운동유발성 천식환자에서 운동후 요중 메틸히스타민 및 설피도펩티드 류코트리엔의 농도 변화

박재경,반준우,이병재,손지웅,이상록,김윤근,조상헌,민경업,김유영 (Jae Kyung Park,Jun Woo Bahn,Byung Jae Lee,Jee Woong Son,Sang Rok Lee,Yoon Keun Kim,Sang Heon Cho,Kyung Up Min,You Young Kim) 대한천식알레르기학회 1998 천식 및 알레르기 Vol.18 No.1

Background: Exercise can aggravate asthmatic symptoms in many patients with bronchial asthma. It is caused by that inhaled air bypasses nasal cavity and goes directly to the lower airways through open mouth dring exercise. Although the pathogenetic mechanisms of exercise -induced asthma(EIA) have not been clarified yet, there is evidence that chemical mediators, released from the inflammatory cells triggered by airway cooling or drying, might be responsible for induction of bronchoconstriction. However, it has been controversial which chemical mediators or cells are involved in such process. Objectiye . The aim of this study was to evaluate t.he role of activated mast cells in the pathogenesis of EIA and find out whether or not sulfidopeptide leukotrienes (LTC4/d4/E4) are involved in the exercise-induced bronchoconstriction. Material and Method: Eleven asthmatics with documented exercise-induced bronchoconstriction and 10 control subjects were studied. Before and 6 hours after free running for 6 minutes, forced expiratory volume in 1 second (FEV,) and the concentrations of N- methylhistamine, LTE4, and creatinine in unine collected for 6 hours after exercise were determined. Result: Urinary concentrations of N-methylhistamine(mean+SE, ng/mg creatinine) of EIA patients before and after exercise were 159+40 and 450+75, respectively. Those of control subjects were 208+ 54 and 275+ 62, respectively. Uninary N-methylhistamine levels of EIA group increased significantly after exercise, while those of control group did not change. Urinary concentrations of LTE,(mean+SE, pg/mg creatinine) of EIA patients before and after exercise were 15.6 k2.6 and 22.2+5.8, respectively. Those of control subjects were 10.4+ 4.0, 18.2 +7.0, respectively. The concentrations of LTE4 in the urine samples collected before exerise revealed no difference between EIA and control subjects (p=0.07). There was no change after exercise in both groups. Percent fall of FEV, was 29.1+8.0% (mean+SD) in EIA group and 3.4 + 4.0% in control group, respectively. There was no correlation between reduction of FEV, and change in urinary concentrations of N-methyl-histmine after exercise. Conclusion'. Chemical mediators of activated mast cells may be involved in exercise-induced bronchoconstriction, but there is little evidence for enhanced sulfidopeptide leukotriene generation as assessed by urinary LTE4.

주정환자에서의 피부질환의 조사

박재경,김상원 ( Jae Kyung Park,Sang Won Kim ) 대한피부과학회 1990 大韓皮膚科學會誌 Vol.28 No.5

N/A The Sttudy of Skin Disorders in Alcoholic Pationts Jae Kyoung Park, M.D., Sang Won Kim, M.D. Department of dermatology, Catholic Hospital, Taegu, Korea We performed the comparative dermatologic study in 225 alcoholic patients(217 male, 8 female) diagnosed upon psychiatric grounds and in 227 normal heathy controls to evaluate the cutaneous effect of alcohol during a 4-month period from April to july, 1988 and the same month period in. 1989. The mean age of alcoholic patients was 46.5 years(male : 46.7, female : 40.8), being most prevalent in the 4th to 6th decades. The number of skin disorders was 1.7 per person in patients and 1.4 in controls. There were infections with fungal, bacterial and viral agents in 180, dermatitis and eczema in 69 spider angioma in 29, and nail changes in 22, revealing slightly more prevalent than those in controls(80.0% vs 77.5%, 30.7% vs 25.1%, 12.9% vs 7.9%, 98% vs 4.4%). Rosacea showed no difference between two groups(10.0% vs 10.1%). The prevalence of oral manifestations, tattoo, penile foreign body and melanoderma were low, but showed highly meaningful results. Tinea infection and seborrheic dermatitis were much commonly observed, and chronic gingival inflammation with tongue changes and clubbing fingers were remarkable. It was suggested that skin disorders in alcoholic patients may be the secondary events to failure of self-management, poor personal hygiene, nutritional deficiency and/or internal disorders associated with alcohol abuse than the direct cutaneous effect of alcohol.

