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뇨중 estrogens의 화학적인 분획 측정법에 의한 정상 월경 주기를 가진 한국 부인의 뇨중 Estrogen의 소장 및 월경주기 이상 환자의 뇨중 Estrogen치
박만용(MY Park) 대한산부인과학회 1961 Obstetrics & Gynecology Science Vol.4 No.1
저자는 뇨중 E의 화학적정량법에 의하여 정상월경주기를 가진 부인 7예에서 월경주기를 월경기, 난포기, 배란기, 황체기의 4예로 나누어 분획측정하였고 월경주기이상환자 11예에서 분획측정한 결과 그 성적은 대략 다음과 같다. 1) 정상월경주기를 가진 부인의 뇨중 E는 월경기에 가장 적고 난포기에 증가하여 배란기에 Peak를 정하고 황체기에 감소한다. 뇨중 E의 총평균은 91γ/24hrs이다. 2) 총발성무월경환자 5예중 3예는 E치가 낮고 2예는 정상이며 뇨발성무월경환자의 2예는 모두 낮다. 3) 월경불순환자 4예에서는 전예 정상범위내에 있다. 4) Estradiol, Estrone, Estriol의 각분획은 정상월경주기를 가진 부인 및 월경주기이상환자에 있어서 Estradiol이 가장 적고 Estrone은 그보다 많으며 Estriol이 가장 많은 경향을 보인다. The existing biological methods for the evalustion of estrogen have been complicated, inaccurate, furthermore, non-specific in procedures. The recent advances in the chromatography has brought the chemical methods for the evaluation of the chemical estrogen I.D. estrone, estradiol and estriol by fractional assesment. As a part of the research project in this deportment related to the various tests for the evaluation of the functions of hypophysis, thyroid gland, ovary and adrenal cortex, the evaluation of the urinary estrogen obtained from the females with regular menstrual cycles (7 cases) and with the menstrual irreguarity (11cases) by fraction technique, were carried out. The results are as follows: 1) In the females with regularity of menstrual cycles, the presence of the urinary estrogen was elicited throughout cycles, the highest levels of the same substance were maintained at the ovulation time and the lowest, being during the menstruation, avaerage levels were at 91 gamma/24 hrs. 2) In the cases with secondary amenorrhea the levels of estrogen were rather low in 3 cases out of 5, the remaining showing normal levels. In primary amenorrhea, all 2 cases revealed at lower contents. 3) In cases with irregularity, all 4 cases were observed to be maintained with normal levels. 4) The fractions of estradiol, estrone and estriol were found that the lowest levels were maintained by estradiol, the highest, by estriol.
박만용,임영석,김상도,서대교 成均館大學校 科學技術硏究所 1993 論文集 Vol.44 No.2
The formability of aluminium sheet(Al 1100), i.e., the maximum effective cup height, the uniformity of drawn cup height, the limiting drawing ratio, the thickness distribution of drawn cup and the maximum drawing load are discussed for the square and rectangular cup drawing. Two blank shapes are adopted to compare the above formabilities. One(h-bl) is designed be the slip -line theory and the other(G-bl) is the conventional shape. The five punch shape factors are considered to investigate the wide range of formability. As a result, the theoretical blank shape(h-bl) is recommended to accomplish the higher effective cup height, the larger limiting drawing ratio, the superior uniformity of drawn cup height and more smooth thickness distribution.
