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      • KCI등재

        사례관리를 통한 교정복지실천 방안

        박영숙 한국교정복지학회 2008 교정복지연구 Vol.- No.11

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

      • KCI등재

        일 도시 여성의 난소암에 대한 인식과 건강신념

        박영숙,박정숙 한국모자보건학회 2016 한국모자보건학회지 Vol.20 No.3

        Purpose: The aim of this study was to evaluate the baseline awareness of symptoms and risk factors for ovarian cancer and to assess health beliefs in women. Methods: Women aged over 20 to under 70 years were recruited using convenient sampling (n= 207). Questionnaire survey were included on demographics, symptoms/risk factors awareness, intention to test and health belief about ovarian cancer. Survey response rate was analyzed using SPSS Window version 21.0. Results: The level of ovarian cancer awareness was very low at an urban in South Korea. and the total score was 20~30 points. Especially, participants were not aware symptoms including indigestion, abdominal fullness and risk factors including late menopause, family history of ovarian/ breast cancer and BRCA1/2 mutation carrier. Regarding main symptoms of ovarian cancer, 82.9% of participants did not choose to visit gynecology but they wanted to visit internists. In terms of Health beliefs, overall women agreed or strongly agreed for perceived seriousness and benefit, but the score of perceived sensitivity and barriers(inversed score) were poor with 2.02, 2.40 of 4, respectively. Conclusion: Many symptoms and risk factors of ovarian cancer are not well-recognized by women. Therefore, evidence-based interventions are neeeded not only to improve women’s awareness but also to detect at early stage of ovarian cancer. The results of this study highlights with the need for efforts to improve health beliefs. 본 연구에서 한국 일 지역 여성의 난소암 증상과 위험요인에 대한 인식은 100점 만점에 30.67점, 23.47점으로 매우 낮은 수준으로 나타났다. 특히 소화불량, 오심, 복부팽만감 등의 난소암 증상과 난소암의 중요한 위험요인인 늦은 폐경, 난소암/유방암 가족력 및 BRCA1/2유전자에 대해서 대상자의 80~90% 이상이 인식하지 못하는 것으로 나타났다. 난소암 조기증상에 대한 검진의향은 상대적으로 높았으나, ‘비정상적인 질출혈’에 대해서만 부인과 진료를 선택했고, 그 외 주요증상에 대해서는 대다수가 내과 진료를 선택하였다. 난소암 관련 건강신념에서 지각된 심각성과 유익성은 4점 만점에 3점 이상으로 높은 편이었으나, 난소암에 대한 지각된 민감성은 낮고 부인과 검진에 대한 장애성은 높게 나타났다. 한국 여성들의 난소암에 대해 인식을 향상시키고 이를 바탕으로 난소암의 위험으로부터 여성 스스로가 자신을 보호할 수 있도록 하기 위하여 난소암 조기증상과 위험요인, 난소암 고위험군 선별검사 및 조기검진 등에 대한 홍보 및 교육프로그램을 개발하여 체계적으로 실행하여야 할 것이다. 또한 내과의사의 난소암에 대한 인식을 향상시키고 난소암 조기발견을 위한 내과-부인과 협력체계를 마련해야 할 것이다. 향후 연구에서는 대표성 있는 표본을 통한 대규모 조사연구와 난소암 혹은 유방암 가족력이 있는 고위험군을 대상으로 난소암 인식 및 관리 실태를 파악하는 연구가 필요하고, 더불어 난소암에 대한 사회적 관심과 효과적인 조기검진 수행을 위해 다양한 측면의 연구가 수행되어야 할 것으로 사료된다.

      • KCI등재

        출산교실에 참여한 임부의 교육 평가 및 교육

        박영숙,김영임,박연환,Park, Young-Sook,Kim, Young-Im,Park, Yeon-Hwan 한국여성건강간호학회 1996 여성건강간호학회지 Vol.2 No.1

        This study was conducted to identify the educational need of pregnant women, and to evaluate the effect of the 2-hour childbirth class provided by researchers. The subjects were composed of 183 pregnant women who participated voluntarily in the 2-hour childbirth class, and the data were collected by self reporting structured questionnaire designed by researchers. The data were analyzed with descriptive statistics, paired t test, and McNemar test by SPSS pc program. The results were as follows ; 1. Mean age of th subjects was 27 and most subjects graduated from the high school and the college. 80.3% of the subjects had nuclear family. 82.5% of the subjects were full time housewives. 2. 85.8% of the subjects were ipara. Though 71.6% of the subjects might have antepartal care in the clinic, 67.2% of the subjects had no chance to participate in the childbirth class before this study. 3. Subject's health and lifestyle, especially related to eating habits, were changed in the antepartum period. We found that the pregnancy affected positively on health and lifestyle of the women. Over 75% of the subjects became to understand the progress of labor, breath methods during the labor, and perineal exercise. Most subjects changed to think that they could control their body more actively and positively during the labor after participating in the childbirth class. 93.4% answered that 'childbirth class was necessary and important'. Most subjects wanted to be taught the contents, such as postpartum care, breast feeding, and infant care in the childbirth class. In conclusion, pregnant women to attend the childbirth educational program with their husband, and the 2-hour childbirth class provided by the researchers very effective in many aspects. Therefore we anticipated that the childbirth class on basis of pregnant women's needs will contribute to improvement of pregnant women's health and well-being during the labor.