오령산(五?散)으로 호전된 일차성 불면증 1례 임상 보고

박재경,Park, Jae Kyung 대한상한금궤의학회 2015 대한상한금궤의학회지 Vol.7 No.1

Objective : This case report aims to demonstrate the effect of Oryeong-san on Insomnia. Methods : A 26 year old woman suffered from insomnia with mental and physical exhaustion, reduced stamina, lack of concentration in daytime. According to Diagnostic system based on Shanghanlun provisions, the patient was diagnosed with Taeyang-byung and treated by Oryeong-san decoction. The result of administration was evaluated by Insomnia Severity Index. Results : After administration of Oryeong-san decoction for 1 month, Insomnia Severity Index was decreased from 24(clinical insomnia, severe) to 1(no clinically significant insomnia). Conclusions : The patient completely recovered from insomnia and daytime symptoms as treated by Oryeong-san decoction according to Diagnostic system based on Shanghanlun provisions.

PSM기반 중소도시 주상복합 아파트의 분양가 추정에 관한 연구

박재경,조용경,이상엽,Park, Jaekyung,Cho, Yongkyung,Lee, Sangyoub 한국건설관리학회 2014 한국건설관리학회 논문집 Vol.15 No.4

주상복합 아파트는 고급화와 다양한 장점으로 꾸준히 수요가 증가하여 수도권을 중심으로 지속적으로 공급되어 왔다. 지방중소도시의 경우에는 선례도 부족하고 성공을 담보할 수 없어 주상복합 아파트의 공급이 거의 이루어지고 있지 않았다. 현재에는 소득수준이 높아진 지방중소도시에 주상복합 수요가 있으며, 수도권 주택 공급이 포화된 현실에서 새로운 사업으로써 지방중소도시 주상복합 아파트의 공급 사업을 고려할 수 있다. 그러나 사업성의 타당성 분석을 위한 지방중소도시 주택 시장의 기본적인 자료나 관련한 연구가 거의 없는 실정이다. 이에 타당성 분석의 기초가 되는 적정 분양가격을 과거 시장가격이 없는 경우에도 적정가격을 추정할 수 있는 PSM 모델을 활용하여 추정하였다. 더불어 이러한 분양가격과, UTP를 통한 가격의 수요 탄력성, 가격결정 요인을 일반 아파트와 주상복합 아파트의 두 경우로 구분하여 각각 도출하고 시사점을 제공하고자 하였다. 분석결과 OPP 기준으로 봤을 때 주상복합 아파트의 분양가가 일반 아파트의 분양가에 비해 10.8% 높게 추정되었다. UTP도 주상복합 아파트가 높은 것으로 나타났으며 일반아파트 보다 주상복합 아파트의 가격민감도가 낮은 것으로 나타났다. 가격결정 요인 분석 결과는 일반 아파트와 주상복합 아파트 모두 응답자 연령, 교육수준이 유의한 것으로 나타났으며 주상복합 아파트의 경우 가족 수도 유의한 것으로 나타났다. 연구의 결과를 통해 실무적으로 활용이 가능한 분양가 추정 방법의 제시 뿐만 아니라, 지방중소도시에 주상복합 아파트를 공급할 경우 기존의 일반 아파트에 비해 높은 가격으로 분양가를 산정할 수 있다는 사실을 확인하였다. 더불어 수요탄력성이나 가격결정 요인 등의 결과를 주택 상품 기획을 위한 마케팅 분야에도 활용을 기대할 수 있다. Since the late 1990s, mixed-use apartment, armed with high qualities and large scales with a high ratio of TFA(Total Floor Area) have been continuously provided accommodating exclusive community facilities along with high-tech securities, not to mention excellent skyline view. However, especially in mid-small cities, there have been only a few supplies. As a result, none of the mixed-use housing provided by high-end brands has ever been built in non-metropolitan area. But constructors couldn't plan the projects which aims to build the mixed-use apartment in local city, because they couldn't get the basic data or advanced research for feasibility analysis. Therefore, to suggest the useful price for mixed-use apartment supply project of local city, the PSM(Price Sensitivity Method) widely used for determining the price preferences as a market research tools has been applied. As analysis results, the estimated price of mixed-use apartment is 10.8% higher than general apartment, and mixed-use apartment has lower price sensitivity than general apartment. As price determinants, the age, education level and family size influence on UTP in significant level. It is expected that these research findings can be applied for establishing the solid marketing strategy of mixed-use apartment development project in local city.

주입선 형태가 티타늄 주조관의 변연재현성에 미치는 영향

박재경,정창모,전영찬,Park Jae-Kyoung,Jeong Chang-Mo,Jeon Young-Chan 대한치과보철학회 2002 대한치과보철학회지 Vol.40 No.4

