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切斷性 神經腫痛에 對한 새로운 治療法 : Ⅰ. 實驗的 觀察
沈輔星,金永基,尹金重,崔吉洙 서울대학교 1966 서울대학교 論文集 Vol.17 No.-
In an effort to supress pain from amputation neuroma, the neuroma bearing nerve was transected and re-sutured at various points proximal to the neuroma, and obtained very satisfactory results in eight patients. In this study the unilateral sciatic nerves of dogs and rabbits were severed at three points, each one cm. apart, and resutured, and the opposits sciatic nerves were simply amputated, in order to obesrve the regenerative process of the nerve fibers thorough the cut-resutured lines and formation of neuroma. These experimental animals were observed for two months, and under Nembutal general anesthesia each specimen was removed. For microscopic examination these specimens were stained with hematoxilin-eosin, Trichrom and silver staining methods. Results were as follows: 1. All animals subjected to the experiments developed sings of sciatic nerve palsy. During the observation period of two months, there were no evidence of substantial recovery of the lost function. 2. The proximal stumps of all severed nerves formed neuroma of slight to marked degree and except in two dogs the distal stumps were seen to have formed gliomas. On microscopical sections, many fibers were seen to be growing through the scartissue which occupied 1.5 cm. gap between cut ends. The distal nerve fibers underwent advanced Wallerian degeneration, as expected. 3. There were evidences of active regeneration of axons far beyond the segments, which were severed and resutured in three points at interval of one cm. However, comparing with mother fibers, regenerating daughter fibers were reduced in number and size and their architectures were disorganized, the number of daughter fibers regenerated through third sutured line was reduced to one-third that of original fibers, and the structural completion was less. It is probable that this ratio would be more reduced if the distances between transections were more farther apart, or performed in human
저부하 HCCI 운전모드에서의 불완전 연소에 대한 조사
김동우(Tongwoo Kim),윤금중(Keumjoong Yoon),Jaal B. Ghandhi 한국자동차공학회 2004 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-
Planar laser-induced fluorescence of formaldehyde was used to investigate quenching of the homogeneous-charge compression-ignition (HCCI) combustion process at light load in an n-heptane-fueled internal combustion engine. Detailed chemical kinetic calculations indicated that the persistence of formaldehyde after the end of heat release coincided with the existence of a significant mole fraction of carbon monoxide at the end of the cycle. At fuel-air equivalence ratios greater than 0.16 the data indicate that formaldehyde is uniformly formed within the combustion chamber during the first-stage ignition, and then completely consumed during the second-stage ignition event. However, at low equivalence ratios the formaldehyde fluorescence was found to persist late into the expansion stroke after all heat release was completed. The imaged region was far from the combustion chamber surfaces so the persistence of the formaldehyde fluorescence is considered to be the result of bulk gas quenching.
전제록(Jerok Chun),윤금중(Kumjung Yoon) 한국자동차공학회 2004 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-
Injector modification, Oil ring tension reduction and Oil pump rotor re-matching with optimization of relevant control parameters drived fuel consumption reduction of HSDI diesel engine. Injector was modified and evaluated in view of fuel economy and emission trade-offs. With introducing smaller nozzle hole diameter PM (particulate matter) was enormously decreased in lower rpm/lower BMEP area. Some hardware were modified for reducing mechanical friction and proved to be better fuel economy. Specially ECU data optimization was a great help to 1ow fuel consumption. The influence of calibration parameters including pilot quantity, pilot interval, air mass and main injection timing on fuel economy, smoke and NOx has been evaluated in the typical 14 points from NEDC cycle. The fuel consumption was proved to 7% improvement in the engine bench and 3.7% in the vehicle.
金輔星,朱正和,朱東善,尹金重,崔吉洙,徐浚根 中央醫學社 1964 中央醫學 Vol.7 No.6
So far various drugs have been tried for the treatment of pulmonary paragonimiasis without any appreciable effect. Since the first report of Yokogawa on an excellent result of Bithionol for the treatment of pulmonary paragonimiasis in 1960 many reports have been published with same excellent results. However, there has been no trial of this drug for the treatment of cerebral parago nimiasis. This study is intended to investigate the effect of Bithionol on the cerebral paragonimiasis. Bithionol is given to 18 patients with cerebral paragonimiasis in a dose of 4050 mg/kg body weight per day, every other day for one month. Daily dose was divided into three and given post-prandially. Following results are obtained: ① In no case, the negative conversion of the eggs per day (E.P.D.) occured in the first ten days after initiation of therapy, in 58% of cases in the second ten days, in 33 % in the last ten days. In one case, the negative conversion was observed at the 31st day of treatment. In a series of patients in whose stool egg of paragonimus was found, the negative conversion of E.P.G. occurred in 75% in the second ten days and 25% in the last ten days. ② In six cases with meningitis symptoms, meningeal symptom have cleared up within the first ten days which had been also proved by the spinal. fluid findings. ③ Major symptoms of pulmonary paragonimiasis such as bloody sputum, fish oder, sputum, and hemoptysis had disappeared in 55% of cases in the first ten days, in 31% in the second ten days, and 14% in the last ten days. ④ Side effects of Bithionol had occured as follows; diarrhea in 25. 8% of cases, dizziness in 12.6%o anorexia in 9.9%, abdominal pain in 12. 6% indigeston in 9. 9%, mild fever in 6. 4%, generalized muscular pain in 3. 2%, erythema in 9. 9% eruption in 6. 4%, and itching in 3. 2%. ⑤ Meningeal irritation signs such as headache, stiffneck and vomiting had disappeared in the first 20 days after treatment in all cases except for 3 cases in which headaehe has persist until the end of one course. ⑥ Improvement of focal symptoms or convulsions typical for the chronic form of cerebral paragonimiasis was not so appreciable, but aggrevation of symptoms is not observed in any of our cases. ⑦ From these, it can be concluded that Bithional is effective for the treatment of cerebral paragonimiasis, especially in the acute forms of cerebral paragonimiasis.
DoE를 이용한 승용디젤엔진의 Emission 매핑 최적화
조청훈(Chunghoon Jo),윤금중(Kumjung Yoon) 한국자동차공학회 2005 한국자동차공학회 춘 추계 학술대회 논문집 Vol.2005 No.11_1
To cope with the more stringent emission regulations, now diesel engines for passenger car adopt various tools like variable geometry Turbocharger, EGR, variable swirl system and multiple injection FIE system. On the other hands, these new tools cause difficulties to optimize so many mapping parameters which affect performance and emissions, at the same time. This paper presents the process of mapping optimization using DoE method and optimized result of passenger car diesel engine.