鬱血性心不全의 診斷과 治療(2)

朴熙明 최신의학사 1976 最新醫學 Vol.19 No.8

結核性 肺肋膜 疾患의 肺臟機能에 關한 硏究 : 第四編 GAS擴散에 關하여 Ⅳ. On Diffusion

朴熙明 慶北大學校 醫科大學 1961 慶北醫大誌 Vol.3 No.1

The measurement of the diffusing capacity of oxygen across the alveolo-capillary membrane is extremely important for the full evaluation of pulmonary function. However, too little attention has been directed to the diffusion of gas in the lung tissue, largely because of complaxity and impracticability of the methods available. Ornstein's rebreathing bag method is a rather simple and easily applicable in practice, and offers fairly reliable results for the clinical purposes although it does not allow the direct measurement of the diffusing capacity. The method consists of the determination of oxygen and carbon dioxide contents of the gas in the bag, initially filled with room air, after 20 seconds in the bag after 15 seconds rebreathing as well as 20 seconds to increase the diagnostic value and to overcome disadvantage of this method inherent to single gas analysis, and following results were obtained. 1) In 100 normal Koreans, the mean oxygen contents of the gas in the bag after 15 and 20 seconds rebreathing were 9.41% and 8.02%, respectively. 2) Diffusion disturbance (abnormally high oxygen contents) was found in 20 cases (21.3%) out of 94 with tuberculous pleuro-pulmonary diseases on whom both 15 and 20 seconds data were observed. In these 20 cases, six were discovered only by observing 15 seconds data, suggesting that two observations (15 and 20 seconds) are superior to single determination. 3) Diffusion difficulty was found in 29 cases (12.8%) out of 225 on whom only Ornstein's original method was tested. 4) The incidence and degree of diffusion difficulty showed no close correlation with extent of disease process or severity of dyspnea.

結核性 肺肋膜 疾患의 肺臟機能에 關한 硏究 : 第二編 換氣에 關하여 Ⅱ. On Ventilation

朴熙明 慶北大學校 醫科大學 1961 慶北醫大誌 Vol.3 No.1

Normal values of vital capacity and maximal breathing capacity based on an analysis of 141 healthy Korean males and females were presented. Vital capacity, maximal breathing capacity, minute volume (resting, sitting and during exercise), breathing reserve ration (resting and during exercise) and ventilatory reserve were determined on 225 patients with tuberculous pleuro-pulmonary diseases, and the results were compared according to sex, extent and type of disease process, and degree of dyspnea on exertion. The averages of the percentage of observed vital capacity and maximal breathing capacity to the predicted in normal Korean males calculated by Baldwin et al formulae were 104.1% and 110.0%, respectively, indicationg that Baldwin et al formulae underestimate those of Korean males. The averages of the percentage of observed vital capacity and maximal breathing capacity to the predicted in healthy Korean females calculated by Baldwin et al formulae were 101.5% and 96.0%, respectively, indicating that Baldwin et al formula predicts accurately the former but overes timate the latter. Vital capacity was diminished in all groups of patients, regardless of extent and type of disease process, and severity of dyspnea on exertion, except for patients with minimal pulmonary tuberculosis and those with no dyspnea on exertion. Maximal breathing capacity was decreased in patients with pleurisy, moderately advanced pulmonary tuberculosis in females and far advanced pulmonary tuberculosis in both sexes, Also noted was a decrease in patients with dyspnea on slight to moderate exertion in both sexes. Minute volume in resting, sitting and during exercise showed no close correlation to the extent and type of disase process and severity of dyspnea on exertion. Breathing reserve ratio and ventilatory reserve were decreased in patients with pleurisy, moderately advanced pulmonary tuberculosis in females, far advanced pulmonary tuberculosis in both sexes, and those with dyspnea on slight and/or moderate exertion in males and females. The decrease in breathing reserve ration and ventilatory reserve was caused in almost all cases by a decrease of maximal breathing capacity, thus suggesting that a separate determination of these beside the maximal breathing capacity measurement has no particular significance. The decreases of vital capacity, maximal breathing capacity, breathing reserve ratio and ventilatory reserve were roughly proportionate to the extent of disease process and severity of dyspnea on exertion. However, the decrease was more marked in female patiento compared to males, probably resulting from less patience and relatively severer general weakness caused by the same extent of disease process in females.