朴萬龍 우석대학교 의과대학 1967 우석의대잡지 Vol.4 No.1
The purpose of this study was to evaluate the alterations of the blood components in toxemia of pregnancy in Korean women. A total of 151 women, comprised of 40 normal non-pregnant adult females, 33 normal pregnant women and 78 toxemic patients, was subjected to the hematological study and chemical analysis of the peripheral blood. The toxemic patients were grouped into mild preeclampsia, severs preeclampsia and eclampsia according to international classfiration of toxemia of pregnancy by the American Comittee on Materanal Welfare. The materials were studied before delivery, and 2nd day, lst week and 3rd week after delivery respectively. Hematological studies dealt with hemoglobin, hematocrit, red blood cell-count, erythrocyte bicarbonate, calcium, inorganic phosphorus, creatinine, thymol turbidity, and fractions of the serum protein on electrophoresis. The followings are the result of the analysis that totaled 4404 cases in over all number. The normal values set forth in the present investigation correspond to those of the normal non-pregnant women, that were in the above hematological and chemical studies. 1. In the antepartum, the values of each of hemoglobin, hematocrit and red blood cells were decreased int normal pregnant women but increased in toxemic pregnant women. In the postpartum, these values returned to normal at the lst week in both mild and severe preeclampsia, and at the 3rd week postpartum in eclampsia. 2. In the antepartum, the erythrocyte sedimentation rate was markedly increased in all groups of pregnant women without significant difference by each group respectively. All of the toxemic groups still revealed higher values even at the 3rd week postpartum. 3. The blood platelets revealed no difference by each group either before or after delivery. 4. In the antepartum, the serum sodium in both severe preeclampsia and eclampsia was more decreased than in normal, In the postpartum, it returned to normal on the 2nd day in normal pregnant women, and in mild and severe preeclampsia and eclampsia at the 1st week. 5. In all groups of prognancy, the serum potassium was more decreased than in normal on the 2nd day after delivery but returned to normal at the 1st week. 6. The serum chloride revealed no difference by each group before or after delivery. 7. In the antepartum, the serum bicarbonate in all groups of pregnancy was markedly decreased which was more prominent in eclampsia. In the postpartum, it returned to normal on the 2nd day in normal pregnant women, and at the 1st week in toxemia. 8. In the antepartum, the serum calcium in all group of pregnancy was decreased except in mild preeclampsia. In all of toxemic groups, the serum calcium returned to normal at the 1st week postpartum. 9. In the antepartum, the serum inorganic phosphorus was decreased in normal pregnancy, while in mild and severe preeclampsia there was no difference of serum inorganic phosphorus from that of normal, But in eclampsia, the serum inorganic phosphorus was more increased than normal. In the postpartum, the serum inorganic phosphorus returned to normal on the 2nd day in the normal pregnancy and at the 3rd week in eclampsia. 10. In the antepartum, the serum creatinine was decreased in normal pregnancy, but was no difference from that of normal in mild preeclampsia. In both severe preeclampsia and eclampsia, serum creatinine was increased, In mild preeclamsia, and returned to normal at the 3rd week postpartum. In both severe preeclampsia and eclampsia, the serum creatinine was gradually decreased after delivery and returned to normal at the 3rd week in severe preeciampsia. But if eclampsia, higher values were still observed than those of normal at the 3rd week postpartum. 11. The thymol turbidity revealed no difference by each group before or after delivery. 12. The serum alkaline phosphatase was markedly increased in all groups of pregnancy in the antepartum without difference by each group respectively. In mild precclampsia, the serum alkaline phosphatase maintained contiuously high level even at the 3rd week postpartum, while in both severe preeclampsia and eclampsia it returned to normal at 3rd week postpartum. 13. The serum glutamic pyruvic transaminase revealed no difference by each group before or after delivery. 14. In the antepartum, the total serum cholesterol revealed no difference in normal pregnancy, while it was increased in all groups of toxemia. The serum cholesterol returned to normal at the 1st week postpartum in mild presclampsia, and at the 3rd week in both severe preeclampsia and eclampsia. 15. In the antepartum, the total serum protein was decreased in all groups of pregnancy, of which in severe preeclampsia and eclampsia it was more decreased. In all of these toxemic groups the serum protein returned to normal at the 3rd week postpartum. 16. In the antepartum, the absolute and relative concentrations of serum albumin were decreased in all groups of pregnancy. These were more so in the severe preeclampsia and eclampsia. In the postpartum the absolute and relative concentrations of the serum albumin were lower than those of normal even at the 3rd week postpartum in all toxemic groups. 17. In the antepartum, the relative concentration of serum α₁globulin was increased in normal pregnancy, and both absolute and relative concentrations were increased in all toxemic groups, In the postpartum, the absolute concentration of serum α₁globulin observed in mild preeclampsia returned to normal at the 1st week, and the relative concentration at the 3rd week postpartum. In severe preeclampsia, the relative concentration of the serum α₁globulin returned to normal at the 3rd week postpartum. In eclampsia, the absolute and relative concentrations of the serum α₁globulin returned to normal at the 3rd week postpartum. 18. In the antepartum, the relative concentration of serum α₂globulin was increased in normal pregnancy, and the absolute and relative concentrations were so in all toxemic groups. In the postpartum, the absolute and relative concentrations of serum α₂globulin observed in mild preeclampsia returned to normal at the 1st week. In both severe preeclampsia and eclampsia it returned to normal at the 3rd week postpartum. 19. In the antepartum, both the absolute and relative concentrations of the serum βglobulin were increased in all groups of pregnancy. In the postpartum, the absolute concentration of serum βglobulin observed in mild preeclampsia returned to normal at the 1st week, and the relative concentration did so at the 3rd week. In both severe preeclampsia and eclampsia the absolute concentration returned to normal at the 3rd week but the relative concentration did not return even at the 3rd week postoartum. 20. In the antepartum, the absolute and relative concentrations of serum γglobulin in normal pregrancy revealed no difference in comparison with those of normal but the absolute concentration was decreased in all groups of toxemia. In the postpartum, the absolute concentration of serum γglobulin returned to normal at the 1st week in all toxemic groups. the relative concentration of serum γglobulin observed in severe preeclampsia and eclampsia were increased after delivery and returned to normal at the 1st week in severe preeclampsia, and at the 3rd week in eclampsia. 21. The ratio of serum albumin to serum globulin was markedly decreased in all groups of the pregnancy in the antepartum. The decrease was more prominent in both severe preeclampsia and eclampsia. The ratio did not return normal at the 3rd week postpartum in all toxemic groups.