      • KCI등재

        Regulation of IL-6 signaling by miR-125a and let-7e in endothelial cells controls vasculogenic mimicry formation of breast cancer cells

        박영숙,김종민 생화학분자생물학회 2019 BMB Reports Vol.52 No.3

        The role of tumor-proximal factors in tumor plasticity during chemoresistance and metastasis following chemotherapy is well studied. However, the role of endothelial cell (EC) derived paracrine factors in tumor plasticity, their effect on chemotherapeutic outcome, and the mechanism by which these paracrine factors modulate the tumor microenvironment are not well understood. In this study, we report a novel mechanism by which endothelial miR-125a and let-7e-mediated regulation of interleukin-6 (IL-6) signaling can manipulate vasculogenic mimicry (VM) formation of MDA-MB-231 breast cancer cells. We found that endothelial IL-6 levels were significantly higher in response to cisplatin treatment, whereas levels of IL-6 upon cisplatin exposure remained unchanged in MDA-MB-231 breast cancer cells. We additionally found an inverse correlation between IL-6 and miR-125a/let-7e expression levels in cisplatin treated ECs. Interestingly, IL-6, IL-6 receptor (IL-6R), and signal transducer and activator of transcription 3 (STAT3) genes in the IL-6 pathway are closely regulated by miR-125a and let-7e, which directly target its 3’ untranslated region. Functional analyses revealed that endothelial miR-125a and let-7e inhibit IL-6-induced adhesion of monocytes to ECs. Furthermore, conditioned medium from cisplatin treated ECs induced a significantly higher formation of VM in MDA-MB-231 breast cancer cells as compared to that from intact ECs; this effect of cisplatin treatment was abrogated by concurrent overexpression of miR-125a and let-7e. Overall, this study reveals a novel EC-tumor cell crosstalk mediated by the endothelial miR-125a/let-7e-IL-6 signaling axis, which might improve chemosensitivity and provide potential therapeutic targets for the treatment of cancer.

      • KCI등재후보

        상호작용성 가상체험 기법을 이용한 청소년 사이버 성교육 프로그램 개발 및 효과 검증 연구

        박영숙,강미경 한국청소년상담복지개발원 2003 청소년상담연구 Vol.11 No.1

        Knowledge on sex and attitude are frequently asked questions and problems in cyber counseling and general sex education for adolescents. The purpose of the present study is to develop online sex education program and test its effectiveness. Five counselors and educators selected four subjects that were judged to be the most suitable for this program: temptation on pornography and its addiction, masturbation, birth control, and sexual intercourse. Those subject areas were incorporated into the program in the form of flash animations to make the program approachable and attractive to adolescents. 183 middle school students were served as a controlled group. 522 middle school students out of 995 total participants who participated in the program served as the treatment group. The average scores of the two groups regarding sexual knowledge and attitude were compared in the four subject areas. The participants of online sex education program showed higher averages on every subject. The result indicated that the program is effective in changing sexual knowledge and attitude of adolescents. 본 연구에서는 사이버 상담 및 일반 교육 장면에서 청소년들에게 빈번하게 발생하고 있으며, 문제 해결이 요구 되는 청소년들의 성지식, 성태도의 내용을 ‘문제해결 중심의 가상체험1)적’ 성교육 실행 프로그램으로 개발하고 그 효과를 검증하고자 하였다. 이를 위하여 청소년 성상담 및 성교육 전문가 5인이 3차에 걸친 주제 선정 회의 를 거쳐 청소년 성상담 사례 빈도가 가장 높고 상호작용과 가상체험에 적합하다고 판단되는 ‘음란물 중독, 피임, 자위행위, 성적 자기결정’을 주제로 결정하였고 이는 주요 사용자인 청소년이 호감을 갖고 능동적으로 접근할 수 있도록 플래시 애니메이션2)의 형식으로 제작하였다. 가상체험적 사이버 성교육 프로그램의 효과측정을 위해 프로그램에 참여하지 않은 통제집단 (서울시 M중학교 재학생 183명)과 인터넷을 통해 프로그램에 참여한 실험 집단 (전체 참여자 995명 중 중학생이라고 응답한 522명)을 조사 대상으로 하였다. 효과 측정을 위해 제작된 측 정도구를 활용하며 두 집단의 4개 주제별 성지식 및 태도의 점수를 비교한 결과 모든 영역에서 실험집단의 평 균점수가 더 높아 본 연구에서 개발한 가상체험적 프로그램이 청소년의 성지식 및 태도 변화에 효과적인 것으 로 나타났다.

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