스낵류 패키지 디자인에 나타난 펀(Fun)의 시각적 표현 연구

박희명,이철 한국일러스트레이션학회 2022 일러스트레이션 포럼 Vol.23 No.71

The modern consumption tendency is changing from simple consumption to purchase necessary products to value-oriented consumption that provides psychological satisfaction. Value-oriented emotional consumption that fits one's taste and preference, especially in snacks, stimulates consumers' emotions with laughter and pleasure, adds value to products, and promotes consumption. This study analyzes the types of visual elements of package design targeting the top 12 snack products in the sense that fun has a role to deliver fun and laughter and has meaning as a marketing tool, and identifies the emotions expressed in the contents and methods of fun. Therefore, we tried to find a significant value. As a result of the analysis, in the fun snacks, there were many descriptive names that could easily identify the properties of the product, and the Gothic font was mainly used for the logo. Characters are a representative way to induce laughter, and there were many humorous expressions containing light laughter or fun. In addition, the sensitivity to novelty that had not been experienced or reinterpreted familiarity was highly evaluated. Fun expressed in snacks has different results depending on the method, but fun design is expected to be expressed in various product groups besides snacks in that laughter and fun create a positive effect and purchase reason for the product. 현대의 소비 성향은 필요한 제품을 구매하는 단순 소비에서 심리적 만족을 주는 가치 중심 소비로 변하고 있다. 자신의 취향과 기호에 맞는 가치 중심의 감성적 소비 현상은 특히, 스낵류에서 보여지는 Fun한 표현이 웃음과 즐거움으로 소비자의 감성을 자극하고 제품에 가치를 부여하며 소비를 촉진시키고 있다. 본 연구는 Fun이 재미와 웃음을 전달하는 역할과 마케팅 수단으로서 의미를 갖는다는 점에서 스낵류 매출 상위 12개 제품을 대상으로 패키지 디자인의 시각요소 유형을 분석하고 Fun의 내용 및 방법에서 나타나는 감성을 파악하여 유의미한 값을 찾고자 하였다. 분석 결과, Fun한 스낵류에서 네이밍은 제품의 속성을 쉽게 파악할 수 있는 서술형이 많았으며 로고는 고딕체가 주로 사용되었다. 캐릭터는 웃음을 유발시키는 대표적인 방법으로, 가벼운 웃음이나 재미를 담고 있는 해학적인 표현이 많았다. 또한 익숙함을 재해석하거나 경험하지 못했던 새로움에 대한 감성이 높게 평가되었다. 스낵류에서 표현되는 Fun은 방법에 따라 결과의 차이는 있으나 웃음과 재미가 제품에 긍정적인 효과와 구매 이유를 만든다는 점에서 Fun한 디자인이 스낵 외에도 다양한 제품군에서 표현되기를 기대한다.

心臟技能檢査法에 關하여

朴熙明 대한의학협회 1962 대한의학협회지 Vol.5 No.7

結核性 肺肋膜 疾患의 肺臟機能에 關한 硏究 : 第一編 臥位 運動時의 酸素攝取量 및 換氣當量에 關하여 Ⅰ. On Oxygen Consumption and Ventilation Equivalent

朴熙明 慶北大學校 醫科大學 1961 慶北醫大誌 Vol.3 No.1

A study was carried out to evaluate the clinical and pathophysiological significance of oxygen consumption and ventilation equivalent in tuberculous pleuro-pulmonary diseases based on an analysis of 225 cases in lying and sitting position, and during exercise. Oxygen consumption in lying and sitting position showed no significant difference, regardless of type and extent of disease process, and degree of dyspnea on exertion, from that of normal value. During exercise, however, a marked decrease was noted in patients, particularly in those with moderately to far advanced pulmonary tuberculosis, pleurisy, and with dyspnea on slight exertion. Ventilation equivalent showed marked individual variation but the mean values in lying and sitting position were about the same as those of normal, without close correlation to extent and type of disease process, and degree of dyspnea on exertion. However, it was higher than normal during exercise, particularly in those with far advanced pulmonary tuberculosis, pleurisy, and with dyspnea on slight exertion, probably as a result of decreased oxygen uptake in these groaps of patients. The fact that oxygen consumption and ventilation equivalent showed significant difference from those of normal only during exercise is probably due to impaired functional reserve of the lung, which emphasizes the importance of exercise test for the evaluation of pulmonary function.

人工心肺裝置에 關하여

朴熙明 대한의학협회 1961 대한의학협회지 Vol.4 No.10

Comparison of Two Methods for the Extraction of Lactoferrin-binding Proteins from Streptococcus uberis

박희명,Jong-hyun Yoo,Ra? A. Almeida,Stephen P. Oliver 한국임상수의학회 2007 한국임상수의학회지 Vol.24 No.3

A case of adrenal gland dependent hyperadrenocorticism with mitotane therapy in a yorkshire terrier dog

박희명,Young-Mi Lee,Byeong-Teck Kang,Dong-in Jung,Chul Park,Ha-Jung Kim,김주원,Chae-Young Lim,Eun-Hee Park 대한수의학회 2005 Journal of Veterinary Science Vol.6 No.4

Hyperadrenocorticism, a disorder characterized by excessive production of cortisol by the adrenal cortex, is wellrecognized in dogs. A 10-year-old, intact male, Yorkshire terrier dog was evaluated because of corneal ulceration and generalized alopecia. Diagnosis was made based on history taking, clinical signs, physical examination, and results of routine laboratory testing (complete blood count, serum biochemical analysis, and urinalysis). In addition, adrenocorticotropic hormone (ACTH) stimulation test and abdominal ultrasonography were also used to diagnose this case. The patient was diagnosed as adrenal gland neoplasia and medical therapy using the adrenocorticolytic agent, mitotane, was initiated. An ACTH stimulation test was performed after initial therapy. After successful induction was obtained, maintenance therapy with mitotane still continued.