There has been a great interest in the use of titanium for fixed and removable prostheses in recent because of its excellent biocompatibility. However the high melting temperature and chemical reactivity of titanium necessitates casting systems different from those used in conventional casting. The current titanium casting systems are based on an electric-arc design for melting the metal in an argon atmosphere and its exclusive investment. Despite the new developments in Ti casting systems, inadequate mold filling and internal porosity are frequently observed casting defects. Therefore, the study on the fabrication technique including sprue design to solve these casting defects is still necessary. In this study to evaluate the effect of sprue design on the castability of simulated cast titanium crowns, 10 cylindrical cast crowns for each group with four different sprue design(Single group. Double group, Runner bar group. Reservoir group) were fabricated. An impression of the entire casting margin was made and cut at $90^{\circ}$ intervals, and the sections were photographed in a microscope at $100{\times}$ magnification to record marginal discrepancy. The internal porosities of the cast crowns were disclosed by radiographs. Within the limits of this study. the following conclusions were drawn. 1. The overall mean marginal discrepancies for each group were as follows: Double group, $43.65{\mu}m$; Reservoir group, $50.27{\mu}m$; Single group, $54.17{\mu}m$; Runner bar group, $58.90{\mu}m$ (p<0.05). 2. The mean of marginal discrepancies for wax patterns was $10.65{\mu}m$. 3 The numbers of internal porosity showed the most in Runner bar group followed by Single group, Reservoir group, and Double group.

대한상한금궤의학회의 학생우수인재교육과정 개선을 위한 설문조사 연구

박재경,Park, Jae-Kyung 대한상한금궤의학회 2014 대한상한금궤의학회지 Vol.6 No.1

Objective : This Study aims to survey the current situation of the 'Future Leaders of Korean Medicine' curriculum and thereby improve the quality of the curriculum. Methods : 10 students in the curriculum answered 3 items of the NSSE questionnaires; 'Active and Collaborative Learning', 'Student-Faculty Interaction', 'Satisfaction'. Results : 'Worked with other students on projects', 'Tutored or taught other students (paid or voluntary)' average frequencies are relatively low in the 'Active and Collaborative Learning' item. 'Worked with faculty members on activities other than course-work' average frequency is relatively low in the 'Student-Faculty Interaction' item. Conclusions : The curriculum should be improved to encourage the students to take the leading roles at Collaborative Learning and to interact with the advisors.

국민학교 아동들의 양호실 인식도 및 이용도에 관한 연구

박재경,Park, Jae-Gyeong 한국지역사회간호학회 1990 지역사회간호학회지 Vol.2 No.1

국민학교 학동들의 양호실 인식도 및 이용도에 관한 연구

박재경,Park, Jae-Gyeong 한국지역사회간호학회 1990 지역사회간호학회지 Vol.2 No.1

Cervical Spondylotic Myelopathy 환자에게 소시호탕(小柴胡湯) 투여 후 발생한 약물유해반응에 관한 임상 보고

박재경,Park, Jae Kyung 대한상한금궤의학회 2017 대한상한금궤의학회지 Vol.9 No.1

Objective : The purpose of this paper is to report the adverse drug reactions of patient with cervical spondylotic myelopathy(CSM) treated by herb medicine, Soshiho-tang. Methods : The patient was prescribed Soshiho-tang herbal medicine for 9days. The patient complained of dizziness, difficulty of concentration and elevation of blood pressure on the 6th day. The doctor made the patient stop to take the herbal medicine and every symptoms and abnormal blood pressure are normalized after 6 days. The abnormal responses were assessed by WHO-UMC Causality Categories and LDS scale. Results : The WHO-UMC Causality is 'probable/likely' and LDS scale is 5, it means 'moderate' severity. Conclusions : The herbal medicine, Soshiho-tang is relevant to abnormal responses of the patient with CSM. This is a first case report of hypertension induced by herbal medicine, Soshiho-tang in Korea.

『상한론(傷寒論)』 변병진단체계(辨病診斷體系)에 준거하여 한약 투여 후 호전된 갱년기 증후군 1례 임상 보고

박재경,Park, Jae Kyung 대한상한금궤의학회 2016 대한상한금궤의학회지 Vol.8 No.1

Objective : This case report aims to demonstrate the effect of Herbal medicine on menopausal syndrome. Methods : A 54 years woman suffered from menopausal syndrome with hot flush, insomnia and dyspepsia. According to Diagnostic system based on Shanghanlun provisions, the patient was diagnosed with Taeyang-byung and treated by Sosiho-tang decoction at first. But the next time the patient visited, she was treated by Oryeong-san decoction. The result of administrations were evaluated by Kupperman's index(KI), Menopause rating scale(MRS). Results : After administration of Sosiho-tang decoction for 35 days, KI was decreased from 50 to 19, MRS was decreased from 9 to 4. But her chronic dyspepsia wasn't getting better. So the KMD prescribed Oryeong-san decoction. After administration of Oryeong-san decoction for 14 days, KI was decreased from 19 to 0, MRS was decreased from 4 to 1. And her chronic dyspepsia was functionally improved. Conclusions : The patient completely recovered from menopausal syndrome and dyspepsia as treated by Sosiho-tang decoction and Oryeong-san decoction according to Diagnostic system based on Shanghanlun provisions.