The incidence and risk factors of extrapulmonary manifestations in Mycoplasma pneumoniae pneumonia
박유경,박유나,문지은,김효빈,신미용,이 은,김철홍,이주석,이용주,김봉성,김형영,정성수,김윤선,김상영,박초롱,서주희,심정연,설인숙,성명순,송대진,안영민,오혜린,유진호,이경석,장광천,장윤영,정혜리,정은희,최성민,최윤정,한만용,김진택,김창근,양현종 대한 소아알레르기 호흡기학회 2022 Allergy Asthma & Respiratory Disease Vol.10 No.4
Purpose: Mycoplasma pneumoniae pneumonia (MP) is a major cause of community-acquired pneumonia (CAP) in children and is associated with extrapulmonary manifestations (EPM). The incidence and risk factors for EPM in children are unknown. Methods: This was a retrospective study involving 65,243 pediatric patients with CAP between 2010 and 2015 at 23 nationwide hospitals in South Korea. Medical records were reviewed to collect information regarding the clinical characteristics, radiological results, and laboratory findings. Logistic regression with multivariate analysis was performed to evaluate the risk factors associated with EPM in MP. Results: The incidence of EPM was 23.9%, including elevation of liver enzymes (18.1%), mucocutaneous manifestations (4.4%), proteinuria (4.1%), cardiovascular and neurological manifestations (0.4%), hematologic manifestations (0.2%), and arthritis (0.2%). Statistical analysis showed that mucocutaneous manifestations significantly increased with elevated alanine aminotransferase (adjusted odds ratio [aOR], 3.623; 95% confidence interval [CI], 1.933-6.790) and atopic sensitization (aOR, 2.973; 95% CI, 1.615–5.475) and decreased with respiratory virus coinfection (aOR, 0.273; 95% CI, 0.084–0.887). Elevated liver enzymes were significantly associated with elevated lactate dehydrogenase (aOR, 3.055; 95% CI, 2.257–4.137), presence of pleural effusion (aOR, 2.635; 95% CI, 1.767–3.930), and proteinuria with respiratory virus coinfection (aOR, 2.245; 95% CI, 1.113–4.527). Conclusion: Approximately 24% of pediatric patients with MP had various EPM. As the risk factors associated with each EPM were different, it is necessary to evaluate the various clinical aspects and findings of MP to predict and prepare for the occurrence of EPM.
교통사고 후 발생한 후두통의 근골격계 초음파를 이용한 침도치료 임상증례
박만용,김성하,이상미,이종덕,임진영,권소연,정일민,김성철 대한침구의학회 2011 대한침구의학회지 Vol.28 No.2
Objectives : The objective of this case report was to observe the effect of musculoskeletal ultrasound-guided acupotomy therapy on posterior headache caused by traffic accident. Methods : Musculoskeletal ultrasound-guided acupotomy therapy was performed to two patients whose brain MRI or CT results were normal, but posterior headache did not improve with general eastern medical treatment. Results : One patient’s VAS(visual analogue scale) of posterior headache was decreased for the first time after ultrasound-guided acupotomy therapy, and steadily reduced. The other patient’s VAS was also decreased for the first time after musculoskeletal ultrasound-guided acupotomy therapy. Two patient’s Korean HIT-6(Korean headache impact test-6) scores were decreased after one month. Conclusions : If general eastern medical treatment had little effect on traffic accident induced posterior headache, musculoskeletal ultrasound-guided acupotomy therapy can be applied.
완관절 다엽성 결절종의 초음파 진단을 통한 침도치료 임상증례 보고
박만용,임나라,김성하,김성철 대한침구의학회 2010 대한침구의학회지 Vol.27 No.3
Objectives : This observation was to report the clinical effects of acupotomy in treating wrist ganglion. Methods : From 7th April, 2010 to 12th May, 2010, 1 female patient who had a wrist ganglion was treated with ultra sound-guided acupotomy therapy and self moxibustion & massage. Results : The patient's wrist ganglion was disappeared on the surface of the skin after just one time acupotomy therapy. Hypoechoic lesion was turned into hyperechoic lesion on a ultrasonographic. After 1 month, a wrist ganglion was recurred, but the size of wrist ganglion was reduced. Conclusions : Acuputomy therapy has an effect of reducing the wrist ganglion size, but patient self management is important in preventing recurrence. The ganglion not visible on the surface of the skin must be considered as a treatment target.