半夏瀉心湯이 CCl4 로 유도된 간중독 흰쥐에 미치는 영향

朱旺錫,朴賢俊,尹炳局,鄭成伊,朴宣東 대한본초학회 1999 大韓本草學會誌 Vol.14 No.2

The purpose of this study is to observe the effect of Banhasasimtang on serum reaction in CCI₄ treated rats. In this study the experimental rats divided five group(Normal, Control, Sample A, Sample B and Sample C group) Under the same condition Normal group was fed basal diet and water, Control group was injected carbon tetrachloride(CCI₄ 0.5㎖/㎏) and basal diet for 2 weeks, Sample A group was injected carbon tetrachloride(CCI₄0.5㎖/㎏) and fed the Bahasasimtang extract(10㎖/㎏) for 2 weeks, Sample A group was injected carbon tetrachloride(CCI₄ 0.5㎖/㎏) and fed the Banhasasimtang extract(10㎖/㎏) for 2 weeks, Sample B group was fed the Banhasasimtang extract(10㎖/㎏) for 2 weeks and injected carbon tetrachloride(CCI₄ 0.5㎖/㎏), Sample C group was fed the Banhasasimtang extract(10㎖/㎏) for 2 weeks. The change of GOT, GPT, γ-GPT, ALP, LDH activity and Bilirubin level in blood serum. The obtained results are summarized as follows : 1. In the change of GOT GPT contents, as compared with control group, sample group was significantly decreased. 2. In the change of γ-GPT contents, as compared wth control group, sample group was significantly decreased. 3. In the change of ALP contents, as compared with control group, sample group was significantly decreased. 4. In the change of LDP contents, as compared with control group, sample group was significantly decreased. 5. In the change of Bilirubin contents, as compared with control group, sample group was significantly decreased.

Effect of Hyulbuchukeotang and its component groups on diabetes, free radical and antioxidative defense system in alloxan-induced diabetic rats

박순동,주왕석,고원도 대한본초학회 2002 大韓本草學會誌 Vol.17 No.1

血府逐瘀湯과 그 構成藥物群이 Alloxan 糖尿 白鼠의 血淸 組成 및 抗酸化 效果에 미치는 影響

朴宣東,朱旺錫,高元道 대한본초학회 2002 大韓本草學會誌 Vol.17 No.1

This study was reseached to investigate the effect of Hyulbuchukeotant(?????) and its component groups on diabetes, free radical and antioxidative defense system in alloxan-induced diabetic rats, The experimental group was divided into three groups: Hyulbuchukeotang (HCT), and its components groups, Sayeoksan(H-sa) and Dohong- samultant(H-do). The results were obtained as follows: In the study of effect on diabetes, the level of glucose was considerablely reduced by HCT, H-sa and H-do with high significancy. In the change of fat metabolism, all experimental groups significantly changed the level of triglyceride, total cholesterol and HDL cholesterol expecially HCT and H-do group, but H-sa group has less significancy. In the change of protein metabolism, all experimental groups changed the level of total protein and albumin with high significancy. In the change of kidney function, HCT decreased the level of creatinine and BUN with high significancy, H-sa and H-do did with some significancy too. In the study on free radical scavenging effect in vitro, it has shown that all experimental groups have significant suppressing effect on peroxidation of linoleic acid on concentration, and in the scavenging effect of DPPH radical, inhibitory effect of superoxide in xanthine-xanthine oxidase system and inhibitory effect on lipid peroxidation reaction by hydroxy radical in H₂O₂-Fe^2+ system, all experimental groups have some activity. In the study on antioxidative defense system in vivo, HCT reduced the amount of lipid peroxide in serum and liver with high significantcy, and H-sa, H-do group did too with some significancy. In hepatic catalase activity, all experimental groups had showed activity on catalase, but H-sa no significancy. In the level of hepatic hlutathione, HCT increased the amount of glutathione significantly, but other groups with no significancy. In the activity of glutathione-s-transferase, all experimental groups has decreasing effect with significancy. These results suggest that Hyulbuchukeotant(?????) has strong effect on diabetes and peroxidative damage by free radical, so it is useful to prevent diabetes.

