance. Based on these results, it cannot be counted that Kwakhyangjeonggisan has better effect on Oegam(influenza or upper respiratory infectious deisease) than Souminkwakhyangjeonggisan. And in the light of the result that Souminkwakhyangjeonggisan showed better anti-decreasing effect on the normal temperature than Kwakhyangjeonggisan, significant stimulatory effect on the movement of small intestine, old classics discription that Souminkwakhyangjeonggisan has the effect of OnWuGangYin (warming gastrointestinal organs and descending Yin) is reconfirmed in this experimental study.
半夏白朮天麻湯 및 加味半夏白朮天麻湯의 抗疲勞效能에 關한 硏究
柳逢夏,朴東源,柳基遠,申秉澈 慶熙大學校韓醫科大學韓醫學硏究所 1999 慶熙韓醫大論文集 Vol.22 No.1
These studies were conducted to investigate the antifatigue effect of Banhabaekchoolchunmatang and Kamibanhabaekchoolchunmatang liquid extract on muscle artier swimming exercise. These studies measured the results of fatigue materials in the blood of rats before and after swimming, and compared to control group. The results of these studies were summarized as follows: 1. These studies measured the results of fatigue materials without the destruction of muscle cells. 2. After 30 minutes swimming, the lactate increase 46% on control group, Banhabaekchoolchunmatang and Kamibanhabaekchoolchunmatang worked on sample group by 37% decreation of the lactate, compare to that of control group. This result means Banhabaekchoolchunmatang and Kamibanhabaekchoolchunmatang control the lactate accumulation on muscles(p<0.05). 3. Activity level of lactate dehydrogenase was more increased by Banhabaekchoolchunmatang and Kamibanhabaekchoolchunmatang than control group. This result seems related with low lactate level by Banhabaekchoolchunmatang and Kamibanhabaekchoolchunmatang(p<0.05). 4. Activity levels of triglycerides and creatine phosphotransferase remarkably increased by swimming, but there was not considerable results by Banhabaekchoolchunmatang and Kamibanhabaekchoolchunmatang(p<0.05). 5. There were no remarkable changes of glucose level, cholesterol level by the Banhabaekchoolchunmatang and Kamibanhabaekchoolchunmatang nor swimming(p<0.05).
柳基遠,柳逢夏,鄭祐榮,朴東源 慶熙大學校韓醫科大學韓醫學硏究所 1998 慶熙韓醫大論文集 Vol.21 No.1
In order to investigate the clinical efficiency of Jungritang based on Oriental Medical References by using the experimental animals, the action of transport rates in the intestine, prevent effect of the ulcer, gastric juice secretion were studied. The results of studies were summarized as follows. 1. Jungritang was showed remarkable accelative effects on small intestinal transportability in mice, and the effect was apparent depending upon the increase of its concentration. 2. Jungritang was showed remarkable accelative effects on large intestinal transportability in mice, and the effect was apparent depending upon the increase of its concentration. 3. Jungritang was showed inhibitory intentions in the group administered 14.9mg/20g and accelative intentions in the group administered 29.8mg/20g on gastric ulcer induced by indomethacin and pyloric-ligated rats, but it was not remarkable. 4. Jungritang was showed remarkable accelative effects on acidity and pepsin output in pyloric-ligated rats, and the effect was apparent depending upon the increse of its concentration.