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      • KCI등재후보

        소아에서 신장 이식 후 발생한 Posttransplant Lymphoproliferative Disease 1례

        장원경,한혜원,이미정,김태형,박영서,Jhang Won-Kyoung,Hahn Hye-Won,Lee Mee-Jeung,Ghim Thad-T.,Park Young-Seo 대한소아신장학회 2003 Childhood kidney diseases Vol.7 No.2

        Posttransplant lymphoproliferative disease(PTLD)는 이식 후 발생하는 림프증식성 질환으로 이식장기의 거부반응을 억제하기 위한 면역억제제의 사용 및 이에 따른 EBV 감염과 연관이 있다고 알려져 있다. 소아 PTLD의 경우 성인에 비해 EBV의 초감염 또는 재활성이 더 많은 것으로 보고되고 있으며 최근 더 강력한 면역억제제들의 개발 및 사용에 따라 발생이 증가하고 있다. 본 증례는 14세 여아로 신이식 44개월 후에 EBV 감염의 증거 없이 지발성 PTLD가 발생하였으며 골수 검사상 B-세포 급성 림프구성 백혈병으로 진단되어 항암화학요법 치료를 시작하였고, 치료 후 완전 관해는 이루어졌으나 심한 중성구 감소증에 따른 패혈성 쇼크로 입원 77일만에 사망하였다. Posttransplant lymphoproliferative disease(PTLD) has emerged as a potential life-threatening complication of immunosuppressive therapy after organ transplantation. The occurrence of PTLD is usually associated with an Epstein-Barr virus(EBV) infection in patients who are treated by aggressive immunosuppressive therapy. PTLD is represented by diverse manifestations ranging from reactive lymphoid hyperplasia to high grade malignant lymphoma. This is a case report of a late PTLD in a child. The patient is a 14-year-old girl, who presented as malignant lymphoma 44 months after successful renal transplantation. There was no evidence of EBV infection. On bone marrow study, many neoplastic lymphoid cells were defected. Aggressive chemotherapy for PTLD had resulted in clinical remission. However the patient expired from uncontrolled sepsis and septic shock after 77 days.

      • KCI등재후보

        인터넷 사용 환경에서의 조직문화에 관한 연구

        장원경,민경호,김태균 대한경영학회 2002 大韓經營學會誌 Vol.15 No.4

        The World Wide Web and electronic commerce have grown radically since its inception in 1990 by an average annual growth rate over 100%. The Internet's growth makes the creation of cyber markets and it changes management environments. Information Technology (IT) is the essential element of a firm's development and its survival. The Technology Acceptance Model (TAM) represents an important theoretical contribution toward understanding computer usage and computer acceptance behaviors. The current studies investigated the relationships between organizational tasks and internet using TAM. For using internet, social network is important because the natural characteristic of internet is community-based. However, TAM is incomplete in one important respect: it doesn't account for social influence in the adoption and utilization of new information system. So, organizational culture (OC), that we believe to be important, plays a role in explaining their internet usage. OC will affect user attitude. We extend and empirically validate the TAM for the internet usage including OC. The findings enable future researchers and practitioners to account for social influence in future investigator of TAM. Extending the Technology Acceptance Model to Account for Organizational Culture Won Kyung Changfor the internet usage including OC. The findings enable future researchers and practioners to account for social influence in future investigator of TAM.The World Wide Web and electronic commerce have grown radically since its inception in 1990 by an average annual growth rate over 100%. The Internet's growth makes the creation of cyber markets and it changes management environments. Information Technology (IT) is the essential element of a firm's development and its survival. The Technology Acceptance Model (TAM) represents an important theoretical contribution toward understanding computer usage and computer acceptance behaviors. The current studies investigated the relationships between organizational tasks and internet using TAM. For using internet, social network is important because the natural characteristic of internet is community-based. However, TAM is incomplete in one important respect: it doesn't account for social influence in the adoption and utilization of new information system. So, organizational culture (OC), that we believe to be important, plays a role in explaining their internet usage. OC will affect user attitude. We extend and empirically validate the TAM for the internet usage including OC. The findings enable future researchers and practitioners to account for social influence in future investigator of TAM.

