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박용원,한지환,박인숙,김창휘,차성호,마재숙,권태찬,이상범,김철호,이흥재,윤용수 대한소아청소년과학회 2005 Clinical and Experimental Pediatrics (CEP) Vol.48 No.10
Purpose : The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older. Methods : For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of 211 KD patients 8 years of age and older were analyzed and compared with those of the KD patients less than 8 years of age. Results : 211 patients 8 years of age and older(1.3% of total KD patients) with the mean age of 9.8 years, included 142 cases aged 8-10 years, 42 cases aged 10-12 years, and 27 cases aged 12 years and older. The male-to-female ratio was 1.9 : 1, the recurrence rate was 3.8%, and the prevalence of cases in sibling was zero. Coronary arterial(CA) abnormalities were detected by echocardiography in 25.4% of the cases, including 7.6% of CA aneurysm cases. There was 1 case complicated by myocardial infarction. Conclusion : Comparing with the data of the KD patients less than 8 years of age, data of 211 patients 8 years of age and older showed significantly higher incidences of CA abnormalities(25.4% : 19.8%) and CA aneurysms(7.6% : 4.0%). 목 적 : 치명적인 관상동맥 합병증을 일으킬 수 있는 가와사끼병에 있어, 8세 이상 소아에서의 역학 및 임상적 특성을 알아보기 위하여 본 연구를 시행하였다.방 법 : 대한 소아심장 학회의 주관하에 시행되는 가와사끼병의 국내 역학조사에서, 1994-2002년까지 9년간의 전체 환아 15,692례 중 발병 연령이 8세 이상인 환아 211례를 대상으로 하여 조사하였으며, 이를 8세 미만인 환아군과도 비교분석을 하였다. 결 과 : 전체 환아 15,692례 중 1.3%인 211례가 8세 이상으로, 평균 연령은 9.8세였으며, 8-10세가 142명, 10-12세가 42명, 12세 이상이 27명인 분포를 보였다. 남녀비는 1.9, 재발률은 3.8 %였고 가족례는 없었다. 심에코검사상 25.4%의 관상동맥 이상소견 및 7.6%의 관상동맥류 발생빈도를 나타냈으며 심근경색은 1례에서 있었다. 반면 대부분을 차지하는 8세 미만인 군은 남녀비 1.5, 재발률은 2.6%, 가족례 0.2%, 관상동맥 이상소견 19.8%, 관상동맥류 4.0%의 소견을 보였다. 결 론:8세 미만인 환아군과 비교해 본 결과, 8세 이상 환아군의 관상동맥 이상소견과 관상동맥류의 발생에 있어서 통계적으로 의미 있게 높은 빈도를 나타내었다.
자궁태반 기능부전증의 예측에 있어 Doppler 초음파검사의 유용성
박용원,조재성,김태윤,최형민,김경수,임영구 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.5
This study was designed to investigate a possible role for Doppler velocimetry as a predictor of uteroplacental insufficiency with fetal heart rate(FHR) tracing. From January 1994 to through May 1996, we studied 419 high risk pregnant women who underwent Doppler velocimetry within 1 week of intrapartum cardiotocogram or contraction stress test (CST) after 30 gestational weeks. The presence of a diastolic notch in uterine artery, elevated systolic/diastolic(S/D) ratios in umbilical artery(more than 3.0), or in uterine artery (more than 2.6) were considered abnormal. All of the 419 subjects were performed intrapartum cardiotocogram or CST within 1 week after Doppler veocimetry. Seventeen cases were associated with persistent late deceleration or positive CST. The sensitivity, specificity, positive predictive value, negative predictive value, and relative risk of umbilical artery S/D ratio for predicting abnormal FHR tracing were 23.5%(4/17), 89.3%(359/402), 8.5%(4/ 47), 96.5%(359/372), and 0.97. those of uterine artery S/D ratio and diastolic notch were 29.4%(5/17), 92.5%(372/402), 14.3%(5/35), 96.9%(372/384), 1.35 and 35.3%(6/17), 90.3% (363/402), 13.3%(6/45), 97.6%(363/374), 3.88 respectively. The presence of uterine artery diastolic notch in Doppler velocimetry seems to be a better predictor for abnormal FHR tracing after 30 weeks gestation than are S/D ratios in umbilical or uterine arteries. In conclusion, we can suggest that the presence of diastolic notch in uterine artery Doppler velocimetry might be useful to predict the uteroplacental insufficiency after 30 gestational weeks.
$Na_2O-Fe2O_3-B_2O_3-P_2O_5$ 계 유리의 도전성에 관한 연구
박용원,이경태 한국세라믹학회 1985 한국세라믹학회지 Vol.22 No.3
The composition of the base glass was determined to be $Na_2O$ 15, $Fe_2O_3$ 35, $B_2O_3$ 0~20, $P_2O_5$ 30~50 by mole percent. The heating temperature for nucleation was determined by means of thermal expansion curve. Crystalline phases were investigated by X-ray diffraction method and I.R Spectra. Electrical conductivities of glass spec-imens were observed in the temperature range 25~20$0^{\circ}C$ The activation energies of these specimens were caculated. The results obtained were as follows : 1) The limit composition of the melts 15mol% $Na_2O$ 35mole% $Fe_2O_5$ 20mole% $B_2O_3$ 30mole% $P_2O_5$ was able to be formed into desired shapes during cooling, . 2) In the measurement of d. c conductivity($\delta$) on the glasses in the system $15Na_2O-35Fe_2O_3$-$B_2O_3$-(50-x) $P_2O_5$ the values decreased by replacing 5 mole% $P_2O_5$ with $B_2O_3$ 3) The d. c conducties of heat treated samples were increased by replacing $P_2O_5$ with $B_2O_3$ 4) $B_2O_3$ contributed to precipitate crystals such as${\gamma}$-$Fe_2O_3$ $Fe_3O_4$ which had the advantage of electronic conduction in heat treated samples. 5) The slope plotted Log($\delta$) versus 1/T in this glass system was linear in the measured temperature range.