갑상선기능항진증의 임상적 관찰

박희명,송석호,이규보,황기석,강반 대한핵의학회 1969 핵의학 분자영상 Vol.3 No.2

1962년 1월부터 1968년 6월까지 6년 6개월동안에 경북의대 부속병원 방사성동위원소과에서 진료한 갑상선질환 환자 가운데 갑상선기능항진증 161예 (14.5%)에 대한 임상적관찰에서 다음과 같은 성적을 얻었다. 1) 갑상선기능항진증의 남녀비는 1:4.6이었고 연령별로는 30∼39세가 전예의 35.4%로서 가장 많았으며 그 다음은 40대, 50대, 20대의 순이었다. 2) 선종은 미만성선종이 144예, 결절성선종이 17예였으며 미만성선종에서의 남녀비는 1:4.3이었고 결절성선종에서의 남녀비는 1:7.5이었다. 3) 임상증상은 허약감, 역피로감, 심계항진, 체중 감소, 신경과민, 발한, 열불내성, 식욕증진, 불면증, 월경불순등이었고 타학적 소견으로는 선종, 미세진전, 빈맥, 맥압차의 증가, 수척, 온습피부, 안구돌출증, 수축기성고혈압 및 심방세동등의 순으로 흔히 볼 수 있었으며 합병증으로는 ophthalmopathy 및 갑상선기능항진성 심장병이 각각 전예의 34.2% 및 5.6%에 있었고, 그밖에 갑상선분리가 1예, pretibial myxedema가 1예, thyrotoxic myopathy가 1예 있었다. 4) (131)^I 갑상선섭취율은 미만성선종에서는 6시간 및 24시간치의 평균치가 각각 67.5% 및 71.6%이었고 결절성선종에서는 평균 64.5% 및 65.0C가 가장 많았다. 6) 치료후에 임상증상이 호전 또는 소실하는 순위는 열불내성, 수척, 신경과민, 불면증, 역피로감, 허약감, 심계항진, 미세진전, 선종, 발한등의 순이었으며, 안구돌출증도 호전 또는 소실된 예도 있었다. 7) 치료후 점액수종이 발생한 예는 4예 (3%)였고 재발된 예는 9예 (6.8%)였다. A clinical analysis was made on 161 cases of hyperthyroidism seen at the Radioisotope Laboratory of Kyungpook National University Hospital. This series consisted of 144 cases of diffuse goiter and 17 cases of nodular goiter. 1) Hyperthyroidism was most prevalent in the 4th decade and male to female ratio was 1:4.6. 2) Cardinal symptoms in the order of frequency were weakness, easy fatigability, palpitation, weight loss, nervousness, perspiration, heat intolerance, increased appetite, insomnia and dysmenorrhea. 3) Major physical findings in the order of frequency were goiter, fine tremor, tachycardia, wide pulse pressure, emaciation, warm moist skin, exophthalmos, systolic hypertension and atrial fibrillation. 4) The complications were ophthalmopathy (34.2%), thyrotoxic heart disease (5.6%), thyroid crisis (1 case), pretibial myxedema (1 case) and thyrotoxic myopathy (1 case). ( 5) Mean values of the six hour and twenty-four hour (131)^I uptakes by the thyroid glands were 67.5% and 71.6%, respectively, in diffuse goiter and 64.5% and 65.0%, respectively, in nodular goiter. 6) Mean values of twenty-four PB(131)I conversion ratio were 76.3% in diffuse goiter and 70.2% in nodular goiter and those of the basal metabolic rate was +51% in the former and +41% in the latter. Mean serum cholesterol level was 152mg% in diffuse goiter and that in nodular goiter was 175mg%. 7) Among the 134 cases treated with 131I, 66 cases (49.3%) were successfully controlled with single dose and in the majority of the cases the initial therapeutic dose required was 4.1∼4.0mC in diffuse goiter and 5.1∼6.0mC in nodular goiter. 8) With (131)^I treatment the symptoms improved in the following order:heat intolerance, emaciation, nervousness, insomnia, easy fatigability, weakness, fine tremor, goiter, perspiration, exertional dyspnea and palpitaion. And in a few cases improvement of even exophthalmos was seen. 9) Following (131)^I treatment myxedema occurred in 4 cases (3%) and reccurrence in 9 cases (6.8%). $quot;