      • KCI등재후보

        전자상거래에서 사회적변수가 신뢰에 미치는영향에 관한 연구

        장원경,이황연 대한경영학회 2004 大韓經營學會誌 Vol.17 No.5

        Recently, the number of domestic internet users and the scale of electronic commerce (EC) are increasing rapidly due to the development of information technology and internet. However, the proportion of purchasing consumers among internet users is quite small, and online purchasing has yet to truly take-off. A major reason for this lack of online purchases is that consumers are not willing to join EC because of a lack of trust in electronic retailers or internet vendors. The degree of trust is one of the major determinants of the success of B2C electronic commerce. Trust has been identified as a key component in many marketing and EC studies.Focusing on the critically important issue of trust in B2C EC, this study analyzes the effects of social variables - including word-of-mouth, subjective norms, and customer testimonials - on online trust. Moreover, the study examines the relationship between trust, perceived risk, and intention to transact. A theoretical framework was presented, based on an extensive literature review, and an empirical analysis was preformed, based on survey responses of those who have experience visiting internet shopping malls.Results of this study are as follows:First, social variables (word-of-mouth, subjective norms, customer testimonials) positively influence online trust concerning B2C EC. Second, trust has significant effects on the online intention to transact. Third, trust has negative effects on the internet shopping mall's perceived risk. However, perceived risk does not significantly affect online intention to transact. In conclusion, we can say that trust in internet shopping is mainly affected by external factors, word-of-mouth, subjective norms and customer testimonials. Thus, businesses trying to spur the development of internet shopping malls can apply social variables to their business strategy. 인터넷의 확산과 정보기술의 발전으로 전자상거래의 급속한 증가를 가져 왔다. 그러나 기업과 소비자간 전자상거래의 시장규모와 거래량이 늘어가고 있으나, 인터넷쇼핑몰에 대한 신뢰는 매우 낮은 수준이고, 극히 소수의 쇼핑몰로만 사람들이 몰리고 있다.본 연구는 기업과 소비자간 전자상거래에서 신뢰의 중요성을 인식하고, 전자상거래에서 사회적인 관계에서 상호간의 행위에 의해 영향을 주고받는 의미에서 구전, 주관적 규범, 고객추천서 등의 사회적 변수가 신뢰에 미치는 영향과 지각된 위험이 소비자의 구매의도에 미치는 영향에 관한 모형을 제시하여 실증적으로 분석하고자 하였다.연구결과 사회적 변수인 구전, 주관적 규범, 고객추천서는 신뢰에 긍정적인 영향을 주며, 신뢰가 구매의도에 영향을 주는 것으로 나타났다. 그러나 지각된 위험은 구매의도에 유의미한 영향이 없음이 밝혀졌다. 이 연구결과는 전자상거래에 관련이 있는 실무자나 연구자들에게 많은 시사점을 줄 것이다.

      • KCI등재후보

        중소기업 회계담당자의 회계프로그램 수용에 관한 연구 - 지각된 자원의 역할을 중심으로 -

        장원경,신건권,김태균 한국회계정보학회 2005 회계정보연구 Vol.23 No.1

        TAM(Technology Acceptance Model) supports the notion that perceived usefulness and perceived ease of use are primary drivers of user intentions to adopt new information technology in many studies. However, TAM focused on volitional choices and were intended only to explain volitional behavior. And, many of the behaviors in organizations, particularly those related to technology, are not volitional. When technology adoption is mandated, as it is in many SMEs, we expected that the underlying relationships of traditional TAM will be different.The results showed that perceived resource significantly influenced perceived ease of use and perceived usefulness. And perceived resource affected behavioral intention indirectly through perceived usefulness. Also perceived resource is shown to play a significant role in explaining mandatory environments than voluntary environments. 기술수용모형(Technology Acceptance Model: TAM)은 많은 연구를 통해서 지각된 이용용이성과 지각된 유용성이 새로운 정보기술을 수용하는데 가장 중요한 변수로 나타났다. 현재까지의 TAM연구는 주로 사용자의 자발적 수용에 초점이 맞추어져 연구되었으나, 대부분의 중소규모 조직의 정보기술 수용환경이 자발적인 경우는 매우 드물다. 정보기술 수용이 비자발적 환경에서는 과거의 자발적 TAM연구와는 다른 결과로 나타날 것이며 이에 대한 연구가 요구된다.따라서 본 연구에서는 중소기업 회계담당자들의 회계프로그램 수용에 있어 지각된 자원을 역할을 규명하고자 한다. 세부적으로는 첫째, 정보기술 수용에 선택권한이 주어지지 않는 비자발적 환경 하에서의 PR과 TAM 관계성을 살펴본다. 둘째, 자발적 수용에 대한 선행연구와 비교하여 비자발적 수용에 대한 연구에서 PR의 역할을 분석하여 차이점에 있는가를 분석한다.연구 결과 비자발적인 환경에서 지각된 자원은 지각된 이용용이성과 지각된 유용성에 정의 영향을 미치고 있으며, 행동의도에 간접적인 영향을 미치는 것으로 나타났다.

      • KCI등재

        Severe hypermagnesemia presenting with abnormal electrocardiographic findings similar to those of hyperkalemia in a child undergoing peritoneal dialysis

        장원경,이윤정,김영아,박성종,박영서 대한소아청소년과학회 2013 Clinical and Experimental Pediatrics (CEP) Vol.56 No.7

        In this report, we present a pediatric case of severe symptomatic hypermagnesemia resulting from the use of magnesium oxide as a laxative in a child undergoing continuous cyclic peritoneal dialysis for end-stage renal disease. The patient showed abnormal electrocardiography (ECG) findings, such as tall T waves, a widened QRS complex, and irregular conduction, which were initially misdiagnosed as hyperkalemia; later, the correct diagnosis of hypermagnesemia was obtained. Emergent hemodialysis successfully returned the serum magnesium concentration to normal without complications. When abnormal ECG changes are detected in patients with renal failure, hypermagnesemia should be considered.

      • KCI등재후보

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