歸脾湯 및 그 構成藥物群이 抗酸化效果에 미치는 영향

朴宣東,朴賢俊,朱旺錫 대한본초학회 2001 大韓本草學會誌 Vol.16 No.1

This study was performed to research the antioxidant activities of Guibitang and its component groups. The experimental group was divided into six group: Guibitang (GB), Gamiguibitang (GA), Hyul-yak group (GB1), Gi-yak group (GB2), Ansinhaenggi-yak group (GB3) and Gami-yak group (GA1). The results were obtained as follows: In vitro All experimental groups had antioxidant activity in linoleic acid system on concentration in comparison with control group. And in DPPH radical scavenging experiment, all experimental groups had scavenging activity on concentration, especially GA1 group was higher than any others. The inhibitory effect experimental groups had inhibitory effects of superoxide generation on concentration, and the effect of Guibitang was better than Gamiguibitang. In component groups GA1 was highest and GB1 was lowest respectively. The inhibitory effect experiment on lipid peroxidation reaction in H₂O₂-Fe^2+ system showed that each experimental groups had inhibitory effects on lipid peroxidation reaction compared with control group. And GA1 group exhibit the best inhibition effect on lipid peroxidation reaction. In vivo the amounts of lipid peroxide rat on the level of serum was reduced in comparison with control group, especially gamiguibitang. The amounts of LPO on the level of liver was also reduced compared with control group. espeially gamiguibitang, guibitang, GB1 group. In hepatic catalase activity test, all experimental groups increased catalase activity, and that of guibitang, gamiguibitang, GB1 group were evident. The amounts of hepatic glutathione of experimental group increased in comparison with control group. And that of gamiguibitang, guibitang was more significant than component group.

전신조정술 중재가 자세조절에 미치는 효과

문상은,김미화,주왕석,이수홍,오창선,최민호,정웅채 대한침구의학회 2009 대한침구의학회지 Vol.26 No.5

Objectives : This study was designed to analyze whether General Coordinative Manipulation(GCM) Intervention could have effects on the balanced restoration of asymmetrical posture. Methods : Sixty eight(68) healthy volunteers(1st hypothesis: 46, 2nd hypothesis 22) participated in two GCM interventions, which have been performed 2 times a week for 3 weeks. The Global Postural System(GPS) Unit was used to measure the posture, and measurements were performed before and after the application of each intervention group. A paired t-test and wilcoxon test were used to determine the statistical significance. Results : The outcome of examining the hypothesis is as follows: 1. The 1st hypothesis : It has been proved that GCM Intervention, which coordinates the flexion type of upper extremity and the extension type of lower extremity, excluding self-care, shows the efficiency in treatment on more than two aspects of 3 parts: anterior, posterior and lateral postures, and the effects on more than 3 of 4 body types. 2. The 2nd hypothesis : It has been proved that GCM Intervention, which coordinates the flexion type of lower extremity and the extension type of upper extremity, excluding self-care, shows the treatment in efficiency on more than two aspects of 3 parts: anterior, posterior and lateral postures, and the effects on more than 2 of 3 body types. Conclusions : GCM intervention programs on the two hypothesis groups have an affect on the balanced restoration of the postural control system.

상.하체의 굽힘.폄 양상에 따른 전신조정술 접근 모형이 대학생의 보행에 미치는 영향

문상은,김미화,주왕석,이수홍,오창선,최민호,정웅채,Moon, Sang-Eun,Kim, Mi-Hwa,Ju, Wang-Suck,Lee, Su-Hong,Oh, Chang-Sun,Choi, Min-Ho,Jung, Woong-Chae 대한물리치료과학회 2009 대한물리치료과학회지 Vol.16 No.2

Background: The musculoskeletal disorders with asymmetrical gait on the whole body are the most common. This study was designed to analyze that General Coordinative Manipulation Intervention Models would affect the balanced restoration of asymmetrical gait. Methods: 68 healthy volunteers(1st hypothesis: 46, 2nd hypothesis 22) participated in the two GCM intervention models, which have performed 2 times a week for 3 weeks. Digital Camera was used to measure the gait, and measurements were performed before and after the application of the each intervention model. Repeated measured ANOVA was used to determine a statistical significance. Results: The outcome of examining hypothesis is as follows: 1. The 1st hypothesis : GCM Intervention based on the coordinating the flexion type of upper body and the extension type of lower body will improve in the balanced restoration of asymmetrical gait because it offers a clear direction for treatment(p<.05). 2. The 2nd hypothesis: GCM Intervention based on the coordinating the flexion type of lower body and the extension type of upper body will improve in the balanced restoration of asymmetrical gait because it offers a clear direction for treatment(p<.05). Conclusion: GCM intervention programs on the two hypothesis groups have effects on the balanced restoration of asymmetrical gait(p<.05).